Published in Proc Natl Acad Sci U S A on January 01, 1975
Changes in the conformation of influenza virus hemagglutinin at the pH optimum of virus-mediated membrane fusion. Proc Natl Acad Sci U S A (1982) 7.34
N- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple-stranded coiled coil. Proc Natl Acad Sci U S A (1999) 3.90
Purification of the fusion protein of Sendai virus: analysis of the NH2-terminal sequence generated during precursor activation. Proc Natl Acad Sci U S A (1978) 3.42
Membrane fusion activity of influenza virus. EMBO J (1982) 2.97
The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor. EMBO J (1984) 2.77
Rat brain Thy-1 glycoprotein. The amino acid sequence, disulphide bonds and an unusual hydrophobic region. Biochem J (1981) 2.63
Mutations in the cytoplasmic domain of the influenza virus hemagglutinin affect different stages of intracellular transport. J Cell Biol (1985) 2.60
Conservation and variation in the hemagglutinins of Hong Kong subtype influenza viruses during antigenic drift. J Virol (1981) 2.35
A soluble domain of the membrane-anchoring chain of influenza virus hemagglutinin (HA2) folds in Escherichia coli into the low-pH-induced conformation. Proc Natl Acad Sci U S A (1995) 2.24
Expression of Semliki Forest virus proteins from cloned complementary DNA. I. The fusion activity of the spike glycoprotein. J Cell Biol (1983) 2.03
Analysis of progressive deletions of the transmembrane and cytoplasmic domains of influenza hemagglutinin. J Cell Biol (1986) 1.94
Influenza virus site recognized by a murine helper T cell specific for H1 strains. Localization to a nine amino acid sequence in the hemagglutinin molecule. J Exp Med (1983) 1.94
Insertion of influenza M protein into the viral lipid bilayer and localization of site of insertion. J Virol (1981) 1.65
Recognition of viral glycoproteins by influenza A-specific cross-reactive cytolytic T lymphocytes. J Exp Med (1980) 1.58
A serpin shapes the extracellular environment to prevent influenza A virus maturation. Cell (2015) 1.57
Surface structure of Uukuniemi virus. J Virol (1975) 1.49
Proteins of the kidney microvillar membrane. The amphipathic form of dipeptidyl peptidase IV. Biochem J (1979) 1.47
Nucleotide sequence of the 3' half of AKV. Nucleic Acids Res (1982) 1.40
Analysis of the genetic diversity of influenza A viruses using next-generation DNA sequencing. BMC Genomics (2015) 1.38
Interaction of influenza M protein with viral lipid and phosphatidylcholine vesicles. J Virol (1980) 1.34
Chromatographic isolation of the hemagglutinin polypeptides from influenza virus vaccine and determination of their amino-terminal sequences. Proc Natl Acad Sci U S A (1976) 1.33
Carbohydrates of influenza virus. I. Glycopeptides derived from viral glycoproteins after labeling with radioactive sugars. J Virol (1977) 1.33
Effect of the N-terminal glycine on the secondary structure, orientation, and interaction of the influenza hemagglutinin fusion peptide with lipid bilayers. Biophys J (1996) 1.31
A new concept of the epidemic process of influenza A virus. Epidemiol Infect (1987) 1.29
Targeting B cell responses in universal influenza vaccine design. Trends Immunol (2011) 1.27
Studies on influenza haemagglutinin fusion peptide mutants generated by reverse genetics. EMBO J (2001) 1.23
Requirement of N-terminal amino acid residues of gp41 for human immunodeficiency virus type 1-mediated cell fusion. J Virol (1995) 1.20
Radioimmunoprecipitation assay for quantitation of serum antibody to the hemagglutinin of type A influenza virus. J Clin Microbiol (1978) 1.17
Cleavage of influenza a virus hemagglutinin in human respiratory epithelium is cell associated and sensitive to exogenous antiproteases. J Virol (2002) 1.14
Amino-terminal sequence analysis of the structural proteins of Sindbis virus. Proc Natl Acad Sci U S A (1978) 1.13
Genomewide analysis of reassortment and evolution of human influenza A(H3N2) viruses circulating between 1968 and 2011. J Virol (2013) 1.13
The structure of a membrane fusion mutant of the influenza virus haemagglutinin. EMBO J (1990) 1.11
Immunogenicity of influenza virus vaccine is increased by anti-gal-mediated targeting to antigen-presenting cells. J Virol (2007) 1.09
Universal influenza B vaccine based on the maturational cleavage site of the hemagglutinin precursor. J Virol (2005) 1.07
An efficient method for introducing defined lipids into the plasma membrane of mammalian cells. J Cell Biol (1983) 1.05
Drastic immunoreactivity changes between the immature and mature forms of the Sendai virus HN and F0 glycoproteins. J Virol (1986) 1.04
Cellular changes in lungs of mice infected with influenza virus: characterization of the cytotoxic responses. Infect Immun (1978) 1.01
