The role of allergy in the development of asthma.

PubWeight™: 1.88‹?› | Rank: Top 3%

🔗 View Article (PMID 10586890)

Published in Nature on November 25, 1999

Authors

P G Holt1, C Macaubas, P A Stumbles, P D Sly

Author Affiliations

1: TVW Telethon Institute for Child Health Research, Perth, WA, Australia.

Articles citing this

Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J Exp Med (2004) 4.34

Suppression of allergic airway inflammation by helminth-induced regulatory T cells. J Exp Med (2005) 3.63

A second-generation genomewide screen for asthma-susceptibility alleles in a founder population. Am J Hum Genet (2000) 2.62

Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice. J Exp Med (2000) 2.46

Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells. Proc Natl Acad Sci U S A (2006) 2.34

The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses. J Immunol (2011) 2.33

Eosinophils generate brominating oxidants in allergen-induced asthma. J Clin Invest (2000) 2.05

Epigenetic mechanisms and the development of asthma. J Allergy Clin Immunol (2012) 1.67

The increased prevalence of allergy and the hygiene hypothesis: missing immune deviation, reduced immune suppression, or both? Immunology (2004) 1.65

Relationship between African dust carried in the Atlantic trade winds and surges in pediatric asthma attendances in the Caribbean. Int J Biometeorol (2008) 1.58

Potential therapeutic role for statins in respiratory disease. Thorax (2006) 1.49

Suppressor of Cytokine Signaling (SOCS)1 Regulates Interleukin-4 (IL-4)-activated Insulin Receptor Substrate (IRS)-2 Tyrosine Phosphorylation in Monocytes and Macrophages via the Proteasome. J Biol Chem (2016) 1.41

House dust (1-3)-beta-D-glucan and wheezing in infants. Allergy (2007) 1.40

Bidirectional interactions between antigen-bearing respiratory tract dendritic cells (DCs) and T cells precede the late phase reaction in experimental asthma: DC activation occurs in the airway mucosa but not in the lung parenchyma. J Exp Med (2003) 1.39

Fiber-optic microsphere-based antibody array for the analysis of inflammatory cytokines in saliva. Anal Chem (2009) 1.35

Asthma-related environmental fungus, Alternaria, activates dendritic cells and produces potent Th2 adjuvant activity. J Immunol (2009) 1.26

Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma. Am J Pathol (2004) 1.22

Adoptive transfer of IL-4Rα+ macrophages is sufficient to enhance eosinophilic inflammation in a mouse model of allergic lung inflammation. BMC Immunol (2012) 1.21

A brief targeted review of susceptibility factors, environmental exposures, asthma incidence, and recommendations for future asthma incidence research. Environ Health Perspect (2006) 1.20

Household environmental tobacco smoke and risks of asthma, wheeze and bronchitic symptoms among children in Taiwan. Respir Res (2010) 1.19

Asthma families show transmission disequilibrium of gene variants in the vitamin D metabolism and signalling pathway. Respir Res (2006) 1.18

Prevalence and determinants of asthma in adult male leather tannery workers in Karachi, Pakistan: a cross sectional study. BMC Public Health (2006) 1.11

A review of anti-IgE monoclonal antibody (omalizumab) as add on therapy for severe allergic (IgE-mediated) asthma. Ther Clin Risk Manag (2007) 1.11

Eosinophil cytokines, chemokines, and growth factors: emerging roles in immunity. Front Immunol (2014) 1.08

Attenuated allergic airway hyperresponsiveness in C57BL/6 mice is associated with enhanced surfactant protein (SP)-D production following allergic sensitization. Respir Res (2003) 1.05

Infection with Syphacia obvelata (pinworm) induces protective Th2 immune responses and influences ovalbumin-induced allergic reactions. Infect Immun (2006) 1.02

Maternal transmission of resistance to development of allergic airway disease. J Immunol (2007) 0.99

Signaling networks controlling mucin production in response to Gram-positive and Gram-negative bacteria. Glycoconj J (2001) 0.98

