Published in Infect Immun on October 01, 2001
Antimicrobial mechanisms of phagocytes and bacterial evasion strategies. Nat Rev Microbiol (2009) 3.83
Salmonella pathogenicity island 2 mediates protection of intracellular Salmonella from reactive nitrogen intermediates. J Exp Med (2002) 3.31
The Salmonella kinase SteC targets the MAP kinase MEK to regulate the host actin cytoskeleton. Cell Host Microbe (2012) 1.66
Adaptive response of Yersinia pestis to extracellular effectors of innate immunity during bubonic plague. Proc Natl Acad Sci U S A (2006) 1.66
Comparison of gamma interferon-mediated antichlamydial defense mechanisms in human and mouse cells. Infect Immun (2006) 1.54
Flavohemoglobin Hmp protects Salmonella enterica serovar typhimurium from nitric oxide-related killing by human macrophages. Infect Immun (2002) 1.53
Nitric oxide metabolism in Neisseria meningitidis. J Bacteriol (2002) 1.49
Modulation of inducible nitric oxide synthase expression by the attaching and effacing bacterial pathogen citrobacter rodentium in infected mice. Infect Immun (2002) 1.29
Regulation of inducible nitric oxide synthase by aggresome formation. Proc Natl Acad Sci U S A (2005) 1.23
Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN-γ in a nitric oxide-dependent manner. J Immunol (2010) 1.21
Modulation of virulence by two acidified nitrite-responsive loci of Salmonella enterica serovar Typhimurium. Infect Immun (2003) 1.20
Macrophage migration inhibitory factor (MIF) plays a pivotal role in immunity against Salmonella typhimurium. Proc Natl Acad Sci U S A (2002) 1.18
Repression of SPI2 transcription by nitric oxide-producing, IFNgamma-activated macrophages promotes maturation of Salmonella phagosomes. J Exp Med (2005) 1.13
Post-translational modification and regulation of actin. Curr Opin Cell Biol (2012) 1.10
Nitric oxide and salmonella pathogenesis. Front Microbiol (2011) 1.06
Regulation of inducible nitric-oxide synthase by the SPRY domain- and SOCS box-containing proteins. J Biol Chem (2011) 0.92
N(2)O(3) enhances the nitrosative potential of IFNgamma-primed macrophages in response to Salmonella. Immunobiology (2007) 0.89
Antimicrobial Mechanisms of Macrophages and the Immune Evasion Strategies of Staphylococcus aureus. Pathogens (2015) 0.85
Analysis of nitric oxide-dependent antimicrobial actions in macrophages and mice. Methods Enzymol (2008) 0.84
Cellular localization of NLRP3 inflammasome. Protein Cell (2013) 0.83
Polarized distribution of inducible nitric oxide synthase regulates activity in intestinal epithelial cells. FEBS J (2005) 0.83
Binding of CAP70 to inducible nitric oxide synthase and implications for the vectorial release of nitric oxide in polarized cells. Mol Biol Cell (2007) 0.83
Tuberculosis: new aspects of an old disease. Int J Cell Biol (2011) 0.83
Codependent and independent effects of nitric oxide-mediated suppression of PhoPQ and Salmonella pathogenicity island 2 on intracellular Salmonella enterica serovar typhimurium survival. Infect Immun (2009) 0.81
Distinct intensity of host-pathogen interactions in Chlamydia psittaci- and Chlamydia abortus-infected chicken embryos. Infect Immun (2012) 0.79
Actin filaments-A target for redox regulation. Cytoskeleton (Hoboken) (2016) 0.78
Interferon-gamma and nitric oxide synthase 2 mediate the aggregation of resident adherent peritoneal exudate cells: implications for the host response to pathogens. PLoS One (2015) 0.75
Nitric oxide and macrophage function. Annu Rev Immunol (1997) 12.77
Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science (1992) 9.01
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature (1999) 8.50
Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation. J Cell Biol (1983) 5.73
Salmonella maintains the integrity of its intracellular vacuole through the action of SifA. EMBO J (2000) 5.27
Regulation of biosynthesis of nitric oxide. J Biol Chem (1994) 4.82
Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch Biochem Biophys (1991) 4.71
Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch Biochem Biophys (1992) 4.12
Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase. Science (2000) 4.12
Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. I. Effects on microbial killing by activated peritoneal macrophages in vitro. J Exp Med (2000) 3.91
Inducible nitric oxide synthase: what difference does it make? J Clin Invest (1997) 3.72
Periplasmic superoxide dismutase protects Salmonella from products of phagocyte NADPH-oxidase and nitric oxide synthase. Proc Natl Acad Sci U S A (1997) 3.71
Peroxynitrite reductase activity of bacterial peroxiredoxins. Nature (2000) 3.69
Mammalian nitric oxide synthases. Biochim Biophys Acta (1999) 3.55
Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta. J Exp Med (1993) 3.06
Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation. J Exp Med (1998) 2.89
Inhibition of macrophage phagosome-lysosome fusion by Salmonella typhimurium. Infect Immun (1991) 2.83
Inducible prophages contribute to Salmonella virulence in mice. Mol Microbiol (1999) 2.70
Bactericidal activity of peroxynitrite. Arch Biochem Biophys (1992) 2.61
Virulent Salmonella typhimurium has two periplasmic Cu, Zn-superoxide dismutases. Proc Natl Acad Sci U S A (1999) 2.44
Natural resistance to infection with intracellular pathogens: the Nramp1 protein is recruited to the membrane of the phagosome. J Exp Med (1997) 2.34
Molecular definition of distinct cytoskeletal structures involved in complement- and Fc receptor-mediated phagocytosis in macrophages. J Exp Med (1996) 2.25
Fusion of lysosomes with late endosomes produces a hybrid organelle of intermediate density and is NSF dependent. J Cell Biol (1998) 2.12
Reactive nitrogen intermediates and the pathogenesis of Salmonella and mycobacteria. Curr Opin Microbiol (2000) 1.73
Lysosomal enzyme trafficking between phagosomes, endosomes, and lysosomes in J774 macrophages. Enrichment of cathepsin H in early endosomes. J Biol Chem (1998) 1.67
Cytokine-treated human neutrophils contain inducible nitric oxide synthase that produces nitration of ingested bacteria. Proc Natl Acad Sci U S A (1996) 1.66
Nitric oxide and its role in apoptosis. Eur J Pharmacol (1998) 1.63
Regulation and subcellular location of nitrogen oxide synthases in RAW264.7 macrophages. Mol Pharmacol (1992) 1.63
Nitric oxide: cytotoxicity versus cytoprotection--how, why, when, and where? Nitric Oxide (1997) 1.52
Requirement for type 2 NO synthase for IL-12 signaling in innate immunity. Science (1999) 1.46
Isolation and characterization of early endosomes, late endosomes and terminal lysosomes: their role in protein degradation. J Cell Sci (1996) 1.35
Nitric oxide diffusion in membranes determined by fluorescence quenching. Arch Biochem Biophys (1996) 1.27
Nitric oxide signaling: would you believe that a simple free radical could be a second messenger, autacoid, paracrine substance, neurotransmitter, and hormone? Recent Prog Horm Res (1998) 1.23
Quo vadis: polarized membrane recycling in motility and phagocytosis. J Cell Biol (2000) 1.01
Regulation of the L-arginine-dependent and tetrahydrobiopterin-dependent biosynthesis of nitric oxide in murine macrophages. Eur J Biochem (1993) 0.98
Cytosolic and membrane-bound nitric oxide synthase. Jpn J Pharmacol (1991) 0.97
Chlorpromazine inhibits both the constitutive nitric oxide synthase and the induction of nitric oxide synthase after LPS challenge. Biochem Biophys Res Commun (1993) 0.93
Bactericidal agents generated by the peroxidase-catalyzed oxidation of para-hydroquinones. J Biol Chem (1985) 0.91
A commercial preparation of catalase inhibits nitric oxide production by activated murine macrophages: role of arginase. Infect Immun (2000) 0.81
Effect of pH and ATP on the equilibrium density of lysosomes. J Cell Physiol (1993) 0.77
Simultaneous identification of bacterial virulence genes by negative selection. Science (1995) 10.52
Identification of a virulence locus encoding a second type III secretion system in Salmonella typhimurium. Proc Natl Acad Sci U S A (1996) 6.42
