Published in Biochemistry on June 23, 1998
A phosphotyrosine displacement mechanism for activation of Src by PTPalpha. EMBO J (2000) 1.90
Electrostatic modulation in steroid receptor recruitment of LXXLL and FXXLF motifs. Mol Cell Biol (2003) 1.24
Signaling properties of a non-metazoan Src kinase and the evolutionary history of Src negative regulation. J Biol Chem (2008) 1.12
Alternative modes of binding of proteins with tandem SH2 domains. Protein Sci (2000) 1.05
Constraining binding hot spots: NMR and molecular dynamics simulations provide a structural explanation for enthalpy-entropy compensation in SH2-ligand binding. J Am Chem Soc (2010) 1.02
Regulation of the sodium bicarbonate cotransporter kNBC1 function: role of Asp(986), Asp(988) and kNBC1-carbonic anhydrase II binding. J Physiol (2002) 1.01
Stability and peptide binding specificity of Btk SH2 domain: molecular basis for X-linked agammaglobulinemia. Protein Sci (2000) 1.00
Thermodynamic characterization of the interaction between TRAF2 and tumor necrosis factor receptor peptides by isothermal titration calorimetry. Proc Natl Acad Sci U S A (2000) 0.93
Comparison of binding energies of SrcSH2-phosphotyrosyl peptides with structure-based prediction using surface area based empirical parameterization. Protein Sci (2000) 0.84
Reengineering the signaling properties of a Src family kinase. Biochemistry (2009) 0.82
Conformational determinants of phosphotyrosine peptides complexed with the Src SH2 domain. PLoS One (2010) 0.81
Measurement of the formation of complexes in tyrosine kinase-mediated signal transduction. Acta Crystallogr D Biol Crystallogr (2006) 0.79
Purification, crystallization and preliminary X-ray diffraction analysis of the Fyn SH2 domain and its complex with a phosphotyrosine peptide. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.79
Structural insights into the intertwined dimer of fyn SH2. Protein Sci (2015) 0.76
Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity. Structure (2016) 0.75
Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone. Cell (1997) 6.12
Major domain swiveling revealed by the crystal structures of complexes of E. coli Rep helicase bound to single-stranded DNA and ADP. Cell (1997) 4.71
ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo. EMBO J (1998) 4.46
Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin. J Med Chem (1999) 4.02
Structural basis of chaperone function and pilus biogenesis. Science (1999) 3.69
Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2. Proc Natl Acad Sci U S A (1997) 3.66
Structure of the DNA binding domain of E. coli SSB bound to ssDNA. Nat Struct Biol (2000) 3.34
The biology and enzymology of protein N-myristoylation. J Biol Chem (2001) 3.14
The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains. EMBO J (2000) 3.00
Crystal structure of the hexameric traffic ATPase of the Helicobacter pylori type IV secretion system. Mol Cell (2000) 2.74
Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones. EMBO J (1999) 2.71
Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation. Cell (1994) 2.61
Synthetic protein transduction domains: enhanced transduction potential in vitro and in vivo. Cancer Res (2001) 2.54
TCR binding to peptide-MHC stabilizes a flexible recognition interface. Immunity (1999) 2.33
Crystal structure of the homo-tetrameric DNA binding domain of Escherichia coli single-stranded DNA-binding protein determined by multiwavelength x-ray diffraction on the selenomethionyl protein at 2.9-A resolution. Proc Natl Acad Sci U S A (1997) 2.23
BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity. J Biol Chem (1997) 2.23
Two EGF molecules contribute additively to stabilization of the EGFR dimer. EMBO J (1997) 2.16
Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome. Proc Natl Acad Sci U S A (2000) 2.13
Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing. Mol Cell Biol (1998) 2.05
PapD-like chaperones provide the missing information for folding of pilin proteins. Proc Natl Acad Sci U S A (2000) 1.98
Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability. Proc Natl Acad Sci U S A (1995) 1.94
Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases. Protein Sci (1998) 1.93
Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates. Protein Sci (1998) 1.90
Structural basis of the interaction of the pyelonephritic E. coli adhesin to its human kidney receptor. Cell (2001) 1.79
Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate. Structure (1999) 1.74
Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. Proc Natl Acad Sci U S A (1999) 1.67
Hematopoietic malignancies demonstrate loss-of-function mutations of BAX. Blood (1998) 1.61
Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide. J Mol Biol (1998) 1.60
Nucleotide sequence of a gene encoding corn ribulose-1,5-bisphosphate carboxylase/oxygenase small subunit (rbcs). Nucleic Acids Res (1987) 1.53
Oligomerization of the chromatin-structuring protein H-NS. Mol Microbiol (2000) 1.50
Specific binding of hoechst 33258 to the d(CGCAAATTTGCG)2 duplex: calorimetric and spectroscopic studies. J Mol Biol (1997) 1.48
RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef. Biochemistry (1998) 1.43
Chaperone-assisted pilus assembly and bacterial attachment. Curr Opin Struct Biol (2000) 1.42
Mutations in GJB6 cause hidrotic ectodermal dysplasia. Nat Genet (2000) 1.42
Crystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivity. Protein Sci (2001) 1.40
The high-resolution crystal structure of a 24-kDa gyrase B fragment from E. coli complexed with one of the most potent coumarin inhibitors, clorobiocin. Proteins (1997) 1.40
FGF binding and FGF receptor activation by synthetic heparan-derived di- and trisaccharides. Science (1995) 1.38
Crystallographic and calorimetric analysis of peptide binding to OppA protein. J Mol Biol (1999) 1.35
Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans. Genes Brain Behav (2010) 1.35
Structure of N-myristoyltransferase with bound myristoylCoA and peptide substrate analogs. Nat Struct Biol (1998) 1.27
Investigation of phosphotyrosine recognition by the SH2 domain of the Src kinase. J Mol Biol (1999) 1.24
The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases. J Biol Chem (2001) 1.21
Calorimetric investigation of proton linkage by monitoring both the enthalpy and association constant of binding: application to the interaction of the Src SH2 domain with a high-affinity tyrosyl phosphopeptide. Biochemistry (1998) 1.21
Crystal structure of enteropeptidase light chain complexed with an analog of the trypsinogen activation peptide. J Mol Biol (1999) 1.19
Heparin-induced self-association of fibroblast growth factor-2. Evidence for two oligomerization processes. J Biol Chem (1997) 1.19
Structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoylCoA and peptide provide insights about substrate recognition and catalysis. Biochemistry (2001) 1.15
Thermodynamic study of the binding of the tandem-SH2 domain of the Syk kinase to a dually phosphorylated ITAM peptide: evidence for two conformers. Biochemistry (1999) 1.15
The role of water in sequence-independent ligand binding by an oligopeptide transporter protein. Nat Struct Biol (1996) 1.15
Thermodynamic studies of tyrosyl-phosphopeptide binding to the SH2 domain of p56lck. Biochemistry (1994) 1.13
Water-mediated protein-DNA interactions: the relationship of thermodynamics to structural detail. Protein Sci (1996) 1.13
Unexpected crucial role of residue 225 in serine proteases. Proc Natl Acad Sci U S A (1999) 1.11
The effects of salt on the TATA binding protein-DNA interaction from a hyperthermophilic archaeon. J Mol Biol (1998) 1.09
The structure of myristoyl-CoA:protein N-myristoyltransferase. Biochim Biophys Acta (1999) 1.08
Nucleotide sequence of a cDNA encoding the ribulose-1,5-bisphosphate carboxylase/oxygenase from sunflower (Helianthus annuus). Nucleic Acids Res (1987) 1.07
Alternative modes of binding of proteins with tandem SH2 domains. Protein Sci (2000) 1.05
Fusion of a cleavable signal peptide to the ectodomain of neutral endopeptidase (EC 3.4.24.11) results in the secretion of an active enzyme in COS-1 cells. J Biol Chem (1989) 1.05
Autoradiographic comparison of the distribution of the neutral endopeptidase "enkephalinase" and of mu and delta opioid receptors in rat brain. Proc Natl Acad Sci U S A (1986) 1.04
Independent binding of peptide ligands to the SH2 and SH3 domains of Grb2. J Biol Chem (1994) 1.03
Crystallization of DsbA, an Escherichia coli protein required for disulphide bond formation in vivo. J Mol Biol (1993) 1.02
Structural biology of bacterial secretion systems in gram-negative pathogens--potential for new drug targets. Infect Disord Drug Targets (2009) 1.01
Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation. Proc Natl Acad Sci U S A (1996) 0.99
The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data. Transl Psychiatry (2011) 0.99
