Published in Biochemistry on April 20, 1999
SH2 domains: modulators of nonreceptor tyrosine kinase activity. Curr Opin Struct Biol (2009) 1.45
A thermodynamic ligand binding study of the third PDZ domain (PDZ3) from the mammalian neuronal protein PSD-95. Biochemistry (2007) 1.25
Combining multiple structure and sequence alignments to improve sequence detection and alignment: application to the SH2 domains of Janus kinases. Proc Natl Acad Sci U S A (2001) 1.08
Constraining binding hot spots: NMR and molecular dynamics simulations provide a structural explanation for enthalpy-entropy compensation in SH2-ligand binding. J Am Chem Soc (2010) 1.02
Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads. EMBO J (2004) 1.00
Stability and peptide binding specificity of Btk SH2 domain: molecular basis for X-linked agammaglobulinemia. Protein Sci (2000) 1.00
Backbone nuclear relaxation characteristics and calorimetric investigation of the human Grb7-SH2/erbB2 peptide complex. Protein Sci (2005) 0.92
Computational analysis of phosphopeptide binding to the polo-box domain of the mitotic kinase PLK1 using molecular dynamics simulation. PLoS Comput Biol (2010) 0.85
Comparison of binding energies of SrcSH2-phosphotyrosyl peptides with structure-based prediction using surface area based empirical parameterization. Protein Sci (2000) 0.84
SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome. Cell Commun Signal (2012) 0.82
SH2 Ligand-Like Effects of Second Cytosolic Domain of Na/K-ATPase α1 Subunit on Src Kinase. PLoS One (2015) 0.80
Measurement of the formation of complexes in tyrosine kinase-mediated signal transduction. Acta Crystallogr D Biol Crystallogr (2006) 0.79
Tyrosine phosphorylation of the Lyn Src homology 2 (SH2) domain modulates its binding affinity and specificity. Mol Cell Proteomics (2015) 0.79
A new class of mutations reveals a novel function for the original phosphatidylinositol 3-kinase binding site. Proc Natl Acad Sci U S A (2003) 0.78
Dissection of the interaction between the intrinsically disordered YAP protein and the transcription factor TEAD. Elife (2017) 0.75
Major domain swiveling revealed by the crystal structures of complexes of E. coli Rep helicase bound to single-stranded DNA and ADP. Cell (1997) 4.71
Structural basis of chaperone function and pilus biogenesis. Science (1999) 3.69
Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2. Proc Natl Acad Sci U S A (1997) 3.66
Structure of the DNA binding domain of E. coli SSB bound to ssDNA. Nat Struct Biol (2000) 3.34
The biology and enzymology of protein N-myristoylation. J Biol Chem (2001) 3.14
Crystal structure of the hexameric traffic ATPase of the Helicobacter pylori type IV secretion system. Mol Cell (2000) 2.74
Synthetic protein transduction domains: enhanced transduction potential in vitro and in vivo. Cancer Res (2001) 2.54
Crystal structure of the homo-tetrameric DNA binding domain of Escherichia coli single-stranded DNA-binding protein determined by multiwavelength x-ray diffraction on the selenomethionyl protein at 2.9-A resolution. Proc Natl Acad Sci U S A (1997) 2.23
BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity. J Biol Chem (1997) 2.23
Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome. Proc Natl Acad Sci U S A (2000) 2.13
Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing. Mol Cell Biol (1998) 2.05
PapD-like chaperones provide the missing information for folding of pilin proteins. Proc Natl Acad Sci U S A (2000) 1.98
Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability. Proc Natl Acad Sci U S A (1995) 1.94
Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases. Protein Sci (1998) 1.93
Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates. Protein Sci (1998) 1.90
Structural basis of the interaction of the pyelonephritic E. coli adhesin to its human kidney receptor. Cell (2001) 1.79
Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. Proc Natl Acad Sci U S A (1999) 1.67
Hematopoietic malignancies demonstrate loss-of-function mutations of BAX. Blood (1998) 1.61
Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide. J Mol Biol (1998) 1.60
