Published in J Biol Chem on July 16, 1999
The PI3K-PDK1 connection: more than just a road to PKB. Biochem J (2000) 7.00
Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins. J Cell Biol (2001) 2.99
Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells. Genes Dev (2000) 2.62
Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8. Biochem J (2000) 2.58
Rapid caspase-3 activation during apoptosis revealed using fluorescence-resonance energy transfer. EMBO Rep (2000) 2.12
Effect of alpha1-adrenoceptor antagonist exposure on prostate cancer incidence: an observational cohort study. J Urol (2007) 1.77
TNF-induced signaling in apoptosis. J Clin Immunol (1999) 1.71
A house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death. Biochim Biophys Acta (2006) 1.65
Nuclear import of PKCdelta is required for apoptosis: identification of a novel nuclear import sequence. EMBO J (2002) 1.62
The role of mitochondria in osteoarthritis. Nat Rev Rheumatol (2011) 1.59
Neuronal cell death in neonatal hypoxia-ischemia. Ann Neurol (2011) 1.47
Cellular FLICE-like inhibitory protein (C-FLIP): a novel target for cancer therapy. Curr Cancer Drug Targets (2008) 1.40
Caspase-resistant BAP31 inhibits fas-mediated apoptotic membrane fragmentation and release of cytochrome c from mitochondria. Mol Cell Biol (2000) 1.39
Phytaspase, a relocalisable cell death promoting plant protease with caspase specificity. EMBO J (2010) 1.33
Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak. Mol Cancer Ther (2007) 1.29
PERSISTENT TAPETAL CELL1 encodes a PHD-finger protein that is required for tapetal cell death and pollen development in rice. Plant Physiol (2011) 1.28
E1B 19K blocks Bax oligomerization and tumor necrosis factor alpha-mediated apoptosis. J Virol (2001) 1.25
NF-kappaB is required for apoptosis prevention during herpes simplex virus type 1 infection. J Virol (2003) 1.25
Targeting the Anti-Apoptotic Protein c-FLIP for Cancer Therapy. Cancers (Basel) (2011) 1.25
Biology of mitochondria in neurodegenerative diseases. Prog Mol Biol Transl Sci (2012) 1.22
A plant caspase-like protease activated during the hypersensitive response. Plant Cell (2003) 1.18
Nuclear relocalization of the pre-mRNA splicing factor PSF during apoptosis involves hyperphosphorylation, masking of antigenic epitopes, and changes in protein interactions. Mol Biol Cell (2001) 1.14
Mitochondrial and Cell Death Mechanisms in Neurodegenerative Diseases. Pharmaceuticals (Basel) (2010) 1.13
PR-924, a selective inhibitor of the immunoproteasome subunit LMP-7, blocks multiple myeloma cell growth both in vitro and in vivo. Br J Haematol (2010) 1.11
Leptin attenuates cardiac apoptosis after chronic ischaemic injury. Cardiovasc Res (2009) 1.10
Caspase cleavage of the nonstructural protein NS1 mediates replication of Aleutian mink disease parvovirus. J Virol (2003) 1.10
Interferon gamma inhibits growth of human pancreatic carcinoma cells via caspase-1 dependent induction of apoptosis. Gut (2001) 1.07
The effect of hyperthermia on the induction of cell death in brain, testis, and thymus of the adult and developing rat. Cell Stress Chaperones (2002) 1.06
Grape proanthocyanidins induce apoptosis by loss of mitochondrial membrane potential of human non-small cell lung cancer cells in vitro and in vivo. PLoS One (2011) 1.06
UV-Induced cell death in plants. Int J Mol Sci (2013) 1.04
A high throughput drug screen based on fluorescence resonance energy transfer (FRET) for anticancer activity of compounds from herbal medicine. Br J Pharmacol (2007) 1.03
Vitamins E and D3 attenuate demyelination and potentiate remyelination processes of hippocampal formation of rats following local injection of ethidium bromide. Cell Mol Neurobiol (2009) 1.03