Common variants of the vitamin D binding protein gene and adverse health outcomes. Crit Rev Clin Lab Sci (2013) 0.98

Invited commentary: does neonatal hyperbilirubinemia cause asthma? Am J Epidemiol (2013) 0.93

Ecogenomics of respiratory diseases of public health significance. Annu Rev Public Health (2010) 0.91

Immunopathogenesis of allergic asthma: more than the th2 hypothesis. Allergy Asthma Immunol Res (2013) 0.90

Cellular and cytokine immunoregulation in patients with chronic obstructive pulmonary disease and bronchial asthma. Mediators Inflamm (2002) 0.89

IgE-dependent enhancement of Th2 cell-mediated allergic inflammation in the airways. Clin Exp Immunol (2004) 0.88

Association of short-term increases in ambient air pollution and timing of initial asthma diagnosis among Medicaid-enrolled children in a metropolitan area. Environ Res (2014) 0.86

Glutathione reaction products with a chemical allergen, methylene-diphenyl diisocyanate, stimulate alternative macrophage activation and eosinophilic airway inflammation. Chem Res Toxicol (2015) 0.86

Allergic lung inflammation alters neither susceptibility to Streptococcus pneumoniae infection nor inducibility of innate resistance in mice. Respir Res (2009) 0.86

Identification of antigenic epitopes on human allergens: studies with HLA transgenic mice. Environ Health Perspect (2003) 0.86

Analysis of the mechanism by which melatonin inhibits human eosinophil peroxidase. Br J Pharmacol (2008) 0.84

Can intestinal helminth infections (geohelminths) affect the development and expression of asthma and allergic disease? Clin Exp Immunol (2002) 0.84

Atopy is a risk factor for adult asthma in urban community of Southwestern Nigeria. Lung India (2012) 0.84

The transcriptional regulator NFIL3 controls IgE production. Trans Am Clin Climatol Assoc (2010) 0.83

Expression and targeting of lymphocyte function-associated antigen 1 (LFA-1) on white blood cells for treatment of allergic asthma. J Leukoc Biol (2014) 0.83

Decreased prevalence of asthma among children with high exposure to cat allergen: relevance of the modified Th2 response. Mediators Inflamm (2001) 0.82

Nanoparticle conjugation enhances the immunomodulatory effects of intranasally delivered CpG in house dust mite-allergic mice. Sci Rep (2015) 0.81

Lebrikizumab in the personalized management of asthma. Biologics (2012) 0.81

Production of recombinant allergens in plants. Phytochem Rev (2008) 0.80

Problems in using incidence to analyze risk factors in follow-up studies. Eur J Epidemiol (2008) 0.79

Analysis of gene expression in peripheral blood eosinophils from patients with atopic dermatitis and in vitro cytokine-stimulated blood eosinophils. Clin Exp Immunol (2003) 0.78

Increased expression of glycodelin mRNA and protein in rat lungs during ovalbumin-induced allergic airway inflammation. Histochem Cell Biol (2008) 0.76

Allergic Responses Induced by a Fungal Biopesticide Metarhizium anisopliae and House Dust Mite Are Compared in a Mouse Model. J Toxicol (2011) 0.76

Tryptophan Metabolism in Allergic Disorders. Int Arch Allergy Immunol (2016) 0.75

Role of Epigenetics in Biology and Human Diseases. Iran Biomed J (2016) 0.75

'The Microbiome and the Pathophysiology of Asthma'. Respir Res (2016) 0.75

Population-based efficacy modeling of omalizumab in patients with severe allergic asthma inadequately controlled with standard therapy. AAPS J (2013) 0.75

Atopic dermatitis: a paradigmatic allergic skin disease. Mediators Inflamm (2001) 0.75

Effect and mechanism of lipopolysaccharide on allergen-induced interleukin-5 and eotaxins production by whole blood cultures of atopic asthmatics. Clin Exp Immunol (2007) 0.75

Clinical characteristics and long-term outcomes related to sputum eosinophilia in Korean asthmatics. Asia Pac Allergy (2011) 0.75

