Ipilimumab With or Without Talimogene Laherparepvec in Unresected Melanoma

Clinical Trial ID NCT01740297

PubWeight™ 35.31‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01740297

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Localized oncolytic virotherapy overcomes systemic tumor resistance to immune checkpoint blockade immunotherapy. Sci Transl Med 2014 2.82
2 Breathing new life into immunotherapy: review of melanoma, lung and kidney cancer. Nat Rev Clin Oncol 2013 2.64
3 At the bedside: CTLA-4- and PD-1-blocking antibodies in cancer immunotherapy. J Leukoc Biol 2013 1.90
4 Defining Effective Combinations of Immune Checkpoint Blockade and Oncolytic Virotherapy. Clin Cancer Res 2015 1.61
5 Randomized, Open-Label Phase II Study Evaluating the Efficacy and Safety of Talimogene Laherparepvec in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced, Unresectable Melanoma. J Clin Oncol 2017 1.39
6 Trial watch: Oncolytic viruses for cancer therapy. Oncoimmunology 2013 1.36
7 Cancer immunotherapy: the beginning of the end of cancer? BMC Med 2016 1.32
8 Talimogene Laherparepvec in Combination With Ipilimumab in Previously Untreated, Unresectable Stage IIIB-IV Melanoma. J Clin Oncol 2016 1.32
9 Intratumoral immunization: a new paradigm for cancer therapy. Clin Cancer Res 2014 1.24
10 Trial Watch: Immunostimulatory monoclonal antibodies in cancer therapy. Oncoimmunology 2014 1.22
11 Checkpoint modulation in melanoma: an update on ipilimumab and future directions. Curr Oncol Rep 2013 0.94
12 Evidence for Oncolytic Virotherapy: Where Have We Got to and Where Are We Going? Viruses 2015 0.92
13 Immune checkpoint blockade in cancer treatment: a double-edged sword cross-targeting the host as an "innocent bystander". Toxins (Basel) 2014 0.92
14 Updates in Therapy for Advanced Melanoma. Cancers (Basel) 2016 0.91
15 Moving oncolytic viruses into the clinic: clinical-grade production, purification, and characterization of diverse oncolytic viruses. Mol Ther Methods Clin Dev 2016 0.86
16 Oncolytic virus therapy: A new era of cancer treatment at dawn. Cancer Sci 2016 0.86
17 Overcoming Barriers in Oncolytic Virotherapy with HDAC Inhibitors and Immune Checkpoint Blockade. Viruses 2016 0.85
18 Talimogene laherparepvec (T-VEC) for the treatment of advanced melanoma. Immunotherapy 2015 0.83
19 Replication-Competent Viruses as Cancer Immunotherapeutics: Emerging Clinical Data. Hum Gene Ther 2015 0.83
20 Trial Watch-Oncolytic viruses and cancer therapy. Oncoimmunology 2015 0.83
21 Oncolytic adenovirus research evolution: from cell-cycle checkpoints to immune checkpoints. Curr Opin Virol 2015 0.82
22 Immunotherapy: Combined immunotherapy--a new standard in metastatic melanoma? Nat Rev Clin Oncol 2015 0.81
23 Have lessons from past failures brought us closer to the success of immunotherapy in metastatic pancreatic cancer? Oncoimmunology 2015 0.78
24 Personalized virotherapy in cancer. Aging (Albany NY) 2015 0.78
25 Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015. J Transl Med 2016 0.77
26 Developments in Intralesional Therapy for Metastatic Melanoma. Cancer Control 2016 0.77
27 Combination Approaches with Immune-Checkpoint Blockade in Cancer Therapy. Front Oncol 2016 0.77
28 Viro-immune therapy: A new strategy for treatment of pancreatic cancer. World J Gastroenterol 2016 0.77
29 Chemovirotherapy: combining chemotherapeutic treatment with oncolytic virotherapy. Oncolytic Virother 2015 0.76
30 Future perspectives in melanoma research : Meeting report from the "Melanoma Bridge". Napoli, December 1st-4th 2015. J Transl Med 2016 0.76
31 Combining talimogene laherparepvec with immunotherapies in melanoma and other solid tumors. Cancer Immunol Immunother 2017 0.75
32 Spotlight on talimogene laherparepvec for the treatment of melanoma lesions in the skin and lymph nodes. Oncolytic Virother 2016 0.75
33 Prime time for immune-checkpoint targeted therapy at ASCO 2015. Oncoimmunology 2015 0.75
34 Ipilimumab (Anti-Ctla-4 Mab) in the treatment of metastatic melanoma: Effectiveness and toxicity management. Hum Vaccin Immunother 2016 0.75
35 Immune-checkpoint blockade: the springboard for immuno-combination therapy. Gene Ther 2015 0.75
36 The Role of Regional Therapies for in-Transit Melanoma in the Era of Improved Systemic Options. Cancers (Basel) 2015 0.75
37 Critical analysis of an oncolytic herpesvirus encoding granulocyte-macrophage colony stimulating factor for the treatment of malignant melanoma. Oncolytic Virother 2014 0.75
38 Oncolytic herpes viruses, chemotherapeutics, and other cancer drugs. Oncolytic Virother 2013 0.75
39 Efficacy and safety of talimogene laherparepvec versus granulocyte-macrophage colony-stimulating factor in patients with stage IIIB/C and IVM1a melanoma: subanalysis of the Phase III OPTiM trial. Onco Targets Ther 2016 0.75
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