Safety Study of IL-21/Anti-PD-1 Combination in the Treatment of Solid Tumors

Clinical Trial ID NCT01629758

PubWeight™ 44.77‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01629758

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J Clin Oncol 2014 9.86
2 Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer. Clin Cancer Res 2013 3.48
3 Breathing new life into immunotherapy: review of melanoma, lung and kidney cancer. Nat Rev Clin Oncol 2013 2.64
4 The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma. Clin Ther 2015 1.73
5 Emerging targeted agents in metastatic breast cancer. Nat Rev Clin Oncol 2013 1.59
6 Combination cancer immunotherapies tailored to the tumour microenvironment. Nat Rev Clin Oncol 2015 1.54
7 Trial watch: Monoclonal antibodies in cancer therapy. Oncoimmunology 2013 1.41
8 Intratumoral immunization: a new paradigm for cancer therapy. Clin Cancer Res 2014 1.24
9 Nivolumab in NSCLC: latest evidence and clinical potential. Ther Adv Med Oncol 2015 1.21
10 Development of PD-1/PD-L1 Pathway in Tumor Immune Microenvironment and Treatment for Non-Small Cell Lung Cancer. Sci Rep 2015 1.18
11 Pathways and therapeutic targets in melanoma. Oncotarget 2014 1.17
12 Molecular pathways and therapeutic targets in lung cancer. Oncotarget 2014 1.16
13 Immune modulation for cancer therapy. Br J Cancer 2014 1.15
14 Nivolumab in melanoma: latest evidence and clinical potential. Ther Adv Med Oncol 2015 1.09
15 Cancer immunotherapy in clinical practice -- the past, present, and future. Chin J Cancer 2014 0.98
16 Trial Watch: Immunostimulatory cytokines. Oncoimmunology 2013 0.96
17 Checkpoint modulation in melanoma: an update on ipilimumab and future directions. Curr Oncol Rep 2013 0.94
18 New modalities of cancer treatment for NSCLC: focus on immunotherapy. Cancer Manag Res 2014 0.94
19 Immune checkpoint blockade in cancer treatment: a double-edged sword cross-targeting the host as an "innocent bystander". Toxins (Basel) 2014 0.92
20 The future of glioblastoma therapy: synergism of standard of care and immunotherapy. Cancers (Basel) 2014 0.91
21 Immunotherapy for prostate cancer: recent developments and future challenges. Cancer Metastasis Rev 2014 0.90
22 Anticancer Cytokines: Biology and Clinical Effects of Interferon-α2, Interleukin (IL)-2, IL-15, IL-21, and IL-12. Semin Oncol 2015 0.89
23 Recombinant interleukin-21 plus sorafenib for metastatic renal cell carcinoma: a phase 1/2 study. J Immunother Cancer 2014 0.83
24 IL-21: a pleiotropic cytokine with potential applications in oncology. J Immunol Res 2015 0.83
25 Immunotherapy for solid tumors--a review for surgeons. J Surg Res 2013 0.83
26 Tertiary Lymphoid Structures in Cancers: Prognostic Value, Regulation, and Manipulation for Therapeutic Intervention. Front Immunol 2016 0.83
27 Targeting CD8+ T-cell tolerance for cancer immunotherapy. Immunotherapy 2014 0.81
28 Clinical utility of nivolumab in the treatment of advanced melanoma. Ther Clin Risk Manag 2016 0.81
29 PD-1 and PD-L1 antibodies for melanoma. Hum Vaccin Immunother 2014 0.80
30 Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8+ T-Cell Population in Elite Controllers. J Infect Dis 2015 0.80
31 Immune Checkpoint Modulation in Colorectal Cancer: What's New and What to Expect. J Immunol Res 2015 0.78
32 Trial watch: Tumor-targeting monoclonal antibodies for oncological indications. Oncoimmunology 2015 0.77
33 Trial Watch-Immunostimulation with cytokines in cancer therapy. Oncoimmunology 2015 0.77
34 Adding fuel to the fire: immunogenic intensification. Hum Vaccin Immunother 2014 0.75
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