Asymptotic bias and efficiency in case-control studies of candidate genes and gene-environment interactions: basic family designs.

PubWeight™: 3.31‹?› | Rank: Top 1%

🔗 View Article (PMID 10206618)

Published in Am J Epidemiol on April 15, 1999

Authors

J S Witte1, W J Gauderman, D C Thomas

Author Affiliations

1: Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH 44109-1998, USA.

Articles citing this

Evaluation of candidate genes in case-control studies: a statistical method to account for related subjects. Am J Hum Genet (2001) 4.09

Recent developments in genomewide association scans: a workshop summary and review. Am J Hum Genet (2005) 3.76

Family-based tests of association in the presence of linkage. Am J Hum Genet (2000) 3.74

The use of case-parent triads to study joint effects of genotype and exposure. Am J Hum Genet (2000) 2.39

Methods for investigating gene-environment interactions in candidate pathway and genome-wide association studies. Annu Rev Public Health (2010) 1.88

Genome-wide association studies and beyond. Annu Rev Public Health (2010) 1.73

Bias and efficiency in family-based gene-characterization studies: conditional, prospective, retrospective, and joint likelihoods. Am J Hum Genet (2000) 1.62

Alpha1-antitrypsin deficiency carriers, tobacco smoke, chronic obstructive pulmonary disease, and lung cancer risk. Arch Intern Med (2008) 1.57

Gene-environment interaction tests for dichotomous traits in trios and sibships. Genet Epidemiol (2009) 1.43

A novel genetic polymorphism of inducible nitric oxide synthase is associated with an increased risk of gastric cancer. World J Gastroenterol (2004) 1.40

Challenges and opportunities in genome-wide environmental interaction (GWEI) studies. Hum Genet (2012) 1.37

Nitric oxide synthase genes and their interactions with environmental factors in Parkinson's disease. Neurogenetics (2008) 1.36

Gene-environment interactions in cancer epidemiology: a National Cancer Institute Think Tank report. Genet Epidemiol (2013) 1.27

Population-based, case-control-family design to investigate genetic and environmental influences on melanoma risk: Australian Melanoma Family Study. Am J Epidemiol (2009) 1.27

Integrating epidemiology and genetic association: the challenge of gene-environment interaction. Philos Trans R Soc Lond B Biol Sci (2005) 1.25

Assessment of Alzheimer's disease case-control associations using family-based methods. Neurogenetics (2008) 1.23

GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results. Arch Neurol (2009) 1.13

Detection of disease genes by use of family data. I. Likelihood-based theory. Am J Hum Genet (2000) 1.07

Genetic variation in the vitamin D receptor (VDR) and the vitamin D-binding protein (GC) and risk for colorectal cancer: results from the Colon Cancer Family Registry. Cancer Epidemiol Biomarkers Prev (2010) 1.07

Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registry. Cancer Epidemiol Biomarkers Prev (2010) 1.03

Association of GSK3B with Alzheimer disease and frontotemporal dementia. Arch Neurol (2008) 0.98

Familial Alzheimer disease in Latinos: interaction between APOE, stroke, and estrogen replacement. Neurology (2006) 0.98

IκBKβ and NFκB1, NSAID use and risk of colorectal cancer in the Colon Cancer Family Registry. Carcinogenesis (2012) 0.95

On combining family-based and population-based case-control data in association studies. Biometrics (2010) 0.93

COX-1 (PTGS1) and COX-2 (PTGS2) polymorphisms, NSAID interactions, and risk of colon and rectal cancers in two independent populations. Cancer Causes Control (2013) 0.92

Genes involved with folate uptake and distribution and their association with colorectal cancer risk. Cancer Causes Control (2009) 0.92

Tests for compositional epistasis under single interaction-parameter models. Ann Hum Genet (2010) 0.90

Family-based approaches: design, imputation, analysis, and beyond. BMC Genet (2016) 0.89

Psychiatric illness, socioeconomic status, and marital status in people committing suicide: a matched case-sibling-control study. J Epidemiol Community Health (2006) 0.88

Lack of replication of the GRIN2A-by-coffee interaction in Parkinson disease. PLoS Genet (2014) 0.86

Design and analysis issues in gene and environment studies. Environ Health (2012) 0.86

MC1R genotypes and risk of melanoma before age 40 years: a population-based case-control-family study. Int J Cancer (2012) 0.86

On combining triads and unrelated subjects data in candidate gene studies: an application to data on testicular cancer. Hum Hered (2008) 0.85

