Published in Neuroscience on January 01, 1999
Neuregulin 1 and susceptibility to schizophrenia. Am J Hum Genet (2002) 7.40
Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndrome. J Comp Neurol (2010) 1.89
Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission. PLoS Biol (2011) 1.84
Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions. Curr Drug Targets (2006) 1.78
Targeted ablation of cholinergic interneurons in the dorsolateral striatum produces behavioral manifestations of Tourette syndrome. Proc Natl Acad Sci U S A (2015) 1.59
Executive function, neural circuitry, and genetic mechanisms in schizophrenia. Neuropsychopharmacology (2010) 1.47
Basal ganglia pathology in schizophrenia: dopamine connections and anomalies. J Neurochem (2010) 1.14
Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease. J Comp Neurol (2001) 1.11
Synthesis and in vitro and in vivo evaluation of 18F-labeled positron emission tomography (PET) ligands for imaging the vesicular acetylcholine transporter. J Med Chem (2009) 1.02
Targeting selective activation of M(1) for the treatment of Alzheimer's disease: further chemical optimization and pharmacological characterization of the M(1) positive allosteric modulator ML169. ACS Chem Neurosci (2012) 1.01
Psychiatric brain banking: three perspectives on current trends and future directions. Biol Psychiatry (2010) 1.00
Losing your inhibition: linking cortical GABAergic interneurons to schizophrenia. Neurobiol Dis (2012) 0.97
Cholinergic interneurons are differentially distributed in the human striatum. PLoS One (2007) 0.92
Synthesis and in vitro biological evaluation of carbonyl group-containing inhibitors of vesicular acetylcholine transporter. J Med Chem (2010) 0.91
Striatal cholinergic interneuron regulation and circuit effects. Front Synaptic Neurosci (2014) 0.91
GABAergic inputs from direct and indirect striatal projection neurons onto cholinergic interneurons in the primate putamen. J Comp Neurol (2013) 0.91
alpha7 Nicotinic acetylcholine receptors and temporal memory: synergistic effects of combining prenatal choline and nicotine on reinforcement-induced resetting of an interval clock. Learn Mem (2006) 0.90
Cholinergic connectivity: it's implications for psychiatric disorders. Front Cell Neurosci (2013) 0.89
Added donepezil for stable schizophrenia: a double-blind, placebo-controlled trial. Psychopharmacology (Berl) (2005) 0.88
Cholinergic circuits and signaling in the pathophysiology of schizophrenia. Int Rev Neurobiol (2007) 0.82
Mechanisms of action of antipsychotic drugs of different classes, refractoriness to therapeutic effects of classical neuroleptics, and individual variation in sensitivity to their actions: Part I. Curr Neuropharmacol (2009) 0.80
Discovery and SAR of muscarinic receptor subtype 1 (M1) allosteric activators from a molecular libraries high throughput screen. Part 1: 2,5-dibenzyl-2H-pyrazolo[4,3-c]quinolin-3(5H)-ones as positive allosteric modulators. Bioorg Med Chem Lett (2014) 0.80
Modulation of midbrain dopamine neurotransmission by serotonin, a versatile interaction between neurotransmitters and significance for antipsychotic drug action. Curr Neuropharmacol (2006) 0.79
Loss of VGLUT3 Produces Circadian-Dependent Hyperdopaminergia and Ameliorates Motor Dysfunction and l-Dopa-Mediated Dyskinesias in a Model of Parkinson's Disease. J Neurosci (2015) 0.77
Prefrontal gray matter morphology mediates the association between serum anticholinergicity and cognitive functioning in early course schizophrenia. Psychiatry Res (2012) 0.77
A Role for the Transcription Factor Nk2 Homeobox 1 in Schizophrenia: Convergent Evidence from Animal and Human Studies. Front Behav Neurosci (2016) 0.77
Brain in flames - animal models of psychosis: utility and limitations. Neuropsychiatr Dis Treat (2015) 0.76
Calretinin and parvalbumin in schizophrenia and affective disorders: a mini-review, a perspective on the evolutionary role of calretinin in schizophrenia, and a preliminary post-mortem study of calretinin in the septal nuclei. Front Cell Neurosci (2015) 0.75
Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell (1999) 9.84
A family of cAMP-binding proteins that directly activate Rap1. Science (1998) 6.12
Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity. Neuron (2001) 5.09
Differential expression of orexin receptors 1 and 2 in the rat brain. J Comp Neurol (2001) 4.88
Distributions of leptin receptor mRNA isoforms in the rat brain. J Comp Neurol (1998) 4.30
The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease. Brain (1999) 4.25
From lesions to leptin: hypothalamic control of food intake and body weight. Neuron (1999) 4.18
Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease. Brain (2007) 3.82
Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation. J Biol Chem (1998) 3.77
The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway. Nat Neurosci (2002) 3.52
Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area. Neuron (1999) 3.37
Activation of ventrolateral preoptic neurons during sleep. Science (1996) 3.27
Building neural representations of habits. Science (1999) 3.20
Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease. Nature (1988) 3.12
Fos expression in orexin neurons varies with behavioral state. J Neurosci (2001) 3.08
Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area. J Comp Neurol (1998) 3.01
To eat or to sleep? Orexin in the regulation of feeding and wakefulness. Annu Rev Neurosci (2001) 2.84
Melanopsin in cells of origin of the retinohypothalamic tract. Nat Neurosci (2001) 2.79
Schizophrenic subjects show aberrant fMRI activation of dorsolateral prefrontal cortex and basal ganglia during working memory performance. Biol Psychiatry (2000) 2.68
Efferent projections of the infralimbic cortex of the rat. J Comp Neurol (1991) 2.53
Connections of the parabrachial nucleus with the nucleus of the solitary tract and the medullary reticular formation in the rat. J Comp Neurol (1990) 2.52
Effect of lesions of the ventrolateral preoptic nucleus on NREM and REM sleep. J Neurosci (2000) 2.51
A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia. Proc Natl Acad Sci U S A (1998) 2.47
Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice. Cell (1994) 2.46
Leptin activates hypothalamic CART neurons projecting to the spinal cord. Neuron (1998) 2.46
Reduction of synapsin in the hippocampus of patients with bipolar disorder and schizophrenia. Mol Psychiatry (2002) 2.43
Midbrain dopaminergic cell loss in Parkinson's disease: computer visualization. Ann Neurol (1989) 2.33
Subnuclear organization of the efferent connections of the parabrachial nucleus in the rat. Brain Res (1984) 2.33
Concomitant loss of dynorphin, NARP, and orexin in narcolepsy. Neurology (2005) 2.33
Disseminated necrotizing leukoencephalopathy: a complication of treated central nervous system leukemia and lymphoma. Cancer (1975) 2.32
Interleukin-1 immunoreactive innervation of the human hypothalamus. Science (1988) 2.22
Direct hypothalamo-autonomic connections. Brain Res (1976) 2.21
Chemical characterization of leptin-activated neurons in the rat brain. J Comp Neurol (2000) 2.21
Innervation of histaminergic tuberomammillary neurons by GABAergic and galaninergic neurons in the ventrolateral preoptic nucleus of the rat. J Neurosci (1998) 2.21
Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia. Mol Psychiatry (2003) 2.18
Schizophrenic subjects activate dorsolateral prefrontal cortex during a working memory task, as measured by fMRI. Biol Psychiatry (1999) 2.17
Hypothalamic arousal regions are activated during modafinil-induced wakefulness. J Neurosci (2000) 2.16
Responses of tonically active neurons in the primate's striatum undergo systematic changes during behavioral sensorimotor conditioning. J Neurosci (1994) 2.14
Efferent connections of the parabrachial nucleus in the rat. Brain Res (1980) 2.13
Leptin regulation of neuroendocrine systems. Front Neuroendocrinol (2000) 2.12
Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression. Mol Psychiatry (2007) 2.12
Relative risk for cognitive impairments in siblings of patients with schizophrenia. Biol Psychiatry (2001) 2.08
Unraveling the central nervous system pathways underlying responses to leptin. Nat Neurosci (1998) 2.08
Treatment of tardive dyskinesia with vitamin E. Am J Psychiatry (1992) 2.07
Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses. Cell (1994) 2.05
Histochemically distinct compartments in the striatum of human, monkeys, and cat demonstrated by acetylthiocholinesterase staining. Proc Natl Acad Sci U S A (1978) 2.02
The substantia nigra of the human brain. I. Nigrosomes and the nigral matrix, a compartmental organization based on calbindin D(28K) immunohistochemistry. Brain (1999) 2.00
Neurons in the thalamic CM-Pf complex supply striatal neurons with information about behaviorally significant sensory events. J Neurophysiol (2001) 1.94
Binding of thyroglobulin and thyroglobulin-antithyroglobulin immune complex to extraocular muscle membrane. Endocrinology (1974) 1.92
Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei. Proc Natl Acad Sci U S A (1998) 1.92
Organization of visceral and limbic connections in the insular cortex of the rat. J Comp Neurol (1991) 1.91
Atriopeptins as cardiac hormones. Hypertension (1985) 1.91
