Published in Mol Biol Cell on October 01, 1997
Dynactin is required for microtubule anchoring at centrosomes. J Cell Biol (1999) 4.19
Dynactin is required for bidirectional organelle transport. J Cell Biol (2003) 3.04
The herpes simplex virus 1 U(L)34 protein interacts with a cytoplasmic dynein intermediate chain and targets nuclear membrane. J Virol (2000) 2.43
In vitro formation of the endoplasmic reticulum occurs independently of microtubules by a controlled fusion reaction. J Cell Biol (2000) 2.38
Genetic analysis of the cytoplasmic dynein subunit families. PLoS Genet (2006) 2.35
Cytoplasmic dynein-mediated assembly of pericentrin and gamma tubulin onto centrosomes. Mol Biol Cell (2000) 2.30
Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the arp1 minifilament pointed end. J Cell Biol (1999) 2.06
Analysis of the dynein-dynactin interaction in vitro and in vivo. Mol Biol Cell (2003) 2.04
The axonal transport of mitochondria. J Cell Sci (2012) 1.88
The cortical protein Num1p is essential for dynein-dependent interactions of microtubules with the cortex. J Cell Biol (2000) 1.87
Accumulation of cytoplasmic dynein and dynactin at microtubule plus ends in Aspergillus nidulans is kinesin dependent. Mol Biol Cell (2003) 1.85
Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport. EMBO J (2003) 1.65
The Mr 140,000 intermediate chain of Chlamydomonas flagellar inner arm dynein is a WD-repeat protein implicated in dynein arm anchoring. Mol Biol Cell (1998) 1.58
Bidirectional translocation of neurofilaments along microtubules mediated in part by dynein/dynactin. Mol Biol Cell (2000) 1.56
Regulation of melanosome movement in the cell cycle by reversible association with myosin V. J Cell Biol (1999) 1.50
Modulation of substrate adhesion dynamics via microtubule targeting requires kinesin-1. J Cell Biol (2002) 1.42
Cytoplasmic dynein regulation by subunit heterogeneity and its role in apical transport. J Cell Biol (2001) 1.37
Microtubule-based endoplasmic reticulum motility in Xenopus laevis: activation of membrane-associated kinesin during development. Mol Biol Cell (1999) 1.28
The Chlamydomonas IDA7 locus encodes a 140-kDa dynein intermediate chain required to assemble the I1 inner arm complex. Mol Biol Cell (1998) 1.28
The kinesin KIF1C and microtubule plus ends regulate podosome dynamics in macrophages. Mol Biol Cell (2006) 1.27
Cytoplasmic dynein intermediate-chain isoforms with different targeting properties created by tissue-specific alternative splicing. Mol Cell Biol (1998) 1.27
Mutually exclusive cytoplasmic dynein regulation by NudE-Lis1 and dynactin. J Biol Chem (2011) 1.26
Dynein light intermediate chain: an essential subunit that contributes to spindle checkpoint inactivation. Mol Biol Cell (2008) 1.09
Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde axonal transport. J Neurosci (2012) 1.06
Cytoplasmic dynein-dynactin complex is required for spermatid growth but not axoneme assembly in Drosophila. Mol Biol Cell (2004) 0.99
A molecular genetic analysis of the interaction between the cytoplasmic dynein intermediate chain and the glued (dynactin) complex. Mol Biol Cell (2000) 0.97
Multiple mechanisms determine ER network morphology during the cell cycle in Xenopus egg extracts. J Cell Biol (2013) 0.95
PLAC-24 is a cytoplasmic dynein-binding protein that is recruited to sites of cell-cell contact. Mol Biol Cell (2002) 0.95
Evolution of the eukaryotic dynactin complex, the activator of cytoplasmic dynein. BMC Evol Biol (2012) 0.94
Lissencephaly-1 promotes the recruitment of dynein and dynactin to transported mRNAs. J Cell Biol (2013) 0.93
Apoptotic cleavage of cytoplasmic dynein intermediate chain and p150(Glued) stops dynein-dependent membrane motility. J Cell Biol (2001) 0.92
Three-dimensional reconstruction of the dynactin complex by single-particle image analysis. Proc Natl Acad Sci U S A (2005) 0.90
Misfolded Gβ is recruited to cytoplasmic dynein by Nudel for efficient clearance. Cell Res (2012) 0.84