Salmonella maintains the integrity of its intracellular vacuole through the action of SifA. EMBO J (2000) 5.27
Genes encoding putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2 are required for bacterial virulence and proliferation in macrophages. Mol Microbiol (1998) 5.07
A pneumococcal pilus influences virulence and host inflammatory responses. Proc Natl Acad Sci U S A (2006) 4.40
Identification of Staphylococcus aureus virulence genes in a murine model of bacteraemia using signature-tagged mutagenesis. Mol Microbiol (1997) 4.32
Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase. Science (2000) 4.12
A functional genomic analysis of type 3 Streptococcus pneumoniae virulence. Mol Microbiol (2001) 3.53
Use of randomly amplified polymorphic DNA markers to distinguish isolates of Aspergillus fumigatus. J Clin Microbiol (1992) 3.39
Use of mixed infections with Salmonella strains to study virulence genes and their interactions in vivo. Microbes Infect (2001) 3.13
Management of suspected Lyme borreliosis: experience from an outpatient parenteral antibiotic therapy service. QJM (2012) 2.76
An Aspergillus fumigatus alkaline protease mutant constructed by gene disruption is deficient in extracellular elastase activity. Mol Microbiol (1992) 2.59
Failure to thrive at the breast: an old problem revisited. Arch Dis Child (1977) 2.57
A Streptococcus pneumoniae pathogenicity island encoding an ABC transporter involved in iron uptake and virulence. Mol Microbiol (2001) 2.55
The detection of Aspergillus spp. by the polymerase chain reaction and its evaluation in bronchoalveolar lavage fluid. Am Rev Respir Dis (1993) 2.46
Influence of the Salmonella typhimurium pathogenicity island 2 type III secretion system on bacterial growth in the mouse. Infect Immun (1999) 2.38
Gene transfer system for the phytopathogenic fungus Ustilago maydis. Proc Natl Acad Sci U S A (1988) 2.36
pH-dependent secretion of SseB, a product of the SPI-2 type III secretion system of Salmonella typhimurium. Mol Microbiol (1999) 2.29
In vivo genetic analysis of bacterial virulence. Annu Rev Microbiol (1999) 2.23
Effect of storage and heat on antimicrobial proteins in human milk. Arch Dis Child (1978) 2.09
RrgA is a pilus-associated adhesin in Streptococcus pneumoniae. Mol Microbiol (2007) 2.01
Functional analysis of ssaJ and the ssaK/U operon, 13 genes encoding components of the type III secretion apparatus of Salmonella Pathogenicity Island 2. Mol Microbiol (1997) 1.99
Increased expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in the airway epithelium of asthmatic subjects and regulation by corticosteroid treatment. Thorax (2001) 1.95
Intracellular replication of Salmonella typhimurium strains in specific subsets of splenic macrophages in vivo. Cell Microbiol (2001) 1.88
Immunization with components of two iron uptake ABC transporters protects mice against systemic Streptococcus pneumoniae infection. Infect Immun (2001) 1.81
Analysis of the boundaries of Salmonella pathogenicity island 2 and the corresponding chromosomal region of Escherichia coli K-12. J Bacteriol (1997) 1.81
Outcome of Burkholderia (Pseudomonas) cepacia colonisation in children with cystic fibrosis following a hospital outbreak. Thorax (1995) 1.78
Maternal narcotic abuse and the newborn. Arch Dis Child (1988) 1.66
The alkaline protease of Aspergillus fumigatus is not a virulence determinant in two murine models of invasive pulmonary aspergillosis. Infect Immun (1993) 1.63
Neutrophils enhance expression of inducible nitric oxide synthase in human normal but not cystic fibrosis bronchial epithelial cells. J Pathol (2000) 1.57
Signature-tagged and directed mutagenesis identify PABA synthetase as essential for Aspergillus fumigatus pathogenicity. Mol Microbiol (2000) 1.52
Mutations in Salmonella pathogenicity island 2 (SPI2) genes affecting transcription of SPI1 genes and resistance to antimicrobial agents. J Bacteriol (1998) 1.52
Virulence of Aspergillus fumigatus double mutants lacking restriction and an alkaline protease in a low-dose model of invasive pulmonary aspergillosis. Infect Immun (1994) 1.44