The real world effect of omalizumab add on therapy for patients with moderate to severe allergic asthma: The ASTERIX Observational study. PLoS One (2017) 0.75

An Overlook to the Characteristics and Roles Played by Eotaxin Network in the Pathophysiology of Food Allergies: Allergic Asthma and Atopic Dermatitis. Inflammation (2016) 0.75

Articles by these authors

Development of allergen-specific T-cell memory in atopic and normal children. Lancet (1999) 4.34

Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. Eur Respir J (2008) 3.36

Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T cell responses toward the Th2 cytokine profile. J Immunol (1998) 2.53

An immunoepidemiological approach to asthma: identification of in-vitro T-cell response patterns associated with different wheezing phenotypes in children. Lancet (2005) 2.39

Association between breast feeding and asthma in 6 year old children: findings of a prospective birth cohort study. BMJ (1999) 2.34

Effects of maternal smoking during pregnancy and a family history of asthma on respiratory function in newborn infants. Lancet (1996) 2.33

Vitamin D and atopy and asthma phenotypes in children: a longitudinal cohort study. Eur Respir J (2011) 2.21

Dendritic cells are recruited into the airway epithelium during the inflammatory response to a broad spectrum of stimuli. J Exp Med (1996) 2.19

Association between antenatal cytokine production and the development of atopy and asthma at age 6 years. Lancet (2003) 2.09

Mutation rate varies among alleles at a microsatellite locus: phylogenetic evidence. Proc Natl Acad Sci U S A (1996) 1.96

International consensus on (ICON) pediatric asthma. Allergy (2012) 1.79

Ovalbumin-sensitized mice are good models for airway hyperresponsiveness but not acute physiological responses to allergen inhalation. Clin Exp Allergy (2007) 1.79

TH2-polarized immunological memory to inhalant allergens in atopics is established during infancy and early childhood. Clin Exp Allergy (1997) 1.77

Allergic respiratory disease: strategic targets for primary prevention during childhood. Thorax (1997) 1.76

Modification of the inflammatory response to allergen challenge after exposure to bacterial lipopolysaccharide. Am J Respir Cell Mol Biol (2000) 1.70

Dose and time response after intraamniotic endotoxin in preterm lambs. Am J Respir Crit Care Med (2001) 1.69

Altered stability of pulmonary surfactant in SP-C-deficient mice. Proc Natl Acad Sci U S A (2001) 1.68

Febrile respiratory illnesses in infancy and atopy are risk factors for persistent asthma and wheeze. Eur Respir J (2011) 1.65

Breast feeding and respiratory morbidity in infancy: a birth cohort study. Arch Dis Child (2003) 1.60

Atopic versus infectious diseases in childhood: a question of balance? Pediatr Allergy Immunol (1997) 1.60

Th2-associated immunity to bacteria in teenagers and susceptibility to asthma. Eur Respir J (2010) 1.58

Home recording of peak expiratory flow rates and perception of asthma. Am J Dis Child (1985) 1.57

Suppression of the asthmatic phenotype by ultraviolet B-induced, antigen-specific regulatory cells. Clin Exp Allergy (2007) 1.54

The transient value of classifying preschool wheeze into episodic viral wheeze and multiple trigger wheeze. Acta Paediatr (2010) 1.49

Animal models of asthma. Clin Exp Allergy (2007) 1.49

Cyanide in bronchoalveolar lavage is not diagnostic for Pseudomonas aeruginosa in children with cystic fibrosis. Eur Respir J (2010) 1.47

A national policy on asthma management for schools. The Asthma Special Interest Group, Thoracic Society of Australia and New Zealand. J Paediatr Child Health (1994) 1.45

The role of corticosteroids in the management of childhood asthma. The Thoracic Society of Australia and New Zealand. Med J Aust (1992) 1.45

Heterogeneity in diphtheria-tetanus-acellular pertussis vaccine-specific cellular immunity during infancy: relationship to variations in the kinetics of postnatal maturation of systemic th1 function. J Infect Dis (2001) 1.42

Respiratory mechanics during sevoflurane anesthesia in children with and without asthma. Anesth Analg (1999) 1.41

