Published in J Mol Biol on August 06, 1999
Assessing the accuracy of ancestral protein reconstruction methods. PLoS Comput Biol (2006) 1.62
The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases. Proc Natl Acad Sci U S A (2006) 1.39
Amino acid coevolution induces an evolutionary Stokes shift. Proc Natl Acad Sci U S A (2012) 1.35
Phosphate forms an unusual tripodal complex with the Fe-Mn center of sweet potato purple acid phosphatase. Proc Natl Acad Sci U S A (2004) 1.12
The human Vps29 retromer component is a metallo-phosphoesterase for a cation-independent mannose 6-phosphate receptor substrate peptide. Biochem J (2006) 1.09
Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycle. BMC Struct Biol (2008) 0.91
Nonadaptive Amino Acid Convergence Rates Decrease over Time. Mol Biol Evol (2015) 0.91
Population size dependence of fitness effect distribution and substitution rate probed by biophysical model of protein thermostability. Genome Biol Evol (2013) 0.88
Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes. J Am Chem Soc (2008) 0.84
The reaction mechanism of the Ga(III)Zn(II) derivative of uteroferrin and corresponding biomimetics. J Biol Inorg Chem (2007) 0.81
The structure of a purple acid phosphatase involved in plant growth and pathogen defence exhibits a novel immunoglobulin-like fold. IUCrJ (2014) 0.79
Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.79
Direct observation of multiple protonation states in recombinant human purple acid phosphatase. J Biol Inorg Chem (2005) 0.77
A new heterobinuclear FeIIICuII complex with a single terminal FeIII-O(phenolate) bond. Relevance to purple acid phosphatases and nucleases. J Biol Inorg Chem (2005) 0.76
The tangled bank of amino acids. Protein Sci (2016) 0.76
Accelerated simulation of evolutionary trajectories in origin-fixation models. J R Soc Interface (2017) 0.75
Theoretical studies on the mechanism of activation of phosphoprotein phosphatases and purple acid phosphatases suggest an evolutionary strategy to survive in acidic environments. J Biol Inorg Chem (2013) 0.75
Sequence entropy of folding and the absolute rate of amino acid substitutions. Nat Ecol Evol (2017) 0.75
[Gibberellins. XLIII. Part. Fractionation of gibberellins, gibberellin conjugates and other plant hormones through DEAE-Sephadex chromatography]. J Chromatogr (1976) 6.41
Randomised trial of Haemophilus influenzae type-b tetanus protein conjugate vaccine [corrected] for prevention of pneumonia and meningitis in Gambian infants. Lancet (1997) 4.32
Roles of yeast DNA polymerases delta and zeta and of Rev1 in the bypass of abasic sites. Genes Dev (2001) 3.59
Glycoproteins of the lysosomal membrane. J Cell Biol (1985) 3.46
Longer delays in tuberculosis diagnosis among women in Vietnam. Int J Tuberc Lung Dis (1999) 3.30
A trial of artemether or quinine in children with cerebral malaria. N Engl J Med (1996) 3.28
Colorectal carcinoma associated with serrated adenoma--prevalence, histological features, and prognosis. J Pathol (2001) 3.24
Crystal structure of delta9 stearoyl-acyl carrier protein desaturase from castor seed and its relationship to other di-iron proteins. EMBO J (1996) 2.84
Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed. Science (1999) 2.62
The outer membrane of yeast mitochondria: isolation of outside-out sealed vesicles. EMBO J (1983) 2.48
Rotational diffusion of band 3 proteins in the human erythrocyte membrane. Nature (1976) 2.22
Computed tomography of cryogenic biological specimens based on X-ray microscopic images. Ultramicroscopy (2000) 2.14
Fear and social isolation as consequences of tuberculosis in VietNam: a gender analysis. Health Policy (2001) 2.12
[On a bound gibberellin from Phaseolus coccineus L]. Experientia (1964) 2.05
Circular permutations of natural protein sequences: structural evidence. Curr Opin Struct Biol (1997) 2.04
Deciphering apicoplast targeting signals--feature extraction from nuclear-encoded precursors of Plasmodium falciparum apicoplast proteins. Gene (2001) 1.96
Concordant genotype of upper and lower airways P aeruginosa and S aureus isolates in cystic fibrosis. Thorax (2009) 1.90
Increased estrogen production in obese men. J Clin Endocrinol Metab (1979) 1.89
Endoscopic surgery versus medical treatment for spontaneous intracerebral hematoma: a randomized study. J Neurosurg (1989) 1.89
Three-dimensional structure of transketolase, a thiamine diphosphate dependent enzyme, at 2.5 A resolution. EMBO J (1992) 1.87
Residual neurologic sequelae after childhood cerebral malaria. J Pediatr (1997) 1.84
Microsatellite instability: impact on cancer progression in proximal and distal colorectal cancers. Eur J Cancer (1999) 1.82
Three-dimensional structure of a mammalian thioredoxin reductase: implications for mechanism and evolution of a selenocysteine-dependent enzyme. Proc Natl Acad Sci U S A (2001) 1.80
Regression of warts. An immunological study. Lancet (1975) 1.78
