Dominant-negative p53 mutations in rheumatoid arthritis.

PubWeight™: 2.18‹?› | Rank: Top 2%

🔗 View Article (PMID 10366100)

Published in Arthritis Rheum on June 01, 1999

Authors

Z Han1, D L Boyle, Y Shi, D R Green, G S Firestein

Author Affiliations

1: University of California, San Diego, School of Medicine, La Jolla 92093-0656, USA.

Articles citing this

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis. Immunol Rev (2010) 4.48

Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors. Nat Rev Rheumatol (2012) 2.24

Regional analysis of p53 mutations in rheumatoid arthritis synovium. Proc Natl Acad Sci U S A (2002) 2.19

Genetics of rheumatoid arthritis: confronting complexity. Arthritis Res (1999) 1.63

Regulation of joint destruction and inflammation by p53 in collagen-induced arthritis. Am J Pathol (2002) 1.58

Molecular profile of synovial fibroblasts in rheumatoid arthritis depends on the stage of proliferation. Arthritis Res (2002) 1.19

Absence of p53 mutation in Japanese patients with rheumatoid arthritis: comment on the article by Han et al. Arthritis Rheum (2000) 1.11

Discrepancy between mRNA and protein expression of tumour suppressor maspin in synovial tissue may contribute to synovial hyperplasia in rheumatoid arthritis. Ann Rheum Dis (2004) 0.99

PUMA-mediated apoptosis in fibroblast-like synoviocytes does not require p53. Arthritis Res Ther (2006) 0.97

p53 tumor suppressor gene mutations in fibroblast-like synoviocytes from erosion synovium and non-erosion synovium in rheumatoid arthritis. Arthritis Res Ther (2004) 0.95

Detection of oncofetal h19 RNA in rheumatoid arthritis synovial tissue. Am J Pathol (2003) 0.94

Apoptosis of rheumatoid arthritis fibroblast-like synoviocytes: possible roles of nitric oxide and the thioredoxin 1. Mediators Inflamm (2013) 0.94

Regulation of rheumatoid synoviocyte proliferation by endogenous p53 induction. Clin Exp Immunol (2001) 0.86

p53 in rheumatoid arthritis: friend or foe? Arthritis Res (2000) 0.85

TP53 mutations coincide with the ectopic expression of activation-induced cytidine deaminase in the fibroblast-like synoviocytes derived from a fraction of patients with rheumatoid arthritis. Clin Exp Immunol (2010) 0.83

The danger model approach to the pathogenesis of the rheumatic diseases. J Immunol Res (2015) 0.81

The p53 status in juvenile chronic arthritis and rheumatoid arthritis. Clin Exp Immunol (2000) 0.80

The proto-oncogene survivin splice variant 2B is induced by PDGF and leads to cell proliferation in rheumatoid arthritis fibroblast-like synoviocytes. Sci Rep (2015) 0.79

Over-expression of TATA binding protein (TBP) and p53 and autoantibodies to these antigens are features of systemic sclerosis, systemic lupus erythematosus and overlap syndromes. Clin Exp Immunol (2004) 0.79

p53 predominantly regulates IL-6 production and suppresses synovial inflammation in fibroblast-like synoviocytes and adjuvant-induced arthritis. Arthritis Res Ther (2016) 0.77

The gain of function of p53 mutant p53S in promoting tumorigenesis by cross-talking with H-RasV12. Int J Biol Sci (2012) 0.76

Molecular mechanism leading to SAHA-induced autophagy in tumor cells: evidence for a p53-dependent pathway. Cancer Cell Int (2016) 0.75

Pubertal and adult windows of susceptibility to a high animal fat diet in Trp53-null mammary tumorigenesis. Oncotarget (2016) 0.75

Efficacy of Adoptive T-cell Therapy Is Improved by Treatment with the Antioxidant N-Acetyl Cysteine, Which Limits Activation-Induced T-cell Death. Cancer Res (2016) 0.75

The Double Role of p53 in Cancer and Autoimmunity and Its Potential as Therapeutic Target. Int J Mol Sci (2016) 0.75

Articles by these authors

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science (1997) 15.25

Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science (1996) 12.23

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. J Exp Med (1995) 10.91

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ (2008) 10.45

The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant. Nat Cell Biol (2000) 9.87