Remodelling of the actin cytoskeleton is essential for replication of intravacuolar Salmonella. Cell Microbiol (2001) 1.43
Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite. Lab Invest (1996) 1.35
Cyclooxygenase-2 is widely expressed in atherosclerotic lesions affecting native and transplanted human coronary arteries and colocalizes with inducible nitric oxide synthase and nitrotyrosine particularly in macrophages. Arterioscler Thromb Vasc Biol (1999) 1.35
A role for the PhoP/Q regulon in inhibition of fusion between lysosomes and Salmonella-containing vacuoles in macrophages. Cell Microbiol (2001) 1.34
Lack of inducible nitric oxide synthase in bronchial epithelium: a possible mechanism of susceptibility to infection in cystic fibrosis. J Pathol (1998) 1.34
Protein blotting: detection of proteins with colloidal gold, and of glycoproteins and lectins with biotin-conjugated and enzyme probes. Anal Biochem (1985) 1.28
Molecular epidemiological study of invasive pulmonary aspergillosis in a renal transplantation unit. Eur J Clin Microbiol Infect Dis (1994) 1.21
Isolation of metabolic genes and demonstration of gene disruption in the phytopathogenic fungus Ustilago maydis. Gene (1989) 1.16
The Aspergillus fumigatus chsC and chsG genes encode class III chitin synthases with different functions. Mol Microbiol (1996) 1.13
13Carbon mixed triglyceride breath test and pancreatic enzyme supplementation in cystic fibrosis. Arch Dis Child (1997) 1.12
Identification and analysis of bacterial virulence genes in vivo. Philos Trans R Soc Lond B Biol Sci (2000) 1.10
Streptococcal pyrogenic exotoxin A release, distribution, and role in a murine model of fasciitis and multiorgan failure due to Streptococcus pyogenes. J Infect Dis (1996) 1.08
Immunochemical localization of inducible nitric oxide synthase in endotoxin-treated rats. Lab Invest (1994) 1.07
The Ustilago maydis nar1 gene encoding nitrate reductase activity: sequence and transcriptional regulation. Gene (1993) 1.06
The role of the Aspergillus fumigatus areA gene in invasive pulmonary aspergillosis. Mol Gen Genet (1998) 1.05
Aspergillus fumigatus chsE: a gene related to CHS3 of Saccharomyces cerevisiae and important for hyphal growth and conidiophore development but not pathogenicity. Fungal Genet Biol (1997) 1.04
In vivo genetic analysis indicates that PhoP-PhoQ and the Salmonella pathogenicity island 2 type III secretion system contribute independently to Salmonella enterica serovar Typhimurium virulence. Infect Immun (2001) 1.04
Cell wall biogenesis in a double chitin synthase mutant (chsG-/chsE-) of Aspergillus fumigatus. Fungal Genet Biol (2003) 1.01
The cytokine responsive vascular smooth muscle cell enhancer of inducible nitric oxide synthase. Activation by nuclear factor-kappa B. J Biol Chem (1995) 1.01
Virulence studies of Aspergillus nidulans mutants requiring lysine or p-aminobenzoic acid in invasive pulmonary aspergillosis. Infect Immun (1994) 1.00
A multigene family related to chitin synthase genes of yeast in the opportunistic pathogen Aspergillus fumigatus. Mol Gen Genet (1995) 0.98
Cytokine-stimulated expression of inducible nitric oxide synthase by mouse, rat, and human osteoblast-like cells and its functional role in osteoblast metabolic activity. Endocrinology (1995) 0.96
Growth and milk intake of normal infants. Arch Dis Child (1978) 0.96
Cloning and characterization of chsD, a chitin synthase-like gene of Aspergillus fumigatus. FEMS Microbiol Lett (1996) 0.94
Construction and pathogenicity of Aspergillus fumigatus mutants that do not produce the ribotoxin restrictocin. Mol Microbiol (1993) 0.93
Bacterial superantigen-induced human lymphocyte responses are nitric oxide dependent and mediated by IL-12 and IFN-gamma. J Immunol (1996) 0.92
Proinflammatory cytokine production by human peripheral blood mononuclear cells stimulated with cell-free supernatants of Viridans streptococci. Cytokine (1996) 0.92
Insertional mutagenesis of Aspergillus fumigatus. Mol Gen Genet (1998) 0.91
