Published in Mol Biol Cell on April 01, 1999
Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer. J Cell Biol (2004) 4.60
Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor. J Cell Biol (2004) 4.24
Retromer. Curr Opin Cell Biol (2008) 3.89
Specific retrieval of the exocytic SNARE Snc1p from early yeast endosomes. Mol Biol Cell (2000) 3.32
Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes. Mol Biol Cell (2000) 2.69
Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7. J Cell Biol (2008) 2.56
Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomes. EMBO J (2003) 2.29
Functional architecture of the retromer cargo-recognition complex. Nature (2007) 2.26
Vps52p, Vps53p, and Vps54p form a novel multisubunit complex required for protein sorting at the yeast late Golgi. Mol Biol Cell (2000) 2.14
Sorting of yeast membrane proteins into an endosome-to-Golgi pathway involves direct interaction of their cytosolic domains with Vps35p. J Cell Biol (2000) 2.11
The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain. Nat Struct Mol Biol (2006) 2.09
Retromer terminates the generation of cAMP by internalized PTH receptors. Nat Chem Biol (2011) 1.88
Grd19/Snx3p functions as a cargo-specific adapter for retromer-dependent endocytic recycling. J Cell Biol (2007) 1.65
Plant retromer, localized to the prevacuolar compartment and microvesicles in Arabidopsis, may interact with vacuolar sorting receptors. Plant Cell (2006) 1.54
SNX-BAR proteins in phosphoinositide-mediated, tubular-based endosomal sorting. Semin Cell Dev Biol (2009) 1.49
Vps26p, a component of retromer, directs the interactions of Vps35p in endosome-to-Golgi retrieval. Mol Biol Cell (2001) 1.47
Evolutionary reconstruction of the retromer complex and its function in Trypanosoma brucei. J Cell Sci (2011) 1.29
Genetic analysis of sorting nexins 1 and 2 reveals a redundant and essential function in mice. Mol Biol Cell (2002) 1.24
The yeast GRD20 gene is required for protein sorting in the trans-Golgi network/endosomal system and for polarization of the actin cytoskeleton. Mol Biol Cell (1999) 1.23
The Gcs1 and Age2 ArfGAP proteins provide overlapping essential function for transport from the yeast trans-Golgi network. J Cell Biol (2001) 1.22
Ric1p and the Ypt6p GTPase function in a common pathway required for localization of trans-Golgi network membrane proteins. Mol Biol Cell (2001) 1.18
The clathrin adaptor complex 1 directly binds to a sorting signal in Ste13p to reduce the rate of its trafficking to the late endosome of yeast. J Cell Biol (2006) 1.15
The human Vps29 retromer component is a metallo-phosphoesterase for a cation-independent mannose 6-phosphate receptor substrate peptide. Biochem J (2006) 1.09
The synaptojanin-like protein Inp53/Sjl3 functions with clathrin in a yeast TGN-to-endosome pathway distinct from the GGA protein-dependent pathway. Mol Biol Cell (2003) 1.08
Identification of a conserved motif required for Vps35p/Vps26p interaction and assembly of the retromer complex. Biochem J (2007) 1.05
Rab GTPase regulation of retromer-mediated cargo export during endosome maturation. Mol Biol Cell (2012) 1.05
VPS29 is not an active metallo-phosphatase but is a rigid scaffold required for retromer interaction with accessory proteins. PLoS One (2011) 0.99
A mechanism for retromer endosomal coat complex assembly with cargo. Proc Natl Acad Sci U S A (2013) 0.98
RME-8 coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation. J Cell Sci (2014) 0.98
Structural features of vps35p involved in interaction with other subunits of the retromer complex. Traffic (2007) 0.95
Evidence for Golgi bodies in proposed 'Golgi-lacking' lineages. Proc Biol Sci (2003) 0.91
Phosphoinositide 3-kinase regulates the role of retromer in transcytosis of the polymeric immunoglobulin receptor. Exp Cell Res (2006) 0.89
Retromer-Mediated Trafficking of Transmembrane Receptors and Transporters. Membranes (Basel) (2015) 0.88
Inhibition of retromer activity by herpesvirus saimiri tip leads to CD4 downregulation and efficient T cell transformation. J Virol (2011) 0.88
Loss-of-function mutations of retromer large subunit genes suppress the phenotype of an Arabidopsis zig mutant that lacks Qb-SNARE VTI11. Plant Cell (2010) 0.88
