Published in Biochim Biophys Acta on May 05, 1999
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Endogenous nitric oxide protects bacteria against a wide spectrum of antibiotics. Science (2009) 2.32
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Bacterial nitric-oxide synthases operate without a dedicated redox partner. J Biol Chem (2008) 1.41
A novel genetic polymorphism of inducible nitric oxide synthase is associated with an increased risk of gastric cancer. World J Gastroenterol (2004) 1.40
Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain. FEBS J (2009) 1.39
Structural basis for endothelial nitric oxide synthase binding to calmodulin. EMBO J (2003) 1.37
AMP-activated protein kinase activation as a strategy for protecting vascular endothelial function. Clin Exp Pharmacol Physiol (2007) 1.35
Identification of the gene encoding alkylglycerol monooxygenase defines a third class of tetrahydrobiopterin-dependent enzymes. Proc Natl Acad Sci U S A (2010) 1.33
Macrophage nitric oxide synthase associates with cortical actin but is not recruited to phagosomes. Infect Immun (2001) 1.30
Innate immunity signaling: cytosolic Ca2+ elevation is linked to downstream nitric oxide generation through the action of calmodulin or a calmodulin-like protein. Plant Physiol (2008) 1.28
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Glyceryl ether monooxygenase resembles aromatic amino acid hydroxylases in metal ion and tetrahydrobiopterin dependence. Biol Chem (2009) 1.14
Repression of SPI2 transcription by nitric oxide-producing, IFNgamma-activated macrophages promotes maturation of Salmonella phagosomes. J Exp Med (2005) 1.13
Regulation of inducible nitric oxide synthase by rapid cellular turnover and cotranslational down-regulation by dimerization inhibitors. Proc Natl Acad Sci U S A (2004) 1.12
The shaping of nitric oxide signals by a cellular sink. J Physiol (2001) 1.11
Transcriptional regulation of the flavohemoglobin gene for aerobic nitric oxide detoxification by the second nitric oxide-responsive regulator of Pseudomonas aeruginosa. J Bacteriol (2005) 1.11
Role of oxidative stress and nitric oxide in atherothrombosis. Front Biosci (2008) 1.10
Evolution of the arginase fold and functional diversity. Cell Mol Life Sci (2008) 1.09
Nitric oxide synthases in heart failure. Antioxid Redox Signal (2012) 1.07
Vasodilatation, oxygen delivery and oxygen consumption in rat hindlimb during systemic hypoxia: roles of nitric oxide. J Physiol (2001) 1.06
Nitric oxide deficiency in pulmonary hypertension: Pathobiology and implications for therapy. Pulm Circ (2013) 1.05
Myeloperoxidase up-regulates the catalytic activity of inducible nitric oxide synthase by preventing nitric oxide feedback inhibition. Proc Natl Acad Sci U S A (2003) 1.05
The specificity of nitroxyl chemistry is unique among nitrogen oxides in biological systems. Antioxid Redox Signal (2011) 1.04
The mechanism of ciliary stimulation by acetylcholine: roles of calcium, PKA, and PKG. J Gen Physiol (2002) 1.04
Inhibition of inducible nitric oxide controls pathogen load and brain damage by enhancing phagocytosis of Escherichia coli K1 in neonatal meningitis. Am J Pathol (2010) 1.02
Photoreceptor mitochondrial oxidative stress in early experimental autoimmune uveoretinitis. Br J Ophthalmol (2006) 1.02
Nitric oxide protects bacteria from aminoglycosides by blocking the energy-dependent phases of drug uptake. Antimicrob Agents Chemother (2011) 1.02
Induction of angiogenesis by heat shock protein 90 mediated by protein kinase Akt and endothelial nitric oxide synthase. Arterioscler Thromb Vasc Biol (2004) 1.01
Intracellular formation of "undisruptable" dimers of inducible nitric oxide synthase. Proc Natl Acad Sci U S A (2003) 1.00
Zinc-binding cysteines: diverse functions and structural motifs. Biomolecules (2014) 1.00
Arginase 1 regulation of nitric oxide production is key to survival of trophic factor-deprived motor neurons. J Neurosci (2006) 0.99
Regulation of iNOS function and cellular redox state by macrophage Gch1 reveals specific requirements for tetrahydrobiopterin in NRF2 activation. Free Radic Biol Med (2014) 0.97
Superoxide induces endothelial nitric-oxide synthase protein thiyl radical formation, a novel mechanism regulating eNOS function and coupling. J Biol Chem (2011) 0.97
Surface charges and regulation of FMN to heme electron transfer in nitric-oxide synthase. J Biol Chem (2010) 0.97
Gasotransmitters in cancer: from pathophysiology to experimental therapy. Nat Rev Drug Discov (2015) 0.96
A bridging interaction allows calmodulin to activate NO synthase through a bi-modal mechanism. J Biol Chem (2010) 0.96
Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramide. Proc Natl Acad Sci U S A (2000) 0.96
Na+ - and Cl- -coupled active transport of nitric oxide synthase inhibitors via amino acid transport system B(0,+). J Clin Invest (2001) 0.96
Leaf senescence signaling: the Ca2+-conducting Arabidopsis cyclic nucleotide gated channel2 acts through nitric oxide to repress senescence programming. Plant Physiol (2010) 0.96
Nitric oxide in adaptation to altitude. Free Radic Biol Med (2012) 0.96
