NHS-IL12 for Solid Tumors

Clinical Trial ID NCT01417546

PubWeight™ 9.86‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01417546

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The development of immunoconjugates for targeted cancer therapy. Nat Rev Clin Oncol 2014 1.49
2 Phase I trial of twice-weekly intravenous interleukin 12 in patients with metastatic renal cell cancer or malignant melanoma: ability to maintain IFN-gamma induction is associated with clinical response. Clin Cancer Res 2000 1.38
3 Trial Watch: Immunostimulatory cytokines. Oncoimmunology 2012 1.19
4 Antibody-Dependent Cellular Cytotoxicity Activity of a Novel Anti-PD-L1 Antibody Avelumab (MSB0010718C) on Human Tumor Cells. Cancer Immunol Res 2015 1.18
5 Interleukin 12: still a promising candidate for tumor immunotherapy? Cancer Immunol Immunother 2014 1.17
6 New insights into IL-12-mediated tumor suppression. Cell Death Differ 2014 1.09
7 Peripheral burst of tumor-specific cytotoxic T lymphocytes and infiltration of metastatic lesions by memory CD8+ T cells in melanoma patients receiving interleukin 12. Cancer Res 2000 1.03
8 Phase I study of subcutaneously administered recombinant human interleukin 12 in patients with advanced renal cell cancer. Clin Cancer Res 1999 0.91
9 The tumor microenvironment in esophageal cancer. Oncogene 2016 0.83
10 The immunocytokine NHS-IL12 as a potential cancer therapeutic. Oncotarget 2014 0.83
11 Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma. PLoS One 2015 0.77
12 Antibody-cytokine fusion proteins for treatment of cancer: engineering cytokines for improved efficacy and safety. Semin Oncol 2014 0.77
13 Defining the Value of a Comparative Approach to Cancer Drug Development. Clin Cancer Res 2015 0.77
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