Increasing isoflurane concentration may cause paradoxical increases in the EEG bispectral index in surgical patients. Br J Anaesth (2000) 1.76
Detection of hematogenous micrometastasis in patients with prostate cancer. Cancer Res (1992) 1.75
How thiamine diphosphate is activated in enzymes. Science (1997) 1.69
Crystal structure of nitrile hydratase reveals a novel iron centre in a novel fold. Structure (1997) 1.68
The effect of a monoclonal antibody to tumor necrosis factor on survival from childhood cerebral malaria. J Infect Dis (1996) 1.62
Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase. J Biol Chem (1999) 1.58
Direct association of protein-tyrosine phosphatase PTP-PEST with paxillin. J Biol Chem (1998) 1.51
Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence. J Biol Chem (2001) 1.50
Scaffold architecture and pharmacophoric properties of natural products and trade drugs: application in the design of natural product-based combinatorial libraries. J Comb Chem (2001) 1.49
Prevalence of black-pigmented bacteroides species in root canal infections. J Endod (1989) 1.49
A spectroscopic technique for measuring slow rotational diffusion of macromolecules. 1: Preparation and properties of a triplet probe. Biochemistry (1976) 1.47
Predictors of a fatal outcome following childhood cerebral malaria. Am J Trop Med Hyg (1997) 1.46
Crystal structure of beta-ketoacyl-acyl carrier protein synthase II from E.coli reveals the molecular architecture of condensing enzymes. EMBO J (1998) 1.46
The clinical spectrum of respiratory syncytial virus disease in The Gambia. Pediatr Infect Dis J (1998) 1.45
Scientific rigour in qualitative research--examples from a study of women's health in family practice. Fam Pract (1994) 1.44
Different tuberculosis in men and women: beliefs from focus groups in Vietnam. Soc Sci Med (1999) 1.43
Circinate erosive balanitis and HL-A 27. Acta Derm Venereol (1975) 1.42
Antibiotic treatment of symptomatic Mycoplasma genitalium infection in Scandinavia: a controlled clinical trial. Sex Transm Infect (2007) 1.42
The crystal structure of phenol hydroxylase in complex with FAD and phenol provides evidence for a concerted conformational change in the enzyme and its cofactor during catalysis. Structure (1998) 1.42
Functional interaction between the Werner Syndrome protein and DNA polymerase delta. Proc Natl Acad Sci U S A (2000) 1.42
Monitors of the hypnotic component of anesthesia - correlation between bispectral index and cerebral state index. Minerva Anestesiol (2012) 1.41
Eukaryotic expression: developments for structural proteomics. Acta Crystallogr D Biol Crystallogr (2006) 1.41
Two infants with life-threatening diffuse neonatal hemangiomatosis treated with cyclophosphamide. Pediatr Blood Cancer (2006) 1.41
High resolution crystal structure of pyruvate decarboxylase from Zymomonas mobilis. Implications for substrate activation in pyruvate decarboxylases. J Biol Chem (1998) 1.41
First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value. Acta Crystallogr D Biol Crystallogr (2006) 1.40
Molecular epidemiological typing within the European Gonococcal Antimicrobial Resistance Surveillance Programme reveals predominance of a multidrug-resistant clone. Euro Surveill (2013) 1.39
Effects of tumour mass and circulating antigen on the biodistribution of 111In-labelled F(ab')2 fragments of human prostatic acid phosphatase monoclonal antibody in nude mice bearing PC-82 human prostatic tumour xenografts. Eur J Nucl Med (1991) 1.38
Two new male contraceptives exert their effects by depleting germ cells prematurely from the testis. Biol Reprod (2001) 1.34
Crystal structure of transaldolase B from Escherichia coli suggests a circular permutation of the alpha/beta barrel within the class I aldolase family. Structure (1996) 1.31
Redesign of soluble fatty acid desaturases from plants for altered substrate specificity and double bond position. Proc Natl Acad Sci U S A (1997) 1.31
Differentially expressed genes in two LNCaP prostate cancer cell lines reflecting changes during prostate cancer progression. Lab Invest (2000) 1.30
Suppression of cell-mediated immune responses to malaria antigens in pregnant Gambian women. Am J Trop Med Hyg (1989) 1.30
A thiamin diphosphate binding fold revealed by comparison of the crystal structures of transketolase, pyruvate oxidase and pyruvate decarboxylase. Structure (1993) 1.26
Androgen-estrogen metabolism in women with upper body versus lower body obesity. J Clin Endocrinol Metab (1990) 1.26
HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA. Gut (2009) 1.26
A spectroscopic technique for measuring slow rotational diffusion of macromolecules. 2: Determination of rotational correlation times of proteins in solution. Biochemistry (1976) 1.26
Gonorrhea, genital chlamydial infection, and nonspecific urethritis in male partners of women hospitalized and treated for acute pelvic inflammatory disease. Sex Transm Dis (1993) 1.24
