The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway.

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Published in Nat Neurosci on October 01, 2002

Authors

L E Nelson1, T Z Guo, J Lu, C B Saper, N P Franks, M Maze

Author Affiliations

1: Department of Anaesthetics & Intensive Care, Chelsea & Westminster Hospital, Imperial College School of Medicine, London SW10 9NH, UK.

Associated clinical trials:

Monitoring of Adequate Course of General Anesthesia (MoDA) | NCT03331692

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