Published in Curr Opin Cell Biol on February 01, 1999
Dynactin is required for microtubule anchoring at centrosomes. J Cell Biol (1999) 4.19
Regulators of the cytoplasmic dynein motor. Nat Rev Mol Cell Biol (2009) 4.05
Dynactin is required for bidirectional organelle transport. J Cell Biol (2003) 3.04
Functional coordination of three mitotic motors in Drosophila embryos. Mol Biol Cell (2000) 2.88
EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability. J Cell Biol (2000) 2.76
Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration. Nat Rev Neurosci (2012) 2.68
AAA+ Ring and linker swing mechanism in the dynein motor. Cell (2009) 2.63
Function of dynein and dynactin in herpes simplex virus capsid transport. Mol Biol Cell (2002) 2.61
Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin. J Cell Biol (2007) 2.52
Direct interaction of pericentrin with cytoplasmic dynein light intermediate chain contributes to mitotic spindle organization. J Cell Biol (1999) 2.49
Lis1 acts as a "clutch" between the ATPase and microtubule-binding domains of the dynein motor. Cell (2012) 2.48
Dynein/dynactin regulate metaphase spindle length by targeting depolymerizing activities to spindle poles. J Cell Biol (2004) 2.46
Genetic analysis of the cytoplasmic dynein subunit families. PLoS Genet (2006) 2.35
Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes. EMBO J (2001) 2.34
Cytoplasmic dynein-mediated assembly of pericentrin and gamma tubulin onto centrosomes. Mol Biol Cell (2000) 2.30
Sunday Driver links axonal transport to damage signaling. J Cell Biol (2005) 2.29
Microtubule binding by dynactin is required for microtubule organization but not cargo transport. J Cell Biol (2007) 2.17
Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization. J Cell Biol (2004) 2.12
Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry. PLoS Biol (2010) 2.07
Analysis of the dynein-dynactin interaction in vitro and in vivo. Mol Biol Cell (2003) 2.04
Regulation of the processivity and intracellular localization of Saccharomyces cerevisiae dynein by dynactin. Proc Natl Acad Sci U S A (2009) 1.99
Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control. Mol Biol Cell (2005) 1.98
3D structure of eukaryotic flagella in a quiescent state revealed by cryo-electron tomography. Proc Natl Acad Sci U S A (2005) 1.83
Retrograde axonal transport of herpes simplex virus: evidence for a single mechanism and a role for tegument. Proc Natl Acad Sci U S A (2000) 1.81
Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes. Blood (2005) 1.76
ATP-driven remodeling of the linker domain in the dynein motor. Structure (2012) 1.74
Distinct cell cycle-dependent roles for dynactin and dynein at centrosomes. J Cell Biol (2002) 1.70
Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment. Mol Biol Cell (2007) 1.67
Microtubules remodel actomyosin networks in Xenopus egg extracts via two mechanisms of F-actin transport. J Cell Biol (2000) 1.67
Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport. EMBO J (2003) 1.65
The 2.8 Å crystal structure of the dynein motor domain. Nature (2012) 1.65
Human Nudel and NudE as regulators of cytoplasmic dynein in poleward protein transport along the mitotic spindle. Mol Cell Biol (2003) 1.61
Nudel contributes to microtubule anchoring at the mother centriole and is involved in both dynein-dependent and -independent centrosomal protein assembly. Mol Biol Cell (2005) 1.58
Cortical Num1p interacts with the dynein intermediate chain Pac11p and cytoplasmic microtubules in budding yeast. J Cell Biol (2001) 1.51
Nudel functions in membrane traffic mainly through association with Lis1 and cytoplasmic dynein. J Cell Biol (2004) 1.47
The coordination of cyclic microtubule association/dissociation and tail swing of cytoplasmic dynein. Proc Natl Acad Sci U S A (2007) 1.46