Visualizing inducible nitric-oxide synthase in living cells with a heme-binding fluorescent inhibitor. Proc Natl Acad Sci U S A (2005) 0.95
Potential biological chemistry of hydrogen sulfide (H2S) with the nitrogen oxides. Free Radic Biol Med (2012) 0.95
Inhibition of autophagy and glycolysis by nitric oxide during hypoxia-reoxygenation impairs cellular bioenergetics and promotes cell death in primary neurons. Free Radic Biol Med (2013) 0.92
The physiologic aggresome mediates cellular inactivation of iNOS. Proc Natl Acad Sci U S A (2009) 0.92
Inhibition of nitric oxide synthase by cobalamins and cobinamides. Free Radic Biol Med (2009) 0.91
Stabilization and characterization of a heme-oxy reaction intermediate in inducible nitric-oxide synthase. J Biol Chem (2008) 0.91
Enzymic degradation of plasma arginine using arginine deiminase inhibits nitric oxide production and protects mice from the lethal effects of tumour necrosis factor alpha and endotoxin. Biochem J (2002) 0.90
Nicotinic receptor alpha 7-subunits are coupled to the stimulation of nitric oxide synthase in rat dorsal root ganglion neurons. Histochem Cell Biol (2003) 0.90
The kallikrein-kinin system in diabetic nephropathy. Kidney Int (2012) 0.90
The placental pursuit for an adequate oxidant balance between the mother and the fetus. Front Pharmacol (2014) 0.90
Identification of the cysteine nitrosylation sites in human endothelial nitric oxide synthase. DNA Cell Biol (2008) 0.89
Regulation of multimers via truncated isoforms: a novel mechanism to control nitric-oxide signaling. Genes Dev (2004) 0.89
Nitric oxide metabolism in asthma pathophysiology. Biochim Biophys Acta (2011) 0.89
GTP cyclohydrolase I expression is regulated by nitric oxide: role of cyclic AMP. Am J Physiol Lung Cell Mol Physiol (2009) 0.88
Role of calcium in metalloenzymes: effects of calcium removal on the axial ligation geometry and magnetic properties of the catalytic diheme center in MauG. Biochemistry (2012) 0.88
Calmodulin phosphorylation and modulation of endothelial nitric oxide synthase catalysis. Proc Natl Acad Sci U S A (2004) 0.87
There's more to the picture than meets the eye: nitric oxide cross talk with Ca2+ signaling. Plant Physiol (2013) 0.87
Role of arginine guanidinium moiety in nitric-oxide synthase mechanism of oxygen activation. J Biol Chem (2009) 0.87
Nitric oxide increases oxidative phosphorylation efficiency. J Bioenerg Biomembr (2007) 0.87
Cyclic nucleotide gated channels and related signaling components in plant innate immunity. Plant Signal Behav (2009) 0.87
Adaptive immune defects against glycoantigens in chronic granulomatous disease via dysregulated nitric oxide production. Eur J Immunol (2011) 0.86
Arginine depletion increases susceptibility to serious infections in preterm newborns. Pediatr Res (2014) 0.85
Nitric oxide, oxygen, and superoxide formation and consumption in macrophages and colonic epithelial cells. Chem Res Toxicol (2010) 0.85
Current therapeutic strategies to mitigate the eNOS dysfunction in ischaemic stroke. Cell Mol Neurobiol (2011) 0.85
Nitric oxide synthase isoforms expression in fibroblasts isolated from human normal peritoneum and adhesion tissues. Fertil Steril (2008) 0.85
Charge-pairing interactions control the conformational setpoint and motions of the FMN domain in neuronal nitric oxide synthase. Biochem J (2013) 0.85
Nitric oxide inhibits isoproterenol-stimulated adipocyte lipolysis through oxidative inactivation of the beta-agonist. Biochem J (2000) 0.85
Mechanism of inducible nitric-oxide synthase dimerization inhibition by novel pyrimidine imidazoles. J Biol Chem (2013) 0.85
S-nitrosylation of caspase-3 is the mechanism by which adhesion fibroblasts manifest lower apoptosis. Wound Repair Regen (2009) 0.85
Pivotal role of c-Fos in nitric oxide synthase 2 expression in airway epithelial cells. Nitric Oxide (2008) 0.84
Plant Survival in a Changing Environment: The Role of Nitric Oxide in Plant Responses to Abiotic Stress. Front Plant Sci (2015) 0.84
Mechanisms by which licochalcone e exhibits potent anti-inflammatory properties: studies with phorbol ester-treated mouse skin and lipopolysaccharide-stimulated murine macrophages. Int J Mol Sci (2013) 0.84
Oxygen tension limits nitric oxide synthesis by activated macrophages. Biochem J (2000) 0.84
Src kinase-mediated phosphorylation stabilizes inducible nitric-oxide synthase in normal cells and cancer cells. J Biol Chem (2009) 0.84
Pathological basis of symptoms and crises in sickle cell disorder: implications for counseling and psychotherapy. Hematol Rep (2010) 0.84
Characterization of the proximal ligand in the P420 form of inducible nitric oxide synthase. J Am Chem Soc (2009) 0.83
Cellular and biochemical actions of melatonin which protect against free radicals: role in neurodegenerative disorders. Curr Neuropharmacol (2008) 0.83
Nitric oxide-induced autoinhibition of neuronal nitric oxide synthase in the presence of the autoxidation-resistant pteridine 5-methyltetrahydrobiopterin. Biochem J (2000) 0.83
Parallel evolution of nitric oxide signaling: diversity of synthesis and memory pathways. Front Biosci (Landmark Ed) (2011) 0.83
Mechanisms of nitric oxide generation from nitroglycerin and endogenous sources during hypoxia in vivo. Br J Pharmacol (2002) 0.83