Published in Antimicrob Agents Chemother on July 01, 1999
Phenotypic characterization of pncA mutants of Mycobacterium tuberculosis. Antimicrob Agents Chemother (2000) 2.15
pncA mutations as a major mechanism of pyrazinamide resistance in Mycobacterium tuberculosis: spread of a monoresistant strain in Quebec, Canada. Antimicrob Agents Chemother (2000) 2.10
Pyrazinamide susceptibility testing in Mycobacterium tuberculosis: a systematic review with meta-analyses. Antimicrob Agents Chemother (2011) 1.62
Comparison of phenotypic and genotypic methods for pyrazinamide susceptibility testing with Mycobacterium tuberculosis. J Clin Microbiol (2000) 1.51
Pyrazinamide resistance and pncA gene mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother (2008) 1.37
Effect of pyrazinamidase activity on pyrazinamide resistance in Mycobacterium tuberculosis. Tuberculosis (Edinb) (2009) 1.29
pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis isolates in Portugal. Antimicrob Agents Chemother (2004) 1.17
Systematic analysis of pyrazinamide-resistant spontaneous mutants and clinical isolates of Mycobacterium tuberculosis. Antimicrob Agents Chemother (2012) 1.13
Study of the structure-activity relationships for the pyrazinamidase (PncA) from Mycobacterium tuberculosis. Biochem J (2001) 1.10
pncA mutations in clinical Mycobacterium tuberculosis isolates from Korea. BMC Infect Dis (2001) 1.06
A Global Perspective on Pyrazinamide Resistance: Systematic Review and Meta-Analysis. PLoS One (2015) 0.99
Role of pncA and rpsA gene sequencing in detection of pyrazinamide resistance in Mycobacterium tuberculosis isolates from southern China. J Clin Microbiol (2013) 0.98
Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis in Brazil. Antimicrob Agents Chemother (2005) 0.96
Detection by denaturing gradient gel electrophoresis of pncA mutations associated with pyrazinamide resistance in Mycobacterium tuberculosis isolates from the United States-Mexico border region. Antimicrob Agents Chemother (2005) 0.94
Systematic review of mutations in pyrazinamidase associated with pyrazinamide resistance in Mycobacterium tuberculosis clinical isolates. Antimicrob Agents Chemother (2015) 0.94
Peruvian and globally reported amino acid substitutions on the Mycobacterium tuberculosis pyrazinamidase suggest a conserved pattern of mutations associated to pyrazinamide resistance. Infect Genet Evol (2009) 0.93
Spectrum of pncA mutations in multidrug-resistant Mycobacterium tuberculosis isolates obtained in Latvia. Antimicrob Agents Chemother (2004) 0.86
Mycobacterium smegmatis has two pyrazinamidase enzymes, PncA and pzaA. J Bacteriol (2000) 0.85
Mechanisms of Pyrazinamide Action and Resistance. Microbiol Spectr (2013) 0.83
Association between pncA gene mutations, pyrazinamidase activity, and pyrazinamide susceptibility testing in Mycobacterium tuberculosis. Antimicrob Agents Chemother (2014) 0.80
Rapid detection of Mycobacterium tuberculosis and pyrazinamide susceptibility related to pncA mutations in sputum specimens through an integrated gene-to-protein function approach. J Clin Microbiol (2013) 0.79
Multicenter evaluation of a nonweekend reading schedule for radiometric pyrazinamide susceptibility testing of Mycobacterium tuberculosis. J Clin Microbiol (2002) 0.77
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature (1998) 60.62
Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology. J Clin Microbiol (1993) 45.22
Mutations in pncA, a gene encoding pyrazinamidase/nicotinamidase, cause resistance to the antituberculous drug pyrazinamide in tubercle bacillus. Nat Med (1996) 8.94
Simple pyrazinamidase and urease tests for routine identification of mycobacteria. Am Rev Respir Dis (1974) 7.40
Activation of pyrazinamide and nicotinamide in acidic environments in vitro. Am Rev Tuberc (1954) 5.58
