Published in J Biol Chem on April 14, 2000
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. BMC Med Genomics (2009) 2.36
Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction. Circulation (2008) 2.14
Dinitrosyliron complexes and the mechanism(s) of cellular protein nitrosothiol formation from nitric oxide. Proc Natl Acad Sci U S A (2009) 1.84
Nitric oxide induces CD4+CD25+ Foxp3 regulatory T cells from CD4+CD25 T cells via p53, IL-2, and OX40. Proc Natl Acad Sci U S A (2007) 1.45
Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases. Proc Natl Acad Sci U S A (2000) 1.44
Molecular optical imaging: applications leading to the development of present day therapeutics. NeuroRx (2005) 1.36
Nitrones as therapeutics. Free Radic Biol Med (2008) 1.35
Regulation of type 17 helper T-cell function by nitric oxide during inflammation. Proc Natl Acad Sci U S A (2011) 1.14
A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe. Neoplasia (2004) 1.11
Oxidative stress might play a role in low serum vitamin D associated liver fibrosis among patients with autoimmune hepatitis. Dig Dis Sci (2015) 1.07
Nitric oxide and redox regulation in the liver: Part I. General considerations and redox biology in hepatitis. J Surg Res (2009) 1.03
Role of galectin-3 in breast cancer metastasis: involvement of nitric oxide. Am J Pathol (2002) 1.01
Nitric oxide donors inhibit formation of the Apaf-1/caspase-9 apoptosome and activation of caspases. Biochem J (2003) 0.92
Nitric oxide-induced regulatory T cells inhibit Th17 but not Th1 cell differentiation and function. J Immunol (2013) 0.91
Endogenous nitric oxide activation protects against cigarette smoking induced apoptosis in endothelial cells. FEBS Lett (2005) 0.90
Cytotoxicity of 15-deoxy-Δ(12,14)-prostaglandin J(2) through PPARγ-independent pathway and the involvement of the JNK and Akt pathway in renal cell carcinoma. Int J Med Sci (2012) 0.90
HBx-induced reactive oxygen species activates hepatocellular carcinogenesis via dysregulation of PTEN/Akt pathway. World J Gastroenterol (2010) 0.89
Biophysical investigation of the ironome of human jurkat cells and mitochondria. Biochemistry (2012) 0.88
Computational insights on the competing effects of nitric oxide in regulating apoptosis. PLoS One (2008) 0.87
Nitric oxide and thioredoxin type 1 modulate the activity of caspase 8 in HepG2 cells. Biochem Biophys Res Commun (2009) 0.85
Iron-sulfur proteins are the major source of protein-bound dinitrosyl iron complexes formed in Escherichia coli cells under nitric oxide stress. Free Radic Biol Med (2011) 0.84
Hemoglobin: a nitric-oxide dioxygenase. Scientifica (Cairo) (2012) 0.83
Crucial role of lysosomal iron in the formation of dinitrosyl iron complexes in vivo. J Biol Inorg Chem (2006) 0.82
A Conspectus of Cellular Mechanisms of Nitrosothiol Formation from Nitric Oxide. For Immunopathol Dis Therap (2012) 0.81
Effect of IBD sera on expression of inducible and endothelial nitric oxide synthase in human umbilical vein endothelial cells. World J Gastroenterol (2006) 0.81
Oxygen is required for the L-cysteine-mediated decomposition of protein-bound dinitrosyl-iron complexes. Free Radic Biol Med (2010) 0.80
A review on hemeoxygenase-2: focus on cellular protection and oxygen response. Oxid Med Cell Longev (2014) 0.80
Cyclic AMP prolongs graft survival by suppressing apoptosis and inflammatory gene expression in acute cardiac allograft rejection. Exp Mol Med (2010) 0.79
Nitrogen monoxide (NO) storage and transport by dinitrosyl-dithiol-iron complexes: long-lived NO that is trafficked by interacting proteins. J Biol Chem (2012) 0.78
The prevention of endothelial dysfunction through endothelial cell apoptosis inhibition in a hypercholesterolemic rabbit model: the effect of L-arginine supplementation. Lipids Health Dis (2008) 0.77
Detecting and understanding the roles of nitric oxide in biology. Inorg Chem (2010) 0.77
Gelam honey scavenges peroxynitrite during the immune response. Int J Mol Sci (2012) 0.77
Electronic and spatial structures of water-soluble dinitrosyl iron complexes with thiol-containing ligands underlying their ability to act as nitric oxide and nitrosonium ion donors. J Biophys (2012) 0.76
Chemotaxis under agarose: a new and simple method for measuring chemotaxis and spontaneous migration of human polymorphonuclear leukocytes and monocytes. J Immunol (1975) 8.06
Virus-associated hemophagocytic syndrome: a benign histiocytic proliferation distinct from malignant histiocytosis. Cancer (1979) 5.60
Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat Med (2000) 4.40
Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science (1992) 3.80
Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin. J Exp Med (1992) 3.42
Cytomegalovirus disease in renal allograft recipients: a prospective study of the clinical features, risk factors and impact on renal transplantation. Medicine (Baltimore) (1980) 3.42
Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes. Proc Natl Acad Sci U S A (1993) 3.24
Inflammation, immunoregulation, and inducible nitric oxide synthase. J Leukoc Biol (1993) 3.07
Use of medical emergency team responses to reduce hospital cardiopulmonary arrests. Qual Saf Health Care (2004) 3.00
Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms. J Biol Chem (1997) 2.89
A randomized, placebo-controlled trial of oral acyclovir for the prevention of cytomegalovirus disease in recipients of renal allografts. N Engl J Med (1989) 2.78
Surgically induced leukocytic infiltrates within the rat intestinal muscularis mediate postoperative ileus. Gastroenterology (1999) 2.75
Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells. J Exp Med (1989) 2.49
Immunodepression after major surgery in normal patients. Surgery (1975) 2.48
Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes. Proc Natl Acad Sci U S A (1993) 2.46
Pancreatico-duodenal allotransplantation: experimental and clinical experience. Ann Surg (1970) 2.44
Epstein-Barr virus-induced B-cell lymphoma after renal transplantation: acyclovir therapy and transition from polyclonal to monoclonal B-cell proliferation. N Engl J Med (1982) 2.44
The impact of cyclosporine and combination immunosuppression on the incidence of posttransplant diabetes in renal allograft recipients. Transplantation (1987) 2.40
Multiple NF-kappaB enhancer elements regulate cytokine induction of the human inducible nitric oxide synthase gene. J Biol Chem (1998) 2.35
Epstein-Barr virus, immunodeficiency, and B cell lymphoproliferation. Transplantation (1985) 2.34
An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro. J Exp Med (1989) 2.27
Clinical spectrum of lymphoproliferative disorders in renal transplant recipients and evidence for the role of Epstein-Barr virus. Cancer Res (1981) 2.25
Nitrogen oxide levels in patients after trauma and during sepsis. Ann Surg (1991) 2.24
Proposed mechanisms for the translocation of intestinal bacteria. Rev Infect Dis (1988) 2.16
Frequent nitric oxide synthase-2 expression in human colon adenomas: implication for tumor angiogenesis and colon cancer progression. Cancer Res (1998) 2.15
Thymosin treatment of chronic hepatitis B: a placebo-controlled pilot trial. Hepatology (1991) 2.15
Modulation of nitrogen oxide synthesis in vivo: NG-monomethyl-L-arginine inhibits endotoxin-induced nitrate/nitrate biosynthesis while promoting hepatic damage. J Leukoc Biol (1990) 2.11
Bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition pores. Biophys J (2005) 2.09
Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide. J Immunol (1991) 2.07
New insights into the regulation of inducible nitric oxide synthesis. Am J Physiol (1994) 2.06
Nitric oxide-induced S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase inhibits enzymatic activity and increases endogenous ADP-ribosylation. J Biol Chem (1992) 2.03
Chemiluminescence response of phagocytizing human monocytes. Infect Immun (1976) 2.01
Surgical manipulation of the gut elicits an intestinal muscularis inflammatory response resulting in postsurgical ileus. Ann Surg (1998) 2.00
Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock. J Exp Med (1998) 1.96
Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation. Biochem Biophys Res Commun (1997) 1.87
Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury. Am J Transplant (2008) 1.86
Reversal of impaired wound repair in iNOS-deficient mice by topical adenoviral-mediated iNOS gene transfer. J Clin Invest (1998) 1.85
Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-alpha-induced apoptosis by inducing heat shock protein 70 expression. J Biol Chem (1997) 1.83
Association of renal allograft rejection with virus infections. Am J Med (1974) 1.83
Pancreatic trauma: a review. Surgery (1972) 1.81
Antiserum to lymphocytes: prolonged survival of canine renal allografts. Science (1966) 1.81
Essential role for IL-6 in postresuscitation inflammation in hemorrhagic shock. Am J Physiol Cell Physiol (2001) 1.81
Increased incidence of malignancy during chronic renal failure. Lancet (1975) 1.79
Family tension in the search for a kidney donor. JAMA (1971) 1.77
