Published in Biochim Biophys Acta on May 06, 1999
Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network. Nat Cell Biol (2004) 2.59
Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone. J Biol Chem (2008) 1.74
Structural requirements for localization and activation of protein kinase C mu (PKC mu) at the Golgi compartment. J Cell Biol (2002) 1.57
Sequential protein kinase C (PKC)-dependent and PKC-independent protein kinase D catalytic activation via Gq-coupled receptors: differential regulation of activation loop Ser(744) and Ser(748) phosphorylation. J Biol Chem (2008) 1.50
Spatial and temporal regulation of protein kinase D (PKD). EMBO J (2000) 1.38
Targeting vascular endothelial growth factor receptor 2 and protein kinase D1 related pathways by a multiple kinase inhibitor in angiogenesis and inflammation related processes in vitro. PLoS One (2015) 1.38
Protein kinase D as a potential new target for cancer therapy. Biochim Biophys Acta (2010) 1.25
Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility. BMC Chem Biol (2010) 1.20
Role of protein kinase D signaling in pancreatic cancer. Biochem Pharmacol (2010) 1.14
Role of the regulatory domain of protein kinase D2 in phorbol ester binding, catalytic activity, and nucleocytoplasmic shuttling. Mol Biol Cell (2005) 1.10
Disruption of Epstein-Barr virus latency in the absence of phosphorylation of ZEBRA by protein kinase C. J Virol (2002) 1.03
Spatiotemporally distinct protein kinase D activation in adult cardiomyocytes in response to phenylephrine and endothelin. J Biol Chem (2011) 1.02
Induced overexpression of protein kinase D1 stimulates mitogenic signaling in human pancreatic carcinoma PANC-1 cells. J Cell Physiol (2010) 1.01
Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2. EMBO J (2007) 1.00
Design, Synthesis, and Biological Evaluation of PKD Inhibitors. Pharmaceutics (2011) 0.99
Sphingomyelin synthases regulate protein trafficking and secretion. PLoS One (2011) 0.96
Characterization of EVL-I as a protein kinase D substrate. Cell Signal (2008) 0.92
A protein kinase Cdelta-dependent protein kinase D pathway modulates ERK1/2 and JNK1/2 phosphorylation and Bim-associated apoptosis by asbestos. Am J Pathol (2008) 0.91
Protein kinase D regulates RhoA activity via rhotekin phosphorylation. J Biol Chem (2012) 0.88
Heterozygous disruption of Flk-1 receptor leads to myocardial ischaemia reperfusion injury in mice: application of affymetrix gene chip analysis. J Cell Mol Med (2008) 0.88
Expression patterns of protein kinase D 3 during mouse development. BMC Dev Biol (2008) 0.88
Protein kinase D regulates several aspects of development in Drosophila melanogaster. BMC Dev Biol (2007) 0.88
Inducible silencing of protein kinase D3 inhibits secretion of tumor-promoting factors in prostate cancer. Mol Cancer Ther (2012) 0.87
A protein kinase C/protein kinase D pathway protects LNCaP prostate cancer cells from phorbol ester-induced apoptosis by promoting ERK1/2 and NF-{kappa}B activities. Carcinogenesis (2011) 0.84
Involvement of protein kinase D in Fc gamma-receptor activation of the NADPH oxidase in neutrophils. Biochem J (2002) 0.82
Differential expression of cancer-related genes by single and permanent exposure to bone morphogenetic protein 2. J Cancer Res Clin Oncol (2008) 0.82
Protein kinase D1, a new molecular player in VEGF signaling and angiogenesis. Mol Cells (2009) 0.82
Protein kinase D isozymes activation and localization during mitosis. Exp Cell Res (2008) 0.81
Functional and therapeutic significance of protein kinase D enzymes in invasive breast cancer. Cell Mol Life Sci (2015) 0.80
Protein kinase C isoforms in the enteric nervous system. Histochem Cell Biol (2003) 0.80
Protein kinase Cδ mediates the activation of protein kinase D2 in platelets. Biochem Pharmacol (2011) 0.79
Protein kinase D1 is essential for bone acquisition during pubertal growth. Endocrinology (2013) 0.78
SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest. PLoS One (2015) 0.76
[Pharmacological treatment of diabetic retinopathy]. Ophthalmologe (2004) 0.75
PKD3 deficiency causes alterations in microtubule dynamics during the cell cycle. Cell Cycle (2016) 0.75
Androgen suppresses protein kinase D1 expression through fibroblast growth factor receptor substrate 2 in prostate cancer cells. Oncotarget (2017) 0.75
Emergency Spatiotemporal Shift: The Response of Protein Kinase D to Stress Signals in the Cardiovascular System. Front Pharmacol (2017) 0.75
Potein Kinase D Signaling in Cancer: A Friend or Foe? Biochim Biophys Acta (2017) 0.75
Functional annotation of a full-length mouse cDNA collection. Nature (2001) 23.61
A gene map of the human genome. Science (1996) 14.32
The genome of the social amoeba Dictyostelium discoideum. Nature (2005) 9.18
Interaction of tyrosine-based sorting signals with clathrin-associated proteins. Science (1995) 7.77
Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics (1996) 6.83
Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor. Nature (1986) 6.67
Green revolution: a mutant gibberellin-synthesis gene in rice. Nature (2002) 5.84
Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization. J Exp Med (1999) 5.55
Denitrification and ammonia formation in anaerobic coastal sediments. Appl Environ Microbiol (1978) 4.63
Genetic analysis of novel avian A(H7N9) influenza viruses isolated from patients in China, February to April 2013. Euro Surveill (2013) 4.44
Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine. Muscle Nerve (1995) 3.84
Failure to synthesize the T cell CD3-zeta chain: structure and function of a partial T cell receptor complex. Cell (1988) 3.59
Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene. Nat Genet (1994) 3.39
Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas. Nat Genet (1998) 3.38
Function of the 30 kd protein of tobacco mosaic virus: involvement in cell-to-cell movement and dispensability for replication. EMBO J (1987) 2.78
Cloning and complete nucleotide sequence of the Escherichia coli glutamine permease operon (glnHPQ). Mol Gen Genet (1986) 2.73
Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. Immunity (1995) 2.70
Simultaneous determinations of nitrification and nitrate reduction in coastal sediments by a 15N dilution technique. Appl Environ Microbiol (1978) 2.66
Interferon gamma production by natural killer (NK) cells and NK1.1+ T cells upon NKR-P1 cross-linking. J Exp Med (1996) 2.62
Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes. Immunity (1994) 2.61
Functionally related motor neuron pool and muscle sensory afferent subtypes defined by coordinate ETS gene expression. Cell (1998) 2.57
Temperature-induced A-B intersite charge transfer in an A-site-ordered LaCu(3)Fe(4)O(12) perovskite. Nature (2009) 2.57
miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer. Br J Cancer (2010) 2.51
Morbid obesity rates continue to rise rapidly in the United States. Int J Obes (Lond) (2013) 2.50
An extracellular poly(3-hydroxybutyrate) depolymerase from Alcaligenes faecalis. Eur J Biochem (1982) 2.49
Mu1B, a novel adaptor medium chain expressed in polarized epithelial cells. FEBS Lett (1999) 2.37
The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen. EMBO J (1997) 2.34
T cell activation-associated hepatic injury: mediation by tumor necrosis factors and protection by interleukin 6. J Exp Med (1994) 2.31
FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. Immunity (2002) 2.31
A simple procedure for mass spectrometric microanalysis of 15N in particulate organic matter with special reference to 15N-tracer experiments. Anal Biochem (1977) 2.31
Quantitative isolation of total glycosphingolipids from animal cells. J Lipid Res (1971) 2.29
Antigen-specific suppressive factor produced by a transplantable I-J bearing T-cell hybridoma. Nature (1979) 2.28