Effect of misoprostol on fat malabsorption in cystic fibrosis. Arch Dis Child (1988) 1.41

Frequent nocturnal awakening in early life is associated with nonatopic asthma in children. Eur Respir J (2009) 1.41

Measurement of lung function in preschool children using the interrupter technique. Thorax (2003) 1.40

The effects of respiratory infections, atopy, and breastfeeding on childhood asthma. Eur Respir J (2002) 1.35

Factors predisposing to abnormal pulmonary function after adenovirus type 7 pneumonia. Arch Dis Child (1984) 1.33

Pressure flow characteristics of the valve in spacer devices. Arch Dis Child (1989) 1.29

Development of long-term tolerance versus sensitisation to environmental allergens during the perinatal period. Curr Opin Immunol (1997) 1.28

The influence of age on aerosol deposition in children with cystic fibrosis. Eur Respir J (1994) 1.25

Antigen-specific responses to diphtheria-tetanus-acellular pertussis vaccine in human infants are initially Th2 polarized. Infect Immun (2000) 1.22

DQB1*0602 and DQA1*0102 (DQ1) are better markers than DR2 for narcolepsy in Caucasian and black Americans. Sleep (1994) 1.21

Antenatal endotoxin and glucocorticoid effects on lung morphometry in preterm lambs. Pediatr Res (2000) 1.19

Acquisition and eradication of P. aeruginosa in young children with cystic fibrosis. Eur Respir J (2008) 1.18

Reciprocal age-related patterns of allergen-specific T-cell immunity in normal vs. atopic infants. Clin Exp Allergy (1998) 1.16

Diurnal variation of peak expiratory flow rate in asthmatic children. Pediatr Pulmonol (1986) 1.13

Interactions between RSV infection, asthma, and atopy: unraveling the complexities. J Exp Med (2002) 1.11

Nonatopic asthma is associated with helminth infections and bronchiolitis in poor children. Eur Respir J (2007) 1.10

Overexpression of TGF-alpha increases lung tissue hysteresivity in transgenic mice. J Appl Physiol (1985) (2001) 1.10

Methacholine-induced bronchoconstriction in rats: effects of intravenous vs. aerosol delivery. J Appl Physiol (1985) (1997) 1.10

Regulation of T-helper cell responses to inhalant allergen during early childhood. Clin Exp Allergy (1999) 1.09

Policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich et al. Endocrinology (2013) 1.08

Toll-like receptor 7 function is reduced in adolescents with asthma. Eur Respir J (2009) 1.08

Home oxygen management of neonatal chronic lung disease in Western Australia. J Paediatr Child Health (1995) 1.06

Pulmonary interstitial emphysema 24 hours after antenatal betamethasone treatment in preterm sheep. Am J Respir Crit Care Med (2000) 1.05

Laser monitoring of chest wall displacement. Eur Respir J (1997) 1.03

Bronchodilator response during acute viral bronchiolitis in infancy. Pediatr Pulmonol (1985) 1.03

Developing patterns of T cell memory to environmental allergens in the first two years of life. Int Arch Allergy Immunol (1997) 1.01

Alveolar macrophages and CC chemokines are increased in children with cystic fibrosis. Eur Respir J (2009) 1.00

Inhalation of hypertonic saline as a bronchial challenge in children with mild asthma and normal children. J Allergy Clin Immunol (1989) 0.99

Reliable tidal volume estimates at the airway opening with an infant monitor during high-frequency oscillatory ventilation. Crit Care Med (2001) 0.98

T-cell "priming" against environmental allergens in human neonates: sequential deletion of food antigen reactivity during infancy with concomitant expansion of responses to ubiquitous inhalant allergens. Pediatr Allergy Immunol (1995) 0.98

Boosting airway T-regulatory cells by gastrointestinal stimulation as a strategy for asthma control. Mucosal Immunol (2010) 0.98

Reference values of interrupter respiratory resistance in healthy preschool white children. Thorax (2001) 0.98