Release of annexin V-binding membrane microparticles from cultured human umbilical vein endothelial cells after treatment with camptothecin. BMC Cell Biol (2002) 1.02
Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease. Neurobiol Dis (2007) 1.01
Induction of cell death in rat small intestine by ischemia reperfusion: differential roles of Fas/Fas ligand and Bcl-2/Bax systems depending upon cell types. Histochem Cell Biol (2005) 1.01
Caspase processing and nuclear export of CTP:phosphocholine cytidylyltransferase alpha during farnesol-induced apoptosis. Mol Cell Biol (2002) 1.00
Differential effects of hyperphosphorylation on splicing factor SRp55. Biochem J (2003) 0.99
Role of caspases in dexamethasone-induced apoptosis and activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase in human eosinophils. Clin Exp Immunol (2000) 0.98
Aspirin induces apoptosis in vitro and inhibits tumor growth of human hepatocellular carcinoma cells in a nude mouse xenograft model. Int J Oncol (2011) 0.97
Sialic acid-binding lectin (leczyme) induces caspase-dependent apoptosis-mediated mitochondrial perturbation in Jurkat cells. Int J Oncol (2013) 0.95
E2F-1 induces melanoma cell apoptosis via PUMA up-regulation and Bax translocation. BMC Cancer (2007) 0.95
Epigallocatechin gallate protects against oxidative stress-induced mitochondria-dependent apoptosis in human lens epithelial cells. Mol Vis (2008) 0.95
Heat shock protein and apoptosis in supraspinatus tendinopathy. Clin Orthop Relat Res (2008) 0.95
Chronic treatment with lisinopril decreases proliferative and apoptotic pathways in autosomal recessive polycystic kidney disease. Pediatr Nephrol (2010) 0.95
Frequent promoter hypermethylation of RASSF1A and CASP8 in neuroblastoma. BMC Cancer (2006) 0.94
Mechanism, Structure, and Inhibition of O-GlcNAc Processing Enzymes. Curr Signal Transduct Ther (2010) 0.94
Fluorescent Proteins as Genetically Encoded FRET Biosensors in Life Sciences. Sensors (Basel) (2015) 0.93
Differential modulation of cellular death and survival pathways by conjugated bile acids. BMC Biochem (2001) 0.93
SRC directly phosphorylates Bif-1 and prevents its interaction with Bax and the initiation of anoikis. J Biol Chem (2008) 0.93
Apoptosis and sphingomyelin hydrolysis. The flip side. J Cell Biol (2000) 0.92
Caspases: evolutionary aspects of their functions in vertebrates. J Fish Biol (2009) 0.92
Calpain activator dibucaine induces platelet apoptosis. Int J Mol Sci (2011) 0.91
P2X(7) nucleotide receptors mediate caspase-8/9/3-dependent apoptosis in rat primary cortical neurons. Purinergic Signal (2005) 0.91
Keloid-derived fibroblasts are refractory to Fas-mediated apoptosis and neutralization of autocrine transforming growth factor-beta1 can abrogate this resistance. Am J Pathol (2000) 0.90
TNF-α-induced cardiomyocyte apoptosis contributes to cardiac dysfunction after coronary microembolization in mini-pigs. J Cell Mol Med (2014) 0.90
Chlamydia trachomatis-infected macrophages induce apoptosis of activated T cells by secretion of tumor necrosis factor-alpha in vitro. Med Microbiol Immunol (2003) 0.90
Membrane disruption and cytotoxicity of hydrophobic N-alkylated imino sugars is independent of the inhibition of protein and lipid glycosylation. Biochem J (2003) 0.89
Open reading frame 2, encoded by the latency-related gene of bovine herpesvirus 1, has antiapoptotic activity in transiently transfected neuroblastoma cells. J Virol (2008) 0.89
Downregulation of urokinase-type plasminogen activator receptor (uPAR) induces caspase-mediated cell death in human glioblastoma cells. Clin Exp Metastasis (2000) 0.89
The role of alpha-blockers in the management of prostate cancer. Expert Opin Pharmacother (2004) 0.88
Nanosensing at the single cell level. Spectrochim Acta Part B At Spectrosc (2008) 0.87