NF-kappaB: a key role in inflammatory diseases. J Clin Invest (2001) 9.66

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ (2011) 9.44

Fas ligand-induced apoptosis as a mechanism of immune privilege. Science (1995) 8.23

Relationship between medication errors and adverse drug events. J Gen Intern Med (1995) 7.81

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis. Nature (2001) 6.62

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell (1999) 6.59

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner. J Cell Biol (1999) 6.24

The galvanization of biology: a growing appreciation for the roles of zinc. Science (1996) 5.67

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome. Nat Cell Biol (2000) 5.24

Protease activation during apoptosis: death by a thousand cuts? Cell (1995) 5.15

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J (1998) 5.05

Apoptotic cell death induced by c-myc is inhibited by bcl-2. Nature (1992) 4.75

CREB-binding protein/p300 are transcriptional coactivators of p65. Proc Natl Acad Sci U S A (1997) 4.71

YY1 is an initiator sequence-binding protein that directs and activates transcription in vitro. Nature (1991) 4.30

Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant. Nature (2000) 4.01

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. J Clin Invest (2001) 3.86

Structural basis of IAP recognition by Smac/DIABLO. Nature (2001) 3.66

Breaking the mitochondrial barrier. Nat Rev Mol Cell Biol (2001) 3.63

Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature (2000) 3.54

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ (2009) 3.44

The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1. J Virol (2000) 3.43

Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes. Nature (1989) 3.23

Evidence for physical interaction between the zinc-finger transcription factors YY1 and Sp1. Proc Natl Acad Sci U S A (1993) 3.09

Suicidal tendencies: apoptotic cell death by caspase family proteinases. J Biol Chem (1999) 3.04

Structural basis of caspase-7 inhibition by XIAP. Cell (2001) 2.99

Mechanisms of p53-dependent apoptosis. Biochem Soc Trans (2001) 2.96

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1. Nature (1999) 2.95

Pro-caspase-3 is a major physiologic target of caspase-8. J Biol Chem (1998) 2.93

Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300. Genes Dev (1995) 2.93

Impact of computerized physician order entry on physician time. Proc Annu Symp Comput Appl Med Care (1994) 2.93

Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas. Science (1992) 2.90

The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol. J Cell Biol (1999) 2.85

Contrasuppression. A novel immunoregulatory activity. J Exp Med (1981) 2.84

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. Proc Natl Acad Sci U S A (2001) 2.83

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1. Mol Cell (1998) 2.81

Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium. Proc Natl Acad Sci U S A (1997) 2.80

Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J Biol Chem (1999) 2.76

Dentinogenesis imperfecta 1 with or without progressive hearing loss is associated with distinct mutations in DSPP. Nat Genet (2001) 2.75

Proteolysis of fodrin (non-erythroid spectrin) during apoptosis. J Biol Chem (1995) 2.67

Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL. J Biol Chem (1999) 2.65

Targeted disruption of mouse Yin Yang 1 transcription factor results in peri-implantation lethality. Mol Cell Biol (1999) 2.61

The machinery of programmed cell death. Pharmacol Ther (2001) 2.58

HIV-1 Vpr suppresses immune activation and apoptosis through regulation of nuclear factor kappa B. Nat Med (1997) 2.56

Overlapping cleavage motif selectivity of caspases: implications for analysis of apoptotic pathways. Cell Death Differ (2007) 2.48

Dissecting p53-dependent apoptosis. Cell Death Differ (2006) 2.44

Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding. Cell (2001) 2.39

Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario. Cell Death Differ (2006) 2.38

Predicting clopidogrel response using DNA samples linked to an electronic health record. Clin Pharmacol Ther (2011) 2.36

Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system. EMBO J (1997) 2.35

The end of the (cell) line: methods for the study of apoptosis in vitro. Methods Cell Biol (1995) 2.32

Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process. J Cell Biol (2001) 2.29

Activation-induced cell death in T cell hybridomas is due to apoptosis. Morphologic aspects and DNA fragmentation. J Immunol (1990) 2.26

Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death. Mol Cell Biol (1999) 2.25

Apoptosome: a platform for the activation of initiator caspases. Cell Death Differ (2006) 2.25

Determinants of specificity in TGF-beta signal transduction. Genes Dev (1998) 2.23

