PubRank

H J Kung

Author PubWeight™ 187.91‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mapping unintegrated avian sarcoma virus DNA: termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA. Cell 1978 13.33
2 Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites. Cell 1978 7.46
3 Covalently closed circular DNA of avian sarcoma virus: purification from nuclei of infected quail tumor cells and measurement by electron microscopy and gel electrophoresis. J Mol Biol 1976 4.65
4 Kinetics of synthesis, structure and purification of avian sarcoma virus-specific DNA made in the cytoplasm of acutely infected cells. J Mol Biol 1978 4.04
5 Activation of the cellular oncogene c-erbB by LTR insertion: molecular basis for induction of erythroblastosis by avian leukosis virus. Cell 1983 3.45
6 On the mechanism of retrovirus-induced avian lymphoid leukosis: deletion and integration of the proviruses. Proc Natl Acad Sci U S A 1981 3.30
7 RD-114, baboon, and woolly monkey viral RNA's compared in size and structure. Cell 1976 3.20
8 Interaction between retroviral U5 RNA and the T psi C loop of the tRNA(Trp) primer is required for efficient initiation of reverse transcription. J Virol 1992 3.06
9 c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor. Cell 1985 3.00
10 An electron microscope study of Sindbis virus RNA. Cold Spring Harb Symp Quant Biol 1974 2.99
11 Structure, subunit composition, and molecular weight of RD-114 RNA. J Virol 1975 2.66
12 Electron microscope studies of tumor virus RNA. Cold Spring Harb Symp Quant Biol 1975 2.30
13 Kaposi's sarcoma-associated herpesvirus encodes a bZIP protein with homology to BZLF1 of Epstein-Barr virus. J Virol 1999 2.24
14 CWR22: the first human prostate cancer xenograft with strongly androgen-dependent and relapsed strains both in vivo and in soft agar. Cancer Res 1996 2.18
15 Characterization of DNA complementary to nucleotide sequences adjacent to poly(A) at the 3'-terminus of the avian sarcoma virus genome. Virology 1977 2.18
16 Characterization of DNA complementary to nucleotide sequences at the 5'-terminus of the avian sarcoma virus genome. Virology 1977 2.16
17 Specific integration of REV proviruses in avian bursal lymphomas. Nature 1981 2.11
18 Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells. Nature 1998 2.08
19 Activated type I phosphatidylinositol kinase is associated with the epidermal growth factor (EGF) receptor following EGF stimulation. Proc Natl Acad Sci U S A 1990 1.95
20 Evidence of independent origin of multiple tumors from patients with prostate cancer. J Natl Cancer Inst 1998 1.81
21 Marek disease virus encodes a basic-leucine zipper gene resembling the fos/jun oncogenes that is highly expressed in lymphoblastoid tumors. Proc Natl Acad Sci U S A 1992 1.78
22 CWR22: androgen-dependent xenograft model derived from a primary human prostatic carcinoma. Cancer Res 1994 1.77
23 Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII). Biochem J 1997 1.72
24 Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells. Proc Natl Acad Sci U S A 1998 1.70
25 Altered expression of RET proto-oncogene product in prostatic intraepithelial neoplasia and prostate cancer. J Natl Cancer Inst 1998 1.68
26 Synthesis of plus strands of retroviral DNA in cells infected with avian sarcoma virus and mouse mammary tumor virus. J Virol 1981 1.67
27 A tyrosine kinase profile of prostate carcinoma. Proc Natl Acad Sci U S A 1996 1.67
28 c-erbB activation in avian leukosis virus-induced erythroblastosis: clustered integration sites and the arrangement of provirus in the c-erbB alleles. Proc Natl Acad Sci U S A 1985 1.62
29 Signaling network of the Btk family kinases. Oncogene 2000 1.58
30 The complete unique long sequence and the overall genomic organization of the GA strain of Marek's disease virus. Proc Natl Acad Sci U S A 2000 1.55
31 Tumor induction by direct injection of cloned v-src DNA into chickens. Proc Natl Acad Sci U S A 1983 1.53
32 Hierarchical cleavage of focal adhesion kinase by caspases alters signal transduction during apoptosis of intestinal epithelial cells. Gastroenterology 2001 1.52
33 Neuropeptide-induced androgen independence in prostate cancer cells: roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase. Mol Cell Biol 2001 1.46
34 Human cellular src gene: nucleotide sequence and derived amino acid sequence of the region coding for the carboxy-terminal two-thirds of pp60c-src. Mol Cell Biol 1985 1.46
35 Size, subunit composition, and secondary structure of the Friend virus genome. J Virol 1976 1.45
