Published in Eur Respir J on July 30, 2009
Toll-like receptor 7 agonists are potent and rapid bronchodilators in guinea pigs. J Allergy Clin Immunol (2010) 0.98
Viruses exacerbating chronic pulmonary disease: the role of immune modulation. BMC Med (2012) 0.95
Toll-like receptor 7 rapidly relaxes human airways. Am J Respir Crit Care Med (2013) 0.92
Association of Single Nucleotide Polymorphisms in Toll-like Receptor Genes With Asthma Risk: A Systematic Review and Meta-analysis. Allergy Asthma Immunol Res (2014) 0.92
Virus/allergen interactions and exacerbations of asthma. Immunol Allergy Clin North Am (2010) 0.91
Asthma is associated with multiple alterations in anti-viral innate signalling pathways. PLoS One (2014) 0.90
How do patients die in a rehabilitative unit dedicated to advanced respiratory diseases? Multidiscip Respir Med (2012) 0.89
TLR3, TLR4 and TLRs7-9 Induced Interferons Are Not Impaired in Airway and Blood Cells in Well Controlled Asthma. PLoS One (2013) 0.86
Toll-like receptor 7 governs interferon and inflammatory responses to rhinovirus and is suppressed by IL-5-induced lung eosinophilia. Thorax (2015) 0.86
Lessons learned in the analysis of high-dimensional data in vaccinomics. Vaccine (2015) 0.86
Budesonide and formoterol reduce early innate anti-viral immune responses in vitro. PLoS One (2011) 0.85
TLR3 and TLR7 modulate IgE production in antigen induced pulmonary inflammation via influencing IL-4 expression in immune organs. PLoS One (2011) 0.84
Adaptive immunity to rhinoviruses: sex and age matter. Respir Res (2010) 0.84
Repeated intranasal TLR7 stimulation reduces allergen responsiveness in allergic rhinitis. Respir Res (2012) 0.83
The therapeutic potential of Toll-like receptor 7 stimulation in asthma. Inflamm Allergy Drug Targets (2012) 0.83
Toll-like Receptor 7 Is Reduced in Severe Asthma and Linked to an Altered MicroRNA Profile. Am J Respir Crit Care Med (2016) 0.82
Interferon at the crossroads of allergy and viral infections. J Leukoc Biol (2015) 0.79
Rhinovirus stimulated IFN-α production: how important are plasmacytoid DCs, monocytes and endosomal pH? Clin Transl Immunology (2015) 0.76
IFN Deficiency in Asthma Attacks. Is Restoring Toll-like Receptor-7 Expression a New Treatment Approach in Severe Asthma? Am J Respir Crit Care Med (2016) 0.75
RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthma. Elife (2017) 0.75
Asthma Biomarkers: Do They Bring Precision Medicine Closer to the Clinic? Allergy Asthma Immunol Res (2017) 0.75
A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells. J Immunol Methods (1983) 4.39
Development of allergen-specific T-cell memory in atopic and normal children. Lancet (1999) 4.34
A Polymorphism* in the 5' flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E. Am J Respir Cell Mol Biol (1999) 3.42
Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. Eur Respir J (2008) 3.36
Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity. J Exp Med (1998) 2.85
Regulation of IgE responses to inhaled antigen in mice by antigen-specific gamma delta T cells. Science (1994) 2.66
Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T cell responses toward the Th2 cytokine profile. J Immunol (1998) 2.53
Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfaces. J Exp Med (1994) 2.52
Studies on the density, distribution, and surface phenotype of intraepithelial class II major histocompatibility complex antigen (Ia)-bearing dendritic cells (DC) in the conducting airways. J Exp Med (1991) 2.51
Down-regulation of immune responses in the lower respiratory tract: the role of alveolar macrophages. Clin Exp Immunol (1986) 2.43
An immunoepidemiological approach to asthma: identification of in-vitro T-cell response patterns associated with different wheezing phenotypes in children. Lancet (2005) 2.39
Association between breast feeding and asthma in 6 year old children: findings of a prospective birth cohort study. BMJ (1999) 2.34
Effects of maternal smoking during pregnancy and a family history of asthma on respiratory function in newborn infants. Lancet (1996) 2.33
Effect of cigarette smoking on primary and secondary humoral responses of mice. Nature (1973) 2.27
Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/STAT5 signaling pathway. J Immunol (1998) 2.25
Vitamin D and atopy and asthma phenotypes in children: a longitudinal cohort study. Eur Respir J (2011) 2.21
Dendritic cells are recruited into the airway epithelium during the inflammatory response to a broad spectrum of stimuli. J Exp Med (1996) 2.19
T cell activation by antigen-presenting cells from lung tissue digests: suppression by endogenous macrophages. Clin Exp Immunol (1985) 2.16
Reduced soluble receptor for advanced glycation end-products in COPD. Eur Respir J (2010) 2.09
Association between antenatal cytokine production and the development of atopy and asthma at age 6 years. Lancet (2003) 2.09
Immune and inflammatory function in cigarette smokers. Thorax (1987) 2.07
Inhibition of the immunosuppressive activity of resident pulmonary alveolar macrophages by granulocyte/macrophage colony-stimulating factor. J Exp Med (1993) 2.03
Preparation of interstitial lung cells by enzymatic digestion of tissue slices: preliminary characterization by morphology and performance in functional assays. Immunology (1985) 2.02
Inhibition of specific IgE responses in mice by pre-exposure to inhaled antigen. Immunology (1981) 2.01
Alveolar macrophages. I. A simple technique for the preparation of high numbers of viable alveolar macrophages from small laboratory animals. J Immunol Methods (1979) 1.98
Role of microbial burden in aetiology of allergy and asthma. Lancet (1999) 1.92
The role of allergy in the development of asthma. Nature (1999) 1.88
International consensus on (ICON) pediatric asthma. Allergy (2012) 1.79
Ovalbumin-sensitized mice are good models for airway hyperresponsiveness but not acute physiological responses to allergen inhalation. Clin Exp Allergy (2007) 1.79
TH2-polarized immunological memory to inhalant allergens in atopics is established during infancy and early childhood. Clin Exp Allergy (1997) 1.77
Allergic respiratory disease: strategic targets for primary prevention during childhood. Thorax (1997) 1.76
Induction of IgE-secreting cells and IgE isotype-specific suppressor T cells in the respiratory lymph nodes of rats in response to antigen inhalation. Cell Immunol (1985) 1.73
Modification of the inflammatory response to allergen challenge after exposure to bacterial lipopolysaccharide. Am J Respir Cell Mol Biol (2000) 1.70
Dose and time response after intraamniotic endotoxin in preterm lambs. Am J Respir Crit Care Med (2001) 1.69
Altered stability of pulmonary surfactant in SP-C-deficient mice. Proc Natl Acad Sci U S A (2001) 1.68
Febrile respiratory illnesses in infancy and atopy are risk factors for persistent asthma and wheeze. Eur Respir J (2011) 1.65
Maternal fish oil supplementation in pregnancy reduces interleukin-13 levels in cord blood of infants at high risk of atopy. Clin Exp Allergy (2003) 1.61
Breast feeding and respiratory morbidity in infancy: a birth cohort study. Arch Dis Child (2003) 1.60
Atopic versus infectious diseases in childhood: a question of balance? Pediatr Allergy Immunol (1997) 1.60
Regulation of immune response to inhaled antigen by alveolar macrophages: differential effects of in vivo alveolar macrophage elimination on the induction of tolerance vs. immunity. Eur J Immunol (1991) 1.59
Th2-associated immunity to bacteria in teenagers and susceptibility to asthma. Eur Respir J (2010) 1.58
Home recording of peak expiratory flow rates and perception of asthma. Am J Dis Child (1985) 1.57
Extraction of immune and inflammatory cells from human lung parenchyma: evaluation of an enzymatic digestion procedure. Clin Exp Immunol (1986) 1.57
Selective inhibition of T cell proliferation but not expression of effector function by human alveolar macrophages. Thorax (1997) 1.56
Suppression of the asthmatic phenotype by ultraviolet B-induced, antigen-specific regulatory cells. Clin Exp Allergy (2007) 1.54
Environmentally induced changes in immunological function: acute and chronic effects of inhalation of tobacco smoke and other atmospheric contaminants in man and experimental animals. Bacteriol Rev (1977) 1.51
