|
1
|
A test of enhancing model accuracy in high-throughput crystallography.
|
2005
|
5.96
|
|
2
|
Autofix for backward-fit sidechains: using MolProbity and real-space refinement to put misfits in their place.
|
2008
|
4.60
|
|
3
|
Calmodulin target database.
|
2000
|
3.20
|
|
4
|
The evolutionary demography of duplicate genes.
|
2003
|
2.87
|
|
5
|
SUMO fusions and SUMO-specific protease for efficient expression and purification of proteins.
|
2004
|
2.71
|
|
6
|
Project management system for structural and functional proteomics: Sesame.
|
2003
|
2.19
|
|
7
|
Automation of protein purification for structural genomics.
|
2004
|
2.17
|
|
8
|
Preparation of Escherichia coli cell extract for highly productive cell-free protein expression.
|
2004
|
2.14
|
|
9
|
The Protein Model Portal.
|
2008
|
2.01
|
|
10
|
RIKEN structural genomics beamlines at the SPring-8; high throughput protein crystallography with automated beamline operation.
|
2006
|
1.85
|
|
11
|
Identification of protein functions from a molecular surface database, eF-site.
|
2002
|
1.79
|
|
12
|
Structural genomics of highly conserved microbial genes of unknown function in search of new antibacterial targets.
|
2003
|
1.70
|
|
13
|
The Scottish Structural Proteomics Facility: targets, methods and outputs.
|
2010
|
1.66
|
|
14
|
High-throughput purification and quality assurance of Arabidopsis thaliana proteins for eukaryotic structural genomics.
|
2005
|
1.65
|
|
15
|
Results from high-throughput DNA cloning of Arabidopsis thaliana target genes using site-specific recombination.
|
2005
|
1.64
|
|
16
|
Maximum likelihood methods for detecting adaptive evolution after gene duplication.
|
2003
|
1.61
|
|
17
|
Integration of genomic datasets to predict protein complexes in yeast.
|
2002
|
1.58
|
|
18
|
From protein structure to biochemical function?
|
2003
|
1.54
|
|
19
|
phenix.mr_rosetta: molecular replacement and model rebuilding with Phenix and Rosetta.
|
2012
|
1.53
|
|
20
|
Structural genomics is the largest contributor of novel structural leverage.
|
2009
|
1.52
|
|
21
|
Accurate and scalable identification of functional sites by evolutionary tracing.
|
2003
|
1.44
|
|
22
|
Structural genomics of protein phosphatases.
|
2007
|
1.40
|
|
23
|
Investigating ancient duplication events in the Arabidopsis genome.
|
2003
|
1.38
|
|
24
|
High-throughput limited proteolysis/mass spectrometry for protein domain elucidation.
|
2005
|
1.36
|
|
25
|
The Structural Biology Knowledgebase: a portal to protein structures, sequences, functions, and methods.
|
2011
|
1.36
|
|
26
|
Are all fishes ancient polyploids?
|
2003
|
1.32
|
|
27
|
His tag effect on solubility of human proteins produced in Escherichia coli: a comparison between four expression vectors.
|
2004
|
1.31
|
|
28
|
Characterization of proteins with wide-angle X-ray solution scattering (WAXS).
|
2010
|
1.30
|
|
29
|
Heterologous expression of L. major proteins in S. cerevisiae: a test of solubility, purity, and gene recoding.
|
2009
|
1.28
|
|
30
|
Protein crystallization analysis on the World Community Grid.
|
2010
|
1.27
|
|
31
|
PSI:Biology-materials repository: a biologist's resource for protein expression plasmids.
|
2011
|
1.26
|
|
32
|
More genes in vertebrates?
|
2003
|
1.24
|
|
33
|
High-throughput production of prokaryotic membrane proteins.
|
2005
|
1.24
|
|
34
|
SAD phasing using iodide ions in a high-throughput structural genomics environment.
|
2011
|
1.23
|
|
35
|
Introns in, introns out in plant gene families: a genomic approach of the dynamics of gene structure.
|
2003
|
1.21
|
|
36
|
Improved scoring function for comparative modeling using the M4T method.
|
2008
|
1.19
|
|
37
|
Numerous groups of chromosomal regional paralogies strongly indicate two genome doublings at the root of the vertebrates.
|
2003
|
1.18
|
|
38
|
Recent advances in GFP folding reporter and split-GFP solubility reporter technologies. Application to improving the folding and solubility of recalcitrant proteins from Mycobacterium tuberculosis.
|
2005
|
1.18
|
|
39
|
Functional evolution in the ancestral lineage of vertebrates or when genomic complexity was wagging its morphological tail.
|
2003
|
1.18
|
|
40
|
Automatic classification and pattern discovery in high-throughput protein crystallization trials.
|
2005
|
1.17
|
|
41
|
Selenomethionine incorporation into a protein by cell-free synthesis.
|
2002
|
1.17
|
|
42
|
Detection of gene duplications and block duplications in eukaryotic genomes.
|
2003
|
1.17
|
|
43
|
Large-scale transient transfection of mammalian cells: a newly emerging attractive option for recombinant protein production.
|
2005
|
1.16
|
|
44
|
Structural genomics of minimal organisms and protein fold space.
|
2005
|
1.16
|
|
45
|
Production of selenomethionine-labeled proteins in two-liter plastic bottles for structure determination.
|
2004
|
1.15
|
|
46
|
On-column protein refolding for crystallization.
|
2005
|
1.15
|
|
47
|
Structural genomics target selection for the New York consortium on membrane protein structure.
|
2009
|
1.14
|
|
48
|
Influence of the completeness of chemical shift assignments on NMR structures obtained with automated NOE assignment.
|
2003
|
1.14
|
|
49
|
Towards miniaturization of a structural genomics pipeline using micro-expression and microcoil NMR.
|
2005
|
1.13
|
|
50
|
A scaleable and integrated crystallization pipeline applied to mining the Thermotoga maritima proteome.
|
2004
|
1.13
|