The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. Br J Cancer (2011) 2.25
The medium subunits of adaptor complexes recognize distinct but overlapping sets of tyrosine-based sorting signals. J Biol Chem (1998) 2.21
Membrane hyperpolarization inhibits agonist-induced synthesis of inositol 1,4,5-trisphosphate in rabbit mesenteric artery. J Physiol (1992) 2.20
Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL). J Biol Chem (2000) 2.18
Specific antigen-Ia activation of transfected human T cells expressing murine Ti alpha beta-human T3 receptor complexes. Nature (1987) 2.11
Cutting edge: the mouse NK cell-associated antigen recognized by DX5 monoclonal antibody is CD49b (alpha 2 integrin, very late antigen-2). J Immunol (2001) 2.09
Influence of dentition status on physical disability, mental impairment, and mortality in institutionalized elderly people. J Dent Res (2001) 2.06
Molecular cloning and characterization of a cDNA encoding the gibberellin biosynthetic enzyme ent-kaurene synthase B from pumpkin (Cucurbita maxima L.). Plant J (1996) 2.04
The Dictyostelium developmental cDNA project: generation and analysis of expressed sequence tags from the first-finger stage of development. DNA Res (1998) 2.03
Domain-specific mutations in TGFB1 result in Camurati-Engelmann disease. Nat Genet (2000) 2.02
Human soluble IL-6 receptor: its detection and enhanced release by HIV infection. J Immunol (1992) 1.99
Spondyloarthropathies in Japan: nationwide questionnaire survey performed by the Japan Ankylosing Spondylitis Society. J Rheumatol (2001) 1.99
Studies on erythrocyte glycolysis. I. Determination of the glycolytic intermediates in human erythrocytes. J Biochem (1965) 1.97
Fas-mediated cytotoxicity by freshly isolated natural killer cells. J Exp Med (1995) 1.97
Intramembranous fine deposit disease associated with collagen disorders: a new morphological entity? Virchows Arch A Pathol Anat Histopathol (1992) 1.97
Fluorescent leprosy antibody absorption (FLA-ABS) test for detecting subclinical infection with Mycobacterium leprae. Int J Lepr Other Mycobact Dis (1980) 1.97
Laparoscopic removal of a large gastric trichobezoar. J Pediatr Surg (1998) 1.96
Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2. Immunity (1997) 1.94
Effect of side-chain deuteration on protein stability. Biochemistry (1965) 1.94
Polymorphism of the 5'-flanking region of the human tumor necrosis factor (TNF)-alpha gene in Japanese. Tissue Antigens (1998) 1.93
Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins. DNA Res (1997) 1.92
Formation of bone and cartilage by marrow stromal cells in diffusion chambers in vivo. Clin Orthop Relat Res (1980) 1.91
Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells. Genes Dev (1991) 1.90
Characterization of a new avian-like influenza A virus from horses in China. Virology (1992) 1.90
Structure and functional analysis of a marine bacterial carotenoid biosynthesis gene cluster and astaxanthin biosynthetic pathway proposed at the gene level. J Bacteriol (1995) 1.90
Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25. J Biol Chem (2000) 1.89
Cell-specific expression of RANTES, MCP-1, and MIP-1alpha by lower airway epithelial cells and eosinophils infected with respiratory syncytial virus. J Virol (1998) 1.88
Resistance of Fc receptor- deficient mice to fatal glomerulonephritis. J Clin Invest (1998) 1.88
Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res (1997) 1.87
Cyclosporin in idiopathic glomerular disease associated with the nephrotic syndrome : workshop recommendations. Kidney Int (2007) 1.86
Age-related changes in the subsets and functions of human T lymphocytes. J Immunol (1978) 1.82
Giant hydronephrosis due to a ureteral stone, and elevated serum levels of CA 19-9. Intern Med (1999) 1.80
