Published in Am J Hum Genet on July 01, 1999
Inference of population structure using multilocus genotype data. Genetics (2000) 147.76
Association mapping in structured populations. Am J Hum Genet (2000) 16.79
Genetic mapping in human disease. Science (2008) 15.12
Linkage disequilibrium in humans: models and data. Am J Hum Genet (2001) 14.97
Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci U S A (2001) 9.42
Trimming, weighting, and grouping SNPs in human case-control association studies. Genome Res (2001) 9.41
Interpreting principal component analyses of spatial population genetic variation. Nat Genet (2008) 8.49
New approaches to population stratification in genome-wide association studies. Nat Rev Genet (2010) 7.97
Informativeness of genetic markers for inference of ancestry. Am J Hum Genet (2003) 6.90
Ascertainment bias in studies of human genome-wide polymorphism. Genome Res (2005) 6.63
A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. PLoS Genet (2008) 5.85
Genetic analysis of case/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease. Genome Res (2001) 5.78
Revealing the architecture of gene regulation: the promise of eQTL studies. Trends Genet (2008) 5.78
Accounting for unmeasured population substructure in case-control studies of genetic association using a novel latent-class model. Am J Hum Genet (2001) 5.66
Coalescent-based association mapping and fine mapping of complex trait loci. Genetics (2004) 5.26
Genetics in geographically structured populations: defining, estimating and interpreting F(ST). Nat Rev Genet (2009) 5.23
Population structure in admixed populations: effect of admixture dynamics on the pattern of linkage disequilibrium. Am J Hum Genet (2000) 4.74
Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes. Am J Hum Genet (2004) 4.44
Social supports and serotonin transporter gene moderate depression in maltreated children. Proc Natl Acad Sci U S A (2004) 4.42
A simple and improved correction for population stratification in case-control studies. Am J Hum Genet (2007) 4.29
A general framework for multiple testing dependence. Proc Natl Acad Sci U S A (2008) 4.27
Confounding from cryptic relatedness in case-control association studies. PLoS Genet (2005) 3.61
Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological research. Am J Public Health (2005) 3.50
Genome-wide association scans identified CTNNBL1 as a novel gene for obesity. Hum Mol Genet (2008) 3.24
A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. Nat Genet (2005) 3.15
Matching strategies for genetic association studies in structured populations. Am J Hum Genet (2004) 3.13
Genetics of Kidneys in Diabetes (GoKinD) study: a genetics collection available for identifying genetic susceptibility factors for diabetic nephropathy in type 1 diabetes. J Am Soc Nephrol (2006) 3.12
Japanese population structure, based on SNP genotypes from 7003 individuals compared to other ethnic groups: effects on population-based association studies. Am J Hum Genet (2008) 3.12
Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia. Proc Natl Acad Sci U S A (2002) 3.11
Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. Am J Hum Genet (2000) 3.06
A unified association analysis approach for family and unrelated samples correcting for stratification. Am J Hum Genet (2008) 3.00
Genome-wide and candidate gene association study of cigarette smoking behaviors. PLoS One (2009) 3.00
Logistic regression protects against population structure in genetic association studies. Genome Res (2005) 2.94
Haplotype block structure and its applications to association studies: power and study designs. Am J Hum Genet (2002) 2.88
Case-control association testing in the presence of unknown relationships. Genet Epidemiol (2009) 2.63
Population structure and its effect on haplotype diversity and linkage disequilibrium surrounding the xa5 locus of rice (Oryza sativa L.). Genetics (2003) 2.58
A genomewide association study of skin pigmentation in a South Asian population. Am J Hum Genet (2007) 2.58
Reliability of genomic predictions across multiple populations. Genetics (2009) 2.46
Are transporter genes other than the chloroquine resistance locus (pfcrt) and multidrug resistance gene (pfmdr) associated with antimalarial drug resistance? Antimicrob Agents Chemother (2005) 2.44
Genome-wide association of lipid-lowering response to statins in combined study populations. PLoS One (2010) 2.43
Testing for population subdivision and association in four case-control studies. Am J Hum Genet (2002) 2.26