Pyrazinamide susceptibility and amidase activity of tubercle bacilli. Am Rev Respir Dis (1967) 5.45
Simultaneous genotyping and species identification using hybridization pattern recognition analysis of generic Mycobacterium DNA arrays. Genome Res (1998) 3.85
Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis. Antimicrob Agents Chemother (1997) 3.75
A Ser315Thr substitution in KatG is predominant in genetically heterogeneous multidrug-resistant Mycobacterium tuberculosis isolates originating from the St. Petersburg area in Russia. Antimicrob Agents Chemother (1998) 3.70
Mutations associated with pyrazinamide resistance in pncA of Mycobacterium tuberculosis complex organisms. Antimicrob Agents Chemother (1997) 3.46
Pyrazinamide sterilizing activity in vitro against semidormant Mycobacterium tuberculosis bacterial populations. Am Rev Respir Dis (1992) 2.34
Mutation in pncA is a major mechanism of pyrazinamide resistance in Mycobacterium tuberculosis. Tuber Lung Dis (1997) 2.34
Drug-resistant tuberculosis: inconsistent results of pyrazinamide susceptibility testing. JAMA (1995) 1.83
Activity of n-propyl pyrazinoate against pyrazinamide-resistant Mycobacterium tuberculosis: investigations into mechanism of action of and mechanism of resistance to pyrazinamide. Antimicrob Agents Chemother (1995) 1.38
A Ser315Thr substitution in KatG is predominant in genetically heterogeneous multidrug-resistant Mycobacterium tuberculosis isolates originating from the St. Petersburg area in Russia. Antimicrob Agents Chemother (1998) 3.70
Detection and identification of mycobacteria by amplification of a segment of the gene coding for the 32-kilodalton protein. J Clin Microbiol (1992) 3.62
Solid-phase radioimmunoassay of rubella virus immunoglobulin G and immunoglobulin M antibodies. J Clin Microbiol (1976) 2.94
Comparison of polymerase chain reaction with culture and enzyme immunoassay for diagnosis of pertussis. J Clin Microbiol (1993) 2.41
Identification of mycobacteria by PCR-based sequence determination of the 32-kilodalton protein gene. J Clin Microbiol (1994) 2.20
Solid-phase radioimmunoassay of rubella virus immunoglobulin M antibodies: comparison with sucrose density gradient centrifugation test. J Clin Microbiol (1977) 1.96
katG mutations in isoniazid-resistant Mycobacterium tuberculosis isolates recovered from Finnish patients. Antimicrob Agents Chemother (1996) 1.82
Whooping cough caused by Bordetella pertussis and Bordetella parapertussis in an immunized population. JAMA (1998) 1.57
Serological diagnosis of pertussis: IgM, IgA and IgG antibodies against Bordetella pertussis measured by enzyme-linked immunosorbent assay (ELISA). Scand J Infect Dis (1982) 1.56
Enzyme-linked immunosorbent assay (ELISA) with bacterial sonicate antigen for IgM, IgA, and IgG antibodies to Francisella tularensis: comparison with bacterial agglutination test and ELISA with lipopolysaccharide antigen. J Infect Dis (1983) 1.50
Intracranial aneurysms in three patients with disseminated Lyme borreliosis: cause or chance association? J Neurol Neurosurg Psychiatry (1998) 1.44
Effect of sport stress on lymphocyte transformation and antibody formation. Clin Exp Immunol (1978) 1.43
[Genetic marking of polyresistant mycobacterium tuberculosis strains isolated in the north-west of Russia]. Probl Tuberk (1999) 1.40
Acute otitis media and respiratory virus infections. Pediatr Infect Dis J (1989) 1.40
Solid-phase radioimmunoassay of human immunoglobulin M and immunoglobulin G antibodies against herpes simplex virus type 1 capsid, envelope, and excreted antigens. Infect Immun (1977) 1.40
Intrafamilial spread of pertussis. J Pediatr (1983) 1.39
[The tactics of management of patients with mycobacteriosis of the lungs]. Probl Tuberk (1991) 1.38
Prevalence of Borrelia burgdorferi in Ixodes ricinus ticks in urban recreational areas of Helsinki. J Clin Microbiol (1999) 1.36