Pseudomembranous colitis in association with Henoch Schonlein purpura. Scott Med J (1988) 0.90
Validation of the in vitro gastrointestinal (IVG) method to estimate relative bioavailable lead in contaminated soils. J Environ Qual (2004) 0.90
Molecular genetic approaches for the study of virulence in both pathogenic bacteria and fungi. Microbiology (1996) 0.89
The role of nitric oxide in experimental murine sepsis due to pyrogenic exotoxin A-producing Streptococcus pyogenes. Infect Immun (1997) 0.88
Detection of gene-disruption events in Aspergillus transformants by polymerase chain reaction direct from conidiospores. Curr Genet (1993) 0.87
Congenital cytomegalovirus infection after maternal renal transplantation. Lancet (1975) 0.86
Effects of short-term heat stress on endophytic ergot alkaloid-induced alterations in rat hepatic gene expression. J Anim Sci (2009) 0.85
Population pharmacokinetics of rectal theophylline in neonates. Ther Drug Monit (1991) 0.85
Insertional mutagenesis of pathogenic fungi. Curr Opin Microbiol (1998) 0.85
Differences in the shedding of soluble TNF receptors between endotoxin-sensitive and endotoxin-resistant mice in response to lipopolysaccharide or live bacterial challenge. J Immunol (1995) 0.84
Nutrition and early growth of preterm infants. Early Hum Dev (1978) 0.84
Clinical course of patients with cystic fibrosis presenting with meconium ileus. Br J Surg (1997) 0.84
Systemic cytokine response to hepatic resections under total vascular exclusion. Eur J Surg (1998) 0.83
Coexpressed nitric oxide synthase and apical beta(1) integrins influence tubule cell adhesion after cytokine-induced injury. J Am Soc Nephrol (2001) 0.82
The evolution of liver disease in cystic fibrosis. Arch Dis Child (1999) 0.82
Microvillous inclusion disease: an evolving condition. J Pediatr Gastroenterol Nutr (2000) 0.82
Handling of death in special care nurseries and parental grief. Br Med J (Clin Res Ed) (1984) 0.81
Comparison of virulence between clinical and environmental isolates of Aspergillus fumigatus. Eur J Clin Microbiol Infect Dis (1998) 0.80
Expression of inducible nitric oxide synthase and formation of peroxynitrite in posttransplant obliterative bronchiolitis. J Heart Lung Transplant (1998) 0.80
Probing the active site of mitogillin, a fungal ribotoxin. Mol Microbiol (1998) 0.80
The Ustilago maydis pyr3 gene: sequence and transcriptional analysis. Gene (1992) 0.79
Equine endometrial fibrosis correlates with 11beta-HSD2, TGF-beta1 and ACE activities. Mol Cell Endocrinol (2006) 0.78
New endocrine agents for the treatment of breast cancer. Recent Results Cancer Res (1993) 0.78
Use of different levels of ground endophyte-infected tall fescue seed during heat stress to separate characteristics of fescue toxicosis. J Anim Sci (2012) 0.78
Evolution of transcription-regulating proteins: caveat lector! Gene (1997) 0.77
Meconium ileus: a review 1972-1990. Br J Surg (1992) 0.77
13C and H2 breath tests to study extent and site of starch digestion in children with cystic fibrosis. J Pediatr Gastroenterol Nutr (1999) 0.77
Inflammatory bowel disease in Scottish children. Health Bull (Edinb) (1999) 0.77
Effect of adhesion on inducible nitric oxide synthase (iNOS) production in purified human neutrophils. Clin Exp Immunol (2001) 0.77
Viridans streptococcal bacteraemia: a clinical survey. QJM (1995) 0.77
An annular erythema of infancy. Arch Dermatol (1987) 0.76
Ceftriaxone-related agranulocytosis during outpatient parenteral antibiotic therapy. J Antimicrob Chemother (2010) 0.75
Immunoreactive trypsinogen concentrations in infants with meconium ileus. BMJ (1991) 0.75
Letter of response to Stricker et al. QJM (2012) 0.75
Melatonin state in Mendenhall's syndrome. Arch Dis Child (1988) 0.75
AIDS related cholangitis. Scott Med J (1995) 0.75
Porencephaly and optic hypoplasia in neonatal isoimmune thrombocytopenia. Arch Dis Child (1989) 0.75
Retrobulbar block: a review for the clinician. AANA J (1991) 0.75
Detection of intravascularly located epidural catheter. Anesth Analg (1993) 0.75