Vitamin C in Post-cardiac Arrest (VITaCCA)

Clinical Trial ID NCT03509662

PubWeight™ 0.00‹?›

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 A randomized trial of glutamine and antioxidants in critically ill patients. N Engl J Med 2013 8.94
2 High-protein enteral nutrition enriched with immune-modulating nutrients vs standard high-protein enteral nutrition and nosocomial infections in the ICU: a randomized clinical trial. JAMA 2014 4.53
3 Vitamin C pharmacokinetics: implications for oral and intravenous use. Ann Intern Med 2004 4.30
4 The role of neutrophils in myocardial ischemia-reperfusion injury. Cardiovasc Res 1999 2.27
5 Phase I clinical trial of i.v. ascorbic acid in advanced malignancy. Ann Oncol 2008 2.27
6 Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients. Ann Surg 2002 1.92
7 Early enteral supplementation with key pharmaconutrients improves Sequential Organ Failure Assessment score in critically ill patients with sepsis: outcome of a randomized, controlled, double-blind trial. Crit Care Med 2008 1.71
8 Reduction of resuscitation fluid volumes in severely burned patients using ascorbic acid administration: a randomized, prospective study. Arch Surg 2000 1.63
9 Impact of high-dose antioxidants on outcomes in acutely injured patients. JPEN J Parenter Enteral Nutr 2008 1.52
10 Fundamentals of reperfusion injury for the clinical cardiologist. Circulation 2002 1.49
11 Postresuscitation syndrome: potential role of hydroxyl radical-induced endothelial cell damage. Crit Care Med 2011 1.47
12 Vitamin C: a concentration-function approach yields pharmacology and therapeutic discoveries. Adv Nutr 2011 1.45
13 Influence of early antioxidant supplements on clinical evolution and organ function in critically ill cardiac surgery, major trauma, and subarachnoid hemorrhage patients. Crit Care 2008 1.34
14 Post cardiac arrest syndrome: a review of therapeutic strategies. Circulation 2011 1.26
15 Plasma concentrations of cytokines, their soluble receptors, and antioxidant vitamins can predict the development of multiple organ failure in patients at risk. Crit Care Med 1996 1.19
16 Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis. J Transl Med 2014 1.17
17 Postischemic renal oxidative stress induces inflammatory response through PAF and oxidized phospholipids. Prevention by antioxidant treatment. FASEB J 2002 1.10
18 A pilot clinical study of continuous intravenous ascorbate in terminal cancer patients. P R Health Sci J 2005 1.08
19 Leucocyte ascorbic acid levels after acute myocardial infarction. Br Heart J 1972 1.08
20 Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetics of high-dose intravenous ascorbic acid in patients with advanced cancer. Cancer Chemother Pharmacol 2013 1.07
21 Ascorbic acid dynamics in the seriously ill and injured. J Surg Res 2003 1.07
22 Vitamin C revisited. Crit Care 2014 1.01
23 Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells. J Cardiovasc Pharmacol 2001 0.94
24 Ascorbate-dependent vasopressor synthesis: a rationale for vitamin C administration in severe sepsis and septic shock? Crit Care 2015 0.93
25 Nitric oxide mediates tightening of the endothelial barrier by ascorbic acid. Biochem Biophys Res Commun 2010 0.89
26 EuReCa ONE - ONE month - ONE Europe - ONE goal. Resuscitation 2014 0.83
27 Protective effect of low dose of ascorbic acid on hepatobiliary function in hepatic ischemia/reperfusion in rats. J Hepatol 2002 0.82
28 The effect of vitamin C on ischemia reperfusion injury because of prolonged tourniquet application with reperfusion intervals. Ann Plast Surg 2009 0.78
29 Combination of intravenous ascorbic acid administration and hypothermia after resuscitation improves myocardial function and survival in a ventricular fibrillation cardiac arrest model in the rat. Acad Emerg Med 2014 0.78
30 Hydrocortisone, Vitamin C and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study. Chest 2016 0.77
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