Sorting of the yeast vacuolar-type, proton-translocating ATPase enzyme complex (V-ATPase): identification of a necessary and sufficient Golgi/endosomal retention signal in Stv1p. J Biol Chem (2012) 0.88
Mechanisms governing the endosomal membrane recruitment of the core retromer in Arabidopsis. J Biol Chem (2013) 0.87
Golgi-to-late endosome trafficking of the yeast pheromone processing enzyme Ste13p is regulated by a phosphorylation site in its cytosolic domain. Mol Biol Cell (2005) 0.85
A novel mechanism for localizing membrane proteins to yeast trans-Golgi network requires function of synaptojanin-like protein. Mol Biol Cell (2001) 0.85
Vps10p cycles between the TGN and the late endosome via the plasma membrane in clathrin mutants. Mol Biol Cell (2002) 0.84
The yeast mutant vps5Delta affected in the recycling of Golgi membrane proteins displays an enhanced vacuolar Mg2+/H+ exchange activity. Proc Natl Acad Sci U S A (2001) 0.82
Biogenesis of endosome-derived transport carriers. Cell Mol Life Sci (2015) 0.82
Rab5-family guanine nucleotide exchange factors bind retromer and promote its recruitment to endosomes. Mol Biol Cell (2015) 0.79
Direct binding of the Kex2p cytosolic tail to the VHS domain of yeast Gga2p facilitates TGN to prevacuolar compartment transport and is regulated by phosphorylation. Mol Biol Cell (2013) 0.78
A CDC25 family protein phosphatase gates cargo recognition by the Vps26 retromer subunit. Elife (2017) 0.75
Vacuolar Protein Sorting Genes in Parkinson's Disease: A Re-appraisal of Mutations Detection Rate and Neurobiology of Disease. Front Neurosci (2016) 0.75
The Coordinated Action of Calcineurin and Cathepsin D Protects Against α-Synuclein Toxicity. Front Mol Neurosci (2017) 0.75
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics (1989) 105.30
Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol (1987) 66.52
A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol Gen Genet (1984) 35.54
A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene (1987) 19.68
Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol (1988) 13.27
Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants. Mol Biol Cell (1992) 9.63
Protein sorting by transport vesicles. Science (1996) 7.47
Randomization of genes by PCR mutagenesis. PCR Methods Appl (1992) 6.76
Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway. Cell (1986) 5.73
Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors. Annu Rev Biochem (1992) 5.64
Clathrin-coated vesicle formation and protein sorting: an integrated process. Annu Rev Biochem (1997) 5.58
Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase. EMBO J (1989) 5.12
The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene. Cell (1994) 5.10
VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae. J Cell Biol (1995) 5.04
Yeast Saccharomyces cerevisiae selectable markers in pUC18 polylinkers. Yeast (1990) 5.00
Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeast. Mol Biol Cell (1996) 4.58
Methods for studying the yeast vacuole. Methods Enzymol (1991) 4.55
Immunolocalization of Kex2 protease identifies a putative late Golgi compartment in the yeast Saccharomyces cerevisiae. J Cell Biol (1991) 4.54
Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface. EMBO J (1994) 4.46
A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast. J Cell Biol (1998) 4.41
Membrane protein sorting in the yeast secretory pathway: evidence that the vacuole may be the default compartment. J Cell Biol (1992) 4.20
Enzymes required for yeast prohormone processing. Annu Rev Physiol (1988) 4.06
PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization. Cell (1998) 3.79
Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products. J Cell Biol (1997) 3.61
Mutation of a tyrosine localization signal in the cytosolic tail of yeast Kex2 protease disrupts Golgi retention and results in default transport to the vacuole. Mol Biol Cell (1992) 3.49
Two syntaxin homologues in the TGN/endosomal system of yeast. EMBO J (1998) 3.48
Linking cargo to vesicle formation: receptor tail interactions with coat proteins. Curr Opin Cell Biol (1997) 3.44
The END3 gene encodes a protein that is required for the internalization step of endocytosis and for actin cytoskeleton organization in yeast. Mol Biol Cell (1994) 3.43
Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast. J Cell Biol (1994) 3.32
Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases. J Cell Biol (1996) 3.23
Intracellular movement of two mannose 6-phosphate receptors: return to the Golgi apparatus. J Cell Biol (1988) 3.05
Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network. J Cell Biol (1994) 2.95
COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast. Cell (1995) 2.87
TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking. Cell (1998) 2.76
Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin. EMBO J (1995) 2.76
The VPS1 protein, a homolog of dynamin required for vacuolar protein sorting in Saccharomyces cerevisiae, is a GTPase with two functionally separable domains. J Cell Biol (1992) 2.69
Golgi and vacuolar membrane proteins reach the vacuole in vps1 mutant yeast cells via the plasma membrane. J Cell Biol (1995) 2.65
Kin recognition between medial Golgi enzymes in HeLa cells. EMBO J (1994) 2.62
Novel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component. EMBO J (1997) 2.60
Retrieval of TGN proteins from the cell surface requires endosomal acidification. EMBO J (1994) 2.56
An acidic sequence within the cytoplasmic domain of furin functions as a determinant of trans-Golgi network localization and internalization from the cell surface. EMBO J (1995) 2.54
The cytoplasmic tail domain of the vacuolar protein sorting receptor Vps10p and a subset of VPS gene products regulate receptor stability, function, and localization. Mol Biol Cell (1995) 2.50
The yeast v-SNARE Vti1p mediates two vesicle transport pathways through interactions with the t-SNAREs Sed5p and Pep12p. J Cell Biol (1997) 2.50
Recycling of proteins from the Golgi compartment to the ER in yeast. J Cell Biol (1990) 2.38
Alternative pathways for the sorting of soluble vacuolar proteins in yeast: a vps35 null mutant missorts and secretes only a subset of vacuolar hydrolases. Mol Biol Cell (1992) 2.32
Sorting of membrane proteins in the secretory pathway. Cell (1993) 2.16
Membrane protein retention in the yeast Golgi apparatus: dipeptidyl aminopeptidase A is retained by a cytoplasmic signal containing aromatic residues. J Cell Biol (1993) 2.15
A sorting nexin-1 homologue, Vps5p, forms a complex with Vps17p and is required for recycling the vacuolar protein-sorting receptor. Mol Biol Cell (1997) 2.14
Characteristics of endoplasmic reticulum-derived transport vesicles. J Cell Biol (1994) 2.05
Tlg2p, a yeast syntaxin homolog that resides on the Golgi and endocytic structures. J Biol Chem (1998) 1.93
SOI1 encodes a novel, conserved protein that promotes TGN-endosomal cycling of Kex2p and other membrane proteins by modulating the function of two TGN localization signals. J Cell Biol (1997) 1.90
Oligomerization of a membrane protein correlates with its retention in the Golgi complex. J Cell Biol (1993) 1.85
The yeast VPS5/GRD2 gene encodes a sorting nexin-1-like protein required for localizing membrane proteins to the late Golgi. J Cell Sci (1997) 1.82
Localization of furin to the trans-Golgi network and recycling from the cell surface involves Ser and Tyr residues within the cytoplasmic domain. J Biol Chem (1995) 1.80
Two separate signals act independently to localize a yeast late Golgi membrane protein through a combination of retrieval and retention. J Cell Biol (1997) 1.74
The functioning of the yeast Golgi apparatus requires an ER protein encoded by ANP1, a member of a new family of genes affecting the secretory pathway. EMBO J (1994) 1.66
Yeast Kex1p is a Golgi-associated membrane protein: deletions in a cytoplasmic targeting domain result in mislocalization to the vacuolar membrane. J Cell Biol (1992) 1.66
The yeast VPS17 gene encodes a membrane-associated protein required for the sorting of soluble vacuolar hydrolases. J Biol Chem (1993) 1.58
The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins. Mol Cell Biol (1996) 1.54
Retrieval of resident late-Golgi membrane proteins from the prevacuolar compartment of Saccharomyces cerevisiae is dependent on the function of Grd19p. J Cell Biol (1998) 1.52
TGN38/41: a molecule on the move. Trends Cell Biol (1993) 1.06
Retrieval of HDEL proteins is required for growth of yeast cells. J Cell Biol (1994) 0.96