Activation of a cAMP pathway and induction of melanogenesis correlate with association of p16(INK4) and p27(KIP1) to CDKs, loss of E2F-binding activity, and premature senescence of human melanocytes.

PubWeight™: 0.86‹?›

🔗 View Article (PMID 10585280)

Published in Exp Cell Res on December 15, 1999

Authors

M M Haddad1, W Xu, D J Schwahn, F Liao, E E Medrano

Author Affiliations

1: Departments of Cell Biology and Dermatology, Baylor College of Medicine and VAMC, Houston, Texas 77030, USA.

Articles by these authors

A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A (1995) 32.89

Stromal gene signatures in large-B-cell lymphomas. N Engl J Med (2008) 11.34

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci U S A (2001) 11.06

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification. Genes Dev (1998) 7.81

Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection. Nat Med (2000) 7.48

TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature (2000) 6.54

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature (2000) 5.86

Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome. Nature (1997) 3.47

beta-catenin destruction complex: insights and questions from a structural perspective. Oncogene (2006) 3.43

A comparison of clozapine and haloperidol in hospitalized patients with refractory schizophrenia. Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. N Engl J Med (1997) 3.12

Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo. J Exp Med (1995) 2.99

Crystal structure of a beta-catenin/Tcf complex. Cell (2000) 2.93

Prevalence and quantitation of species C adenovirus DNA in human mucosal lymphocytes. J Virol (2002) 2.92

Assembly of a tailed bacterial virus and its genome release studied in three dimensions. Cell (1998) 2.91

A new tick-transmitted disease due to Rickettsia slovaca. Lancet (1997) 2.83

Mice lacking specific nicotinic acetylcholine receptor subunits exhibit dramatically altered spontaneous activity patterns and reveal a limited role for retinal waves in forming ON and OFF circuits in the inner retina. J Neurosci (2000) 2.78

Modulation of abscisic acid signal transduction and biosynthesis by an Sm-like protein in Arabidopsis. Dev Cell (2001) 2.66

Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding. Genes Dev (1999) 2.54

Waist-to-height ratio is the best indicator for undiagnosed type 2 diabetes. Diabet Med (2013) 2.31

A new SIV co-receptor, STRL33. Nature (1997) 2.23

Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides. Nat Med (1998) 2.20

Cytomegalovirus DNA detection in sera from patients with active cytomegalovirus infections. J Clin Microbiol (1992) 2.14

Alkaline response genes of Saccharomyces cerevisiae and their relationship to the RIM101 pathway. J Biol Chem (2000) 2.12

Higher blood flow and circulating NO products offset high-altitude hypoxia among Tibetans. Proc Natl Acad Sci U S A (2007) 2.07

Gene expression and production of the monokine induced by IFN-gamma (MIG), IFN-inducible T cell alpha chemoattractant (I-TAC), and IFN-gamma-inducible protein-10 (IP-10) chemokines by human neutrophils. J Immunol (1999) 2.06

HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature (2001) 2.06

Predicting complicated Crohn's disease and surgery: phenotypes, genetics, serology and psychological characteristics of a population-based cohort. Aliment Pharmacol Ther (2013) 2.05

Monoclonal antibodies directed to different regions of vascular endothelial cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability. Blood (2001) 2.00

Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes. Exp Gerontol (2000) 2.00

Three-dimensional Anderson localization in variable scale disorder. Phys Rev Lett (2013) 1.99

Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice. J Neurochem (2002) 1.96

Physical activity and incidence of coronary heart disease in middle-aged women and men. Med Sci Sports Exerc (1997) 1.94

Restriction point control of cell growth by a labile protein: evidence for increased stability in transformed cells. Proc Natl Acad Sci U S A (1982) 1.93

A single amino acid change in the hemagglutinin protein of measles virus determines its ability to bind CD46 and reveals another receptor on marmoset B cells. J Virol (1998) 1.88

Molecularly cloned SHIV-1157ipd3N4: a highly replication- competent, mucosally transmissible R5 simian-human immunodeficiency virus encoding HIV clade C Env. J Virol (2006) 1.87

A prospective study of coronary heart disease in relation to fasting insulin, glucose, and diabetes. The Atherosclerosis Risk in Communities (ARIC) Study. Diabetes Care (1997) 1.82

