Published in Nucleic Acids Res on January 15, 2000
Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin. Nat Cell Biol (2001) 5.37
Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins. BMC Biochem (2001) 2.36
Replication origins in Xenopus egg extract Are 5-15 kilobases apart and are activated in clusters that fire at different times. J Cell Biol (2001) 2.07
The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation. J Cell Biol (2004) 1.89
Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus. EMBO J (2004) 1.84
MCM2-7 form double hexamers at licensed origins in Xenopus egg extract. J Biol Chem (2011) 1.55
Non-proteolytic inactivation of geminin requires CDK-dependent ubiquitination. Nat Cell Biol (2004) 1.45
Cell cycle-dependent regulation of the association between origin recognition proteins and somatic cell chromatin. EMBO J (2002) 1.14
Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1. Mol Biol Cell (2007) 1.09
A strong nucleotypic effect on the cell cycle regardless of ploidy level. Ann Bot (2008) 1.07
Functional cooperation between FACT and MCM is coordinated with cell cycle and differential complex formation. J Biomed Sci (2010) 0.86
Depletion of Uhrf1 inhibits chromosomal DNA replication in Xenopus egg extracts. Nucleic Acids Res (2013) 0.86
GON4L Drives Cancer Growth through a YY1-Androgen Receptor-CD24 Axis. Cancer Res (2016) 0.78
The Drosophila nuclear lamina protein YA binds to DNA and histone H2B with four domains. Mol Biol Cell (2002) 0.77
Presence of the Paternal Pronucleus Assists Embryo in Overcoming Cycloheximide Induced Abnormalities in Zygotic Mitosis. J Cell Biochem (2016) 0.75
The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines. Cell Chem Biol (2017) 0.75
ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex. Nature (1992) 11.06
Geminin, an inhibitor of DNA replication, is degraded during mitosis. Cell (1998) 6.69
Two steps in the assembly of complexes at yeast replication origins in vivo. Cell (1994) 6.42
A polypeptide domain that specifies migration of nucleoplasmin into the nucleus. Cell (1982) 6.39
Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs. Cell (1986) 5.96
Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast. Proc Natl Acad Sci U S A (1997) 5.51
A role for the nuclear envelope in controlling DNA replication within the cell cycle. Nature (1988) 5.41
The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts. Cell (1996) 4.80
Nucleosomes are assembled by an acidic protein which binds histones and transfers them to DNA. Nature (1978) 4.56
Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes. Cell (1991) 4.33
Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants. Genes Dev (1997) 4.27
Regulated replication of DNA microinjected into eggs of Xenopus laevis. Cell (1980) 4.24
Purification of an MCM-containing complex as a component of the DNA replication licensing system. Nature (1995) 4.00
Identification of the yeast MCM3-related protein as a component of Xenopus DNA replication licensing factor. Cell (1995) 3.47
Interaction between the origin recognition complex and the replication licensing system in Xenopus. Cell (1996) 3.45
p65cdc18 plays a major role controlling the initiation of DNA replication in fission yeast. Cell (1995) 3.29
Once and only once upon a time: specifying and regulating origins of DNA replication in eukaryotic cells. Genes Dev (1996) 3.15
The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin. Curr Biol (1996) 2.89
A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts. Cell (1990) 2.84
MCM proteins: evolution, properties, and role in DNA replication. Biochim Biophys Acta (1998) 2.73
Cell cycle regulation of the replication licensing system: involvement of a Cdk-dependent inhibitor. J Cell Biol (1997) 2.58
Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2. J Cell Biol (1998) 2.51
Changes in association of the Xenopus origin recognition complex with chromatin on licensing of replication origins. J Cell Sci (1999) 2.51
The role of MCM/P1 proteins in the licensing of DNA replication. Trends Biochem Sci (1996) 2.44
Preventing re-replication of DNA in a single cell cycle: evidence for a replication licensing factor. J Cell Biol (1993) 2.44
Role for a Xenopus Orc2-related protein in controlling DNA replication. Nature (1996) 2.44
Two complexes that contain histones are required for nucleosome assembly in vitro: role of nucleoplasmin and N1 in Xenopus egg extracts. Cell (1987) 2.43
Acidic polypeptides can assemble both histones and chromatin in vitro at physiological ionic strength. Proc Natl Acad Sci U S A (1979) 2.33
The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides. EMBO J (1997) 2.27
Chromosomal replication initiates and terminates at random sequences but at regular intervals in the ribosomal DNA of Xenopus early embryos. EMBO J (1993) 2.27
An acidic protein which assembles nucleosomes in vitro is the most abundant protein in Xenopus oocyte nuclei. J Mol Biol (1980) 2.25
Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases. Curr Biol (1994) 1.95
Sperm decondensation in Xenopus egg cytoplasm is mediated by nucleoplasmin. Cell (1991) 1.91
Characterization of the Xenopus replication licensing system. Methods Enzymol (1997) 1.88
Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity. J Biol Chem (2000) 1.84
DNA replication initiates at multiple sites on plasmid DNA in Xenopus egg extracts. Nucleic Acids Res (1992) 1.84
Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs. EMBO J (1997) 1.83
Determination of initiation of DNA replication before and after nuclear formation in Xenopus egg cell free extracts. J Cell Biol (1993) 1.78
Co-existence of two different types of soluble histone complexes in nuclei of Xenopus laevis oocytes. J Biol Chem (1985) 1.76
