Published in Cancer Res on September 01, 1999
CD44 is required for two consecutive steps in HGF/c-Met signaling. Genes Dev (2002) 3.07
Crossing the endothelial barrier during metastasis. Nat Rev Cancer (2013) 2.00
Stepping out of the flow: capillary extravasation in cancer metastasis. Clin Exp Metastasis (2007) 1.68
Development of a peptide inhibitor of hyaluronan-mediated leukocyte trafficking. J Exp Med (2000) 1.65
CD44 enhances neuregulin signaling by Schwann cells. J Cell Biol (2000) 1.38
CD44v4 is a major E-selectin ligand that mediates breast cancer cell transendothelial migration. PLoS One (2008) 1.36
Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer. Cancer Res (2012) 1.31
Circulating galectin-3 promotes metastasis by modifying MUC1 localization on cancer cell surface. Cancer Res (2009) 1.26
Enhancive effects of Lewis y antigen on CD44-mediated adhesion and spreading of human ovarian cancer cell line RMG-I. J Exp Clin Cancer Res (2011) 1.08
Characteristics of CD44 alternative splice pattern in the course of human colorectal adenocarcinoma progression. Mol Cancer (2012) 1.04
αB-crystallin: a novel regulator of breast cancer metastasis to the brain. Clin Cancer Res (2013) 1.02
Dentin matrix protein 1 enhances invasion potential of colon cancer cells by bridging matrix metalloproteinase-9 to integrins and CD44. Cancer Res (2005) 0.98
CD44-mediated phagocytosis induces inside-out activation of complement receptor-3 in murine macrophages. Blood (2007) 0.97
ICAM-1 mediated peritoneal carcinomatosis, a target for therapeutic intervention. Clin Exp Metastasis (2005) 0.95
Expression and significance of CD44, CD47 and c-met in ovarian clear cell carcinoma. Int J Mol Sci (2015) 0.94
Prognostic significance of CD44s expression in resected non-small cell lung cancer. BMC Cancer (2011) 0.94
Dynamic study of the transition from hyaluronan- to integrin-mediated adhesion in chondrocytes. EMBO J (2006) 0.91
Three-dimensional growth as multicellular spheroid activates the proangiogenic phenotype of colorectal carcinoma cells via LFA-1-dependent VEGF: implications on hepatic micrometastasis. J Transl Med (2008) 0.91
Modulation of hyaluronan production by CD44 positive glioma cells. Int J Cancer (2010) 0.90
α7 helix region of αI domain is crucial for integrin binding to endoplasmic reticulum chaperone gp96: a potential therapeutic target for cancer metastasis. J Biol Chem (2013) 0.85
CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 status. PLoS One (2013) 0.83
Hyaluronan regulation of endothelial barrier function in cancer. Adv Cancer Res (2014) 0.83
Levels of v5 and v6 CD44 splice variants in serum of patients with colorectal cancer are not correlated with pT stage, histopathological grade of malignancy and clinical features. World J Gastroenterol (2004) 0.82
Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes. BMC Cancer (2007) 0.81
Protection of trocar sites from gallbladder cancer implantation by sodium hyaluronate carboxymethylcellulose-based bioresorbable membrane (Seprafilm) in a murine model [corrected]. Surg Endosc (2003) 0.81
The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines. Sci Rep (2015) 0.81
TNFalpha and IL-8 regulate the expression and function of CD44 variant proteins in human colon carcinoma cells. Clin Exp Metastasis (2002) 0.80
Melanoma upregulates ICAM-1 expression on endothelial cells through engagement of tumor CD44 with endothelial E-selectin and activation of a PKCα-p38-SP-1 pathway. FASEB J (2014) 0.80
Mechanisms of interferon-γ production by neutrophils and its function during Streptococcus pneumoniae pneumonia. Am J Respir Cell Mol Biol (2015) 0.80
Pathophysiology of colorectal peritoneal carcinomatosis: Role of the peritoneum. World J Gastroenterol (2016) 0.79
Interactions between colon cancer cells and hepatocytes in rats in relation to metastasis. J Cell Mol Med (2008) 0.78
CD44-mediated activation of α5β1-integrin, cortactin and paxillin signaling underpins adhesion of basal-like breast cancer cells to endothelium and fibronectin-enriched matrices. Oncotarget (2015) 0.78
Bone Marrow-Derived Stem Cells in Pathogenesis of Helicobacter pylori-Associated Gastrointestinal Cancer. Clin Transl Gastroenterol (2015) 0.75
Effects of hepatocyte growth factor/scatter factor on the invasion of colorectal cancer cells in vitro. World J Gastroenterol (2005) 0.75
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell (2000) 20.83
A protein conjugation system essential for autophagy. Nature (1998) 12.71
The genome of the social amoeba Dictyostelium discoideum. Nature (2005) 9.18
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science (2001) 8.31
Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell (1998) 8.16
Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution. Nature (1995) 7.62
Phenanthrenequinone as an analytical reagent for arginine and other monosubstituted guanidines. Biochim Biophys Acta (1966) 7.11
CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer. Cancer Res (1998) 6.42
MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover. Cell (1999) 6.40
E-CELL: software environment for whole-cell simulation. Bioinformatics (1999) 6.29
Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse. Proc Natl Acad Sci U S A (1991) 5.52
Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3) Nature (1996) 5.32
Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies. Blood (2001) 5.17
Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. J Clin Invest (2000) 5.07
Natural and synthetic non-peptide antigens recognized by human gamma delta T cells. Nature (1995) 5.04
Genetic analysis of novel avian A(H7N9) influenza viruses isolated from patients in China, February to April 2013. Euro Surveill (2013) 4.44
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nat Med (2001) 4.22
An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy. Nature (1998) 3.86
Lack of myocardial perfusion immediately after successful thrombolysis. A predictor of poor recovery of left ventricular function in anterior myocardial infarction. Circulation (1992) 3.73
Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters. J Biol Chem (1983) 3.60
Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta. Cell (2001) 3.49
The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus. Nature (1991) 3.48
Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia. Blood (1999) 3.46
Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion. Science (1998) 3.39
Mini-laparoscopic appendectomy using a needle loop retractor offers optimal cosmetic results. Surg Endosc (2004) 3.38
Lymphocyte interactions with endothelial cells. Immunol Today (1992) 3.31
Intratumoral distribution of fluorine-18-fluorodeoxyglucose in vivo: high accumulation in macrophages and granulation tissues studied by microautoradiography. J Nucl Med (1992) 3.31
Nucleotide sequence homology at 12 intron--exon junctions in the chick ovalbumin gene. Nature (1978) 3.30
Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3. J Biol Chem (1999) 3.25
Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis. J Cell Biol (1999) 3.14
Direct presentation of nonpeptide prenyl pyrophosphate antigens to human gamma delta T cells. Immunity (1995) 3.12
CBP as a transcriptional coactivator of c-Myb. Genes Dev (1996) 3.09
A high-speed atomic force microscope for studying biological macromolecules. Proc Natl Acad Sci U S A (2001) 2.97
Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Valpha14 NKT cells. Proc Natl Acad Sci U S A (1998) 2.96
Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein. J Cell Biol (1998) 2.87
Biological activity of 25-hydroxyergocalciferol in rats. J Nutr (1970) 2.85
Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily gene. Nat Genet (2001) 2.79
Sense, nonsense and antisense. Trends Genet (1994) 2.66
Requirement of CD9 on the egg plasma membrane for fertilization. Science (2000) 2.65
Single molecule imaging of fluorophores and enzymatic reactions achieved by objective-type total internal reflection fluorescence microscopy. Biochem Biophys Res Commun (1997) 2.65
Broad line emission from iron K- and L-shell transitions in the active galaxy 1H 0707-495. Nature (2009) 2.64
Clinical implications of the 'no reflow' phenomenon. A predictor of complications and left ventricular remodeling in reperfused anterior wall myocardial infarction. Circulation (1996) 2.59
Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism. Proc Natl Acad Sci U S A (2001) 2.58
New classification of capsular block syndrome. J Cataract Refract Surg (1998) 2.57
Target cells for 1,25-dihydroxyvitamin D3 in intestinal tract, stomach, kidney, skin, pituitary, and parathyroid. Science (1979) 2.57
Tissue plasminogen activator (tPA) deficiency exacerbates cerebrovascular fibrin deposition and brain injury in a murine stroke model: studies in tPA-deficient mice and wild-type mice on a matched genetic background. Arterioscler Thromb Vasc Biol (1999) 2.56
Abnormal nodal flow precedes situs inversus in iv and inv mice. Mol Cell (1999) 2.55
Nucleotide sequence of the PR-1 gene of Nicotiana tabacum. FEBS Lett (1987) 2.53
The control of 25-hydroxyvitamin D metabolism by inorganic phosphorus. Arch Biochem Biophys (1973) 2.53
Characteristics of macrolide-resistant Mycoplasma pneumoniae strains isolated from patients and induced with erythromycin in vitro. Microbiol Immunol (2001) 2.52
RecQ DNA helicase is a suppressor of illegitimate recombination in Escherichia coli. Proc Natl Acad Sci U S A (1997) 2.51
Cloning and expression of cytochrome P450 genes controlling flower colour. Nature (1993) 2.47
KIF5C, a novel neuronal kinesin enriched in motor neurons. J Neurosci (2000) 2.43
The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation. J Cardiovasc Pharmacol (1996) 2.43
Increased expression of sialyl Lewisx antigen correlates with poor survival in patients with colorectal carcinoma: clinicopathological and immunohistochemical study. Cancer Res (1993) 2.39