Plant hormone conjugation. Plant Mol Biol (1994) 1.24
The crystal structure of H-2Dd MHC class I complexed with the HIV-1-derived peptide P18-I10 at 2.4 A resolution: implications for T cell and NK cell recognition. Immunity (1998) 1.23
The epidemiology of Haemophilus influenzae meningitis in children under five years of age in The Gambia, West Africa. J Infect Dis (1990) 1.22
Nutritional status of children admitted to hospital with different diseases and its relationship to outcome in The Gambia, West Africa. Trop Med Int Health (1998) 1.22
Ganciclovir and acyclovir reduce the risk of post-transplant lymphoproliferative disorder in renal transplant recipients. Am J Transplant (2005) 1.22
The TMPRSS2 gene encoding transmembrane serine protease is overexpressed in a majority of prostate cancer patients: detection of mutated TMPRSS2 form in a case of aggressive disease. Int J Cancer (2001) 1.21
Rotational diffusion of bacteriorhodopsin in lipid membranes. FEBS Lett (1977) 1.21
Clomiphene citrate administration to normogonadotropic subfertile men: blood hormone changes and activation of acid phosphatase in seminal fluid. Int J Androl (1981) 1.20
Intracellular fragmentation of bone resorption products by reactive oxygen species generated by osteoclastic tartrate-resistant acid phosphatase. J Biol Chem (1999) 1.19
Crystal structure of the FAD-containing fragment of corn nitrate reductase at 2.5 A resolution: relationship to other flavoprotein reductases. Structure (1994) 1.19
Topography of callosal atrophy reflects distribution of regional cerebral volume reduction in Alzheimer's disease. Psychiatry Res (1999) 1.18
Immunohistochemical and electron microscopic characterization of the cellular infiltrate in alopecia (areata, totalis, and universalis). J Invest Dermatol (1984) 1.17
Autophagic vacuoles fuse with the prelysosomal compartment in cultured rat fibroblasts. Eur J Cell Biol (1993) 1.17
Epidemiology of invasive pneumococcal disease in the Western Region, The Gambia. Pediatr Infect Dis J (1998) 1.17
HMG I(Y) interferes with the DNA binding of NF-AT factors and the induction of the interleukin 4 promoter in T cells. Proc Natl Acad Sci U S A (1996) 1.17
The three-dimensional structure of human transaldolase. FEBS Lett (2000) 1.17
Crystal structure of the ternary complex of ribulose-1,5-bisphosphate carboxylase, Mg(II), and activator CO2 at 2.3-A resolution. Biochemistry (1991) 1.16
Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracil. EMBO J (2001) 1.16
Examination of substrate binding in thiamin diphosphate-dependent transketolase by protein crystallography and site-directed mutagenesis. J Biol Chem (1997) 1.15
Missing cruciate ligament in congenital short femur. J Bone Joint Surg Am (1983) 1.14
P fimbriae-dependent, lipopolysaccharide-independent activation of epithelial cytokine responses. Mol Microbiol (1999) 1.14
Crystal structure of diaminopelargonic acid synthase: evolutionary relationships between pyridoxal-5'-phosphate-dependent enzymes. J Mol Biol (1999) 1.14
Pathogenesis of rabies and rabies-like viruses. Ann Inst Pasteur (Paris) (1972) 1.14
Bactericidal effect of pooled human serum on Bacteroides melaninogenicus, Bacteroides asaccharolyticus and Actinobacillus actinomycetemcomitans. Scand J Dent Res (1982) 1.14
Refined structure of transketolase from Saccharomyces cerevisiae at 2.0 A resolution. J Mol Biol (1994) 1.13
Community perceptions of tuberculosis: A qualitative exploration from a gender perspective. Public Health (2011) 1.12
Crystal structure of the reduced Schiff-base intermediate complex of transaldolase B from Escherichia coli: mechanistic implications for class I aldolases. Protein Sci (1997) 1.11
Multicentre comparison of skin hydration in terms of physical-, physiological- and product-dependent parameters by the capacitive method (Corneometer CM 825). Int J Cosmet Sci (2003) 1.11
The adenovirus type 5 E1B-55K oncoprotein actively shuttles in virus-infected cells, whereas transport of E4orf6 is mediated by a CRM1-independent mechanism. J Virol (2001) 1.11
Three-dimensional structure of rat acid phosphatase. EMBO J (1993) 1.11
A new class of symmetric bisbenzimidazole-based DNA minor groove-binding agents showing antitumor activity. J Med Chem (2001) 1.10
Yeast TKL1 gene encodes a transketolase that is required for efficient glycolysis and biosynthesis of aromatic amino acids. J Biol Chem (1993) 1.10
Screening for carcinoma of the prostate. Rectal examination, and enzymatic and radioimmunologic measurements of serum acid phosphatase compared. Cancer (1985) 1.10
Caudal regression sequence: vascular origin? J Perinatol (2006) 1.09
Effects of progesterone on uterine leiomyoma growth and apoptosis. Steroids (2000) 1.09
Ultrahigh-resolution soft-x-ray microscopy with zone plates in high orders of diffraction. Phys Rev Lett (2009) 1.08