The transient value of classifying preschool wheeze into episodic viral wheeze and multiple trigger wheeze. Acta Paediatr (2010) 1.49
Animal models of asthma. Clin Exp Allergy (2007) 1.49
Maternal reactivity to fetal alloantigens is related to newborn immune responses and subsequent allergic disease. Clin Exp Allergy (2005) 1.48
Functional characteristics of the veiled cells in afferent lymph from the rat intestine. Immunology (1986) 1.48
Cyanide in bronchoalveolar lavage is not diagnostic for Pseudomonas aeruginosa in children with cystic fibrosis. Eur Respir J (2010) 1.47
Rapid dendritic cell recruitment to the bronchial mucosa of patients with atopic asthma in response to local allergen challenge. Thorax (2001) 1.47
A national policy on asthma management for schools. The Asthma Special Interest Group, Thoracic Society of Australia and New Zealand. J Paediatr Child Health (1994) 1.45
The role of corticosteroids in the management of childhood asthma. The Thoracic Society of Australia and New Zealand. Med J Aust (1992) 1.45
Airways inflammation, atopy, and (1--> 3)-beta-D-glucan exposures in two schools. Am J Respir Crit Care Med (1998) 1.43
Heterogeneity in diphtheria-tetanus-acellular pertussis vaccine-specific cellular immunity during infancy: relationship to variations in the kinetics of postnatal maturation of systemic th1 function. J Infect Dis (2001) 1.42
Respiratory mechanics during sevoflurane anesthesia in children with and without asthma. Anesth Analg (1999) 1.41
Effect of misoprostol on fat malabsorption in cystic fibrosis. Arch Dis Child (1988) 1.41
Frequent nocturnal awakening in early life is associated with nonatopic asthma in children. Eur Respir J (2009) 1.41
Alveolar macrophages. II. Inhibition of lymphocyte proliferation by purified macrophages from rat lung. Immunology (1979) 1.40
Measurement of lung function in preschool children using the interrupter technique. Thorax (2003) 1.40
Maternal smoking in pregnancy alters neonatal cytokine responses. Allergy (2003) 1.40
The effects of respiratory infections, atopy, and breastfeeding on childhood asthma. Eur Respir J (2002) 1.35
Alveolar macrophages from humans and rodents selectively inhibit T-cell proliferation but permit T-cell activation and cytokine secretion. Immunology (1995) 1.34
Factors predisposing to abnormal pulmonary function after adenovirus type 7 pneumonia. Arch Dis Child (1984) 1.33
Regulation of IgE production in pre-sensitized animals: in vivo elimination of alveolar macrophages preferentially increases IgE responses to inhaled allergen. Clin Exp Allergy (1992) 1.30
Immunomorphologic studies of macrophages and MHC class II-positive dendritic cells in the iris and ciliary body of the rat, mouse, and human eye. Invest Ophthalmol Vis Sci (1994) 1.29
Pressure flow characteristics of the valve in spacer devices. Arch Dis Child (1989) 1.29
Alveolar macrophages. III. Studies on the mechanisms of inhibition of T-cell proliferation. Immunology (1979) 1.29
Cellular immunity in mice chronically exposed to fresh cigarette smoke. Arch Environ Health (1973) 1.28
Tolerance induction via antigen inhalation: isotype specificity, stability, and involvement of suppressor T cells. Int Arch Allergy Appl Immunol (1982) 1.27
Regulation of T-cell function in lung tissue by pulmonary alveolar macrophages. Immunology (1993) 1.27
Inhibitory activity of unstimulated alveolar macrophages on T-lymphocyte blastogenic response. Am Rev Respir Dis (1978) 1.27
Gamma delta T cells down-regulate primary IgE responses in rats to inhaled soluble protein antigens. J Immunol (1995) 1.27
The influence of age on aerosol deposition in children with cystic fibrosis. Eur Respir J (1994) 1.25
Induction of IgE-isotype specific tolerance by passive antigenic stimulation of the respiratory mucosa. Immunology (1983) 1.24
Alveolar macrophages. IV. Interspecies differences in activity in proliferating lymphocyte cultures. Cell Immunol (1980) 1.22
Antigen-specific responses to diphtheria-tetanus-acellular pertussis vaccine in human infants are initially Th2 polarized. Infect Immun (2000) 1.22
Antenatal endotoxin and glucocorticoid effects on lung morphometry in preterm lambs. Pediatr Res (2000) 1.19