Plasmid replication in Xenopus eggs and egg extracts: a 2D gel electrophoretic analysis. Nucleic Acids Res (1992) 1.73
Nucleoplasmin remodels sperm chromatin in Xenopus egg extracts. Cell (1992) 1.70
Soluble acidic complexes containing histones H3 and H4 in nuclei of Xenopus laevis oocytes. Cell (1982) 1.60
Binding of human minichromosome maintenance proteins with histone H3. J Biol Chem (1996) 1.45
Nucleosome assembly in vitro: separate histone transfer and synergistic interaction of native histone complexes purified from nuclei of Xenopus laevis oocytes. EMBO J (1990) 1.41
The RLF-B component of the replication licensing system is distinct from Cdc6 and functions after Cdc6 binds to chromatin. Curr Biol (1999) 1.41
Ribonucleic acid and other polyanions facilitate chromatin assembly in vitro. Biochemistry (1981) 1.32
Xenopus nucleoplasmin: egg vs. oocyte. Biochemistry (1986) 1.18
Swelling of hen erythrocyte nuclei in cytoplasm from Xenopus eggs. Exp Cell Res (1972) 1.12
The replication licensing system. Biol Chem (1998) 1.11
Hyperphosphorylation of nucleoplasmin facilitates Xenopus sperm decondensation at fertilization. J Biol Chem (1996) 1.03
Histone H1 reduces the frequency of initiation in Xenopus egg extract by limiting the assembly of prereplication complexes on sperm chromatin. Mol Biol Cell (1998) 0.97
Nucleoplasmin: the archetypal molecular chaperone. Semin Cell Biol (1990) 0.97
Histone H1 modulates DNA replication through multiple pathways in Xenopus egg extract. J Cell Sci (1997) 0.89
Characterization of spermatid/sperm basic chromosomal proteins in the genus Xenopus (Anura, Pipidae). J Exp Zool (1982) 0.80
Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. Eur J Biochem (1997) 6.99
Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs. Cell (1986) 5.96
Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin. Nat Cell Biol (2001) 5.37
Translation of cyclin mRNA is necessary for extracts of activated xenopus eggs to enter mitosis. Cell (1989) 4.56
Purification of an MCM-containing complex as a component of the DNA replication licensing system. Nature (1995) 4.00
Interaction between the origin recognition complex and the replication licensing system in Xenopus. Cell (1996) 3.45
The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin. Curr Biol (1996) 2.89
Inhibition of cyclin-dependent kinases by purine analogues. Eur J Biochem (1994) 2.82
Cell cycle regulation of the replication licensing system: involvement of a Cdk-dependent inhibitor. J Cell Biol (1997) 2.58
Changes in association of the Xenopus origin recognition complex with chromatin on licensing of replication origins. J Cell Sci (1999) 2.51
The role of MCM/P1 proteins in the licensing of DNA replication. Trends Biochem Sci (1996) 2.44
Steps in the assembly of replication-competent nuclei in a cell-free system from Xenopus eggs. J Cell Biol (1988) 2.44
Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins. BMC Biochem (2001) 2.36
The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides. EMBO J (1997) 2.27
Xenopus cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading. Genes Dev (2000) 2.10
Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases. Curr Biol (1994) 1.95
Characterization of the Xenopus replication licensing system. Methods Enzymol (1997) 1.88
DNA replication initiates at multiple sites on plasmid DNA in Xenopus egg extracts. Nucleic Acids Res (1992) 1.84
Replication occurs at discrete foci spaced throughout nuclei replicating in vitro. J Cell Sci (1989) 1.84
Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity. J Biol Chem (2000) 1.84
Cell cycle control of replication initiation in eukaryotes. Curr Opin Cell Biol (1996) 1.77
Both cyclin A and cyclin E have S-phase promoting (SPF) activity in Xenopus egg extracts. J Cell Sci (1996) 1.61
S phase of the cell cycle. Science (1989) 1.59
The Cdc7/Dbf4 protein kinase: target of the S phase checkpoint? EMBO Rep (2000) 1.41
The RLF-B component of the replication licensing system is distinct from Cdc6 and functions after Cdc6 binds to chromatin. Curr Biol (1999) 1.41
Cip1 inhibits DNA replication but not PCNA-dependent nucleotide excision-repair. Curr Biol (1994) 1.31
Chromatin proteins involved in the initiation of DNA replication. Curr Opin Genet Dev (1997) 1.26
The regulation of replication origin activation. Curr Opin Genet Dev (1999) 1.20
Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing. Proc Natl Acad Sci U S A (2009) 1.14
The replication licensing system. Biol Chem (1998) 1.11
The replication capacity of intact mammalian nuclei in Xenopus egg extracts declines with quiescence, but the residual DNA synthesis is independent of Xenopus MCM proteins. J Cell Sci (2000) 1.07
Interaction of Xenopus Cdc2 x cyclin A1 with the origin recognition complex. J Biol Chem (2000) 1.02
Use of peptides from p21 (Waf1/Cip1) to investigate PCNA function in Xenopus egg extracts. Exp Cell Res (2001) 0.94
The use of field emission in-lens scanning electron microscopy to study the steps of assembly of the nuclear envelope in vitro. J Struct Biol (1993) 0.92
Postural effects on intra-abdominal pressure during Valsalva maneuver. Arch Phys Med Rehabil (1994) 0.89
The origin of CDK regulation. Nat Cell Biol (2001) 0.88
The DNA replication licensing system. Cancer Surv (1997) 0.87
Site-specific initiation of DNA replication in metazoan chromosomes and the role of nuclear organization. Cold Spring Harb Symp Quant Biol (1993) 0.86
Saying a firm 'no' to DNA re-replication. Nat Cell Biol (1999) 0.82
DNA replication. Methyltransferases in foci. Nature (1993) 0.80
DNA replication licensing factor. Prog Cell Cycle Res (1996) 0.80
DNA replication: stable driving prevents fatal smashes. Curr Biol (2001) 0.79
Cell cycle. A new check on issuing the licence. Nature (2000) 0.79
Eukaryotic DNA replication reconstituted outside the cell. Bioessays (1988) 0.75