36 Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation. Mol Cell Biol 2000 1.44
37 Nucleolar and nuclear localization properties of a herpesvirus bZIP oncoprotein, MEQ. J Virol 1997 1.43
38 DNA sequence encoding the amino-terminal region of the human c-src protein: implications of sequence divergence among src-type kinase oncogenes. Mol Cell Biol 1987 1.41
39 Transforming potential of the herpesvirus oncoprotein MEQ: morphological transformation, serum-independent growth, and inhibition of apoptosis. J Virol 1998 1.39
40 MCF-10A-NeoST: a new cell system for studying cell-ECM and cell-cell interactions in breast cancer. Clin Cancer Res 2001 1.36
41 Marek's disease virus (MDV) encodes an interleukin-8 homolog (vIL-8): characterization of the vIL-8 protein and a vIL-8 deletion mutant MDV. J Virol 2001 1.34
42 The identification of monoclonality in human aberrant crypt foci. Cancer Res 1999 1.34
43 Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain. Nat Cell Biol 2001 1.34
44 ErbB kinases and NDF signaling in human prostate cancer cells. Oncogene 1997 1.28
45 Etk/Bmx tyrosine kinase activates Pak1 and regulates tumorigenicity of breast cancer cells. J Biol Chem 2001 1.27
46 Structural analysis and transcriptional mapping of the Marek's disease virus gene encoding pp38, an antigen associated with transformed cells. J Virol 1991 1.26
47 Orientation and position of avian leukosis virus DNA relative to the cellular oncogene c-myc in B-lymphoma tumors of highly susceptible 15I5 X 7(2) chickens. J Virol 1982 1.24
48 Retrovirus insertion into herpesvirus in vitro and in vivo. Proc Natl Acad Sci U S A 1992 1.22
49 MST4, a new Ste20-related kinase that mediates cell growth and transformation via modulating ERK pathway. Oncogene 2001 1.22
50 Isolation and structural mapping of a human c-src gene homologous to the transforming gene (v-src) of Rous sarcoma virus. J Virol 1985 1.20
51 A complete description of the EGF-receptor exon structure: implication in oncogenic activation and domain evolution. Oncogene 1993 1.20
52 Transactivation activity of Meq, a Marek's disease herpesvirus bZIP protein persistently expressed in latently infected transformed T cells. J Virol 1995 1.19
53 Origin and prognostic value of circulating KRAS mutations in lung cancer patients. Cancer Lett 2007 1.17
54 Rous-associated virus 1-induced erythroleukemic cells exhibit a weakly transformed phenotype in vitro and release c-erbB-containing retroviruses unable to transform fibroblasts. J Virol 1986 1.16
55 Mitogenic signals and transforming potential of Nyk, a newly identified neural cell adhesion molecule-related receptor tyrosine kinase. Mol Cell Biol 1995 1.13
56 Molecular characterization of three erbB transducing viruses generated during avian leukosis virus-induced erythroleukemia: extensive internal deletion near the kinase domain activates the fibrosarcoma- and hemangioma-inducing potentials of erbB. J Virol 1988 1.12
57 Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa. Int J Cancer 1999 1.12
58 Mechanism of c-erbB transduction: newly released transducing viruses retain poly(A) tracts of erbB transcripts and encode C-terminally intact erbB proteins. J Virol 1988 1.12
59 Retroviral insertions into a herpesvirus are clustered at the junctions of the short repeat and short unique sequences. Proc Natl Acad Sci U S A 1993 1.12
60 Hormonal regulation of the gene for the type C ecotropic retrovirus receptor in rat liver cells. J Virol 1994 1.08
61 B-lymphoma induction by reticuloendotheliosis virus: characterization of a mutated chicken syncytial virus provirus involved in c-myc activation. J Virol 1987 1.07
62 EGF-R as a hemopoietic growth factor receptor: the c-erbB product is present in chicken erythrocytic progenitors and controls their self-renewal. Cell 1991 1.07
63 Proviral-activated c-erbB is leukemogenic but not sarcomagenic: characterization of a replication-competent retrovirus containing the activated c-erbB. J Virol 1988 1.07
64 Identification of the major autophosphorylation sites of Nyk/Mer, an NCAM-related receptor tyrosine kinase. J Biol Chem 1996 1.05
65 c-erbB activation in avian leukosis virus-induced erythroblastosis: multiple epidermal growth factor receptor mRNAs are generated by alternative RNA processing. Mol Cell Biol 1986 1.04
66 Potential role of the src gene product in inhibition of gap-junctional communication in NIH/3T3 cells. Proc Natl Acad Sci U S A 1985 1.04
67 Tissue-specific transformation by epidermal growth factor receptor: a single point mutation within the ATP-binding pocket of the erbB product increases its intrinsic kinase activity and activates its sarcomagenic potential. Proc Natl Acad Sci U S A 1990 1.04