Electron microscopic observations in infantile neuroaxonal dystrophy. Report of a cortical biopsy and review of the recent literature. Arch Neurol (1969) 1.90
Evidence for a viscerotopic sensory representation in the cortex and thalamus in the rat. J Comp Neurol (1987) 1.89
Mapping brain networks in awake mice using combined optical neural control and fMRI. J Neurophysiol (2010) 1.87
Recombinant adeno-associated virus vector: use for transgene expression and anterograde tract tracing in the CNS. Brain Res (1998) 1.84
Orexin (hypocretin) neurons contain dynorphin. J Neurosci (2001) 1.84
A measure of striatal function predicts motor stereotypy. Nat Neurosci (2000) 1.81
Leptin activates neurons in ventrobasal hypothalamus and brainstem. Endocrinology (1997) 1.81
Characterization of CART neurons in the rat and human hypothalamus. J Comp Neurol (2001) 1.80
Contrasts between patients with affective disorders and patients with schizophrenia on a neuropsychological test battery. Am J Psychiatry (1993) 1.78
The effect of clozapine on cognition and psychiatric symptoms in patients with schizophrenia. Br J Psychiatry (1993) 1.75
Catechol O-methyltransferase mRNA expression in human and rat brain: evidence for a role in cortical neuronal function. Neuroscience (2003) 1.74
A light- and electron-microscopic study of a temporal-lobe ganglioglioma. J Neurol Sci (1972) 1.73
Abnormal excitatory neurotransmitter metabolism in schizophrenic brains. Arch Gen Psychiatry (1995) 1.71
Convergence of autonomic and limbic connections in the insular cortex of the rat. J Comp Neurol (1982) 1.68
Distribution of Fos-like immunoreactivity in the rat brain following intravenous lipopolysaccharide administration. J Comp Neurol (1996) 1.68
Autonomic responses and efferent pathways from the insular cortex in the rat. J Comp Neurol (1991) 1.67
Common acute lymphoblastic leukemia antigen (CALLA) is active neutral endopeptidase 24.11 ("enkephalinase"): direct evidence by cDNA transfection analysis. Proc Natl Acad Sci U S A (1989) 1.67
Network-level changes in expression of inducible Fos-Jun proteins in the striatum during chronic cocaine treatment and withdrawal. Neuron (1996) 1.66
Electrophysiological evidence for excitation of rat ventral tegmental area dopamine neurons by morphine. Neuroscience (1984) 1.66
Two new proteases in the MHC class I processing pathway. Nat Immunol (2000) 1.63
Neuronal loss in the pedunculopontine tegmental nucleus in Parkinson disease and in progressive supranuclear palsy. Proc Natl Acad Sci U S A (1987) 1.62
Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia. Mol Psychiatry (2004) 1.62
Contrasting effects of ibotenate lesions of the paraventricular nucleus and subparaventricular zone on sleep-wake cycle and temperature regulation. J Neurosci (2001) 1.62
Methylamine metabolism in a pseudomonas species. Arch Biochem Biophys (1972) 1.58
Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics. Neuropsychopharmacology (1993) 1.58
Topographic organization of respiratory responses to glutamate microstimulation of the parabrachial nucleus in the rat. J Neurosci (1994) 1.58
Cortical projections arising from the basal forebrain: a study of cholinergic and noncholinergic components employing combined retrograde tracing and immunohistochemical localization of choline acetyltransferase. Neuroscience (1984) 1.52
Selective abnormalities of prefrontal serotonergic receptors in schizophrenia. A postmortem study. Arch Gen Psychiatry (1993) 1.52
Highly restricted origin of prefrontal cortical inputs to striosomes in the macaque monkey. J Neurosci (1995) 1.52
Temporal and spatial characteristics of tonically active neurons of the primate's striatum. J Neurophysiol (1995) 1.52
Effect of the nigrostriatal dopamine system on acquired neural responses in the striatum of behaving monkeys. Science (1994) 1.50
BDNF and trkB mRNA expression in the hippocampus and temporal cortex during the human lifespan. Gene Expr Patterns (2006) 1.48
CD10/neutral endopeptidase 24.11 hydrolyzes bombesin-like peptides and regulates the growth of small cell carcinomas of the lung. Proc Natl Acad Sci U S A (1991) 1.47
Choline acetyltransferase in schizophrenia. Am J Psychiatry (1993) 1.47
Catechol-o-methyltransferase enzyme activity and protein expression in human prefrontal cortex across the postnatal lifespan. Cereb Cortex (2006) 1.46
Monoclonal antibodies to study the brain in schizophrenia. Brain Res (1989) 1.45
The hydrolysis of endothelins by neutral endopeptidase 24.11 (enkephalinase). J Biol Chem (1990) 1.44
Dopamine D3 receptor mutant mice exhibit increased behavioral sensitivity to concurrent stimulation of D1 and D2 receptors. Neuron (1997) 1.44