Published in Proc Natl Acad Sci U S A on May 01, 1975
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Synthesis of lecithins by acylation of O-(sn-glycero-3-phosphoryl) choline with fatty acid anhydrides. Biochim Biophys Acta (1969) 3.53
Fluorescence and the location of tryptophan residues in protein molecules. Photochem Photobiol (1973) 3.24
The structure of Escherichia coli membranes studied by fluorescence measurements of lipid phase transitions. Biochim Biophys Acta (1973) 2.03
Fluorescent probes of biological membranes. Proc Natl Acad Sci U S A (1970) 1.87
Proximity relationships in rhodopsin. Proc Natl Acad Sci U S A (1972) 1.49
Hydrophobic binding sites in bovine serum albumin and erythrocyte ghost proteins. Study by spin-labelling, paramagnetic fluorescence quenching and chemical modification. Biochim Biophys Acta (1974) 1.09
Amino acid sequence adjoining the lone tryptophan of human serum albumin. A binding site of the protein. Biochemistry (1970) 0.93
An analytic solution to the Förster energy transfer problem in two dimensions. Biophys J (1979) 4.03
Sugar transport. Properties of mutant bacteria defective in proteins of the phosphoenolpyruvate: sugar phosphotransferase system. J Biol Chem (1976) 3.57
Coupling of energy to active transport of amino acids in Escherichia coli. Proc Natl Acad Sci U S A (1972) 3.18
The energetics of bacterial active transport. Annu Rev Biochem (1975) 3.17
Genetic evidence for the role of a bacterial phosphotransferase system in sugar transport. Proc Natl Acad Sci U S A (1967) 3.00
Resolution of a staphylococcal phosphotransferase system into four protein components and its relation to sugar transport. Biochem Biophys Res Commun (1968) 2.96
In vivo evidence for the role of the epsilon subunit as an inhibitor of the proton-translocating ATPase of Escherichia coli. J Bacteriol (1984) 2.60
The physiological behavior of enzyme I and heat-stable protein mutants of a bacterial phosphotransferase system. J Biol Chem (1970) 2.39
Transient increase in phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol trisphosphate during activation of human neutrophils. J Biol Chem (1989) 2.35
Phospholipid lateral phase separation and the partition of cis-parinaric acid and trans-parinaric acid among aqueous, solid lipid, and fluid lipid phases. Biochemistry (1979) 2.35
Signal transduction and cytoskeletal activation in the neutrophil. Physiol Rev (1987) 2.34
Conjugated polyene fatty acids on fluorescent probes: spectroscopic characterization. Biochemistry (1977) 2.19
An inositol tetrakisphosphate-containing phospholipid in activated neutrophils. Nature (1988) 2.07
Impairment and restoration of the energized state in membrane vesicles of a mutant of Escherichia coli lacking adenosine triphosphatase. J Biol Chem (1974) 2.02
Gene order and gene-polypeptide relationships of the proton-translocating ATPase operon (unc) of Escherichia coli. Proc Natl Acad Sci U S A (1982) 1.99
Sugar transport. IV. Isolation and characterization of the lactose phosphotransferase system in Staphylococcus aureus. J Biol Chem (1973) 1.95
Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase. Proc Natl Acad Sci U S A (1986) 1.87
Fat metabolism in higher plants. XXXI. Purification and properties of plant and bacterial acyl carrier proteins. J Biol Chem (1967) 1.87
Sugar transport. VII. Lactose transport in Staphylococcus aureus. J Biol Chem (1973) 1.82
Conjugated polyene fatty acids as fluorescent probes: synthetic phospholipid membrane studies. Biochemistry (1977) 1.81
Genetic and biomedical studies demonstrating a second gene coding for asparagine synthetase in Escherichia coli. J Bacteriol (1980) 1.80
Relationship of actin polymerization and depolymerization to light scattering in human neutrophils: dependence on receptor occupancy and intracellular Ca++. J Cell Biol (1985) 1.76
A quantitative fluorimetric assay for the determination of oxidant production by polymorphonuclear leukocytes: its use in the simultaneous fluorimetric assay of cellular activation processes. Anal Biochem (1984) 1.74
Beta 2-integrin and L-selectin are obligatory receptors in neutrophil aggregation. Blood (1993) 1.74
Cholesterol and vesicular stomatitis virus G protein take separate routes from the endoplasmic reticulum to the plasma membrane. J Biol Chem (1990) 1.73
Is there a relationship between phosphatidylinositol trisphosphate and F-actin polymerization in human neutrophils? J Biol Chem (1990) 1.65