Analyses of dynein heavy chain mutations reveal complex interactions between dynein motor domains and cellular dynein functions. Genetics (2012) 0.82
Microtubule assembly crucial to bovine embryonic development in assisted reproductive technologies. Anim Sci J (2016) 0.75
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A (1979) 365.71
Cell cycle extracts. Methods Cell Biol (1991) 9.47
Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis. J Cell Biol (1996) 7.65
Localization of cytoplasmic dynein to mitotic spindles and kinetochores. Nature (1990) 7.33
Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein. J Cell Biol (1991) 5.02
MAP 1C is a microtubule-activated ATPase which translocates microtubules in vitro and has dynein-like properties. J Cell Biol (1987) 4.78
Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued. J Cell Biol (1995) 4.66
Dynamic behavior of endoplasmic reticulum in living cells. Cell (1988) 4.59
Cytoplasmic dynein plays a role in mammalian mitotic spindle formation. J Cell Biol (1993) 4.43
Cytoplasmic dynein-dependent vesicular transport from early to late endosomes. J Cell Biol (1993) 4.12
Two activators of microtubule-based vesicle transport. J Cell Biol (1991) 4.06
Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex. J Biol Chem (1995) 3.96
The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1). Proc Natl Acad Sci U S A (1995) 3.77
Gliding movement of and bidirectional transport along single native microtubules from squid axoplasm: evidence for an active role of microtubules in cytoplasmic transport. J Cell Biol (1985) 3.58
The microtubule-dependent formation of a tubulovesicular network with characteristics of the ER from cultured cell extracts. Cell (1988) 3.34
Cytoplasmic dynein participates in the centrosomal localization of the Golgi complex. J Cell Biol (1992) 3.06
Video-enhanced contrast, differential interference contrast (AVEC-DIC) microscopy: a new method capable of analyzing microtubule-related motility in the reticulopodial network of Allogromia laticollaris. Cell Motil (1981) 2.80
Brain dynein (MAP1C) localizes on both anterogradely and retrogradely transported membranous organelles in vivo. J Cell Biol (1990) 2.76
Binding of myosin I to membrane lipids. Nature (1989) 2.76
Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles. J Cell Biol (1996) 2.41
Molecular motors are differentially distributed on Golgi membranes from polarized epithelial cells. J Cell Biol (1994) 2.26
The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport. Proc Natl Acad Sci U S A (1997) 2.26
The Mr 78,000 intermediate chain of Chlamydomonas outer arm dynein interacts with alpha-tubulin in situ. J Biol Chem (1991) 2.23
Molecular requirements for bi-directional movement of phagosomes along microtubules. J Cell Biol (1997) 2.13
Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles. J Cell Biol (1996) 2.10
Preparation of Fab fragments from IgGs of different animal species. Methods Enzymol (1980) 1.96
Cell cycle control of microtubule-based membrane transport and tubule formation in vitro. J Cell Biol (1991) 1.95
Kinectin, a major kinesin-binding protein on ER. J Cell Biol (1992) 1.87
Cell cycle regulation of dynein association with membranes modulates microtubule-based organelle transport. J Cell Biol (1996) 1.85
Binding of brush border myosin I to phospholipid vesicles. J Cell Biol (1990) 1.81
Formation of membrane networks in vitro by kinesin-driven microtubule movement. J Cell Biol (1988) 1.81
Homology of the 74-kD cytoplasmic dynein subunit with a flagellar dynein polypeptide suggests an intracellular targeting function. J Cell Biol (1992) 1.81
Video-enhanced microscopy with a computer frame memory. J Microsc (1983) 1.78
Localization and specificity of the phospholipid and actin binding sites on the tail of Acanthamoeba myosin IC. J Cell Biol (1992) 1.77
Immunolocalization of cytoplasmic dynein to lysosomes in cultured cells. J Cell Sci (1992) 1.72
Construction of the endoplasmic reticulum. J Cell Biol (1989) 1.60
