Effect of AT-derived miRNA on the Biology and Insulin Sensitivity of Skeletal Muscle in Humans (miRNA)

Clinical Trial ID NCT02459106

PubWeight™ 0.00‹?›

🔗 Visit the ClinicalTrials.gov page for NCT02459106

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification of novel genes coding for small expressed RNAs. Science 2001 44.44
2 An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 2001 44.16
3 An extensive class of small RNAs in Caenorhabditis elegans. Science 2001 34.17
4 Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 2008 32.08
5 Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 2000 19.15
6 Obesity wars: molecular progress confronts an expanding epidemic. Cell 2004 5.29
7 MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity. Diabetes 2009 3.02
8 miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARgamma expression. Biochem Biophys Res Commun 2010 2.28
9 Mir193b-365 is essential for brown fat differentiation. Nat Cell Biol 2011 2.20
10 microRNA miR-27b impairs human adipocyte differentiation and targets PPARgamma. Biochem Biophys Res Commun 2009 1.98
11 Endocrine and signalling role of adipose tissue: new perspectives on fat. Acta Physiol Scand 2005 1.94
12 MiRNA expression profile of human subcutaneous adipose and during adipocyte differentiation. PLoS One 2010 1.89
13 MicroRNA expression in human omental and subcutaneous adipose tissue. PLoS One 2009 1.81
14 In vivo regulation of lipolysis in humans. J Lipid Res 1994 1.70
15 Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes. Diabetologia 2010 1.60
16 Circulating miRNAs: cell-cell communication function? Front Genet 2013 1.55
17 miR-519d overexpression is associated with human obesity. Obesity (Silver Spring) 2010 1.54
18 Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis. Genome Biol 2011 1.53
19 Adipose tissue exosome-like vesicles mediate activation of macrophage-induced insulin resistance. Diabetes 2009 1.42
20 Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation. Biochem Biophys Res Commun 2010 1.20
21 Targeting microRNAs in obesity. Expert Opin Ther Targets 2009 1.14
22 Human adipose microRNA-221 is upregulated in obesity and affects fat metabolism downstream of leptin and TNF-α. Diabetologia 2013 1.03
23 Autocrine action of adiponectin on human fat cells prevents the release of insulin resistance-inducing factors. Diabetes 2005 1.00
24 Impairment of insulin signaling in human skeletal muscle cells by co-culture with human adipocytes. Diabetes 2002 0.93
Next 100