Interaction models of CYP1A1, GSTM1 polymorphisms and tobacco smoking in intestinal gastric cancer. World J Gastroenterol (2005) 0.85

Spouses and unrelated friends of probands as controls for stroke genetics studies. Neuroepidemiology (2003) 0.83

Semiparametric Bayesian modeling of random genetic effects in family-based association studies. Stat Med (2009) 0.83

Two-phase and family-based designs for next-generation sequencing studies. Front Genet (2013) 0.82

Genetic variations in SMAD7 are associated with colorectal cancer risk in the colon cancer family registry. PLoS One (2013) 0.81

Assessing effects of disease genes and gene-environment interactions: the case-spouse design and the counterfactual-control analysis. J Epidemiol Community Health (2006) 0.80

Gene-environment interactions in cardiovascular disease. Eur J Cardiovasc Nurs (2012) 0.79

A new family-based association test via a least-squares method. BMC Genet (2005) 0.78

Validity and power of association testing in family-based sampling designs: evidence for and against the common wisdom. Genet Epidemiol (2011) 0.77

Associations between NOS1AP single nucleotide polymorphisms (SNPs) and QT interval duration in four racial/ethnic groups in the Multi-Ethnic Study of Atherosclerosis (MESA). Ann Noninvasive Electrocardiol (2013) 0.77

Two-stage family-based designs for sequencing studies. BMC Proc (2014) 0.77

Re: "Asymptotic bias and efficiency in case-control studies of candidate genes and gene-environment interactions: basic family designs". Am J Epidemiol (2000) 0.77

Retrospective analysis of main and interaction effects in genetic association studies of human complex traits. BMC Genet (2007) 0.77

Combining disease models to test for gene-environment interaction in nuclear families. Biometrics (2011) 0.76

Gene × environment interaction models in psychiatric genetics. Curr Top Behav Neurosci (2012) 0.76

On the validity of within-nuclear-family genetic association analysis in samples of extended families. Stat Appl Genet Mol Biol (2015) 0.75

Detecting gene-environment interactions in human birth defects: Study designs and statistical methods. Birth Defects Res A Clin Mol Teratol (2015) 0.75

A permutation test for oligoset DNA pooling studies. PLoS One (2015) 0.75

Parent-child pair design for detecting gene-environment interactions in complex diseases. Hum Genet (2007) 0.75

Chronic PM2.5 exposure and risk of infant bronchiolitis and otitis media clinical encounters. Int J Hyg Environ Health (2017) 0.75

Articles by these authors

Mutation detection and single-molecule counting using isothermal rolling-circle amplification. Nat Genet (1998) 9.84

Haplotype sharing analysis using mantel statistics. Hum Hered (2005) 6.76

The problem of multiple inference in studies designed to generate hypotheses. Am J Epidemiol (1985) 4.76

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis. Cell (1996) 4.47

Community care of corneal ulcers. Am J Ophthalmol (1992) 3.77

A study of twelve Southern California communities with differing levels and types of air pollution. I. Prevalence of respiratory morbidity. Am J Respir Crit Care Med (1999) 3.71

Exposure to residential electric and magnetic fields and risk of childhood leukemia. Am J Epidemiol (1991) 3.49

On the need for the rare disease assumption in case-control studies. Am J Epidemiol (1982) 3.28

Biological models and statistical interactions: an example from multistage carcinogenesis. Int J Epidemiol (1981) 3.21

A study of twelve Southern California communities with differing levels and types of air pollution. II. Effects on pulmonary function. Am J Respir Crit Care Med (1999) 3.18

Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability. J Biol Chem (1994) 2.82

Simultaneously modelling censored survival data and repeatedly measured covariates: a Gibbs sampling approach. Stat Med (1996) 2.66

Effect of DNA polymerase I and DNA helicase II on the turnover rate of UvrABC excision nuclease. Proc Natl Acad Sci U S A (1985) 2.62

A cohort study of thyroid disease in relation to fallout from nuclear weapons testing. JAMA (1993) 2.62

Domainal evolution of a prokaryotic DNA repair protein and its relationship to active-transport proteins. Nature (1986) 2.35

Environmental tobacco smoke and absenteeism related to respiratory illness in schoolchildren. Am J Epidemiol (2003) 2.23

Amplification and purification of UvrA, UvrB, and UvrC proteins of Escherichia coli. J Biol Chem (1985) 2.11

Maternal smoking during pregnancy, environmental tobacco smoke exposure and childhood lung function. Thorax (2000) 2.06

Sequences of Escherichia coli uvrA gene and protein reveal two potential ATP binding sites. J Biol Chem (1986) 2.06