The third P-loop domain in cytoplasmic dynein heavy chain is essential for dynein motor function and ATP-sensitive microtubule binding. Mol Biol Cell (2003) 1.44
Modulation of substrate adhesion dynamics via microtubule targeting requires kinesin-1. J Cell Biol (2002) 1.42
Mitochondrial transport and docking in axons. Exp Neurol (2009) 1.41
Specific chlamydial inclusion membrane proteins associate with active Src family kinases in microdomains that interact with the host microtubule network. Cell Microbiol (2010) 1.40
MHC class II molecules on the move for successful antigen presentation. EMBO J (2007) 1.38
Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles. Cell (2011) 1.38
The G59S mutation in p150(glued) causes dysfunction of dynactin in mice. J Neurosci (2007) 1.36
Spindly/CCDC99 is required for efficient chromosome congression and mitotic checkpoint regulation. Mol Biol Cell (2010) 1.33
The 14-kDa dynein light chain-family protein Dlc1 is required for regular oscillatory nuclear movement and efficient recombination during meiotic prophase in fission yeast. Mol Biol Cell (2002) 1.32
Antagonistic forces generated by myosin II and cytoplasmic dynein regulate microtubule turnover, movement, and organization in interphase cells. Proc Natl Acad Sci U S A (2001) 1.32
Motor number controls cargo switching at actin-microtubule intersections in vitro. Curr Biol (2010) 1.30
The interaction of neurofilaments with the microtubule motor cytoplasmic dynein. Mol Biol Cell (2004) 1.30
Identification of a novel light intermediate chain (D2LIC) for mammalian cytoplasmic dynein 2. Mol Biol Cell (2002) 1.29
A role for RIC-8 (Synembryn) and GOA-1 (G(o)alpha) in regulating a subset of centrosome movements during early embryogenesis in Caenorhabditis elegans. Genetics (2000) 1.28
Dynamic recruitment of Nek2 kinase to the centrosome involves microtubules, PCM-1, and localized proteasomal degradation. Mol Biol Cell (2005) 1.28
Transcription factor NF-kappaB is transported to the nucleus via cytoplasmic dynein/dynactin motor complex in hippocampal neurons. PLoS One (2007) 1.26
Subunit organization in cytoplasmic dynein subcomplexes. Protein Sci (2002) 1.24
Neuronal cotransport of glycine receptor and the scaffold protein gephyrin. J Cell Biol (2006) 1.22
Transcriptome analysis of functional differentiation between haploid and diploid cells of Emiliania huxleyi, a globally significant photosynthetic calcifying cell. Genome Biol (2009) 1.22
Transcriptional modulation of genes encoding structural characteristics of differentiating enterocytes during development of a polarized epithelium in vitro. Mol Biol Cell (2007) 1.22
Dynactin's pointed-end complex is a cargo-targeting module. Mol Biol Cell (2012) 1.20
LIN-5 is a novel component of the spindle apparatus required for chromosome segregation and cleavage plane specification in Caenorhabditis elegans. J Cell Biol (2000) 1.17
The microtubule plus-end localization of Aspergillus dynein is important for dynein-early-endosome interaction but not for dynein ATPase activation. J Cell Sci (2010) 1.17
Dynamic behavior of microtubules during dynein-dependent nuclear migrations of meiotic prophase in fission yeast. Mol Biol Cell (2001) 1.16
Insights into the micromechanical properties of the metaphase spindle. Cell (2011) 1.15
Systematic dissection of dynein regulators in mitosis. J Cell Biol (2013) 1.15
Intracellular transport of hepatitis B virus. World J Gastroenterol (2007) 1.14
Two modes of microtubule sliding driven by cytoplasmic dynein. Proc Natl Acad Sci U S A (2006) 1.13
The gene for the intermediate chain subunit of cytoplasmic dynein is essential in Drosophila. Genetics (2002) 1.11