Glycosylation sites of influenza viral glycoproteins: characterization of tryptic glycopeptides from the A/USSR(H1N1) hemagglutinin glycoprotein. J Virol (1981) 1.01
Lymphocyte blastogenic responses to influenza virus antigens after influenza infection and vaccination in humans. Infect Immun (1978) 1.01
Pandemic influenza vaccine: characterization of A/California/07/2009 (H1N1) recombinant hemagglutinin protein and insights into H1N1 antigen stability. BMC Biotechnol (2012) 0.91
A single residue substitution in the receptor-binding domain of H5N1 hemagglutinin is critical for packaging into pseudotyped lentiviral particles. PLoS One (2012) 0.89
Role of hemagglutinin cleavage and expression of M1 protein in replication of A/WS/33, A/PR/8/34, and WSN influenza viruses in mouse brain. J Virol (1989) 0.89
Recent contributions of molecular biology to the clinical virology of myxoviruses. Yale J Biol Med (1980) 0.85
Rapid and specific influenza virus detection by functionalized magnetic nanoparticles and mass spectrometry. J Nanobiotechnology (2011) 0.82
Delivery of nucleic acids and nanomaterials by cell-penetrating peptides: opportunities and challenges. Biomed Res Int (2015) 0.80
Tamiflu-resistant but HA-mediated cell-to-cell transmission through apical membranes of cell-associated influenza viruses. PLoS One (2011) 0.79
Role of cellular proteases in viral pathogenicity. Trans Am Clin Climatol Assoc (1979) 0.79
Nasal commensal Staphylococcus epidermidis counteracts influenza virus. Sci Rep (2016) 0.78
Approaches towards rational antiviral chemotherapy. Postgrad Med J (1979) 0.77
The molecular mechanism of action of the CR6261-Azichromycin combination found through computational analysis. PLoS One (2012) 0.77
Utilization of Glycosaminoglycans/Proteoglycans as Carriers for Targeted Therapy Delivery. Int J Cell Biol (2015) 0.76
Membrane proteins and virus virulence. Trans Am Clin Climatol Assoc (1984) 0.76
Effects of bacterial microflora of the lower digestive tract of free-range waterfowl on influenza virus activation. Appl Environ Microbiol (2011) 0.75
Functional chimeras of human immunodeficiency virus type 1 Gp120 and influenza A virus (H3) hemagglutinin. J Virol (2005) 0.75
Cleavage site and Ectodomain of HA2 sub-unit sequence of three equine influenza virus isolated in Morocco. BMC Res Notes (2014) 0.75
Molecular weight estimation of polypeptide chains by electrophoresis in SDS-polyacrylamide gels. Biochem Biophys Res Commun (1967) 32.60
A protein sequenator. Eur J Biochem (1967) 17.03
Sequence of a repressor-binding site in the DNA of bacteriophage lamda. Nature (1974) 6.22
Quantitative procedures for use with the Edman-Begg sequenator. Partial sequences of two unusual immunoglobulin light chains, Rzf and Sac. Biochemistry (1971) 6.10
Crystalline antigen from the influenza virus envelope. Nat New Biol (1972) 5.77
Influenza virus structural and nonstructural proteins in infected cells and their plasma membranes. Virology (1971) 3.96
The polypeptide composition of influenza A viruses. Virology (1971) 3.79
STRUCTURAL STUDIES ON THE PROTEIN SUBUNITS FROM THREE STRAINS OF INFLUENZA VIRUS. J Mol Biol (1964) 3.77
Studies on the formation of the influenza virus envelope. Virology (1974) 3.39
Palindromes in chromosomes. J Mol Biol (1974) 3.02
Inhibition of glycoprotein biosynthesis of influenza virus by D-glucosamine and 2-deoxy-D-glucose. Virology (1972) 2.84
Polypeptide synthesis in influenza virus-infected cells. Virology (1972) 2.70
Advances in the gas chromatographic analysis of amino acid phenyl- and methylthiohydantoins. Anal Biochem (1972) 2.56
The sequence of amino acid residues in bovine pancreatic ribonuclease: revisions and confirmations. J Biol Chem (1963) 2.49
Separation of two polypeptide chains from the hemagglutinin subunit of influenza virus. Virology (1971) 2.07
Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution. Nature (1981) 24.17
Atomic structure of the ectodomain from HIV-1 gp41. Nature (1997) 16.31
Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation. Nature (1981) 15.85
Structure of influenza haemagglutinin at the pH of membrane fusion. Nature (1994) 14.61
Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences. Nature (1984) 14.21
The structure and function of the hemagglutinin membrane glycoprotein of influenza virus. Annu Rev Biochem (1987) 11.99
Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature (1994) 10.34
Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus. Nature (1983) 8.60
Synthesis and function of 3-phosphorylated inositol lipids. Annu Rev Biochem (2001) 8.47
Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid. Nature (1988) 8.32
Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity. Nature (1983) 8.28
Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin. Nature (1985) 8.23
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science (1993) 7.86