IL-1β and IL-18: inflammatory markers or mediators of hypertension? Br J Pharmacol (2014) 0.86
Transgenic mice neuronally expressing baculoviral p35 are resistant to diverse types of induced apoptosis, including seizure-associated neurodegeneration. Proc Natl Acad Sci U S A (2000) 0.86
Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO. BMC Pharmacol (2007) 0.86
Hydrogen peroxide induces caspase activation and programmed cell death in the amitochondrial Tritrichomonas foetus. Histochem Cell Biol (2003) 0.85
Anisomycin activates JNK and sensitises DU 145 prostate carcinoma cells to Fas mediated apoptosis. Br J Cancer (2002) 0.85
Grape seed proanthocyanidins (GSPs) inhibit the growth of cervical cancer by inducing apoptosis mediated by the mitochondrial pathway. PLoS One (2014) 0.84
Knockdown of GRP78 promotes apoptosis in pancreatic acinar cells and attenuates the severity of cerulein and LPS induced pancreatic inflammation. PLoS One (2014) 0.84
Decreased risk of bladder cancer in men treated with quinazoline-based α1-adrenoceptor antagonists. Gene Ther Mol Biol (2008) 0.83
Ocimum gratissimum Aqueous Extract Induces Apoptotic Signalling in Lung Adenocarcinoma Cell A549. Evid Based Complement Alternat Med (2010) 0.83
Nocardia asteroides strain GUH-2 induces proteasome inhibition and apoptotic death of cultured cells. Res Microbiol (2006) 0.83
Insig2 is associated with colon tumorigenesis and inhibits Bax-mediated apoptosis. Int J Cancer (2008) 0.82
cDNA cloning and promoter analysis of rat caspase-9. Biochem J (2001) 0.81
Radiation enhances caspase 3 cleavage of Rad51 in BRCA2-defective cells. Radiat Res (2008) 0.81
The pan-inhibitor of Aurora kinases danusertib induces apoptosis and autophagy and suppresses epithelial-to-mesenchymal transition in human breast cancer cells. Drug Des Devel Ther (2015) 0.81
Caspase-resistant VirD2 protein provides enhanced gene delivery and expression in plants. Plant Cell Rep (2007) 0.81
Induction of apoptosis by 3-amino-6-(3-aminopropyl)-5,6-dihydro-5,11-dioxo-11H-indeno[1,2-c]isoquinoline via modulation of MAPKs (p38 and c-Jun N-terminal kinase) and c-Myc in HL-60 human leukemia cells. J Nat Prod (2011) 0.81
The proapoptotic effect of traditional and novel nonsteroidal anti-inflammatory drugs in mammalian and yeast cells. Oxid Med Cell Longev (2013) 0.80
Antiproliferative and cytotoxic effects of resveratrol in mitochondria-mediated apoptosis in rat b103 neuroblastoma cells. Korean J Physiol Pharmacol (2012) 0.80
Exposure to the neurotoxic dinoflagellate, Alexandrium catenella, induces apoptosis of the hemocytes of the oyster, Crassostrea gigas. Mar Drugs (2013) 0.80
Apoptosis of human breast carcinoma cells in the presence of disialosyl gangliosides: II. Treatment of SKBR3 cells with GD3 and GD1b gangliosides. Glycoconj J (2004) 0.80
Oligodeoxynucleotide 5mers containing a 5'-CpG induce apoptosis through a mitochondrial mechanism in T lymphocytic leukaemia cells. Nucleic Acids Res (2000) 0.80
Adaptive cytoprotection induced by pretreatment with ethanol protects against gastric cell damage by NSAIDs. Dig Dis Sci (2004) 0.80
Association of a Methanol Extract of Rheum undulatum L. Mediated Cell Death in AGS Cells with an Intrinsic Apoptotic Pathway. J Pharmacopuncture (2015) 0.80
Interleukin-1beta converting enzyme subfamily inhibitors prevent induction of CD86 molecules by butyrate through a CREB-dependent mechanism in HL60 cells. Immunology (2003) 0.79
Apoptosis induced by genipin in human leukemia K562 cells: involvement of c-Jun N-terminal kinase in G₂/M arrest. Acta Pharmacol Sin (2011) 0.79
A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition. Sci Rep (2016) 0.79
Spatial analysis of cell death and Hsp70 induction in brain, thymus, and bone marrow of the hyperthermic rat. Cell Stress Chaperones (2003) 0.79
