The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes.

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Published in Proc Natl Acad Sci U S A on October 17, 2007

Authors

Janet M Wenzlau1, Kirstine Juhl, Liping Yu, Ong Moua, Suparna A Sarkar, Peter Gottlieb, Marian Rewers, George S Eisenbarth, Jan Jensen, Howard W Davidson, John C Hutton

Author Affiliations

1: Barbara Davis Center for Childhood Diabetes, University of Colorado at Denver and Health Sciences Center, 1775 North Ursula Street, Aurora, CO 80045, USA.

Associated clinical trials:

T1DM Immunotherapy Using CD4+CD127lo/-CD25+ Polyclonal Tregs (Treg) | NCT01210664

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