68 MEQ and V-IL8: cellular genes in disguise? Acta Virol 2000 1.03
69 Tyrosine kinases and gastric cancer. Oncogene 2000 1.03
70 Extensive homology exists between Marek disease herpesvirus and its vaccine virus, herpesvirus of turkeys. Proc Natl Acad Sci U S A 1984 1.03
71 Amplification and rearrangement of the Kirsten ras oncogene in virus-transformed BALB/c 3T3 cells during malignant tumor progression. Proc Natl Acad Sci U S A 1987 1.02
72 A flavonoid antioxidant, silymarin, inhibits activation of erbB1 signaling and induces cyclin-dependent kinase inhibitors, G1 arrest, and anticarcinogenic effects in human prostate carcinoma DU145 cells. Cancer Res 1998 1.02
73 Integration of multiple chicken retroviruses into multiple chicken herpesviruses: herpesviral gD as a common target of integration. Virology 1994 1.02
74 Kinase activation of the non-receptor tyrosine kinase Etk/BMX alone is sufficient to transactivate STAT-mediated gene expression in salivary and lung epithelial cells. J Biol Chem 1999 1.02
75 Novel DNA binding specificities of a putative herpesvirus bZIP oncoprotein. J Virol 1996 1.01
76 tie-1 protein tyrosine kinase: a novel independent prognostic marker for gastric cancer. Clin Cancer Res 1999 1.00
77 Disease tropism of c-erbB: effects of carboxyl-terminal tyrosine and internal mutations on tissue-specific transformation. Proc Natl Acad Sci U S A 1989 0.99
78 In vitro transcription analysis of the viral promoter involved in c-myc activation in chicken B lymphomas: detection and mapping of two RNA initiation sites within the reticuloendotheliosis virus long terminal repeat. J Virol 1985 0.99
79 Marek's disease herpesvirus transforming protein MEQ: a c-Jun analogue with an alternative life style. Virus Genes 2000 0.98
80 Avian lymphoid leukosis virus infection and DNA integration in the preleukotic bursal tissues: a comparative study of susceptible and resistant lines. Virology 1982 0.97
81 Growth hormone interacts with the Marek's disease virus SORF2 protein and is associated with disease resistance in chicken. Proc Natl Acad Sci U S A 2001 0.96
82 A new defective retroviral vector system based on the Bryan strain of Rous sarcoma virus. Virology 1993 0.96
83 Proviral insertional activation of c-erbB: differential processing of the protein products arising from two alternate transcripts. Mol Cell Biol 1988 0.96
84 C-erbB and the epidermal growth-factor receptor: a molecule with dual identity. Biochim Biophys Acta 1989 0.96
85 Transcriptional interaction between retroviral long terminal repeats (LTRs): mechanism of 5' LTR suppression and 3' LTR promoter activation of c-myc in avian B-cell lymphomas. J Virol 1992 0.95
86 An alternatively processed mRNA from the avian c-erbB gene encodes a soluble, truncated form of the receptor that can block ligand-dependent transformation. Mol Cell Biol 1992 0.95
87 Identification and characterization of dimeric and trimeric circular forms of avian sarcoma virus-specific DNA. Virology 1980 0.95
88 Synthesis, processing, and secretion of the Marek's disease herpesvirus A antigen glycoprotein. J Virol 1986 0.95
89 Retroviral insertional mutagenesis of a herpesvirus: a Marek's disease virus mutant attenuated for oncogenicity but not for immunosuppression or in vivo replication. Avian Dis 1997 0.94
90 Protein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinases. J Biol Chem 2000 0.94
91 Etk/Bmx, a PH-domain containing tyrosine kinase, protects prostate cancer cells from apoptosis induced by photodynamic therapy or thapsigargin. Oncogene 1999 0.94
92 Structure and molecular length of the large subunits of RD-114 viral RNA. J Virol 1974 0.93
93 Molecular characterization of Marek's disease herpesvirus B antigen. J Virol 1986 0.92
94 Synthesis, structure, and integration of the DNA of RNA tumor viruses. Cold Spring Harb Symp Quant Biol 1979 0.92
95 Axl-gas6 interaction counteracts E1A-mediated cell growth suppression and proapoptotic activity. Mol Cell Biol 1999 0.92
96 Dissecting the activating mutations in v-erbB of avian erythroblastosis virus strain R. J Virol 1991 0.92
97 Functional interactions between herpesvirus oncoprotein MEQ and cell cycle regulator CDK2. J Virol 1999 0.91
98 Proteolytic activation of ETK/Bmx tyrosine kinase by caspases. J Biol Chem 2001 0.91
99 C-myc activation in an unusual retrovirus-induced avian T-lymphoma resembling Marek's disease: proviral insertion 5' of exon one enhances the expression of an intron promoter. Oncogene Res 1987 0.91