Nucleoporin translocated promoter region (Tpr) associates with dynein complex, preventing chromosome lagging formation during mitosis. J Biol Chem (2010) 1.10
A mammalian NudC-like protein essential for dynein stability and cell viability. Proc Natl Acad Sci U S A (2006) 1.09
CLIP-170 homologue and NUDE play overlapping roles in NUDF localization in Aspergillus nidulans. Mol Biol Cell (2006) 1.09
Comparative genome analysis reveals a conserved family of actin-like proteins in apicomplexan parasites. BMC Genomics (2005) 1.08
Aurora A contributes to p150(glued) phosphorylation and function during mitosis. J Cell Biol (2010) 1.08
Null mutants of the neurospora actin-related protein 1 pointed-end complex show distinct phenotypes. Mol Biol Cell (2001) 1.06
Regulation of axonal mitochondrial transport and its impact on synaptic transmission. Neurosci Res (2011) 1.06
Snapin recruits dynein to BDNF-TrkB signaling endosomes for retrograde axonal transport and is essential for dendrite growth of cortical neurons. Cell Rep (2012) 1.06
The endocytic adaptor protein ARH associates with motor and centrosomal proteins and is involved in centrosome assembly and cytokinesis. Mol Biol Cell (2008) 1.06
Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde axonal transport. J Neurosci (2012) 1.06
Miro-1 links mitochondria and microtubule Dynein motors to control lymphocyte migration and polarity. Mol Cell Biol (2014) 1.04
SOCS-1 localizes to the microtubule organizing complex-associated 20S proteasome. Mol Cell Biol (2004) 1.04
The Drosophila tctex-1 light chain is dispensable for essential cytoplasmic dynein functions but is required during spermatid differentiation. Mol Biol Cell (2004) 1.02
Cytoplasmic dynein could be key to understanding neurodegeneration. Genome Biol (2008) 1.02
Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila. Mol Biol Cell (2012) 1.00
Analysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development. Neural Dev (2010) 1.00
Dynein-mediated pulling forces drive rapid mitotic spindle elongation in Ustilago maydis. EMBO J (2006) 0.98
A molecular genetic analysis of the interaction between the cytoplasmic dynein intermediate chain and the glued (dynactin) complex. Mol Biol Cell (2000) 0.97
Hook2 contributes to aggresome formation. BMC Cell Biol (2007) 0.96
Dynactin-membrane interaction is regulated by the C-terminal domains of p150(Glued). EMBO Rep (2001) 0.96
PLAC-24 is a cytoplasmic dynein-binding protein that is recruited to sites of cell-cell contact. Mol Biol Cell (2002) 0.95
The dynactin complex enhances the speed of microtubule-dependent motions of adenovirus both towards and away from the nucleus. Viruses (2011) 0.94
Dynein and dynactin leverage their bivalent character to form a high-affinity interaction. PLoS One (2013) 0.94
In vivo cell biology in zebrafish - providing insights into vertebrate development and disease. J Cell Sci (2014) 0.93
LIS1 at the microtubule plus end and its role in dynein-mediated nuclear migration. J Cell Biol (2003) 0.93
Molecular motors: directing traffic during RNA localization. Crit Rev Biochem Mol Biol (2011) 0.93
Apoptotic cleavage of cytoplasmic dynein intermediate chain and p150(Glued) stops dynein-dependent membrane motility. J Cell Biol (2001) 0.92
The dynein inhibitor Ciliobrevin D inhibits the bidirectional transport of organelles along sensory axons and impairs NGF-mediated regulation of growth cones and axon branches. Dev Neurobiol (2014) 0.92
Arp10p is a pointed-end-associated component of yeast dynactin. Mol Biol Cell (2005) 0.91
Expanding knowledge of P3 proteins in the poliovirus lifecycle. Future Microbiol (2010) 0.90
Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis. J Biol Chem (2012) 0.90
Human enhancer of invasion-cluster, a coiled-coil protein required for passage through mitosis. Mol Cell Biol (2004) 0.89