Downregulation of GRP78 and XIAP is correlated with apoptosis during cerulein-induced acute pancreatitis in rats via regulation of caspase activation. Mol Med Rep (2012) 0.79
Mitochondrial permeability transition pore: a promising target for the treatment of Parkinson's disease. Protoplasma (2016) 0.78
Kinetics of T lymphocyte apoptosis and the cellular immune response in SIVmac239-infected rhesus macaques. J Med Primatol (2008) 0.78
CpG island methylation of TMS1/ASC and CASP8 genes in cervical cancer. Eur J Med Res (2009) 0.78
A non-toxic fluorogenic dye for mitochondria labeling. Biochim Biophys Acta (2013) 0.78
Antioxidant activity and antiapoptotic effect of Asparagus racemosus root extracts in human lung epithelial H460 cells. Exp Ther Med (2010) 0.78
Cystamine attenuates lupus-associated apoptosis of ventricular tissue by suppressing both intrinsic and extrinsic pathways. J Cell Mol Med (2012) 0.78
Apoptosis of AGS human gastric adenocarcinoma cells by methanolic extract of Dictamnus. Pharmacogn Mag (2015) 0.77
Effects of prostaglandin E2 on gastric irritant-induced apoptosis. Dig Dis Sci (2002) 0.77
Eliminating caspase-7 and cathepsin B cross-reactivity on fluorogenic caspase-3 substrates. Mol Biosyst (2016) 0.77
Altered of apoptotic markers of both extrinsic and intrinsic pathways induced by hepatitis C virus infection in peripheral blood mononuclear cells. Virol J (2012) 0.77
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science (1997) 15.25
Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science (1996) 12.23
Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. J Exp Med (1995) 10.91
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ (2008) 10.45
The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant. Nat Cell Biol (2000) 9.87
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ (2011) 9.44
Fas ligand-induced apoptosis as a mechanism of immune privilege. Science (1995) 8.23
Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner. J Cell Biol (1999) 6.24
Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome. Nat Cell Biol (2000) 5.24
Protease activation during apoptosis: death by a thousand cuts? Cell (1995) 5.15
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J (1998) 5.05
Apoptotic cell death induced by c-myc is inhibited by bcl-2. Nature (1992) 4.75
Breaking the mitochondrial barrier. Nat Rev Mol Cell Biol (2001) 3.63
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ (2009) 3.44
Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes. Nature (1989) 3.23
Mechanisms of p53-dependent apoptosis. Biochem Soc Trans (2001) 2.96
Pro-caspase-3 is a major physiologic target of caspase-8. J Biol Chem (1998) 2.93
Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas. Science (1992) 2.90
The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol. J Cell Biol (1999) 2.85
Contrasuppression. A novel immunoregulatory activity. J Exp Med (1981) 2.84
DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1. Mol Cell (1998) 2.81
Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium. Proc Natl Acad Sci U S A (1997) 2.80
Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J Biol Chem (1999) 2.76
Proteolysis of fodrin (non-erythroid spectrin) during apoptosis. J Biol Chem (1995) 2.67
Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL. J Biol Chem (1999) 2.65
The machinery of programmed cell death. Pharmacol Ther (2001) 2.58
HIV-1 Vpr suppresses immune activation and apoptosis through regulation of nuclear factor kappa B. Nat Med (1997) 2.56
Overlapping cleavage motif selectivity of caspases: implications for analysis of apoptotic pathways. Cell Death Differ (2007) 2.48
Dissecting p53-dependent apoptosis. Cell Death Differ (2006) 2.44
Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario. Cell Death Differ (2006) 2.38
Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system. EMBO J (1997) 2.35
The end of the (cell) line: methods for the study of apoptosis in vitro. Methods Cell Biol (1995) 2.32
Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process. J Cell Biol (2001) 2.29
Activation-induced cell death in T cell hybridomas is due to apoptosis. Morphologic aspects and DNA fragmentation. J Immunol (1990) 2.26
Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death. Mol Cell Biol (1999) 2.25
Dominant-negative p53 mutations in rheumatoid arthritis. Arthritis Rheum (1999) 2.18
p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release. J Biol Chem (2000) 2.14
CD95-induced apoptosis of lymphocytes in an immune privileged site induces immunological tolerance. Immunity (1996) 2.06
Immunoregulatory T-cell pathways. Annu Rev Immunol (1983) 2.06
Rheumatoid arthritis and p53: how oxidative stress might alter the course of inflammatory diseases. Immunol Today (2000) 2.03
Stress management - heat shock protein-70 and the regulation of apoptosis. Trends Cell Biol (2001) 2.02
Establishment of a cell-free system of neuronal apoptosis: comparison of premitochondrial, mitochondrial, and postmitochondrial phases. J Neurosci (1997) 2.01
Training predelinquent youths and their parents to negotiate conflict situations. J Appl Behav Anal (1974) 2.01
In vivo administration of monoclonal antibodies to the CD3 T cell receptor complex induces cell death (apoptosis) in immature thymocytes. J Immunol (1991) 2.00
Changes in endoplasmic reticulum luminal environment affect cell sensitivity to apoptosis. J Cell Biol (2000) 1.98
Human lung carcinomas express Fas ligand. Cancer Res (1997) 1.94
Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation. J Biol Chem (1999) 1.87
Dicing with death: dissecting the components of the apoptosis machinery. Trends Biochem Sci (1994) 1.85
Cell-free reconstitution of Fas-, UV radiation- and ceramide-induced apoptosis. EMBO J (1995) 1.85
Inhibition of TNF-induced apoptosis by NF-kappa B. Trends Cell Biol (1998) 1.84
Caspases induce cytochrome c release from mitochondria by activating cytosolic factors. J Biol Chem (1999) 1.81
Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid. Mol Cell Biol (2000) 1.78
Caspase-independent cell death: leaving the set without the final cut. Oncogene (2008) 1.74
Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax. J Exp Med (2000) 1.73
Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity. J Biol Chem (1996) 1.72
Elevated von Willebrand factor antigen is an early plasma predictor of acute lung injury in nonpulmonary sepsis syndrome. J Clin Invest (1990) 1.71
BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death. Blood (1994) 1.68
Cytochrome c is released in a single step during apoptosis. Cell Death Differ (2005) 1.61
Living with death: the evolution of the mitochondrial pathway of apoptosis in animals. Cell Death Differ (2008) 1.57
Characterization of two different Ly-1+ T cell populations that mediate delayed-type hypersensitivity. J Immunol (1984) 1.55
Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis. J Exp Med (1996) 1.52
Fas and Fas ligand in gut and liver. Am J Physiol Gastrointest Liver Physiol (2000) 1.47
Novel roles for GAPDH in cell death and carcinogenesis. Cell Death Differ (2009) 1.47
Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo. Int Immunol (1995) 1.47
Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3. Blood (1998) 1.42
Immunoregulatory circuits which modulate responsiveness to suppressor cell signals: characterization of an effector cell in the contrasuppressor circuit. Eur J Immunol (1981) 1.40
Degradation of retinoblastoma protein in tumor necrosis factor- and CD95-induced cell death. J Biol Chem (1997) 1.40
Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kappaB. J Biol Chem (1999) 1.39
Analysis of the p53 tumor suppressor gene in rheumatoid arthritis synovial fibroblasts. Arthritis Rheum (1999) 1.39
A genetic herd-immunity model for the maintenance of MHC polymorphism. Immunol Rev (1995) 1.38
Microfilament-disrupting agents prevent the formation of apoptotic bodies in tumor cells undergoing apoptosis. Cancer Res (1992) 1.37
Bcl-2-independent Bcr-Abl-mediated resistance to apoptosis: protection is correlated with up regulation of Bcl-xL. Oncogene (1998) 1.37
Microenvironmental immunoregulation: possible role of contrasuppressor cells in maintaining immune responses in gut-associated lymphoid tissues. Proc Natl Acad Sci U S A (1982) 1.37
Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7. J Biol Chem (1998) 1.34
Calpain activation is upstream of caspases in radiation-induced apoptosis. Cell Death Differ (1998) 1.31
The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by up-regulating Fas ligand expression. J Immunol (1998) 1.31
Immunoregulatory circuits that modulate responsiveness to suppressor cell signal. Failure of B10 mice to respond to suppressor factors can be overcome by quenching the contrasuppressor circuit. J Exp Med (1981) 1.31
Apoptosis and cancer: the failure of controls on cell death and cell survival. Crit Rev Oncol Hematol (1995) 1.29
Inducible nonlymphoid expression of Fas ligand is responsible for superantigen-induced peripheral deletion of T cells. Immunity (1998) 1.26
Anti-apoptotic oncogenes prevent caspase-dependent and independent commitment for cell death. Cell Death Differ (1998) 1.26
How cells die: apoptosis pathways. J Allergy Clin Immunol (2001) 1.24
Calpain functions in a caspase-independent manner to promote apoptosis-like events during platelet activation. Blood (1999) 1.24
Protein kinase ctheta cooperates with calcineurin to induce Fas ligand expression during activation-induced T cell death. J Immunol (1999) 1.24
Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway. J Biol Chem (2001) 1.24
Caspase-2: the orphan caspase. Cell Death Differ (2011) 1.23
Glucose deprivation induces an atypical form of apoptosis mediated by caspase-8 in Bax-, Bak-deficient cells. Cell Death Differ (2010) 1.21
The induction of apoptosis by chemotherapeutic agents occurs in all phases of the cell cycle. Anticancer Res (1992) 1.20
A single cell analysis of apoptosis. Ordering the apoptotic phenotype. Ann N Y Acad Sci (2000) 1.20
Fas ligand- mediated killing by intestinal intraepithelial lymphocytes. Participation in intestinal graft-versus-host disease. J Clin Invest (1998) 1.20
Mitochondrial functions during cell death, a complex (I-V) dilemma. Cell Death Differ (2003) 1.20
Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils. Proc Natl Acad Sci U S A (1994) 1.19
The 'harmless' release of cytochrome c. Cell Death Differ (2000) 1.18
p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation. Cell Death Differ (2003) 1.16
Risk factors and the incidence of hypertension in black physicians: the Meharry Cohort Study. Am Heart J (1985) 1.14
Transforming growth factor beta1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via downregulation of c-Myc. J Exp Med (1999) 1.14
Genetic deletion of caspase-2 accelerates MMTV/c-neu-driven mammary carcinogenesis in mice. Cell Death Differ (2013) 1.13
Precursors of hypertension in black medical students: the Meharry cohort study. J Natl Med Assoc (1984) 1.12
Isotype-specific immunoregulation. Evidence for a distinct subset of T contrasuppressor cells for IgA responses in murine Peyer's patches. J Exp Med (1986) 1.11
Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity. J Biol Chem (2001) 1.11