Assembly of a functional F0 of the proton-translocating ATPase of Escherichia coli. J Biol Chem (1983) 1.60
In vitro synthesis of the F0 and F1 components of the proton translocating ATPase of Escherichia coli. J Biol Chem (1981) 1.56
7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome. J Clin Invest (2001) 1.55
Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation. J Biol Chem (2001) 1.51
Priming of polymorphonuclear granulocytes by lipopolysaccharides and its complexes with lipopolysaccharide binding protein and high density lipoprotein. J Leukoc Biol (1990) 1.51
Sugar transport. VI. Phosphoryl transfer in the lactose phosphotransferase system of Staphylococcus aureus. J Biol Chem (1973) 1.49
Transport of cholesterol from the endoplasmic reticulum to the plasma membrane. J Cell Biol (1985) 1.49
Escherichia coli mutants defective in the uncH gene. J Bacteriol (1983) 1.47
L-selectin (CD62L) cross-linking signals neutrophil adhesive functions via the Mac-1 (CD11b/CD18) beta 2-integrin. J Immunol (1995) 1.46
The regulated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase requires a short-lived protein and occurs in the endoplasmic reticulum. J Biol Chem (1990) 1.43
Rap1A is a substrate for cyclic AMP-dependent protein kinase in human neutrophils. J Immunol (1991) 1.43
The emergence of flow cytometry for sensitive, real-time measurements of molecular interactions. Nat Biotechnol (1998) 1.42
P-selectin glycoprotein ligand-1 (PSGL-1) is a ligand for L-selectin in neutrophil aggregation. Blood (1996) 1.40
Biogenesis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, an integral glycoprotein of the endoplasmic reticulum. Proc Natl Acad Sci U S A (1984) 1.40
Functional analysis of point mutations in human flap endonuclease-1 active site. Nucleic Acids Res (1997) 1.39
The dynamics of ligand-receptor interactions. Real-time analyses of association, dissociation, and internalization of an N-formyl peptide and its receptors on the human neutrophil. J Biol Chem (1984) 1.39
Rapid modulation of N-formyl chemotactic peptide receptors on the surface of human granulocytes: formation of high-affinity ligand-receptor complexes in transient association with cytoskeleton. J Cell Biol (1984) 1.39
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Proton translocation by the F1F0ATPase of Escherichia coli. Mutagenic analysis of the a subunit. J Biol Chem (1989) 1.36
Genetic analysis of carbohydrate transport-deficient mutants of Salmonella typhimurium. J Bacteriol (1969) 1.35
Essential amino acids for substrate binding and catalysis of human flap endonuclease 1. J Biol Chem (1996) 1.35
Differential polypeptide synthesis of the proton-translocating ATPase of Escherichia coli. J Bacteriol (1982) 1.34
Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulum. J Cell Biol (1992) 1.33
Human serum albumin. Spectroscopic studies of binding and proximity relationships for fatty acids and bilirubin. J Biol Chem (1979) 1.29
Photophysics of tryptophan in bacteriophage T4 lysozymes. Biochemistry (1990) 1.29
A continuous, spectroscopic analysis of the kinetics of elastase secretion by neutrophils. The dependence of secretion upon receptor occupancy. J Biol Chem (1982) 1.28
Isolation and characterization of cells resistant to ML236B (compactin) with increased levels of 3-hydroxy-3-methylglutaryl coenzyme A reductase. J Biol Chem (1981) 1.27
Cloning and expression of uncI, the first gene of the unc operon of Escherichia coli. J Bacteriol (1983) 1.27
Signal transduction and ligand-receptor dynamics in the human neutrophil. Transient responses and occupancy-response relations at the formyl peptide receptor. J Biol Chem (1985) 1.27
Degradation of 3-hydroxy-3-methylglutaryl-CoA reductase in endoplasmic reticulum membranes is accelerated as a result of increased susceptibility to proteolysis. J Biol Chem (1996) 1.26
A theory of the effects of head-group structure and chain unsaturation on the chain melting transition of phospholipid dispersions. Biochemistry (1980) 1.25
Neutrophil aggregation is beta 2-integrin- and L-selectin-dependent in blood and isolated cells. J Immunol (1992) 1.24
Intracellular transport of phosphatidylcholine to the plasma membrane. J Cell Biol (1985) 1.22
Performance of in-line microfluidic mixers in laminar flow for high-throughput flow cytometry. Biotechniques (2002) 1.21