Air pollution and bronchitic symptoms in Southern California children with asthma. Environ Health Perspect (1999) 1.98

Biochemical studies on adenovirus multiplication. XV. Transcription of the adenovirus type II genome during productive infection. Virology (1969) 1.94

Nested case-control and case-cohort methods of sampling from a cohort: a critical comparison. Am J Epidemiol (1990) 1.75

Sequences of the E. coli uvrB gene and protein. Nucleic Acids Res (1986) 1.73

Testing linkage disequilibrium in sibships. Am J Hum Genet (2000) 1.65

Respiratory effects of relocating to areas of differing air pollution levels. Am J Respir Crit Care Med (2001) 1.64

Bias and efficiency in family-based gene-characterization studies: conditional, prospective, retrospective, and joint likelihoods. Am J Hum Genet (2000) 1.62

Biochemical studies on adenovirus multiplication. XVII. Ribosome synthesis in uninfected and infected KB cells. Virology (1970) 1.61

The effects of ambient air pollution on school absenteeism due to respiratory illnesses. Epidemiology (2001) 1.57

Personal and family history of lung disease as risk factors for adenocarcinoma of the lung. Cancer Res (1988) 1.56

Multilevel modeling in epidemiology with GLIMMIX. Epidemiology (2000) 1.54

Genome-wide screen for systemic lupus erythematosus susceptibility genes in multiplex families. Hum Mol Genet (1999) 1.50

The role of restricted motility in determining outcomes for vertical strabismus surgery in Graves' ophthalmology. Ophthalmology (2000) 1.49

Glutathione-S-transferase (GST) P1, GSTM1, exercise, ozone and asthma incidence in school children. Thorax (2008) 1.48

Genome scan of complex traits by haplotype sharing correlation. Genet Epidemiol (2001) 1.39

Simulation study of hierarchical regression. Stat Med (1996) 1.39

Leukemia in Utah and radioactive fallout from the Nevada test site. A case-control study. JAMA (1990) 1.37

Performance of Markov chain-Monte Carlo approaches for mapping genes in oligogenic models with an unknown number of loci. Am J Hum Genet (2000) 1.34

Effects of in utero and environmental tobacco smoke exposure on lung function in boys and girls with and without asthma. Am J Respir Crit Care Med (2000) 1.31

Activities and incision patterns of ABC excinuclease on modified DNA containing single-base mismatches and extrahelical bases. J Biol Chem (1986) 1.31

The rare-disease assumption revisited. A critique of "estimators of relative risk for case-control studies". Am J Epidemiol (1986) 1.26

Disease, lifestyle, and consanguinity in 58 American Gypsies. Lancet (1987) 1.24

Synergistic effect between IL-10 and bcl-2 genotypes in determining susceptibility to systemic lupus erythematosus. Arthritis Rheum (1998) 1.24

Family-based association studies. J Natl Cancer Inst Monogr (1999) 1.22

The relative efficiencies of matched and independent sample designs for case-control studies. J Chronic Dis (1983) 1.16

Fibre exposure and mortality from pneumoconiosis, respiratory and abdominal malignancies in chrysotile production in Quebec, 1926-75. Ann Acad Med Singapore (1984) 1.14

Exonucleolytic proofreading of leading and lagging strand DNA replication errors. Proc Natl Acad Sci U S A (1991) 1.14

International Genetic Epidemiology Society: commentary on Darkness in El Dorado by Patrick Tierney. Genet Epidemiol (2001) 1.13

Combined linkage and association analysis in pedigrees. Genet Epidemiol (2001) 1.12

Acid liability of rhinovirus type 14: effect of pH, time, and temperature. Proc Soc Exp Biol Med (1973) 1.09

Systems biological and mechanistic modelling of radiation-induced cancer. Radiat Environ Biophys (2007) 1.07

Prior exposure to medical and dental x-rays related to tumors of the parotid gland. J Natl Cancer Inst (1988) 1.07

Cohort studies for characterizing measured genes. J Natl Cancer Inst Monogr (1999) 1.07

Intravitreal penetration of oral ciprofloxacin in humans. Ophthalmology (1992) 1.07

Statistical methods for analyzing effects of temporal patterns of exposure on cancer risks. Scand J Work Environ Health (1983) 1.06

Predicting survival in adults with end-stage renal disease: an age equivalence index. Ann Intern Med (1982) 1.04

Genetic variations in nitric oxide synthase and arginase influence exhaled nitric oxide levels in children. Allergy (2010) 1.03