Nucleotide sequence of a gene encoding corn ribulose-1,5-bisphosphate carboxylase/oxygenase small subunit (rbcs). Nucleic Acids Res (1987) 1.53
Chaperone-assisted pilus assembly and bacterial attachment. Curr Opin Struct Biol (2000) 1.42
Mutations in GJB6 cause hidrotic ectodermal dysplasia. Nat Genet (2000) 1.42
Crystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivity. Protein Sci (2001) 1.40
FGF binding and FGF receptor activation by synthetic heparan-derived di- and trisaccharides. Science (1995) 1.38
Structure of N-myristoyltransferase with bound myristoylCoA and peptide substrate analogs. Nat Struct Biol (1998) 1.27
Investigation of phosphotyrosine recognition by the SH2 domain of the Src kinase. J Mol Biol (1999) 1.24
Calorimetric investigation of proton linkage by monitoring both the enthalpy and association constant of binding: application to the interaction of the Src SH2 domain with a high-affinity tyrosyl phosphopeptide. Biochemistry (1998) 1.21
Crystal structure of enteropeptidase light chain complexed with an analog of the trypsinogen activation peptide. J Mol Biol (1999) 1.19
Heparin-induced self-association of fibroblast growth factor-2. Evidence for two oligomerization processes. J Biol Chem (1997) 1.19
Structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoylCoA and peptide provide insights about substrate recognition and catalysis. Biochemistry (2001) 1.15
Thermodynamic study of the binding of the tandem-SH2 domain of the Syk kinase to a dually phosphorylated ITAM peptide: evidence for two conformers. Biochemistry (1999) 1.15
Unexpected crucial role of residue 225 in serine proteases. Proc Natl Acad Sci U S A (1999) 1.11
The structure of myristoyl-CoA:protein N-myristoyltransferase. Biochim Biophys Acta (1999) 1.08
Nucleotide sequence of a cDNA encoding the ribulose-1,5-bisphosphate carboxylase/oxygenase from sunflower (Helianthus annuus). Nucleic Acids Res (1987) 1.07
Probing the "two-pronged plug two-holed socket" model for the mechanism of binding of the Src SH2 domain to phosphotyrosyl peptides: a thermodynamic study. Biochemistry (1998) 1.05
Fusion of a cleavable signal peptide to the ectodomain of neutral endopeptidase (EC 3.4.24.11) results in the secretion of an active enzyme in COS-1 cells. J Biol Chem (1989) 1.05
Autoradiographic comparison of the distribution of the neutral endopeptidase "enkephalinase" and of mu and delta opioid receptors in rat brain. Proc Natl Acad Sci U S A (1986) 1.04
Crystallization of DsbA, an Escherichia coli protein required for disulphide bond formation in vivo. J Mol Biol (1993) 1.02
Structural biology of bacterial secretion systems in gram-negative pathogens--potential for new drug targets. Infect Disord Drug Targets (2009) 1.01
Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation. Proc Natl Acad Sci U S A (1996) 0.99
Mass spectrometric and thermodynamic studies reveal the role of water molecules in complexes formed between SH2 domains and tyrosyl phosphopeptides. Structure (1998) 0.95
Supraomohyoid neck dissection in the treatment of head and neck tumors. Survival results in 212 cases. Arch Otolaryngol Head Neck Surg (1993) 0.94
Common amino acid domain among endopolygalacturonases of ascomycete fungi. Appl Environ Microbiol (1990) 0.93
Analgesic effects of kelatorphan, a new highly potent inhibitor of multiple enkephalin degrading enzymes. Eur J Pharmacol (1984) 0.91
New insights into heparin-induced FGF oligomerization. Nat Struct Biol (1998) 0.89
Mutational investigation of the specificity determining region of the Src SH2 domain. J Mol Biol (2000) 0.88
Binding of the bidentate inhibitor [3H]HACBO-Gly to the rat brain neutral endopeptidase "enkephalinase". Biochem Biophys Res Commun (1985) 0.88
Role of electrostatic interactions in SH2 domain recognition: salt-dependence of tyrosyl-phosphorylated peptide binding to the tandem SH2 domain of the Syk kinase and the single SH2 domain of the Src kinase. Biochemistry (2000) 0.87
Synthesis of fluorescent acyl-cholines with agonistic properties: pharmacological activity on Electrophorus electroplaque and interaction in vitro with Torpedo receptor-rich membrane fragments. FEBS Lett (1976) 0.87