Chemiluminescence response of human leukocytes: influence of medium components on light production. Infect Immun (1977) 1.77
Attenuation of myocardial ischemia/reperfusion injury by superinduction of inducible nitric oxide synthase. Circulation (2000) 1.76
Alloantigen-induced activation of rat splenocytes is regulated by the oxidative metabolism of L-arginine. J Immunol (1990) 1.76
Multiple cytokines are required to induce hepatocyte nitric oxide production and inhibit total protein synthesis. Ann Surg (1990) 1.74
Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: initial analysis of the human NOS2 promoter. Proc Natl Acad Sci U S A (1996) 1.71
Recurrence of idiopathic nephrotic syndrome after renal transplantation. Lancet (1972) 1.71
Reactive nitrogen intermediates suppress the primary immunologic response to Listeria. J Immunol (1993) 1.69
Role of inducible nitric oxide synthase in postoperative intestinal smooth muscle dysfunction in rodents. Gastroenterology (2000) 1.69
Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53. Proc Natl Acad Sci U S A (1996) 1.68
Inducible cytosolic enzyme activity for the production of nitrogen oxides from L-arginine in hepatocytes. Biochem Biophys Res Commun (1990) 1.67
Molecular biology of nitric oxide synthases. Cancer Metastasis Rev (1998) 1.66
Hepatocellular transplantation for metabolic deficiencies: decrease of plasms bilirubin in Gunn rats. Science (1976) 1.65
Trauma center maturation: quantification of process and outcome. Ann Surg (1999) 1.64
Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene. J Biol Chem (1994) 1.64
Nitric oxide as a bifunctional regulator of apoptosis. Circ Res (1999) 1.63
Impaired wound healing and angiogenesis in eNOS-deficient mice. Am J Physiol (1999) 1.60
Nitric oxide as a bioregulator of apoptosis. Biochem Biophys Res Commun (2001) 1.57
Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B)-deficient cell line: H4B promotes assembly of enzyme subunits into an active dimer. Proc Natl Acad Sci U S A (1995) 1.56
Comparison of FK-506 and cyclosporine regimens in pediatric renal transplantation. Pediatr Nephrol (1994) 1.55
p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells. Nat Med (1998) 1.55
Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes. Am J Physiol (1991) 1.54
Inhibition of chemotaxis Ng-monomethyl-L-arginine: a role for cyclic GMP. Blood (1989) 1.53
Hemorrhagic shock. Curr Probl Surg (1995) 1.53
The Epstein-Barr virus in the pathogenesis of posttransplant lymphoproliferative disorders. Clinical, pathologic, and virologic correlation. Surgery (1981) 1.53
Inducible nitric oxide synthase and inflammatory diseases. Mol Med (2000) 1.53
Induction of nitric oxide synthase in mouse dendritic cells by IFN-gamma, endotoxin, and interaction with allogeneic T cells: nitric oxide production is associated with dendritic cell apoptosis. J Immunol (1996) 1.53
Mechanisms of microbial synergy in polymicrobial surgical infections. Rev Infect Dis (1985) 1.51
Maltose absorption as an indicator of small-intestinal allograft rejection. J Surg Res (1984) 1.50
Cytokine-induced changes in chromatin structure and in vivo footprints in the inducible NOS promoter. Am J Physiol Lung Cell Mol Physiol (2001) 1.49
Phenotypic characterization of a novel bone marrow-derived cell that facilitates engraftment of allogeneic bone marrow stem cells. Blood (1994) 1.49
Nitric oxide and nitric oxide-generating compounds inhibit hepatocyte protein synthesis. FASEB J (1991) 1.48
The regulatory role of nitric oxide in apoptosis. Int Immunopharmacol (2001) 1.46
Role of anaerobic flora in the translocation of aerobic and facultatively anaerobic intestinal bacteria. Infect Immun (1987) 1.46
Evidence that rat Kupffer cells stimulate and inhibit hepatocyte protein synthesis in vitro by different mechanisms. Gastroenterology (1989) 1.45
Clinical characteristics of the lethal cytomegalovirus infection following renal transplantation. Surgery (1977) 1.45
A controlled trial of interferon with or without prednisone priming for chronic hepatitis B. Gastroenterology (1992) 1.44
Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases. Proc Natl Acad Sci U S A (2000) 1.44
Coagulation disorders in combat casualties. I. Acute changes after wounding. II. Effects of massive transfusion. 3. Post-resuscitative changes. Ann Surg (1969) 1.44
Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-alpha-induced apoptosis and toxicity in the liver. J Med Chem (1997) 1.44
Prostanoid production via COX-2 as a causative mechanism of rodent postoperative ileus. Gastroenterology (2001) 1.44