Translational control by cytoplasmic polyadenylation of c-mos mRNA is necessary for oocyte maturation in the mouse. EMBO J (1994) 1.80

Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling. J Immunol (1999) 1.78

Regulation of the phage phi 29 prohead shape and size by the portal vertex. Virology (1991) 1.70

Pathways database system: an integrated system for biological pathways. Bioinformatics (2003) 1.67

Evidence for a cluster of genes on chromosome 17q11-q21 controlling susceptibility to tuberculosis and leprosy in Brazilians. Genes Immun (2004) 1.65

Mig, the monokine induced by interferon-gamma, promotes tumor necrosis in vivo. Blood (1997) 1.63

Inhibition of HIV replication by dominant negative mutants of Sam68, a functional homolog of HIV-1 Rev. Nat Med (1999) 1.60

Genome scan for human obesity and linkage to markers in 20q13. Am J Hum Genet (1999) 1.58

Beta-adrenergic receptor subtypes differentially affect apoptosis in adult rat ventricular myocytes. Circulation (2000) 1.53

Is there a genetic basis for lung cancer susceptibility? Recent Results Cancer Res (1999) 1.53

Regulation of microphthalmia-associated transcription factor MITF protein levels by association with the ubiquitin-conjugating enzyme hUBC9. Exp Cell Res (2000) 1.53

A knock-in mouse model reveals roles for nuclear Apc in cell proliferation, Wnt signal inhibition and tumor suppression. Oncogene (2011) 1.49

Tumor cell responses to IFNgamma affect tumorigenicity and response to IL-12 therapy and antiangiogenesis. Immunity (1998) 1.49

Interactions between NADPH oxidase-related proton and electron currents in human eosinophils. J Physiol (2001) 1.46

Proposal for genetic characterisation of wild-type mumps strains: preliminary standardisation of the nomenclature. Arch Virol (2005) 1.45

Anatomy of vasculature of 850 spleen specimens and its application in partial splenectomy. Surgery (1996) 1.45

ADAM 12, a disintegrin metalloprotease, interacts with insulin-like growth factor-binding protein-3. J Biol Chem (2000) 1.45

Hyaluronan fragments synergize with interferon-gamma to induce the C-X-C chemokines mig and interferon-inducible protein-10 in mouse macrophages. J Biol Chem (1998) 1.43

Increased expression of TGF-beta receptors by scleroderma fibroblasts: evidence for contribution of autocrine TGF-beta signaling to scleroderma phenotype. J Invest Dermatol (1998) 1.40

Prevalent deficiency in tumor cells of cycloheximide-induced cycle arrest. Proc Natl Acad Sci U S A (1980) 1.40

Peptide and protein phosphorylation by protein tyrosine kinase Csk: insights into specificity and mechanism. Biochemistry (1998) 1.39

Observation of an antimatter hypernucleus. Science (2010) 1.38

Tcf4 can specifically recognize beta-catenin using alternative conformations. Nat Struct Biol (2001) 1.35

Inducible nitric oxide synthase polymorphism and fatal cerebral malaria. Lancet (1998) 1.35

Model collaboration between hospitals and public health system to improve tuberculosis control in China. Int J Tuberc Lung Dis (2009) 1.33

Ski acts as a co-repressor with Smad2 and Smad3 to regulate the response to type beta transforming growth factor. Proc Natl Acad Sci U S A (2000) 1.32

Contribution of the CXC chemokines IP-10 and Mig to the antitumor effects of IL-12. J Leukoc Biol (1998) 1.32

Polymorphisms in E-cadherin (CDH1) result in a mis-localised cytoplasmic protein that is associated with Crohn's disease. Gut (2009) 1.31

Differences in elasticity of vinculin-deficient F9 cells measured by magnetometry and atomic force microscopy. Exp Cell Res (1998) 1.31

Saccharide-RNA recognition in a complex formed between neomycin B and an RNA aptamer. Structure (1999) 1.29

Bidirectional modulatory effect of orphanin FQ on morphine-induced analgesia: antagonism in brain and potentiation in spinal cord of the rat. Br J Pharmacol (1997) 1.28

Molecular cloning of human ABPL, an actin-binding protein homologue. Biochem Biophys Res Commun (1998) 1.26