Radioimmunoassay of class-specific antibodies (RIACA): chicken antibodies to bovine serum albumin. Immunochemistry (1975) 1.33
Impact of polymerase chain reaction on clinical pertussis research: Finnish and Swiss experiences. J Infect Dis (1996) 1.31
Measurement of immunoglobulin M, immunoglobulin G, and immunoglobulin A antibodies against Yersinia enterocolitica by enzyme-linked immunosorbent assay: comparison of lipopolysaccharide and whole bacterium as antigen. J Clin Microbiol (1981) 1.31
Diversity of the 32-kilodalton protein gene may form a basis for species determination of potentially pathogenic mycobacterial species. J Clin Microbiol (1997) 1.30
Outcomes of Bordetella pertussis infection in different age groups of an immunized population. J Infect Dis (1994) 1.29
Survey of drug-resistant tuberculosis in northwestern Russia from 1984 through 1994. Eur J Clin Microbiol Infect Dis (1998) 1.28
Prospective evaluation of the GenoType assay for routine identification of mycobacteria. Eur J Clin Microbiol Infect Dis (2004) 1.25
Line probe assay in the rapid detection of rifampin-resistant Mycobacterium tuberculosis directly from clinical specimens. Scand J Infect Dis (1999) 1.25
Decreased interleukin-4 and increased gamma interferon production by peripheral blood mononuclear cells of patients with Lyme borreliosis. Infect Immun (1996) 1.20
Morphine concentrations in plasma after intramuscular administration. Br J Anaesth (1975) 1.20
Sensitive and specific polymerase chain reaction assays for detection of Bordetella pertussis in nasopharyngeal specimens. J Pediatr (1994) 1.19
Borrelia burgdorferi detected by culture and PCR in clinical relapse of disseminated Lyme borreliosis. Ann Med (1999) 1.18
Primers are decisive for sensitivity of PCR. Biotechniques (1994) 1.17
Prospective evaluation of pyrosequencing for the rapid detection of isoniazid and rifampin resistance in clinical Mycobacterium tuberculosis isolates. Eur J Clin Microbiol Infect Dis (2008) 1.17
C reactive protein in the evaluation of febrile illness. Arch Dis Child (1986) 1.16
The expanding clinical spectrum of ocular lyme borreliosis. Ophthalmology (2000) 1.15
Solid-phase radioimmunoassay of herpes simplex virus IgG and IgM antibodies. J Immunol Methods (1977) 1.13
Diagnosis of pertussis. J Infect (1984) 1.13
Cell-mediated immune responses to antigens of Bordetella pertussis and protection against pertussis in school children. Pediatr Infect Dis J (1999) 1.12
Inflammatory brain changes in Lyme borreliosis. A report on three patients and review of literature. Brain (1996) 1.10
Rapid identification of Bordetella pertussis pertactin gene variants using LightCycler real-time polymerase chain reaction combined with melting curve analysis and gel electrophoresis. Emerg Infect Dis (2001) 1.09
Rapid detection of rifampin-resistant Mycobacterium tuberculosis by sequencing and line probe assay. Scand J Infect Dis (1998) 1.07
Genetic diversity among Mycobacterium avium complex AccuProbe-positive isolates. J Clin Microbiol (1996) 1.05
Serologic diagnosis of pertussis: evaluation of pertussis toxin and other antigens in enzyme-linked immunosorbent assay. J Infect Dis (1990) 1.05
Effect of prophylactic acetaminophen administration on reaction to DTP vaccination. Acta Paediatr Scand (1988) 1.03
Rapid differentiation of Borrelia garinii from Borrelia afzelii and Borrelia burgdorferi sensu stricto by LightCycler fluorescence melting curve analysis of a PCR product of the recA gene. J Clin Microbiol (2000) 1.03
Immunosuppression by halothane. Br Med J (1973) 1.02
Serologic diagnosis of pertussis: comparison of enzyme-linked immunosorbent assay and bacterial agglutination. J Infect Dis (1983) 1.01
Clinical role of respiratory virus infection in acute otitis media. Pediatrics (1990) 1.00