Pre-steady-state kinetic studies of Saccharomyces cerevisiae myristoylCoA:protein N-myristoyltransferase mutants identify residues involved in catalysis. Biochemistry (2001) 0.87
In vitro and in vivo effects of kelatorphan on enkephalin metabolism in rodent brain. Eur J Pharmacol (1985) 0.85
Recombinant neutral endopeptidase-24.11 expressed in mouse neuroblastoma cells is associated with neurite membranes. Biochem J (1990) 0.85
Differences in the structural requirements for selective interaction with neutral metalloendopeptidase (enkephalinase) or angiotensin-converting enzyme. Molecular investigation by use of new thiol inhibitors. Eur J Biochem (1984) 0.85
D2 dopamine receptor gene and alcoholism. J Psychiatr Res (1993) 0.85
SH2 domains: from structure to energetics, a dual approach to the study of structure-function relationships. Med Res Rev (1999) 0.84
Selective labelling by [3H]trimethisoquin azide of polypeptide chains present in acetylcholine receptor-rich membranes from Torpedo marmorata. FEBS Lett (1980) 0.83
Drosophila rab GDI mutants disrupt development but have normal Rab membrane extraction. Genesis (2001) 0.83
Differential recognition of "enkephalinase" and angiotensin-converting enzyme by new carboxyalkyl inhibitors. Life Sci (1982) 0.82
Human tyrosine hydroxylase isoforms. Inhibition by excess tetrahydropterin and unusual behavior of isoform 3 after camp-dependent protein kinase phosphorylation. J Biol Chem (1998) 0.81
Synthesis and pharmacological activity on Electrophorus electricus electroplaque of photoaffinity labelling derivatives of the non-competitive blockers di- and tri-methisoquin. FEBS Lett (1980) 0.81
[Regional distribution of enkephalinase in the rat brain by autoradiography]. C R Acad Sci III (1984) 0.80
Neuronal localization of the neutral endopeptidase 'enkephalinase' in rat brain revealed by lesions and autoradiography. EMBO J (1986) 0.80
Bidentate peptides: highly potent new inhibitors of enkephalin degrading enzymes. Life Sci (1984) 0.80
Connexin 30, a new marker of hyperproliferative epidermis. Br J Dermatol (2006) 0.80
The lon gene and photoprotection in Escherichia coli K-12. Photochem Photobiol (1984) 0.79
New bidentates as full inhibitors of enkephalin-degrading enzymes: synthesis and analgesic properties. J Med Chem (1985) 0.79
Kelatorphan: a full inhibitor of enkephalin degrading enzymes. Biochemical and pharmacological properties, regional distribution of enkephalinase in rat brain by use of a tritiated derivative. Neuropeptides (1985) 0.77
Regulation of antigen receptor function by protein tyrosine kinases. Prog Biophys Mol Biol (1999) 0.77
Pseudoautosomal region in schizophrenia: linkage analysis of seven loci by sib-pair and lod-score methods. Psychiatry Res (1994) 0.77
Structural analysis by circular dichroism of some enzymes involved in plant cell wall degradation. FEBS Lett (1991) 0.77
New enkephalinase inhibitors as probes to differentiate "enkephalinase" and angiotensin-converting-enzyme active sites. Life Sci (1983) 0.76
pH-Dependent self-association of the Src homology 2 (SH2) domain of the Src homologous and collagen-like (SHC) protein. Protein Sci (1996) 0.75
Targeting of neutral endopeptidase 24.11 in polarized cells. Biochem Soc Trans (1993) 0.75
[Contribution of satellite image processing to the cartography of sahelian pastures]. Rev Elev Med Vet Pays Trop (1977) 0.75
Refined localization of the gene for Clouston syndrome (hidrotic ectodermal dysplasia) in a large French family. Br J Dermatol (2000) 0.75
Naloxone-induced withdrawal syndrome after administration of selective opioid agonists or after activation of the endogenous enkephalinergic system. Prog Clin Biol Res (1990) 0.75
A 1.5-Mb physical map of the hidrotic ectodermal dysplasia (Clouston syndrome) gene region on human chromosome 13q11. Genomics (2000) 0.75
Structural requirements for agonist and noncompetitive blocking action of acylcholine derivatives on Electrophorus electricus electroplaque. Mol Pharmacol (1980) 0.75
[Surgical treatment of acute pancreatitis: experience at a general hospital]. Rev Paul Med (1990) 0.75