Polyriboinosinic polyribocytidylic acid (poly(I:C)) induces stable maturation of functionally active human dendritic cells.

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Published in J Immunol on July 01, 1999

Authors

R M Verdijk1, T Mutis, B Esendam, J Kamp, C J Melief, A Brand, E Goulmy

Author Affiliations

1: Department of Immunohematology and Blood Bank, Leiden University Medical Center, Leiden, The Netherlands. verdijk@rullf2.medfac.leidenuniv.nl

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The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes. J Immunol (1994) 4.37

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Pretransplantation blood transfusion revisited. N Engl J Med (1991) 3.72

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Randomised controlled trial comparing transfusion of leucocyte-depleted or buffy-coat-depleted blood in surgery for colorectal cancer. Lancet (1994) 3.45

Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro. Cell (1990) 3.44

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High-dose intravenous immunoglobulin treatment in chronic inflammatory demyelinating polyneuropathy: a double-blind, placebo-controlled, crossover study. Neurology (1990) 3.05

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CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy. Nat Med (1999) 2.77

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Peptide selection by MHC class I molecules. Nature (1991) 2.01

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Cooperation between cytotoxic and helper T lymphocytes in protection against lethal Sendai virus infection. Protection by T cells is MHC-restricted and MHC-regulated; a model for MHC-disease associations. J Exp Med (1986) 1.97

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The HLA-A*0201-restricted H-Y antigen contains a posttranslationally modified cysteine that significantly affects T cell recognition. Immunity (1997) 1.78

Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation. Nature (1992) 1.76

Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein. J Exp Med (1999) 1.76

Transfusion of red cells is associated with increased incidence of bacterial infection after colorectal surgery: a prospective study. Transfusion (1997) 1.75

[Quack diagnostic methods]. Dtsch Med Wochenschr (1983) 1.73

Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction. Proc Natl Acad Sci U S A (1996) 1.72

T90/44 (9.3 antigen). A cell surface molecule with a function in human T cell activation. Eur J Immunol (1986) 1.62

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Triggers and appropriateness of red blood cell transfusions in the postpartum patient--a retrospective audit. Vox Sang (2009) 1.60

Management practices associated with the incidence rate of clinical mastitis. J Dairy Sci (1999) 1.60

Antigen capture and major histocompatibility class II compartments of freshly isolated and cultured human blood dendritic cells. J Exp Med (1995) 1.60

Measures to prevent TRALI. Vox Sang (2007) 1.58

Interaction of immunoglobulins with liposomes. J Clin Invest (1974) 1.58

Occurrence of allogeneic HLA and non-HLA antibodies after transfusion of prestorage filtered platelets and red blood cells: a prospective study. Blood (1995) 1.58

The effect of fresh versus stored blood on post-operative bleeding after coronary bypass surgery: a prospective randomized study. Br J Haematol (1989) 1.56

Pregnancy and severe aplastic anaemia: causal relation or coincidence? . Br J Haematol (1998) 1.56

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[Need for blood transfusion in premature infants in 2 Dutch perinatology centres particularly determined by blood sampling for diagnosis]. Ned Tijdschr Geneeskd (2008) 1.52

Abrogation of CTL epitope processing by single amino acid substitution flanking the C-terminal proteasome cleavage site. J Immunol (2000) 1.52

Peptide loading of empty major histocompatibility complex molecules on RMA-S cells allows the induction of primary cytotoxic T lymphocyte responses. Eur J Immunol (1991) 1.51

Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis. J Exp Med (2001) 1.50

Specific killing of cytotoxic T cells and antigen-presenting cells by CD4+ cytotoxic T cell clones. A novel potentially immunoregulatory T-T cell interaction in man. J Exp Med (1990) 1.48

Both Fc receptors and lymphocyte-function-associated antigen 1 on human T gamma lymphocytes are required for antibody-dependent cellular cytotoxicity (killer cell activity). Eur J Immunol (1984) 1.48

Leucocyte depletion of perioperative blood transfusion does not affect long-term survival and recurrence in patients with gastrointestinal cancer. Br J Surg (2009) 1.48

Tetrameric HLA class I-minor histocompatibility antigen peptide complexes demonstrate minor histocompatibility antigen-specific cytotoxic T lymphocytes in patients with graft-versus-host disease. Nat Med (1999) 1.47

Characterization of HLA-B57-restricted human immunodeficiency virus type 1 Gag- and RT-specific cytotoxic T lymphocyte responses. J Gen Virol (1998) 1.47