The AKT kinase is activated in multiple myeloma tumor cells. Blood (2001) 2.20

Cytokines in chronic inflammatory arthritis. II. Granulocyte-macrophage colony-stimulating factor in rheumatoid synovial effusions. J Clin Invest (1989) 2.18

Displacement of BrdUrd-induced YY1 by serum response factor activates skeletal alpha-actin transcription in embryonic myoblasts. Proc Natl Acad Sci U S A (1992) 2.15

What proportion of common diagnostic tests appear redundant? Am J Med (1998) 2.15

p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release. J Biol Chem (2000) 2.14

Cytokines in chronic inflammatory arthritis. VI. Analysis of the synovial cells involved in granulocyte-macrophage colony-stimulating factor production and gene expression in rheumatoid arthritis and its regulation by IL-1 and tumor necrosis factor-alpha. J Immunol (1991) 2.09

AP-1 and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis. Autoimmunity (1998) 2.09

The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism. EMBO J (1996) 2.09

Alpha 4/beta 1 integrin (VLA-4) ligands in arthritis. Vascular cell adhesion molecule-1 expression in synovium and on fibroblast-like synoviocytes. J Immunol (1992) 2.08

CD95-induced apoptosis of lymphocytes in an immune privileged site induces immunological tolerance. Immunity (1996) 2.06

Yin-yang 1 activates the c-myc promoter. Mol Cell Biol (1993) 2.06

Immunoregulatory T-cell pathways. Annu Rev Immunol (1983) 2.06

Peripheral blood and synovial fluid monocyte activation in inflammatory arthritis. II. Low levels of synovial fluid and synovial tissue interferon suggest that gamma-interferon is not the primary macrophage activating factor. Arthritis Rheum (1987) 2.04

Rheumatoid arthritis and p53: how oxidative stress might alter the course of inflammatory diseases. Immunol Today (2000) 2.03

Coexisting stable conformations of gaseous protein ions. Proc Natl Acad Sci U S A (1993) 2.03

Stress management - heat shock protein-70 and the regulation of apoptosis. Trends Cell Biol (2001) 2.02

Training predelinquent youths and their parents to negotiate conflict situations. J Appl Behav Anal (1974) 2.01

Establishment of a cell-free system of neuronal apoptosis: comparison of premitochondrial, mitochondrial, and postmitochondrial phases. J Neurosci (1997) 2.01

In vivo administration of monoclonal antibodies to the CD3 T cell receptor complex induces cell death (apoptosis) in immature thymocytes. J Immunol (1991) 2.00

Changes in endoplasmic reticulum luminal environment affect cell sensitivity to apoptosis. J Cell Biol (2000) 1.98

Cytokines in chronic inflammatory arthritis. V. Mutual antagonism between interferon-gamma and tumor necrosis factor-alpha on HLA-DR expression, proliferation, collagenase production, and granulocyte macrophage colony-stimulating factor production by rheumatoid arthritis synoviocytes. J Clin Invest (1990) 1.97

Adeno-associated virus P5 promoter contains an adenovirus E1A-inducible element and a binding site for the major late transcription factor. J Virol (1989) 1.96

Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling. Mol Cell (2001) 1.95

Human lung carcinomas express Fas ligand. Cancer Res (1997) 1.94

The 1.9 A crystal structure of Escherichia coli MurG, a membrane-associated glycosyltransferase involved in peptidoglycan biosynthesis. Protein Sci (2000) 1.90

Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis. J Immunol (1995) 1.89

Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation. J Biol Chem (1999) 1.87

Physicochemical and microbiological properties of selected rice flour-based batters for fried chicken drumsticks. Poult Sci (2001) 1.86

Dicing with death: dissecting the components of the apoptosis machinery. Trends Biochem Sci (1994) 1.85

Cell-free reconstitution of Fas-, UV radiation- and ceramide-induced apoptosis. EMBO J (1995) 1.85

Inhibition of TNF-induced apoptosis by NF-kappa B. Trends Cell Biol (1998) 1.84

Heat shock protein 90 mediates the balance of nitric oxide and superoxide anion from endothelial nitric-oxide synthase. J Biol Chem (2001) 1.82

DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells. Proc Natl Acad Sci U S A (2000) 1.82

Synergistic benefit in inflammatory arthritis by targeting I kappaB kinase epsilon and interferon beta. Ann Rheum Dis (2008) 1.82