Protein phosphatase 1 regulates the cytoplasmic dynein-driven formation of endoplasmic reticulum networks in vitro. J Cell Biol (1995) 1.58
Functionally distinct isoforms of dynactin are expressed in human neurons. Mol Biol Cell (1996) 1.57
Cytoplasmic dynein is a vesicle protein. J Biol Chem (1992) 1.44
Kinesin and cytoplasmic dynein binding to brain microsomes. J Biol Chem (1992) 1.33
Movement of membrane tubules along microtubules in vitro: evidence for specialised sites of motor attachment. J Cell Sci (1994) 1.31
Immunogold localisation of the intermediate chain within the protein complex of cytoplasmic dynein. J Struct Biol (1997) 1.20
Interactions among endoplasmic reticulum, microtubules, and retrograde movements of the cell surface. Cell Motil Cytoskeleton (1994) 1.20
Cytoplasmic microtubules linked to endoplasmic reticulum with cross-bridges. Exp Cell Res (1971) 1.19
Association of a cellular myosin II with anionic phospholipids and the neuronal plasma membrane. Proc Natl Acad Sci U S A (1994) 1.19
Plus-end motors override minus-end motors during transport of squid axon vesicles on microtubules. J Cell Biol (1996) 1.19
Microtubule-associated protein-dependent binding of phagosomes to microtubules. J Biol Chem (1996) 1.14
Cytoplasmic dynein binds to phospholipid vesicles. Cell Motil Cytoskeleton (1994) 1.12
Reversible assembly purification of taxol-treated microtubules. Methods Enzymol (1991) 0.85
Assay of membrane motility in interphase and metaphase Xenopus extracts. Methods Cell Biol (1993) 0.85
Use of colonoscopy to screen asymptomatic adults for colorectal cancer. Veterans Affairs Cooperative Study Group 380. N Engl J Med (2000) 13.21
One-time screening for colorectal cancer with combined fecal occult-blood testing and examination of the distal colon. N Engl J Med (2001) 8.76
Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis. J Cell Biol (1996) 7.65
Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. J Cell Biol (1997) 6.57
MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover. Cell (1999) 6.40
A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function. Nat Cell Biol (2000) 5.29
Retrograde transport by the microtubule-associated protein MAP 1C. Nature (1987) 5.06
Effects of mutant rat dynamin on endocytosis. J Cell Biol (1993) 5.05
A taxol-dependent procedure for the isolation of microtubules and microtubule-associated proteins (MAPs). J Cell Biol (1982) 4.94
MAP 1C is a microtubule-activated ATPase which translocates microtubules in vitro and has dynein-like properties. J Cell Biol (1987) 4.78
Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis. Nature (1991) 4.69
Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued. J Cell Biol (1995) 4.66
Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins. Nature (1990) 4.30
Identification of dynamin, a novel mechanochemical enzyme that mediates interactions between microtubules. Cell (1989) 3.97
Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex. J Biol Chem (1995) 3.96
Efficacy of carotid endarterectomy for asymptomatic carotid stenosis. The Veterans Affairs Cooperative Study Group. N Engl J Med (1993) 3.93
The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1). Proc Natl Acad Sci U S A (1995) 3.77
Cytoplasmic dynein and dynactin in cell division and intracellular transport. Curr Opin Cell Biol (1999) 3.63
Gliding movement of and bidirectional transport along single native microtubules from squid axoplasm: evidence for an active role of microtubules in cytoplasmic transport. J Cell Biol (1985) 3.58
Actin-dependent organelle movement in squid axoplasm. Nature (1992) 3.51
Bone formation in vivo: comparison of osteogenesis by transplanted mouse and human marrow stromal fibroblasts. Transplantation (1997) 3.40
DYNEINS: molecular structure and cellular function. Annu Rev Cell Biol (1994) 3.26
Microtubule- and motor-dependent fusion in vitro between apical and basolateral endocytic vesicles from MDCK cells. Cell (1990) 3.07
Dynein binds to beta-catenin and may tether microtubules at adherens junctions. Nat Cell Biol (2001) 3.06
Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued. Nature (1991) 2.99
An extended microtubule-binding structure within the dynein motor domain. Nature (1997) 2.93
Characterization of a 50-kDa polypeptide in cytoplasmic dynein preparations reveals a complex with p150GLUED and a novel actin. J Biol Chem (1993) 2.91
Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization. Curr Biol (2001) 2.89
Bovine brain kinesin is a microtubule-activated ATPase. Proc Natl Acad Sci U S A (1986) 2.80
Mutations in the tail domain of DYNC1H1 cause dominant spinal muscular atrophy. Neurology (2012) 2.56
DNM1, a dynamin-related gene, participates in endosomal trafficking in yeast. J Cell Biol (1995) 2.46
Dynamin is a GTPase stimulated to high levels of activity by microtubules. Nature (1992) 2.45
The herpes simplex virus 1 U(L)34 protein interacts with a cytoplasmic dynein intermediate chain and targets nuclear membrane. J Virol (2000) 2.43
Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles. J Cell Biol (1996) 2.41
Interaction of brain cytoplasmic dynein and MAP2 with a common sequence at the C terminus of tubulin. Nature (1989) 2.41
Widespread distribution of the major polypeptide component of MAP 1 (microtubule-associated protein 1) in the nervous system. J Cell Biol (1984) 2.38
The non-tubulin component of microtubule protein oligomers. Effect on self-association and hydrodynamic properties. J Biol Chem (1978) 2.36
Colocalization of cytoplasmic dynein with dynactin and CLIP-170 at microtubule distal ends. J Cell Sci (1999) 2.32
Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin. Hum Mol Genet (1997) 2.28
The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport. Proc Natl Acad Sci U S A (1997) 2.26
Molecular cloning of the retrograde transport motor cytoplasmic dynein (MAP 1C). Neuron (1993) 2.24
Reproduction of human fibrous dysplasia of bone in immunocompromised mice by transplanted mosaics of normal and Gsalpha-mutated skeletal progenitor cells. J Clin Invest (1998) 2.20
From research to national expansion: 20 years' experience of community-based management of childhood pneumonia in Nepal. Bull World Health Organ (2008) 2.20
Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome. Mol Biol Cell (2002) 2.12
Identity and polymerization-stimulatory activity of the nontubulin proteins associated with microtubules. Biochemistry (1977) 2.07
beta III spectrin binds to the Arp1 subunit of dynactin. J Biol Chem (2001) 2.05
Distribution of microtubule-associated protein 2 in the nervous system of the rat studied by immunofluorescence. Neuroscience (1984) 2.04
Widespread cellular distribution of MAP-1A (microtubule-associated protein 1A) in the mitotic spindle and on interphase microtubules. J Cell Biol (1984) 2.03
Molecular characterization of the cAMP-dependent protein kinase bound to microtubule-associated protein 2. J Biol Chem (1982) 2.01
The major myosin-binding domain of skeletal muscle MyBP-C (C protein) resides in the COOH-terminal, immunoglobulin C2 motif. J Cell Biol (1993) 1.97
A protein kinase bound to the projection portion of MAP 2 (microtubule-associated protein 2). J Cell Biol (1981) 1.97
Association of microtubule-associated protein 2 (MAP 2) with microtubules and intermediate filaments in cultured brain cells. J Cell Biol (1983) 1.93
Low molecular weight microtubule-associated proteins are light chains of microtubule-associated protein 1 (MAP 1). Proc Natl Acad Sci U S A (1983) 1.90
Dynactin-dependent, dynein-driven vesicle transport in the absence of membrane proteins: a role for spectrin and acidic phospholipids. Mol Cell (2001) 1.89
Microtubules and Src homology 3 domains stimulate the dynamin GTPase via its C-terminal domain. Proc Natl Acad Sci U S A (1993) 1.88
Preparation of microtubules from rat liver and testis: cytoplasmic dynein is a major microtubule associated protein. Cell Motil Cytoskeleton (1989) 1.83