Beneficial effects of leukocyte depletion of transfused blood on postoperative complications in patients undergoing cardiac surgery: a randomized clinical trial. Circulation (1998) 1.47

Evidence for a protective role of interferon in resistance to murine cytomegalovirus and its control by non-H-2-linked genes. Infect Immun (1982) 1.44

Vaccination with HPV16 peptides of patients with advanced cervical carcinoma: clinical evaluation of a phase I-II trial. Eur J Cancer (1999) 1.44

Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences. J Immunol (1995) 1.44

Involvement of inhibitory NKRs in the survival of a subset of memory-phenotype CD8+ T cells. Nat Immunol (2001) 1.44

Failure or success in the restoration of virus-specific cytotoxic T lymphocyte response defects by dendritic cells. J Immunol (1988) 1.43

Cord blood banking. Vox Sang (2008) 1.41

Episialin (MUC1) inhibits cytotoxic lymphocyte-target cell interaction. J Immunol (1993) 1.40

Induction of CD11a/leukocyte function antigen-1 and CD54/intercellular adhesion molecule-1 on hairy cell leukemia cells is accompanied by enhanced susceptibility to T-cell but not lymphokine-activated killer-cell cytotoxicity. Blood (1992) 1.40

Tumor eradication by wild-type p53-specific cytotoxic T lymphocytes. J Exp Med (1997) 1.40

Adenoviruses activate human dendritic cells without polarization toward a T-helper type 1-inducing subset. J Virol (1999) 1.40

Alterations in cord blood leukocyte subsets of patients with severe hemolytic disease after intrauterine transfusion therapy. J Pediatr (1997) 1.39

Progressive systemic sclerosis sine scleroderma in a child presenting as nocturnal seizures and Raynaud's phenomenon. Acta Paediatr (1993) 1.39

[Blood group immunization: results of treatment of fetal anemia with intra-uterine intravascular blood transfusion in the Netherlands, 1987-1995]. Ned Tijdschr Geneeskd (1999) 1.39

Bone marrow transplantation or chemotherapy as post-remission treatment of adult acute myelogenous leukemia. Ann Hematol (1991) 1.39

Universal leucocyte-depletion of blood components: cell concentrates and plasma. Vox Sang (2001) 1.39

UTY gene codes for an HLA-B60-restricted human male-specific minor histocompatibility antigen involved in stem cell graft rejection: characterization of the critical polymorphic amino acid residues for T-cell recognition. Blood (2000) 1.38

HLA class I-eluted platelets as an alternative to HLA-matched platelets. Transfusion (1996) 1.38

Cutting edge: the HLA-A*0101-restricted HY minor histocompatibility antigen originates from DFFRY and contains a cysteinylated cysteine residue as identified by a novel mass spectrometric technique. J Immunol (1999) 1.38

Splenocyte plaque assay for the detection of murine leukemia virus. Proc Soc Exp Biol Med (1975) 1.37

Generating lineage-specific markers to study Drosophila development. Dev Genet (1991) 1.37

Incidence of clinical mastitis in dairy herds grouped in three categories by bulk milk somatic cell counts. J Dairy Sci (1998) 1.37

MHC class I antigen processing of an adenovirus CTL epitope is linked to the levels of immunoproteasomes in infected cells. J Immunol (2000) 1.37

[Application of leukocyte-poor blood products. Work Group Blood Group Serology from the Medical Advisory Commission of the College for Blood Transfusion]. Ned Tijdschr Geneeskd (1995) 1.37

A minor transplantation antigen detected by MHC-restricted cytotoxic T lymphocytes during graft-versus-host disease. Nature (1983) 1.34

N-linked glycan modification on antigen-presenting cells restores an allospecific cytotoxic T cell response. J Exp Med (1990) 1.34

Reduced cell surface expression of HLA-C molecules correlates with restricted peptide binding and stable TAP interaction. J Immunol (1998) 1.34

Highly efficient transduction of human monocyte-derived dendritic cells with subgroup B fiber-modified adenovirus vectors enhances transgene-encoded antigen presentation to cytotoxic T cells. J Immunol (2001) 1.34

Adhesion of T and B lymphocytes to extracellular matrix and endothelial cells can be regulated through the beta subunit of VLA. J Cell Biol (1992) 1.33

A randomized comparison of transfusion triggers in elective orthopaedic surgery using leucocyte-depleted red blood cells. Vox Sang (2009) 1.31

Mechanisms of induction of primary virus-specific cytotoxic T lymphocyte responses. Eur J Immunol (1992) 1.30