Published in Mol Microbiol on November 01, 1999
p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activity. Mol Cell Biol (2008) 1.20
A glucosinolate mutant of Arabidopsis is thermosensitive and defective in cytosolic Hsp90 expression after heat stress. Plant Physiol (2000) 1.02
ATP binding to Hsp90 is sufficient for effective chaperoning of p53 protein. J Biol Chem (2010) 0.89
Plant Hsp90 proteins interact with B-cells and stimulate their proliferation. PLoS One (2011) 0.76
The heat-shock response. Annu Rev Biochem (1986) 20.16
Hsp90 as a capacitor for morphological evolution. Nature (1998) 13.60
The Complex Carbohydrate Structure Database. Trends Biochem Sci (1989) 9.00
The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome. Cell (1989) 8.93
A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1. Antimicrob Agents Chemother (2000) 8.54
Oral lesions in sheep and cattle in Dumfries and Galloway. Vet Rec (2001) 7.78
Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins. Cell (1998) 7.69
The function of heat-shock proteins in stress tolerance: degradation and reactivation of damaged proteins. Annu Rev Genet (1993) 7.60
Support for the prion hypothesis for inheritance of a phenotypic trait in yeast. Science (1996) 7.24
Protein disaggregation mediated by heat-shock protein Hsp104. Nature (1994) 6.27
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature (2000) 5.86
Altered fidelity of mitotic chromosome transmission in cell cycle mutants of S. cerevisiae. Genetics (1985) 5.75
Small heat shock proteins are molecular chaperones. J Biol Chem (1993) 5.62
hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures. Mol Cell Biol (1989) 5.37
Self-seeded fibers formed by Sup35, the protein determinant of [PSI+], a heritable prion-like factor of S. cerevisiae. Cell (1997) 5.24
Reduced levels of hsp90 compromise steroid receptor action in vivo. Nature (1990) 5.23
Human lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal localization. Nucleic Acids Res (1985) 5.22
The extent of Down's syndrome screening in Britain in 1991. Lancet (1992) 5.20
Maternal serum screening for Down's syndrome: the effect of routine ultrasound scan determination of gestational age and adjustment for maternal weight. Br J Obstet Gynaecol (1992) 5.11
Control of acid resistance in Escherichia coli. J Bacteriol (1999) 4.93
Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus. Nature (1986) 4.70
Rnq1: an epigenetic modifier of protein function in yeast. Mol Cell (2000) 4.62
The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels. Cell (1982) 4.62
A good practice guide to the administration of substances and removal of blood, including routes and volumes. J Appl Toxicol (2001) 4.39
Single-molecule studies of DNA mechanics. Curr Opin Struct Biol (2000) 4.39
Regulation of protein synthesis during heat shock. Nature (1981) 4.38
HSP100/Clp proteins: a common mechanism explains diverse functions. Trends Biochem Sci (1996) 4.27
Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. J Clin Invest (1987) 4.26
Analysis of yeast protein kinases using protein chips. Nat Genet (2000) 3.94
Role of the protein chaperone YDJ1 in establishing Hsp90-mediated signal transduction pathways. Science (1995) 3.91
Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins. Proc Natl Acad Sci U S A (2000) 3.82
Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase. Mol Cell Biol (1995) 3.79
Classification, nomenclature, and database development for hepatitis C virus (HCV) and related viruses: proposals for standardization. International Committee on Virus Taxonomy. Arch Virol (1998) 3.77
Hsp104 is required for tolerance to many forms of stress. EMBO J (1992) 3.72
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation. Cell (1999) 3.58
RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis. Cell (1986) 3.53
Bone lead as a biological marker in epidemiologic studies of chronic toxicity: conceptual paradigms. Environ Health Perspect (1998) 3.51
Assessment of commercial laboratories performing hair mineral analysis. JAMA (2001) 3.42
Hsp26 is not required for growth at high temperatures, nor for thermotolerance, spore development, or germination. Cell (1986) 3.39
Varying patterns of protein synthesis in Drosophila during heat shock: implications for regulation. Dev Biol (1980) 3.35
Multiple effects of trehalose on protein folding in vitro and in vivo. Mol Cell (1998) 3.33
hsp70: nuclear concentration during environmental stress and cytoplasmic storage during recovery. Cell (1984) 3.30
Heat shock protein 101 plays a crucial role in thermotolerance in Arabidopsis. Plant Cell (2000) 3.30
Hsp70 and Hsp90--a relay team for protein folding. Rev Physiol Biochem Pharmacol (2004) 3.29
The preferential translation of Drosophila hsp70 mRNA requires sequences in the untranslated leader. Cell (1985) 3.25
Intracellular localization of heat shock proteins in Drosophila. Cell (1980) 3.24
Hsp90 chaperones protein folding in vitro. Nature (1992) 3.19
Hsp90: chaperoning signal transduction. J Cell Physiol (2001) 3.13
Temperate Bacteriophage Which Causes the Production of a New Major Outer Membrane Protein by Escherichia coli. J Virol (1975) 3.11
The consequences of expressing hsp70 in Drosophila cells at normal temperatures. Genes Dev (1992) 3.00
Assisting spontaneity: the role of Hsp90 and small Hsps as molecular chaperones. Trends Biochem Sci (1994) 2.99