Comparison of three methods to estimate genetic ancestry and control for stratification in genetic association studies among admixed populations. Hum Genet (2005) 2.19
Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder. Neuropsychopharmacology (2010) 2.16
A functional promoter polymorphism in monocyte chemoattractant protein-1 is associated with increased susceptibility to pulmonary tuberculosis. J Exp Med (2005) 2.15
Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records. Genet Med (2010) 2.09
Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations. Am J Respir Cell Mol Biol (2005) 2.08
Analysis of population structure: a unifying framework and novel methods based on sparse factor analysis. PLoS Genet (2010) 2.06
Complexity and power in case-control association studies. Am J Hum Genet (2001) 2.05
Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations. Arch Gen Psychiatry (2009) 1.97
Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth. J Neurosci (2008) 1.96
Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family. Proc Natl Acad Sci U S A (2004) 1.95
Association between two mu-opioid receptor gene (OPRM1) haplotype blocks and drug or alcohol dependence. Hum Mol Genet (2006) 1.93
Review and evaluation of methods correcting for population stratification with a focus on underlying statistical principles. Hum Hered (2008) 1.92
A general population-genetic model for the production by population structure of spurious genotype-phenotype associations in discrete, admixed or spatially distributed populations. Genetics (2006) 1.92
Novel polymorphisms in the myosin light chain kinase gene confer risk for acute lung injury. Am J Respir Cell Mol Biol (2006) 1.88
The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort. Biol Psychiatry (2008) 1.86
Methodological Considerations in Studying Centenarians: Lessons Learned From the Georgia Centenarian Studies. Annu Rev Gerontol Geriatr (2007) 1.85
"Are we there yet?": Deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits. Am J Hum Genet (2003) 1.82
Genetical genomic determinants of alcohol consumption in rats and humans. BMC Biol (2009) 1.81
Genetics, transcriptomics, and proteomics of Alzheimer's disease. J Clin Psychiatry (2006) 1.81
Sample size requirements to detect gene-environment interactions in genome-wide association studies. Genet Epidemiol (2011) 1.78
Distinctive genetic signatures in the Libyan Jews. Proc Natl Acad Sci U S A (2001) 1.78
Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence. Biol Psychiatry (2011) 1.76
Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas. PLoS Genet (2012) 1.74
Genome-wide association studies and beyond. Annu Rev Public Health (2010) 1.73
Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels. Hum Genomics (2004) 1.71
Prospects for association mapping in classical inbred mouse strains. Genetics (2007) 1.71
Chromogranin A polymorphisms are associated with hypertensive renal disease. J Am Soc Nephrol (2008) 1.68
Epistatic interactions. Stat Appl Genet Mol Biol (2010) 1.66
Linkage disequilibrium analysis of biallelic DNA markers, human quantitative trait loci, and threshold-defined case and control subjects. Am J Hum Genet (2000) 1.65
Consistent long-range linkage disequilibrium generated by admixture in a Bantu-Semitic hybrid population. Am J Hum Genet (2000) 1.65
Genetic model selection in two-phase analysis for case-control association studies. Biostatistics (2007) 1.64
Confounding underlies the apparent month of birth effect in multiple sclerosis. Ann Neurol (2013) 1.62
A common genetic variant in the neurexin superfamily member CNTNAP2 is associated with increased risk for selective mutism and social anxiety-related traits. Biol Psychiatry (2010) 1.62
On the adjustment for covariates in genetic association analysis: a novel, simple principle to infer direct causal effects. Genet Epidemiol (2009) 1.62
Influence of leukotriene pathway polymorphisms on response to montelukast in asthma. Am J Respir Crit Care Med (2005) 1.58
Modification of the association between serotonin transporter genotype and risk of posttraumatic stress disorder in adults by county-level social environment. Am J Epidemiol (2009) 1.58
Genetic ancestry and risk of breast cancer among U.S. Latinas. Cancer Res (2008) 1.58
Admixture mapping of male nuptial colour and body shape in a recently formed hybrid population of threespine stickleback. Mol Ecol (2012) 1.56
A hybrid design for studying genetic influences on risk of diseases with onset early in life. Am J Hum Genet (2005) 1.56