Transcriptome analyses of inhibitor-treated schistosome females provide evidence for cooperating Src-kinase and TGFβ receptor pathways controlling mitosis and eggshell formation. PLoS Pathog (2013) 0.89
A Ras-like domain in the light intermediate chain bridges the dynein motor to a cargo-binding region. Elife (2014) 0.89
Dynein-dependent motility of microtubules and nucleation sites supports polarization of the tubulin array in the fungus Ustilago maydis. Mol Biol Cell (2006) 0.88
Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex. J Biol Chem (1995) 3.96
The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1). Proc Natl Acad Sci U S A (1995) 3.77
Dynein binds to beta-catenin and may tether microtubules at adherens junctions. Nat Cell Biol (2001) 3.06
Characterization of a 50-kDa polypeptide in cytoplasmic dynein preparations reveals a complex with p150GLUED and a novel actin. J Biol Chem (1993) 2.91
Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles. J Cell Biol (1996) 2.41
Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin. Hum Mol Genet (1997) 2.28
The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport. Proc Natl Acad Sci U S A (1997) 2.26
beta III spectrin binds to the Arp1 subunit of dynactin. J Biol Chem (2001) 2.05
Dynactin-dependent, dynein-driven vesicle transport in the absence of membrane proteins: a role for spectrin and acidic phospholipids. Mol Cell (2001) 1.89
The role of the dynactin complex in intracellular motility. Int Rev Cytol (1998) 1.75
Functionally distinct isoforms of dynactin are expressed in human neurons. Mol Biol Cell (1996) 1.57
The involvement of the intermediate chain of cytoplasmic dynein in binding the motor complex to membranous organelles of Xenopus oocytes. Mol Biol Cell (1997) 1.56
The product of the Drosophila gene, Glued, is the functional homologue of the p150Glued component of the vertebrate dynactin complex. J Biol Chem (1996) 1.31
Characterization of the p22 subunit of dynactin reveals the localization of cytoplasmic dynein and dynactin to the midbody of dividing cells. J Cell Biol (1998) 1.27
Functional analysis of dynactin and cytoplasmic dynein in slow axonal transport. J Neurosci (1996) 1.23
Multiple mouse chromosomal loci for dynein-based motility. Genomics (1996) 1.13
Mutational analysis of motor proteins. Annu Rev Physiol (1996) 1.06
Expression of the p150Glued component of the dynactin complex in developing and adult rat brain. J Comp Neurol (1995) 1.03
Beta-centractin: characterization and distribution of a new member of the centractin family of actin-related proteins. Mol Biol Cell (1994) 1.01
Speculating about spectrin: new insights into the Golgi-associated cytoskeleton. Trends Cell Biol (1998) 1.00
A dynactin subunit with a highly conserved cysteine-rich motif interacts directly with Arp1. J Biol Chem (2000) 0.97
Casein kinase II binds to and phosphorylates cytoplasmic dynein. J Biol Chem (1997) 0.92
Subcellular targeting of the retrograde motor cytoplasmic dynein. Biochem Soc Trans (1995) 0.90
Dynactin phosphorylation is modulated in response to cellular effectors. Biochem Biophys Res Commun (1997) 0.84
Rate of ATP synthesis by dynein. Biochemistry (1986) 0.83
The genomic structure of DCTN1, a candidate gene for limb-girdle muscular dystrophy (LGMD2B). Biochim Biophys Acta (1998) 0.82
Dynein structure and function. J Cell Sci Suppl (1986) 0.81
Immunoselection and characterization of cDNA clones. Methods Cell Biol (1993) 0.80
Mouse p150Glued (dynactin 1) cDNA sequence and evaluation as a candidate for the neuromuscular disease mutation mnd2. Biochem Biophys Res Commun (1997) 0.77
Kinetic evidence for multiple dynein heads: modeling the dissociation reaction. J Biol Chem (1983) 0.75
Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued. Nature (1992) 0.75