The structure and receptor binding properties of the 1918 influenza hemagglutinin. Science (2004) 7.74
Changes in the conformation of influenza virus hemagglutinin at the pH optimum of virus-mediated membrane fusion. Proc Natl Acad Sci U S A (1982) 7.34
The molecular basis of the specific anti-influenza action of amantadine. EMBO J (1985) 7.08
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras. Cell (1997) 6.55
Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways. Science (1986) 6.10
X-ray structures of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs. Proc Natl Acad Sci U S A (2001) 5.92
Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer. Annu Rev Cell Dev Biol (2001) 5.80
Crystalline antigen from the influenza virus envelope. Nat New Biol (1972) 5.77
Autophosphorylation sites on the epidermal growth factor receptor. Nature (1984) 5.11
Fusion mutants of the influenza virus hemagglutinin glycoprotein. Cell (1985) 4.84
Nucleotide sequences at the 5' termini of influenza virus RNAs and their transcripts. Nucleic Acids Res (1978) 4.83
Signaling by distinct classes of phosphoinositide 3-kinases. Exp Cell Res (1999) 4.79
Phosphatidylinositol-3-OH kinases are Rab5 effectors. Nat Cell Biol (1999) 4.76
Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain. Mol Cell (1998) 4.73
Phosphoinositide 3-kinases: a conserved family of signal transducers. Trends Biochem Sci (1997) 4.52
A carbohydrate side chain on hemagglutinins of Hong Kong influenza viruses inhibits recognition by a monoclonal antibody. Proc Natl Acad Sci U S A (1984) 4.37
Cytotoxic T cells to type A influenza virus; viral hemagglutinin induces A-strain specificity while infected cells confer cross-reactive cytotoxicity. Eur J Immunol (1977) 4.05
Antibodies against a synthetic peptide as a probe for the kinase activity of the avian EGF receptor and v-erbB protein. Cell (1985) 4.02
The complete primary structure of protein kinase C--the major phorbol ester receptor. Science (1986) 4.02
Transcription of the influenza virus genome. Virology (1977) 4.02
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation. EMBO J (1996) 3.99
N- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple-stranded coiled coil. Proc Natl Acad Sci U S A (1999) 3.90
The polypeptide composition of influenza A viruses. Virology (1971) 3.79
Studies on the in vitro transcription of reovirus RNA catalyzed by reovirus cores. Virology (1969) 3.79
The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth. EMBO J (1996) 3.78
Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements. Nat Struct Biol (1999) 3.72
Structure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformation. Cell (1998) 3.69
Cytotoxic T cells kill influenza virus infected cells but do not distinguish between serologically distinct type A viruses. Nature (1977) 3.67
Signalling through phosphoinositide 3-kinases: the lipids take centre stage. Curr Opin Cell Biol (1999) 3.47
Analyses of the antigenicity of influenza haemagglutinin at the pH optimum for virus-mediated membrane fusion. J Gen Virol (1983) 3.43
Purification of the fusion protein of Sendai virus: analysis of the NH2-terminal sequence generated during precursor activation. Proc Natl Acad Sci U S A (1978) 3.42
Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase. EMBO J (1996) 3.41
Structural basis for membrane fusion by enveloped viruses. Mol Membr Biol (1999) 3.26
A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system. EMBO J (1995) 3.19
P110delta, a novel phosphoinositide 3-kinase in leukocytes. Proc Natl Acad Sci U S A (1997) 3.09
Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction. Mol Cell Biol (1996) 3.08
A monoclonal antibody to the human epidermal growth factor receptor. J Cell Biochem (1982) 3.04
The receptor-binding and membrane-fusion properties of influenza virus variants selected using anti-haemagglutinin monoclonal antibodies. EMBO J (1987) 3.03
Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography. Biochemistry (1992) 3.03
PI 3-kinase: structural and functional analysis of intersubunit interactions. EMBO J (1994) 3.02
Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis. Proc Natl Acad Sci U S A (1985) 3.01
Large and small tumor antigens from simian virus 40 have identical amino termini mapping at 0.65 map units. Proc Natl Acad Sci U S A (1978) 3.00
Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type-2 astrocyte progenitor cell. Nature (1988) 2.99
The influenza A virus nucleoprotein gene controls the induction of both subtype specific and cross-reactive cytotoxic T cells. J Exp Med (1984) 2.81
Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor. Curr Biol (1999) 2.76
Studies with crosslinking reagents on the oligomeric structure of the env glycoprotein of HIV. Virology (1989) 2.74