Successful design and conduct of genome-wide association studies. Hum Mol Genet (2007) 1.55
Haplotype structure and phenotypic associations in the chromosomal regions surrounding two Arabidopsis thaliana flowering time loci. Genetics (2004) 1.55
Molecular genetic studies of gene identification for osteoporosis: a 2004 update. J Bone Miner Res (2006) 1.52
Chronic obstructive pulmonary disease in alpha1-antitrypsin PI MZ heterozygotes: a meta-analysis. Thorax (2004) 1.48
Genetic risk factors for portopulmonary hypertension in patients with advanced liver disease. Am J Respir Crit Care Med (2009) 1.44
Maximizing the information content of experiments in systems biology. PLoS Comput Biol (2013) 1.43
Association mapping of North American spring wheat breeding germplasm reveals loci conferring resistance to Ug99 and other African stem rust races. BMC Plant Biol (2015) 1.43
Promoter variation in the DC-SIGN-encoding gene CD209 is associated with tuberculosis. PLoS Med (2006) 1.42
The OPRD1 and OPRK1 loci in alcohol or drug dependence: OPRD1 variation modulates substance dependence risk. Mol Psychiatry (2007) 1.41
Association studies for asthma and atopic diseases: a comprehensive review of the literature. Respir Res (2003) 1.39
Genome-wide association studies in cancer--current and future directions. Carcinogenesis (2009) 1.39
Genetic insights into schizophrenia. Can J Psychiatry (2001) 1.38
Impact of human population history on distributions of individual-level genetic distance. Hum Genomics (2005) 1.38
Identification of a genetic cluster influencing memory performance and hippocampal activity in humans. Proc Natl Acad Sci U S A (2006) 1.38
Interaction of NK inhibitory receptor genes with HLA-C and MHC class II alleles in Hepatitis C virus infection outcome. Mol Immunol (2008) 1.36
Validation of a small set of ancestral informative markers for control of population admixture in African Americans. Am J Epidemiol (2011) 1.36
Single nucleotide polymorphism seeking long term association with complex disease. Nucleic Acids Res (2002) 1.33
Candidate gene association studies and risk of childhood acute lymphoblastic leukemia: a systematic review and meta-analysis. Haematologica (2010) 1.33
Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. Biol Psychiatry (2013) 1.32
Association of the 5'-upstream regulatory region of the alpha7 nicotinic acetylcholine receptor subunit gene (CHRNA7) with schizophrenia. Schizophr Res (2009) 1.32
The future of genetic studies of complex human diseases. Science (1996) 64.76
Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet (1993) 51.42
Genetic dissection of complex traits. Science (1994) 29.54
Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. Science (1998) 18.23
Origins and affinities of modern humans: a comparison of mitochondrial and nuclear genetic data. Am J Hum Genet (1995) 17.65
A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. Am J Hum Genet (1998) 15.76
Haplotype relative risks: an easy reliable way to construct a proper control sample for risk calculations. Ann Hum Genet (1987) 13.98
Inbreeding coefficients and coalescence times. Genet Res (1991) 10.66
Genetic absolute dating based on microsatellites and the origin of modern humans. Proc Natl Acad Sci U S A (1995) 9.25
Drift, admixture, and selection in human evolution: a study with DNA polymorphisms. Proc Natl Acad Sci U S A (1991) 8.14
Genetic association mapping based on discordant sib pairs: the discordant-alleles test. Am J Hum Genet (1998) 7.02
Ethnic-affiliation estimation by use of population-specific DNA markers. Am J Hum Genet (1997) 6.72
HLA and insulin gene associations with IDDM. Genet Epidemiol (1989) 6.53
Mapping genes underlying ethnic differences in disease risk by linkage disequilibrium in recently admixed populations. Am J Hum Genet (1997) 6.35
A conditional inference framework for extending the transmission/disequilibrium test. Hum Hered (1998) 5.70
Microsatellite diversity and the demographic history of modern humans. Proc Natl Acad Sci U S A (1997) 4.96
Association mapping in structured populations. Am J Hum Genet (2000) 16.79
A private allele ubiquitous in the Americas. Biol Lett (2007) 1.69
Using population mixtures to optimize the utility of genomic databases: linkage disequilibrium and association study design in India. Ann Hum Genet (2007) 1.65
Microsatellite evolution in modern humans: a comparison of two data sets from the same populations. Ann Hum Genet (2000) 1.14
Optimal estimation of transposition rates of insertion sequences for molecular epidemiology. Stat Med (2001) 1.13