Light intermediate chain 1 defines a functional subfraction of cytoplasmic dynein which binds to pericentrin. J Biol Chem (2000) 1.82
Reversible assembly purification of microtubules without assembly-promoting agents and further purification of tubulin, microtubule-associated proteins, and MAP fragments. Methods Enzymol (1986) 1.82
Homology of the 74-kD cytoplasmic dynein subunit with a flagellar dynein polypeptide suggests an intracellular targeting function. J Cell Biol (1992) 1.81
Cytoplasmic dynein and dynactin are required for the transport of microtubules into the axon. J Cell Biol (1998) 1.80
The role of the dynactin complex in intracellular motility. Int Rev Cytol (1998) 1.75
Cytoplasmic dynein intermediate chain phosphorylation regulates binding to dynactin. J Biol Chem (2001) 1.74
Microtubule-associated protein 1B: identification of a major component of the neuronal cytoskeleton. Proc Natl Acad Sci U S A (1985) 1.72
Transport of ER vesicles on actin filaments in neurons by myosin V. J Cell Sci (1998) 1.71
Bone marrow stromal cells: characterization and clinical application. Crit Rev Oral Biol Med (1999) 1.70
Distinct but overlapping sites within the cytoplasmic dynein heavy chain for dimerization and for intermediate chain and light intermediate chain binding. J Biol Chem (2000) 1.69
Liquid level sensor using ultrasonic Lamb waves. Ultrasonics (2003) 1.66
Mutations of the GNAS1 gene, stromal cell dysfunction, and osteomalacic changes in non-McCune-Albright fibrous dysplasia of bone. J Bone Miner Res (2000) 1.65
Removal of the projections from cytoplasmic microtubules in vitro by digestion with trypsin. J Biol Chem (1977) 1.65
Repair of craniotomy defects using bone marrow stromal cells. Transplantation (1998) 1.60
Functionally distinct isoforms of dynactin are expressed in human neurons. Mol Biol Cell (1996) 1.57
Isolation of sea urchin egg microtubules with taxol and identification of mitotic spindle microtubule-associated proteins with monoclonal antibodies. Proc Natl Acad Sci U S A (1983) 1.55
Characterization of the microtubule-activated ATPase of brain cytoplasmic dynein (MAP 1C). J Cell Biol (1988) 1.51
MAP 1A and MAP 1B are structurally related microtubule associated proteins with distinct developmental patterns in the CNS. J Neurosci (1989) 1.48
Use of disulfiram for alcoholics in methadone maintenance programs. A Veterans Administration Cooperative Study. Arch Gen Psychiatry (1983) 1.47
A binding site for SH3 domains targets dynamin to coated pits. J Biol Chem (1996) 1.42
Multiple distinct coiled-coils are involved in dynamin self-assembly. J Biol Chem (1999) 1.41
Frozen tissue sections as an experimental system to reveal specific binding sites for the regulatory subunit of type II cAMP-dependent protein kinase in neurons. Proc Natl Acad Sci U S A (1982) 1.40
Purification of microtubules and microtubule-associated proteins from sea urchin eggs and cultured mammalian cells using taxol, and use of exogenous taxol-stabilized brain microtubules for purifying microtubule-associated proteins. Methods Enzymol (1986) 1.38
Microtubule-associated protein MAP1 promotes microtubule assembly in vitro. FEBS Lett (1981) 1.36
Role of the basic, proline-rich region of dynamin in Src homology 3 domain binding and endocytosis. J Biol Chem (1997) 1.35
Differential expression and phosphorylation of the 74-kDa intermediate chains of cytoplasmic dynein in cultured neurons and glia. J Biol Chem (1996) 1.32
Isolated flagellar outer arm dynein translocates brain microtubules in vitro. Nature (1988) 1.32
The product of the Drosophila gene, Glued, is the functional homologue of the p150Glued component of the vertebrate dynactin complex. J Biol Chem (1996) 1.31
Microtubule movement by a biotinated kinesin bound to streptavidin-coated surface. J Biol Chem (1994) 1.29
Interaction of the p62 subunit of dynactin with Arp1 and the cortical actin cytoskeleton. Curr Biol (2000) 1.28
Opposing motor activities of dynein and kinesin determine retention and transport of MHC class II-containing compartments. J Cell Sci (1999) 1.28