Phox homology domains specifically bind phosphatidylinositol phosphates. Biochemistry (2001) 1.24

Activation of NADPH oxidase-related proton and electron currents in human eosinophils by arachidonic acid. J Physiol (2001) 1.24

Mice with very low expression of the vesicular monoamine transporter 2 gene survive into adulthood: potential mouse model for parkinsonism. Mol Cell Biol (2001) 1.24

Reported changes in health-related behaviours in Chinese urban residents in response to an influenza pandemic. Epidemiol Infect (2009) 1.23

Methamphetamine-induced cell death: selective vulnerability in neuronal subpopulations of the striatum in mice. Neuroscience (2006) 1.23

Sequence variants in the 5' flanking region of the leptin gene are associated with obesity in women. Ann Hum Genet (1999) 1.22

VEGF producing bone marrow stromal cells (BMSC) enhance vascularization and resorption of a natural coral bone substitute. Bone (2007) 1.21

Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1. J Biol Chem (2000) 1.20

The role of ataxin 10 in the pathogenesis of spinocerebellar ataxia type 10. Neurology (2006) 1.20

Genetic evidence for the neuronal nitric oxide synthase gene (NOS1) as a susceptibility locus for infantile pyloric stenosis. Am J Hum Genet (1996) 1.18

Genetic characterization of contemporary wild-type measles viruses from Vietnam and the People's Republic of China: identification of two genotypes within clade H. Virus Res (2001) 1.18

Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity. Proc Natl Acad Sci U S A (1995) 1.16

A locus on chromosome 7 determines myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice. Proc Natl Acad Sci U S A (1996) 1.15

Cytoplasmic localization of the oncogenic protein Ski in human cutaneous melanomas in vivo: functional implications for transforming growth factor beta signaling. Cancer Res (2001) 1.15

A new approach to 4-alkylthio-1,3-dithiole-2-thione: an unusual reaction of a zinc complex of 1,3-dithole-2-thione-4,5-dithiolate. Org Lett (2001) 1.13

Sam68, RNA helicase A and Tap cooperate in the post-transcriptional regulation of human immunodeficiency virus and type D retroviral mRNA. Oncogene (2000) 1.13

Study of soybean seed coat components and their relationship to water absorption. J Agric Food Chem (2001) 1.12

Synthesis and antibacterial activities of quaternary ammonium salt of chitosan. Carbohydr Res (2001) 1.12

Two novel BRM insertion promoter sequence variants are associated with loss of BRM expression and lung cancer risk. Oncogene (2011) 1.12

Characterization of a new tissue-engineered human skin equivalent with hair. In Vitro Cell Dev Biol Anim (1999) 1.12

Formation of isomorphic desolvates: creating a molecular vacuum. J Pharm Sci (1998) 1.12

Peptide-triggered conformational switch in HIV-1 RRE RNA complexes. Nat Struct Biol (2001) 1.11

Metastable structures and recombination pathways for atomic hydrogen on the graphite (0001) surface. Phys Rev Lett (2006) 1.11

Subpopulations of MCF7 cells separated by Percoll gradient centrifugation: a model to analyze the heterogeneity of human breast cancer. Proc Natl Acad Sci U S A (1987) 1.10

Ultrafast primary processes in photosystem I of the cyanobacterium Synechocystis sp. PCC 6803. Biophys J (1999) 1.10

Antidepressant pharmacotherapy helps some cigarette smokers more than others. J Consult Clin Psychol (1999) 1.09

In vivo functions of histone acetylation/deacetylation in Tup1p repression and Gcn5p activation. Cold Spring Harb Symp Quant Biol (1998) 1.09

Genotyping and functional analysis of a polymorphic (CCTTT)(n) repeat of NOS2A in diabetic retinopathy. FASEB J (1999) 1.09

Tanshinone II A attenuates inflammatory responses of rats with myocardial infarction by reducing MCP-1 expression. Phytomedicine (2009) 1.08

Three residues involved in binding and catalysis in the carbamyl phosphate binding site of Escherichia coli aspartate transcarbamylase. Biochemistry (1989) 1.08

Eosin, a potent inhibitor of the plasma membrane Ca pump, does not inhibit the cardiac Na-Ca exchanger. Biochemistry (1995) 1.08