Sample size determination in case-control studies: the influence of the distribution of exposure. J Chronic Dis (1985) 1.01

The Utah Leukemia Case-Control Study: dosimetry methodology and results. Health Phys (1995) 1.01

Rhinovirus replication in suspension cultures of HeLa cells. Proc Soc Exp Biol Med (1970) 1.00

Counter-matching in studies of gene-environment interaction: efficiency and feasibility. Am J Epidemiol (2001) 0.98

Ascertainment bias in rate ratio estimation from case-sibling control studies of variable age-at-onset diseases. Biometrics (1999) 0.95

Noise trauma in the aetiology of acoustic neuromas in men in Los Angeles County, 1978-1985. Br J Cancer (1989) 0.95

Correcting for exposure measurement error in a reanalysis of lung cancer mortality for the Colorado Plateau Uranium Miners cohort. Health Phys (1999) 0.94

Anti-inflammatory therapy and outcome in a guinea pig model of Pseudomonas keratitis. Cornea (1992) 0.93

Risk for contralateral breast cancer among carriers of the CHEK2*1100delC mutation in the WECARE Study. Br J Cancer (2008) 0.93

Processed meats and risk of childhood leukemia (California, USA). Cancer Causes Control (1994) 0.92

Fluid dynamic characterization of operating conditions for continuous flow blood pumps. ASAIO J (1999) 0.92

Use of generalized estimating equations in segregation analysis of continuous outcomes. Genet Epidemiol (1993) 0.90

The efficiency of matching in case-control studies of risk-factor interactions. J Chronic Dis (1985) 0.90

Armadillo exposure among Mexican-born patients with lepromatous leprosy. J Infect Dis (1987) 0.90

Sex-specific effects of asthma on pulmonary function in children. Am J Respir Crit Care Med (2000) 0.90

Estimates of lifetime lung cancer risks resulting from Rn progeny exposure. Health Phys (1985) 0.90

Exposure to magnetic fields among electrical workers in relation to leukemia risk in Los Angeles County. Am J Ind Med (1994) 0.90

Censored survival models for genetic epidemiology: a Gibbs sampling approach. Genet Epidemiol (1994) 0.89

Does the gender difference in interferon production seen in picornavirus-infected spleen cell cultures from ICR Swiss mice have any in vivo significance? J Interferon Res (1993) 0.89

The Utah Thyroid Cohort Study: analysis of the dosimetry results. Health Phys (1995) 0.88

Diagnostic radiography as a risk factor for chronic myeloid and monocytic leukaemia (CML). Br J Cancer (1989) 0.87

Analysis of gene-smoking interaction in lung cancer. Genet Epidemiol (1997) 0.87

A generalized estimating equations approach to linkage analysis in sibships in relation to multiple markers and exposure factors. Genet Epidemiol (1999) 0.87

Study-design issues in the development of the University of Southern California Consortium's Colorectal Cancer Family Registry. J Natl Cancer Inst Monogr (1999) 0.86

A comparative trial of two walking systems for paralysed people. Paraplegia (1991) 0.86

Secular trends in histologic types of lung cancer. J Natl Cancer Inst (1986) 0.86

Re: "When will nondifferential misclassification of an exposure preserve the direction of a trend?". Am J Epidemiol (1995) 0.86

Re: "Conditions for confounding of the risk ratio and of the odds ratio". Am J Epidemiol (1986) 0.86

Efficiency of cohort sampling designs: some surprising results. Biometrics (1991) 0.85

Tropism and histopathology of the D, B, K, and MM variants of encephalomyocarditis virus. J Med Virol (1989) 0.84

Statistical methods for relating several exposure factors to several diseases in case-heterogeneity studies. Stat Med (1986) 0.84

The problem of multiple inference in identifying point-source environmental hazards. Environ Health Perspect (1985) 0.84

Multistage sampling for disease family registries. J Natl Cancer Inst Monogr (1999) 0.84

The role of interacting determinants in the localization of genes. Adv Genet (2001) 0.83

Association tests in nuclear families. Hum Hered (2001) 0.83

Characterisation of Mycoplasma pneumoniae growth factors in bovine serum fraction. J Med Microbiol (1974) 0.83

Suprasensitivity to calcitonin gene-related peptide but not vasoactive intestinal peptide in women with chronic pelvic pain. Clin Auton Res (1992) 0.83

Chronic animal health assessment during axial ventricular assistance: importance of hemorheologic parameters. ASAIO J (1999) 0.82

Association between the Rfp-Y haplotype and the incidence of Marek's disease in chickens. Immunogenetics (1996) 0.82