Spinal cord injury in a child caused by an accidental dural puncture with a single-shot thoracic epidural needle. Anesth Analg (2003) 2.38
Tumor necrosis factor-alpha (TNF-alpha) plays a protective role in acute viralmyocarditis in mice: A study using mice lacking TNF-alpha. Circulation (2001) 2.36
CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression. Mol Psychiatry (2009) 2.36
Essential role for Gab2 in the allergic response. Nature (2001) 2.32
Myocardial perfusion patterns related to thrombolysis in myocardial infarction perfusion grades after coronary angioplasty in patients with acute anterior wall myocardial infarction. Circulation (1996) 2.31
Translational induction of heat shock transcription factor sigma32: evidence for a built-in RNA thermosensor. Genes Dev (1999) 2.30
A bacterium lipopolysaccharide that elicits Guillain-Barré syndrome has a GM1 ganglioside-like structure. J Exp Med (1993) 2.29
Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity. Oncogene (2007) 2.28
Dynamic expression and essential functions of Hes7 in somite segmentation. Genes Dev (2001) 2.26
Chemical components in the cell wall of Salmonella typhimurium affecting its virulence and immunogenicity in mice. Nature (1969) 2.22
Conjugal transfer of imipenem resistance in Bacteroides fragilis. J Antibiot (Tokyo) (1992) 2.22
Extracellular accumulation of a new amino acid, O-2-hydroxypropylhomoserine, from 1,2-propanediol by flavobacterium rigense. Appl Environ Microbiol (1978) 2.21
Down-regulation of CD40 and CD80 on B cells in patients with life-threatening systemic lupus erythematosus after successful treatment with rituximab. Rheumatology (Oxford) (2004) 2.19
Th1/Th2 balance of peripheral T helper cells in systemic lupus erythematosus. Arthritis Rheum (1999) 2.18
Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activation. Nat Immunol (2001) 2.18
The TINS Lecture. The parietal association cortex in depth perception and visual control of hand action. Trends Neurosci (1997) 2.18
Pathophysiology of "tethered cord syndrome". J Neurosurg (1981) 2.17
Identification of the gene loci that predispose to rheumatoid arthritis. Int Immunol (1998) 2.16
Steroid therapy in IgA nephropathy: a retrospective study in heavy proteinuric cases. Nephron (1988) 2.15
Expression and function of OX40 ligand on human dendritic cells. J Immunol (1997) 2.13
The results, indications, and physiology of posteroventral pallidotomy for patients with Parkinson's disease. Neurosurgery (1995) 2.09
Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation. J Clin Invest (1999) 2.09
Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease. Brain (1992) 2.09
The roles of three functional sulphate transporters involved in uptake and translocation of sulphate in Arabidopsis thaliana. Plant J (2000) 2.09
Fukuyama-type congenital muscular dystrophy and the Walker-Warburg syndrome. Brain Dev (1993) 2.08
MUC1 mucin expression as a marker of progression and metastasis of human colorectal carcinoma. Gastroenterology (1994) 2.08
Genetic dissection of nodal function in patterning the mouse embryo. Development (2001) 2.07
Structure-function analysis of the Bcl-2 oncoprotein. Addition of a heterologous transmembrane domain to portions of the Bcl-2 beta protein restores function as a regulator of cell survival. J Biol Chem (1993) 2.07
Reaction of sevoflurane and its degradation products with soda lime. Toxicity of the byproducts. Anesthesiology (1992) 2.07
Classification and Structural Comparison of Full-Length cDNAs for Pathogenesis-Related Proteins. Plant Physiol (1987) 2.06
Discontinuation of infliximab after attaining low disease activity in patients with rheumatoid arthritis: RRR (remission induction by Remicade in RA) study. Ann Rheum Dis (2010) 2.04
Right-handed rotation of an actin filament in an in vitro motile system. Nature (1993) 2.04
The Dictyostelium developmental cDNA project: generation and analysis of expressed sequence tags from the first-finger stage of development. DNA Res (1998) 2.03
Postmarketing surveillance of the safety profile of infliximab in 5000 Japanese patients with rheumatoid arthritis. Ann Rheum Dis (2007) 2.01
Synthesis and antibacterial activities of substituted 7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxyl ic acids. Chem Pharm Bull (Tokyo) (1984) 1.99
Chronic active and lupoid hepatitis caused by a laxative, oxyphenisatin. N Engl J Med (1971) 1.98
Activation of mitogen-activated protein kinases/extracellular signal-regulated kinases in human hepatocellular carcinoma. Hepatology (1998) 1.97
Molecular cloning and characterization of a novel human gene (HERNA) which encodes a putative RNA-helicase. Biochim Biophys Acta (2000) 1.97
Hepatitis B virus genotype assignment using restriction fragment length polymorphism patterns. FEBS Lett (1999) 1.96
The expression of Ia antigens on immunocompetent cells in the guinea pig. II. Ia antigens on macrophages. J Immunol (1977) 1.96