Calorimetric examination of high-affinity Src SH2 domain-tyrosyl phosphopeptide binding: dissection of the phosphopeptide sequence specificity and coupling energetics. Biochemistry (1999) 0.97
Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase. Biochemistry (1996) 0.96
Dynamics of a monomeric insulin analogue: testing the molten-globule hypothesis. Biochemistry (1993) 0.95
Mass spectrometric and thermodynamic studies reveal the role of water molecules in complexes formed between SH2 domains and tyrosyl phosphopeptides. Structure (1998) 0.95
Structural characterization of the N-terminal oligomerization domain of the bacterial chromatin-structuring protein, H-NS. J Mol Biol (2001) 0.95
Supraomohyoid neck dissection in the treatment of head and neck tumors. Survival results in 212 cases. Arch Otolaryngol Head Neck Surg (1993) 0.94
Localization and characterization of the hyaluronan-binding site on the link module from human TSG-6. Structure (2000) 0.93
Common amino acid domain among endopolygalacturonases of ascomycete fungi. Appl Environ Microbiol (1990) 0.93
A ribonuclease S-peptide antagonist discovered with a bacteriophage display library. Gene (1993) 0.92
Analgesic effects of kelatorphan, a new highly potent inhibitor of multiple enkephalin degrading enzymes. Eur J Pharmacol (1984) 0.91
Specificity and interactions of the protein OppA: partitioning solvent binding effects using mass spectrometry. J Mol Biol (2000) 0.91
Characterization of sequence-specific DNA binding by the transcription factor Oct-1. Biochemistry (2000) 0.90
New insights into heparin-induced FGF oligomerization. Nat Struct Biol (1998) 0.89
Site-specific cation binding mediates TATA binding protein-DNA interaction from a hyperthermophilic archaeon. Biochemistry (2001) 0.89
Mutational investigation of the specificity determining region of the Src SH2 domain. J Mol Biol (2000) 0.88
Binding of the bidentate inhibitor [3H]HACBO-Gly to the rat brain neutral endopeptidase "enkephalinase". Biochem Biophys Res Commun (1985) 0.88
Role of electrostatic interactions in SH2 domain recognition: salt-dependence of tyrosyl-phosphorylated peptide binding to the tandem SH2 domain of the Syk kinase and the single SH2 domain of the Src kinase. Biochemistry (2000) 0.87
Halophilic adaptation of protein-DNA interactions. Biochem Soc Trans (2003) 0.87
Synthesis of fluorescent acyl-cholines with agonistic properties: pharmacological activity on Electrophorus electroplaque and interaction in vitro with Torpedo receptor-rich membrane fragments. FEBS Lett (1976) 0.87
Pre-steady-state kinetic studies of Saccharomyces cerevisiae myristoylCoA:protein N-myristoyltransferase mutants identify residues involved in catalysis. Biochemistry (2001) 0.87
A structural characterization of the interactions between titin Z-repeats and the alpha-actinin C-terminal domain. Biochemistry (2001) 0.87
D2 dopamine receptor gene and alcoholism. J Psychiatr Res (1993) 0.85
Recombinant neutral endopeptidase-24.11 expressed in mouse neuroblastoma cells is associated with neurite membranes. Biochem J (1990) 0.85
In vitro and in vivo effects of kelatorphan on enkephalin metabolism in rodent brain. Eur J Pharmacol (1985) 0.85
Differences in the structural requirements for selective interaction with neutral metalloendopeptidase (enkephalinase) or angiotensin-converting enzyme. Molecular investigation by use of new thiol inhibitors. Eur J Biochem (1984) 0.85
Structural basis for recognition of dipeptides by peptide transporters. Arch Biochem Biophys (2000) 0.85
Comparison of binding energies of SrcSH2-phosphotyrosyl peptides with structure-based prediction using surface area based empirical parameterization. Protein Sci (2000) 0.84
SH2 domains: from structure to energetics, a dual approach to the study of structure-function relationships. Med Res Rev (1999) 0.84
A complex of Shc and Ran-GTPase localises to the cell nucleus. Cell Mol Life Sci (2009) 0.83
Selective labelling by [3H]trimethisoquin azide of polypeptide chains present in acetylcholine receptor-rich membranes from Torpedo marmorata. FEBS Lett (1980) 0.83
Inhibitors to the Src SH2 domain: a lesson in structure--thermodynamic correlation in drug design. Arch Biochem Biophys (2001) 0.83
Specific DNA recognition by the type II restriction endonuclease MunI: the effect of pH. Biochemistry (2001) 0.83
Drosophila rab GDI mutants disrupt development but have normal Rab membrane extraction. Genesis (2001) 0.83
Differential recognition of "enkephalinase" and angiotensin-converting enzyme by new carboxyalkyl inhibitors. Life Sci (1982) 0.82