A gene (sleB) encoding a spore cortex-lytic enzyme from Bacillus subtilis and response of the enzyme to L-alanine-mediated germination. J Bacteriol (1996) 1.79
Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 zeta chain of T-cell receptor complex and antigen-specific T-cell responses. Proc Natl Acad Sci U S A (1996) 1.79
The role of macrophages in diabetic glomerulosclerosis. Am J Kidney Dis (1993) 1.77
N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8. Eur J Biochem (2001) 1.76
The narX and narL genes encoding the nitrate-sensing regulators of Escherichia coli are homologous to a family of prokaryotic two-component regulatory genes. Nucleic Acids Res (1989) 1.75
Energy yield of denitrification: an estimate from growth yield in continuous cultures of Pseudomonas denitrificans under nitrate-, nitrite- and oxide-limited conditions. J Gen Microbiol (1975) 1.74
Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer. Br J Cancer (2011) 1.74
Presence of interchain disulfide bonds between two gene products that compose the secreted form of an antigen-specific suppressor factor. J Exp Med (1981) 1.73
Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5). Proc Natl Acad Sci U S A (1996) 1.72
Apolipoprotein E Sendai (arginine 145-->proline): a new variant associated with lipoprotein glomerulopathy. J Am Soc Nephrol (1997) 1.71
The new lead citrate method for the ultracytochemical demonstration of activity of non-specific alkaline phosphatase (orthophosphoric monoester phosphohydrolase). Histochemie (1967) 1.71
Cloning of an intracellular Poly[D(-)-3-Hydroxybutyrate] depolymerase gene from Ralstonia eutropha H16 and characterization of the gene product. J Bacteriol (2001) 1.70
Purification and characterization of soluble human IL-6 receptor expressed in CHO cells. J Biochem (1990) 1.69
Moderate and severe endometriosis is associated with alterations in the cell cycle of granulosa cells in patients undergoing in vitro fertilization and embryo transfer. Fertil Steril (2000) 1.69
Polymerase chain reaction with confronting two-pair primers for polymorphism genotyping. Jpn J Cancer Res (2000) 1.67
Review of influenza A virus in swine worldwide: a call for increased surveillance and research. Zoonoses Public Health (2013) 1.67
Association with FcRgamma is essential for activation signal through NKR-P1 (CD161) in natural killer (NK) cells and NK1.1+ T cells. J Exp Med (1997) 1.66
A germination-specific spore cortex-lytic enzyme from Bacillus cereus spores: cloning and sequencing of the gene and molecular characterization of the enzyme. J Bacteriol (1996) 1.65
Inhibition of rho-associated kinase results in suppression of neointimal formation of balloon-injured arteries. Circulation (2000) 1.65
Flow-induced dilation of human coronary arterioles: important role of Ca(2+)-activated K(+) channels. Circulation (2001) 1.65
Three AML patients with existing or pre-existing intracerebral granulocytic sarcomas who were successfully treated with allogeneic bone marrow transplantations. Bone Marrow Transplant (1999) 1.65
Estimates of denitrification and nitrification in coastal and estuarine sediments. Appl Environ Microbiol (1983) 1.64
miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC). Br J Cancer (2010) 1.61
Role of interleukin 1 in promoting human monocyte-mediated tumor cytotoxicity. J Immunol (1985) 1.61
Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice. Proc Natl Acad Sci U S A (1997) 1.61
Horseshoe crab acetyl group-recognizing lectins involved in innate immunity are structurally related to fibrinogen. Proc Natl Acad Sci U S A (1999) 1.60
Lymph node metastasis as a significant prognostic factor in gastric cancer: a multiple logistic regression analysis. Scand J Gastroenterol (2004) 1.59
On the mode of action of a new antifungal antibiotic, aculeacin A: inhibition of cell wall synthesis in Saccharomyces cerevisiae. J Antibiot (Tokyo) (1977) 1.59