Inactivation of the ampD gene causes semiconstitutive overproduction of the inducible Citrobacter freundii beta-lactamase. J Bacteriol (1987) 2.95
Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation. EMBO J (1997) 2.92
Heat-shock protein hsp90 governs the activity of pp60v-src kinase. Proc Natl Acad Sci U S A (1993) 2.92
Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation. J Biol Chem (1999) 2.85
Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science (1998) 2.83
Hsp104 is a highly conserved protein with two essential nucleotide-binding sites. Nature (1991) 2.81
Creating a protein-based element of inheritance. Science (2000) 2.76
The spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins. Mol Biol Cell (1999) 2.75
Retrohoming of a bacterial group II intron: mobility via complete reverse splicing, independent of homologous DNA recombination. Cell (1998) 2.74
AIDS and self-organization among intravenous drug users. Int J Addict (1987) 2.73
In vivo functions of the Saccharomyces cerevisiae Hsp90 chaperone. Proc Natl Acad Sci U S A (1997) 2.71
Chaperone function of Hsp90-associated proteins. Science (1996) 2.66
The National Health Service needs a voice of its own. J R Soc Med (2000) 2.65
Accreditation in transoesophageal echocardiography: statement from the Association of Cardiothoracic Anaesthetists and the British Society of Echocardiography Joint TOE Accreditation Committee. Br J Anaesth (2003) 2.64
A functional mitotic spindle prepared from mammalian cells in culture. Proc Natl Acad Sci U S A (1974) 2.64
Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2000) 2.63
An ancient developmental induction: heat-shock proteins induced in sporulation and oogenesis. Science (1986) 2.60
Hsp26: a temperature-regulated chaperone. EMBO J (1999) 2.51
Retrotransposition of a bacterial group II intron. Nature (2000) 2.51
Psychological interventions to improve adherence to oral hygiene instructions in adults with periodontal diseases. Cochrane Database Syst Rev (2007) 2.47
Oligopeptide-repeat expansions modulate 'protein-only' inheritance in yeast. Nature (1999) 2.43
Transient interaction of Hsp90 with early unfolding intermediates of citrate synthase. Implications for heat shock in vivo. J Biol Chem (1995) 2.42
Additional educational needs in children born to mothers with epilepsy. J Neurol Neurosurg Psychiatry (2001) 2.40
Serum screening for Down's syndrome between 8 and 14 weeks of pregnancy. International Prenatal Screening Research Group. Br J Obstet Gynaecol (1996) 2.40
Treatment of advanced breast cancer with sterically stabilized liposomal doxorubicin: results of a multicenter phase II trial. J Clin Oncol (1997) 2.39
Prognostic indicators for AIDS and infectious disease death in HIV-infected injection drug users: plasma viral load and CD4+ cell count. JAMA (1998) 2.37
A nested-PCR-based schizodeme method for identifying Leishmania kinetoplast minicircle classes directly from clinical samples and its application to the study of the epidemiology of Leishmania tropica in Pakistan. J Clin Microbiol (1998) 2.35
Amino acid sequence of the alpha subunit of transducin deduced from the cDNA sequence. Proc Natl Acad Sci U S A (1985) 2.34
Patterns of differentiation and hybridization in North American wolflike canids, revealed by analysis of microsatellite loci. Mol Biol Evol (1994) 2.28
Hormone receptors: studies on the interaction of estrogen with the uterus. Recent Prog Horm Res (1968) 2.28
A cyclophilin function in Hsp90-dependent signal transduction. Science (1996) 2.28
The role of Sis1 in the maintenance of the [RNQ+] prion. EMBO J (2001) 2.26
The small heat-shock protein IbpB from Escherichia coli stabilizes stress-denatured proteins for subsequent refolding by a multichaperone network. J Biol Chem (1998) 2.23
Identification of Harper-Cawston factor as thymidine phosphorylase and removal from media of substances interfering with susceptibility testing to sulfonamides and diaminopyrimidines. Antimicrob Agents Chemother (1975) 2.22
GDNF signalling through the Ret receptor tyrosine kinase. Nature (1996) 2.21
The natural history of treated and untreated primary hyperparathyroidism: the parathyroid epidemiology and audit research study. QJM (2011) 2.20
Severe adverse life events and depressive symptoms among women with, or at risk for, HIV infection in four cities in the United States of America. AIDS (1999) 2.20
In vivo analysis of the Hsp90 cochaperone Sti1 (p60). Mol Cell Biol (1997) 2.17
Randomized phase II study of two gemcitabine schedules for patients with impaired performance status (Karnofsky performance status </= 70) and advanced non-small-cell lung cancer. J Clin Oncol (2005) 2.17
An association between type 1 diabetes and idiopathic generalized epilepsy. Ann Neurol (2006) 2.15
Is the major Drosophila heat shock protein present in cells that have not been heat shocked? J Cell Biol (1983) 2.14
Measurement and characterization of postischemic free radical generation in the isolated perfused heart. J Biol Chem (1989) 2.14
Observations in the Haight-Ashbury Medical Clinic of San Francisco. Health problems in a "hippie" subculture. Clin Pediatr (Phila) (1968) 2.12
Thermotolerance in Saccharomyces cerevisiae: the Yin and Yang of trehalose. Trends Biotechnol (1998) 2.11
Ribonuclease P: function and variation. J Biol Chem (1990) 2.07
Changing patterns of gene expression during sporulation in yeast. Proc Natl Acad Sci U S A (1984) 2.06
Biological properties of a CD4 immunoadhesin. Nature (1990) 2.05