Polypeptide synthesis in influenza virus-infected cells. Virology (1972) 2.70
H1 and H7 influenza haemagglutinin structures extend a structural classification of haemagglutinin subtypes. Virology (2004) 2.67
Antigenic similarity of influenza A (H1N1) viruses from epidemics in 1977--1978 to "Scandinavian" strains isolated in epidemics of 1950--1951. Virology (1978) 2.61
Refinement of the influenza virus hemagglutinin by simulated annealing. J Mol Biol (1990) 2.61
An antibody that prevents the hemagglutinin low pH fusogenic transition. Virology (2002) 2.56
Structure of influenza virus haemagglutinin complexed with a neutralizing antibody. Nature (1995) 2.55
Binding of the influenza A virus to cell-surface receptors: structures of five hemagglutinin-sialyloligosaccharide complexes determined by X-ray crystallography. Virology (1997) 2.51
On the mechanism of inhibition of influenza virus replication by amantadine hydrochloride. J Gen Virol (1978) 2.50
Interferon action--sequence specificity of the ppp(A2'p)nA-dependent ribonuclease. Nature (1981) 2.49
Introduction of intersubunit disulfide bonds in the membrane-distal region of the influenza hemagglutinin abolishes membrane fusion activity. Cell (1992) 2.47
A complex of influenza hemagglutinin with a neutralizing antibody that binds outside the virus receptor binding site. Nat Struct Biol (1999) 2.47
The polypeptides of adenovirus-infected cells. J Gen Virol (1972) 2.43
Expression of a platelet-derived growth factor-like protein in simian sarcoma virus transformed cells. Science (1983) 2.41
Structure of the haemagglutinin-esterase-fusion glycoprotein of influenza C virus. Nature (1998) 2.41
Expression of epidermal growth factor receptors on human cervical, ovarian, and vulval carcinomas. Cancer Res (1986) 2.38
Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading. Cancer Res (1988) 2.36
Characterization of influenza virus RNA complete transcripts. Virology (1982) 2.31
Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3'-kinase SH2 domains: a model for SH2-mediated receptor-target interactions. EMBO J (1992) 2.29
Expression of the c-erbB-2 protein in normal and transformed cells. Int J Cancer (1987) 2.27
Influenza virus messenger RNAs are incomplete transcripts of the genome RNAs. Nucleic Acids Res (1977) 2.26
A soluble domain of the membrane-anchoring chain of influenza virus hemagglutinin (HA2) folds in Escherichia coli into the low-pH-induced conformation. Proc Natl Acad Sci U S A (1995) 2.24
Hemagglutinins from two influenza virus variants bind to sialic acid derivatives with millimolar dissociation constants: a 500-MHz proton nuclear magnetic resonance study. Biochemistry (1989) 2.24
Autophosphorylation and protein kinase C phosphorylation of the epidermal growth factor receptor. Effect on tyrosine kinase activity and ligand binding affinity. J Biol Chem (1985) 2.22
The ectodomain of HIV-1 env subunit gp41 forms a soluble, alpha-helical, rod-like oligomer in the absence of gp120 and the N-terminal fusion peptide. EMBO J (1996) 2.21
Studies on the structure of the influenza virus haemagglutinin at the pH of membrane fusion. J Gen Virol (1988) 2.21
Solution structure and ligand-binding site of the SH3 domain of the p85 alpha subunit of phosphatidylinositol 3-kinase. Cell (1993) 2.20
Virus replication in enucleate cells: vesicular stomatitis virus and influenza virus. J Virol (1974) 2.19
Conformational changes in the hemagglutinin of influenza virus which accompany heat-induced fusion of virus with liposomes. Virology (1986) 2.13
Purification and properties of porcine platelet-derived growth factor. EMBO J (1984) 2.06
Purification and characterization of vaccinia virus growth factor. Cell (1985) 2.06
Activated phosphoinositide 3-kinase associates with membrane skeleton in thrombin-exposed platelets. J Biol Chem (1992) 2.04
Molecular basis of resistance of influenza A viruses to amantadine. J Antimicrob Chemother (1986) 2.04
Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion. Proc Natl Acad Sci U S A (2001) 2.04
Structural evidence for recognition of a single epitope by two distinct antibodies. Proteins (2000) 1.99
Studies on the adaptation of influenza viruses to MDCK cells. EMBO J (1984) 1.98
Purification to homogeneity of protein kinase C from bovine brain--identity with the phorbol ester receptor. EMBO J (1984) 1.97
Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages. Nat Cell Biol (1999) 1.96
Studies of the membrane fusion activities of fusion peptide mutants of influenza virus hemagglutinin. J Virol (1995) 1.96
Studies of the binding properties of influenza hemagglutinin receptor-site mutants. Virology (1998) 1.95
Evidence from studies with a cross-linking reagent that the haemagglutinin of influenza virus is a trimer. Virology (1977) 1.93