Antibodies to filamentous hemagglutinin of Bordetella pertussis and protection against whooping cough in schoolchildren. J Infect Dis (1994) 1.00
Evaluation of a novel strip test, GenoType Mycobacterium CM/AS, for species identification of mycobacterial cultures. Clin Microbiol Infect (2006) 1.00
Effects of thermocyclers and primers on the reproducibility of banding patterns in randomly amplified polymorphic DNA analysis. Mol Cell Probes (1994) 1.00
Antibodies against whole sonicated Borrelia burgdorferi spirochetes, 41-kilodalton flagellin, and P39 protein in patients with PCR- or culture-proven late Lyme borreliosis. J Clin Microbiol (1995) 0.98
Fatal encephalitis caused by concomitant infection with tick-borne encephalitis virus and Borrelia burgdorferi. Clin Infect Dis (1993) 0.97
DTP and DTP-inactivated polio vaccines: comparison of adverse reactions and IGG, IGM and IGA antibody responses to DTP. Acta Paediatr Scand (1980) 0.96
Antigen attachment in ELISA. J Immunol Methods (1980) 0.96
Monoclonal antibodies reacting selectively with core and O-polysaccharide of Yersinia enterocolitica O:3 lipopolysaccharide. Acta Pathol Microbiol Immunol Scand C (1987) 0.94
Outcomes of Bordetella infections in vaccinated children: effects of bacterial number in the nasopharynx and patient age. Clin Diagn Lab Immunol (1999) 0.93
Immunity to tetanus in Finland. Scand J Infect Dis (1980) 0.93
Enzyme-linked immunosorbent assay (ELISA) for antibodies to purified protein derivative of tuberculin (PPD). IgM-, IgA- and IgG- anti-PPD antibodies in active pulmonary tuberculosis. Eur J Respir Dis (1982) 0.92
A binding function for curve-fitting in enzyme-linked immunosorbent assay (ELISA) and its use in estimating the amounts of total and high affinity antibodies. Int J Biomed Comput (1982) 0.92
Evaluation of pooled and individual components of Bordetella pertussis as antigens in an enzyme immunoassay for diagnosis of pertussis. Eur J Clin Microbiol Infect Dis (1993) 0.92
Interaction between Borrelia burgdorferi and immature human dendritic cells. Scand J Immunol (2003) 0.91
Acellular vaccines containing reduced quantities of pertussis antigens as a booster in adolescents. Pediatrics (1999) 0.90
Current status of pertussis and pertussis vaccination in Finland. Ann Clin Res (1982) 0.90
Tube phagocytosis, a novel way for neutrophils to Phagocytize borrelia burgdorferi. Infect Immun (1998) 0.89
Measurement of IgM and IgG antibodies to Yersinia by solid-phase radioimmunoassay. J Infect Dis (1978) 0.89
Borrelia burgdorferi--induced oxidative burst, calcium mobilization, and phagocytosis of human neutrophils are complement dependent. J Infect Dis (2000) 0.88
Monoclonal antibodies to Bacteroides fragilis lipopolysaccharide. J Clin Microbiol (1984) 0.88
Specific antibody deficiency in children with recurrent respiratory infections: a controlled study with follow-up. Clin Exp Immunol (2013) 0.87
Alkaline phosphatase in the developing bursa of Fabricius. A comparative study of the cyclophosphamide- and testosterone-induced immunodeficiencies in the chick embryo. Scand J Immunol (1977) 0.87
Subacute multiple-site osteomyelitis caused by Borrelia burgdorferi. Clin Infect Dis (1994) 0.87
Comparison of amplicor and 32-kilodalton PCR for detection of Mycobacterium tuberculosis from sputum specimens. J Clin Microbiol (1996) 0.87
Extremely high prevalence of multidrug resistant tuberculosis in Murmansk, Russia: a population-based study. Eur J Clin Microbiol Infect Dis (2011) 0.86
Antibody and cell-mediated immune responses to booster immunization with a new acellular pertussis vaccine in school children. Vaccine (1998) 0.86
Ligase chain reaction assay is clinically useful in the discrimination of smear-positive pulmonary tuberculosis from atypical mycobacterioses. Ann Med (2000) 0.85