100 Insertional activation of c-myc by reticuloendotheliosis virus in chicken B lymphoma: nonrandom distribution and orientation of the proviruses. J Virol 1985 0.90
101 Retroviral insertional activation in a herpesvirus: transcriptional activation of US genes by an integrated long terminal repeat in a Marek's disease virus clone. J Virol 1996 0.90
102 Construction and characterization of a H19 epitope point mutant of MDV CVI988/Rispens strain. Acta Virol 2000 0.89
103 Identification of the gene encoding Marek's disease herpesvirus A antigen. J Virol 1987 0.89
104 Retrovirus insertion into herpesvirus: characterization of a Marek's disease virus harboring a solo LTR. Virology 1993 0.89
105 A minor tyrosine phosphorylation site located within the CAIN domain plays a critical role in regulating tissue-specific transformation by erbB kinase. J Virol 1995 0.88
106 Native avian c-erbB gene expresses a secreted protein product corresponding to the ligand-binding domain of the receptor. Proc Natl Acad Sci U S A 1991 0.87
107 Transient expression analysis of the reticuloendotheliosis virus long terminal repeat element. Nucleic Acids Res 1989 0.87
108 An IgM-producing B lymphoblastoid cell line established from lymphomas induced by a non-defective reticuloendotheliosis virus. J Gen Virol 1982 0.86
109 Modulation of erbB kinase activity and oncogenic potential by single point mutations in the glycine loop of the catalytic domain. Mol Cell Biol 1994 0.86
110 Purification of genomic sized herpesvirus DNA using pulse-field electrophoresis. J Virol Methods 1990 0.85
111 Tissue-specific transformation by oncogenic mutants of epidermal growth factor receptor. Crit Rev Oncog 1994 0.85
112 Transformation of chicken embryo fibroblasts by direct DNA transfection of single oncogenes: comparative analyses of src, erbB, myc, and ras. J Virol 1990 0.84
113 Protein-tyrosine kinase and protein-serine/threonine kinase expression in human gastric cancer cell lines. J Biomed Sci 1998 0.83
114 Retrovirus insertion into herpesviruses. Trends Microbiol 1994 0.83
115 Identification of protein kinases dysregulated in CD4(+) T cells in pathogenic versus apathogenic simian immunodeficiency virus infection. J Virol 2001 0.83
116 Identification and characterization of a Marek's disease virus gene encoding DNA polymerase. Virus Res 1995 0.83
117 The molecular basis of avian retrovirus-induced leukemogenesis. Haematol Blood Transfus 1981 0.81
118 Molecular indications for in vivo integration of the avian leukosis virus, subgroup J-long terminal repeat into the Marek's disease virus in experimentally dually-infected chickens. Virus Genes 2002 0.80
119 Resistance to transformation by insertionally activated c-erbB is a dominant phenotype in fibroblasts. Virology 1995 0.79
120 Digital cloning: identification of human cDNAs homologous to novel kinases through expressed sequence tag database searching. J Biomed Sci 1998 0.79
121 Retrotransposition and herpesvirus evolution. Virus Genes 1995 0.79
122 An EGF-pseudomonas exotoxin A recombinant protein with a deletion in toxin binding domain specifically kills EGF receptor bearing cells. Protein Eng 1993 0.78
123 Molecular biology of prostate carcinogenesis. Crit Rev Oncol Hematol 1999 0.78
124 Coordinate alteration of pp60c-src abundance and c-src RNA expression in human neuroblastoma variants. Oncogene 1989 0.78
125 Tyrosine kinase expression profiles of chicken erythro-progenitor cells and oncogene-transformed erythroblasts. J Biomed Sci 1998 0.78
126 KFC, a Ste20-like kinase with mitogenic potential and capability to activate the SAPK/JNK pathway. Oncogene 2000 0.77
127 The effect of epidermal growth factor receptor (EGFR) expression on in vivo growth of rat C6 glioma cells. Leukemia 1995 0.77
128 Stepwise transformation of astrocytes by simian virus 40 large T antigen and epidermal growth factor receptor overexpression. Cell Growth Differ 1996 0.77
129 Disease specificity of kinase domains: the src-encoded catalytic domain converts erbB into a sarcoma oncogene. Proc Natl Acad Sci U S A 1995 0.76
130 Structures of unintegrated and integrated forms of the deoxyribonucleic acid of ribonucleic acid tumour viruses. Biochem Soc Symp 1979 0.75
131 Cloning of a putative chicken MHC class II alpha chain gene. Prog Clin Biol Res 1987 0.75
132 Avian leukemias and lymphomas: interplay between retroviruses and herpesviruses. Leukemia 1997 0.75
133 Pseudomonas exotoxin A-epidermal growth factor (EGF) mutant chimeric protein as an indicator for identifying amino acid residues important in EGF-receptor interaction. J Biol Chem 1992 0.75