Regulation of immunologic homeostasis in peripheral tissues by dendritic cells: the respiratory tract as a paradigm. J Allergy Clin Immunol (2000) 0.97

Specific patterns of responsiveness to microbial antigens staphylococcal enterotoxin B and purified protein derivative by cord blood mononuclear cells are predictive of risk for development of atopic dermatitis. Clin Exp Allergy (2003) 0.97

Improved detection of abnormal respiratory function using forced expiration from raised lung volume in infants with cystic fibrosis. Eur Respir J (1994) 0.96

Lung morphometry after repetitive antenatal glucocorticoid treatment in preterm sheep. Am J Respir Crit Care Med (2001) 0.95

Control of breathing in infants born to smoking mothers. J Pediatr (1999) 0.95

Differential effects of nitric oxide synthase inhibitors in an in vivo allergic rat model. Eur Respir J (2000) 0.95

Prevention of adult asthma by early intervention during childhood: potential value of new generation immunomodulatory drugs. Thorax (2000) 0.94

Pre-flight testing of preterm infants with neonatal lung disease: a retrospective review. Thorax (2006) 0.93

Validation of respiratory inductance plethysmography ("Respitrace") for the measurement of tidal breathing parameters in newborns. Pediatr Pulmonol (1992) 0.93

Characterization of dendritic cell populations in the respiratory tract. J Aerosol Med (2000) 0.93

Improved safety with equivalent asthma control in adults with chronic severe asthma on high-dose fluticasone propionate. Respirology (2001) 0.93

Inherent variability of pulmonary function tests in infants with bronchiolitis. Pediatr Pulmonol (1988) 0.92

Neutrophilic airway inflammation is a main feature of induced sputum in nonatopic asthmatic children. Allergy (2009) 0.92

Correlation of forced oscillation technique in preschool children with cystic fibrosis with pulmonary inflammation. Thorax (2005) 0.92

A new technique to generate and assess forced expiration from raised lung volume in infants. Am J Respir Crit Care Med (1995) 0.91

Effect of valve closure time on the determination of respiratory resistance by flow interruption. Med Biol Eng Comput (1987) 0.91

Sunshine, rainfall, humidity and child pneumonia in the tropics: time-series analyses. Epidemiol Infect (2012) 0.90

Influence of nonlinearities on estimates of respiratory mechanics using multilinear regression analysis. J Appl Physiol (1985) (1994) 0.90

Acute Influenza A infection induces bronchial hyper-responsiveness in mice. Respir Physiol Neurobiol (2008) 0.89

Interrupter resistance elucidated by alveolar pressure measurement in open-chest normal dogs. J Appl Physiol (1985) (1988) 0.89

Validation of esophageal pressure occlusion test after paralysis. Pediatr Pulmonol (1994) 0.89

Antibiotic use in the first year of life and risk of atopic disease in early childhood. Clin Exp Allergy (2008) 0.89

Lung morphometry and collagen and elastin content: changes during normal development and after prenatal hormone exposure in sheep. Pediatr Res (1999) 0.89

Viscosity and density of common anaesthetic gases: implications for flow measurements. Br J Anaesth (2001) 0.89

Development of immunologic memory against tetanus toxoid and pertactin antigens from the diphtheria-tetanus-pertussis vaccine in atopic versus nonatopic children. J Allergy Clin Immunol (2000) 0.88

Standards for infant respiratory function testing: what(ever) next? Eur Respir J (2000) 0.88

The effects of inhaled beclomethasone dipropionate on lung function and histamine responsiveness in recurrently wheezy infants. Arch Dis Child (1995) 0.88

Elemental carbon exposure and lung function in school children from Mexico City. Eur Respir J (2011) 0.87

Interactions between respiratory tract infections and atopy in the aetiology of asthma. Eur Respir J (2002) 0.87

Allergen-induced cytokine secretion in relation to atopic symptoms and immunoglobulin E and immunoglobulin G subclass antibody responses. Pediatr Allergy Immunol (1999) 0.87

The complex mutation pattern of a microsatellite. Genome Res (1997) 0.87