In vivo inhibition of cyclin B degradation and induction of cell-cycle arrest in mammalian cells by the neutral cysteine protease inhibitor N-acetylleucylleucylnorleucinal. Proc Natl Acad Sci U S A (1993) 1.21
The membrane domain of 3-hydroxy-3-methylglutaryl-coenzyme A reductase confers endoplasmic reticulum localization and sterol-regulated degradation onto beta-galactosidase. J Biol Chem (1988) 1.20
Energy transduction in Escherichia coli. Genetic alteration of a membrane polypeptide of the (Ca2+,Mg2+)-ATPase. J Biol Chem (1975) 1.20
Interaction between Glu-219 and His-245 within the a subunit of F1F0-ATPase in Escherichia coli. J Biol Chem (1988) 1.18
Oscillating actin polymerization/depolymerization responses in human polymorphonuclear leukocytes. J Biol Chem (1989) 1.18
Intracellular localization of N-formyl chemotactic receptor and Mg2+ dependent ATPase in human granulocytes. Biochim Biophys Acta (1982) 1.18
Promoter for the unc operon of Escherichia coli. J Bacteriol (1983) 1.18
Flow cytometric analysis and modeling of cell-cell adhesive interactions: the neutrophil as a model. J Cell Biol (1990) 1.17
Conjugated polyene fatty acids as fluorescent probes: binding to bovine serum albumin. Biochemistry (1977) 1.17
Intracellular transport of cholesterol to the plasma membrane. J Biol Chem (1982) 1.17
Cytoskeletal and morphologic impact of cellular oxidant injury. Am J Pathol (1986) 1.17
Membrane-cytoskeleton interactions and the regulation of chemotactic peptide-induced activation of human granulocytes: the effects of dihydrocytochalasin B. J Cell Biochem (1985) 1.16
The Fo subunits of the Escherichia coli F1Fo-ATP synthase are sufficient to form a functional proton pore. J Biol Chem (1985) 1.15
Fluorescence lifetime and time-resolved polarization anisotropy studies of acyl chain order and dynamics in lipid bilayers. Biochemistry (1981) 1.15
Mastoparan interacts with the carboxyl terminus of the alpha subunit of Gi. J Biol Chem (1990) 1.14
Inhibition of degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo by cysteine protease inhibitors. J Biol Chem (1991) 1.14
Impaired proton conductivity resulting from mutations in the a subunit of F1F0 ATPase in Escherichia coli. J Biol Chem (1986) 1.14
A topological analysis of subunit alpha from Escherichia coli F1F0-ATP synthase predicts eight transmembrane segments. J Biol Chem (1990) 1.13
The kinetics of neutrophil activation. The response to chemotactic peptides depends upon whether ligand-receptor interaction is rate-limiting. J Biol Chem (1981) 1.12
Analysis of fluorescence lifetime and quenching of FITC-conjugated antibodies on cells by phase-sensitive flow cytometry. Cytometry (1996) 1.12
Ligand/receptor internalization: a spectroscopic analysis and a comparison of ligand binding, cellular response, and internalization by human neutrophils. J Cell Biochem (1982) 1.11
Heparin enhances the interaction of infective Leishmania donovani promastigotes with mouse peritoneal macrophages. A fluorescence flow cytometric analysis. J Immunol (1992) 1.11
Distinct sterol and nonsterol signals for the regulated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase. J Biol Chem (1992) 1.11
Expression of P-selectin at low site density promotes selective attachment of eosinophils over neutrophils. J Immunol (2000) 1.11
Disaturated and dipolyunsaturated phospholipids in the bovine retinal rod outer segment disk membrane. Biochim Biophys Acta (1979) 1.11
Ligand-receptor dynamics and signal amplification in the neutrophil. Adv Immunol (1986) 1.10
Lactose carrier protein of Escherichia coli. Transport and binding of 2'-(N-dansyl)aminoethyl beta-D-thiogalactopyranoside and p-nitrophenyl alpha-d-galactopyranoside. Biochemistry (1979) 1.09
Fluoresceinated chemotactic peptide and high-affinity antifluorescein antibody as a probe of the temporal characteristics of neutrophil stimulation. Proc Natl Acad Sci U S A (1981) 1.08
Nucleotide sequence of the unc operon of Vibrio alginolyticus. Nucleic Acids Res (1989) 1.07
Ribosome-binding sites and RNA-processing sites in the transcript of the Escherichia coli unc operon. J Bacteriol (1989) 1.07
Peptide transport by the multidrug resistance pump. J Biol Chem (1992) 1.06
Hydroxamate-based metalloprotease inhibitor blocks shedding of L-selectin adhesion molecule from leukocytes: functional consequences for neutrophil aggregation. J Immunol (1996) 1.06
Sulfhydryl regulation of L-selectin shedding: phenylarsine oxide promotes activation-independent L-selectin shedding from leukocytes. J Immunol (2000) 1.05