Published in EMBO J on May 04, 1999
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Yap tunes airway epithelial size and architecture by regulating the identity, maintenance, and self-renewal of stem cells. Dev Cell (2014) 1.42
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Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth. Nat Cell Biol (2015) 1.39
YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14. Oncogene (2012) 1.36
YAP oncogene overexpression supercharges colon cancer proliferation. Cell Cycle (2012) 1.34
Emerging roles of TEAD transcription factors and its coactivators in cancers. Cancer Biol Ther (2013) 1.34
Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis. Am J Physiol Lung Cell Mol Physiol (2014) 1.29
The Hippo-YAP signaling pathway and contact inhibition of growth. J Cell Sci (2014) 1.29
PTPN14 is required for the density-dependent control of YAP1. Genes Dev (2012) 1.23
Novel TFAP2B mutations that cause Char syndrome provide a genotype-phenotype correlation. Am J Hum Genet (2001) 1.20
PTPN14 interacts with and negatively regulates the oncogenic function of YAP. Oncogene (2012) 1.17
The corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1. Mol Cell Biol (2004) 1.16
Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression. Cancer Res (2010) 1.16
Cell cycle and developmental control of hematopoiesis by Runx1. J Cell Physiol (2009) 1.16
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Yes-associated protein regulates the hepatic response after bile duct ligation. Hepatology (2012) 1.15
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The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase. Br J Cancer (2003) 1.14
Yap1 is required for endothelial to mesenchymal transition of the atrioventricular cushion. J Biol Chem (2014) 1.13
JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis. Cell Death Dis (2010) 1.13
Yes-associated protein 1 is widely expressed in human brain tumors and promotes glioblastoma growth. J Neuropathol Exp Neurol (2011) 1.10
Wbp2 cooperates with Yorkie to drive tissue growth downstream of the Salvador-Warts-Hippo pathway. Cell Death Differ (2011) 1.06
Identification of TAZ as a binding partner of the polyomavirus T antigens. J Virol (2004) 1.05
Yes-associated protein 65 (YAP) expands neural progenitors and regulates Pax3 expression in the neural plate border zone. PLoS One (2011) 1.05
Runx2 induces acute myeloid leukemia in cooperation with Cbfbeta-SMMHC in mice. Blood (2009) 1.03
A novel acetylation cycle of transcription co-activator Yes-associated protein that is downstream of Hippo pathway is triggered in response to SN2 alkylating agents. J Biol Chem (2012) 1.02
Identification, basic characterization and evolutionary analysis of differentially spliced mRNA isoforms of human YAP1 gene. Gene (2012) 1.02
PP1A-mediated dephosphorylation positively regulates YAP2 activity. PLoS One (2011) 1.01
PEBP2-beta/CBF-beta-dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis. Blood (2008) 1.00
Loss of Yes-associated protein (YAP) expression is associated with estrogen and progesterone receptors negativity in invasive breast carcinomas. Breast Cancer Res Treat (2011) 1.00
Filamin A-bound PEBP2beta/CBFbeta is retained in the cytoplasm and prevented from functioning as a partner of the Runx1 transcription factor. Mol Cell Biol (2005) 0.96
Nedd4 mediates ErbB4 JM-a/CYT-1 ICD ubiquitination and degradation in MDCK II cells. FASEB J (2009) 0.96
Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73. J Cell Biol (2006) 0.95
Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer. J Hepatol (2015) 0.95
Biophysical basis of the binding of WWOX tumor suppressor to WBP1 and WBP2 adaptors. J Mol Biol (2012) 0.93
YAP and TAZ regulate skin wound healing. J Invest Dermatol (2013) 0.93
Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation. Hum Mol Genet (2009) 0.93
Control of tissue growth and cell transformation by the Salvador/Warts/Hippo pathway. PLoS One (2012) 0.92
An ENU-induced mutation in AP-2alpha leads to middle ear and ocular defects in Doarad mice. Mamm Genome (2004) 0.92
Integration of mechanical and chemical signals by YAP and TAZ transcription coactivators. Cell Biosci (2013) 0.91
Normal hematopoietic stem cell function in mice with enforced expression of the Hippo signaling effector YAP1. PLoS One (2012) 0.91
What do mechanotransduction, Hippo, Wnt, and TGFβ have in common? YAP and TAZ as key orchestrating molecules in ocular health and disease. Exp Eye Res (2013) 0.90
Nuclear signaling from cadherin adhesion complexes. Curr Top Dev Biol (2015) 0.90
Non-destructive inhibition of metallofullerenol Gd@C(82)(OH)(22) on WW domain: implication on signal transduction pathway. Sci Rep (2012) 0.89
Suppression of beta-amyloid precursor protein signaling into the nucleus by estrogens mediated through complex formation between the estrogen receptor and Fe65. Mol Cell Biol (2006) 0.89
G Protein-Coupled Receptor and RhoA-Stimulated Transcriptional Responses: Links to Inflammation, Differentiation, and Cell Proliferation. Mol Pharmacol (2015) 0.89
YAP1 acts as oncogenic target of 11q22 amplification in multiple cancer subtypes. Oncotarget (2014) 0.89
Structural and functional insights into the TEAD-YAP complex in the Hippo signaling pathway. Protein Cell (2011) 0.89
A Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue Sarcomas. Front Oncol (2015) 0.88
The orphan nuclear receptor estrogen receptor-related receptor gamma negatively regulates BMP2-induced osteoblast differentiation and bone formation. J Biol Chem (2009) 0.88
Shear stress induced by an interstitial level of slow flow increases the osteogenic differentiation of mesenchymal stem cells through TAZ activation. PLoS One (2014) 0.88
YAP regulates the expression of Hoxa1 and Hoxc13 in mouse and human oral and skin epithelial tissues. Mol Cell Biol (2015) 0.87
Biophysical analysis of binding of WW domains of the YAP2 transcriptional regulator to PPXY motifs within WBP1 and WBP2 adaptors. Biochemistry (2011) 0.86
The orphan nuclear receptor SHP is a positive regulator of osteoblastic bone formation. J Bone Miner Res (2010) 0.86
Proline-rich Gla protein 2 is a cell-surface vitamin K-dependent protein that binds to the transcriptional coactivator Yes-associated protein. Proc Natl Acad Sci U S A (2007) 0.86
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Deletion of Irs2 causes reduced kidney size in mice: role for inhibition of GSK3beta? BMC Dev Biol (2010) 0.84
Identification of functional TFAP2A and SP1 binding sites in new TFAP2A-modulated genes. BMC Genomics (2010) 0.84
Loss of RASSF1A synergizes with deregulated RUNX2 signaling in tumorigenesis. Cancer Res (2012) 0.84
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Novel cis-regulatory modules control expression of the Hairy and Enhancer of Split-1 (HES1) transcription factor in myoblasts. J Biol Chem (2011) 0.82
Osteoblast-targeted overexpression of TAZ increases bone mass in vivo. PLoS One (2013) 0.82
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