Deletion of the parasite-specific insertions and mutation of the catalytic triad in glutathione reductase from chloroquine-sensitive Plasmodium falciparum 3D7.

PubWeight™: 0.94‹?›

🔗 View Article (PMID 10779594)

Published in Mol Biochem Parasitol on April 15, 2000

Authors

T W Gilberger1, R H Schirmer, R D Walter, S Müller

Author Affiliations

1: Bernhard Nocht Institute for Tropical Medicine, Biochemical Parasitology, Bernhard-Nocht-Strasse 74, D-20359, Hamburg, Germany.

Articles citing this

Regulation of intracellular glutathione levels in erythrocytes infected with chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum. Biochem J (2002) 1.41

Antioxidant defense in Plasmodium falciparum--data mining of the transcriptome. Malar J (2004) 1.25

Structural and biochemical characterization of a mitochondrial peroxiredoxin from Plasmodium falciparum. Mol Microbiol (2006) 1.14

Glutathione synthetase from Plasmodium falciparum. Biochem J (2002) 0.97

Glutathione reductase-null malaria parasites have normal blood stage growth but arrest during development in the mosquito. J Biol Chem (2010) 0.96

Degrees of chloroquine resistance in Plasmodium - is the redox system involved? Int J Parasitol Drugs Drug Resist (2012) 0.89

Parasite-specific inserts in the bifunctional S-adenosylmethionine decarboxylase/ornithine decarboxylase of Plasmodium falciparum modulate catalytic activities and domain interactions. Biochem J (2004) 0.88

Thioredoxin and glutathione system of malaria parasite Plasmodium falciparum. Protoplasma (2001) 0.86

1,4-naphthoquinones and other NADPH-dependent glutathione reductase-catalyzed redox cyclers as antimalarial agents. Curr Pharm Des (2013) 0.83

Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development. Malar J (2011) 0.81

Binding Isotope Effects for para-Aminobenzoic Acid with Dihydropteroate Synthase from Staphylococcus aureus and Plasmodium falciparum. ACS Chem Biol (2015) 0.75

Articles by these authors

Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature (1995) 7.40

Defective B cell development and function in Btk-deficient mice. Immunity (1995) 4.20

Role of SUMO-1-modified PML in nuclear body formation. Blood (2000) 4.05

Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy. J Exp Med (1996) 3.86

Complete DNA sequence of yeast chromosome XI. Nature (1994) 3.51

The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells. J Cell Biol (2001) 3.43

Cytochromes c1 and b2 are sorted to the intermembrane space of yeast mitochondria by a stop-transfer mechanism. Cell (1992) 3.42

Sp1-mediated transcriptional activation is repressed by Sp3. EMBO J (1994) 3.27

Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes. Nucleic Acids Res (1992) 2.89

Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds. J Biol Chem (1998) 2.72

Substrate positions and induced-fit in crystalline adenylate kinase. J Mol Biol (1977) 2.69

Enzyme inactivation through sulfhydryl oxidation by physiologic NO-carriers. Nat Struct Biol (1998) 2.35

Cytochrome c oxidase assembly in primates is sensitive to small evolutionary variations in amino acid sequence. Mol Biol Evol (2000) 2.19

PIAS/SUMO: new partners in transcriptional regulation. Cell Mol Life Sci (2003) 2.15

The human Rad52 protein exists as a heptameric ring. Curr Biol (2000) 2.09

Degradation of T cell receptor (TCR)-CD3-zeta complexes after antigenic stimulation. J Exp Med (1997) 2.06

Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex. Mol Biol Cell (1995) 2.04

Complete DNA sequence of yeast chromosome II. EMBO J (1994) 1.97

Recovery from Wernicke's aphasia: a positron emission tomographic study. Ann Neurol (1995) 1.86

Antibodies to flagellin indicate reactivity to bacterial antigens in IBS patients. Neurogastroenterol Motil (2008) 1.80

Laufband therapy based on 'rules of spinal locomotion' is effective in spinal cord injured persons. Eur J Neurosci (1995) 1.72

Natural variation in the response of Caenorhabditis elegans towards Bacillus thuringiensis. Parasitology (2004) 1.70

Thioredoxin reductase two modes of catalysis have evolved. Eur J Biochem (2000) 1.70

Laufband locomotion with body weight support improved walking in persons with severe spinal cord injuries. Paraplegia (1992) 1.66

The thioredoxin system of the malaria parasite Plasmodium falciparum. Glutathione reduction revisited. J Biol Chem (2000) 1.63

Thioredoxin reductase as a pathophysiological factor and drug target. Eur J Biochem (2000) 1.63

Effects of staff training on the care of mechanically ventilated patients: a prospective cohort study. Br J Anaesth (2009) 1.63

Glutathione reductase from human erythrocytes. The sequences of the NADPH domain and of the interface domain. Eur J Biochem (1982) 1.63

The structure of the flavoenzyme glutathione reductase. Nature (1978) 1.61

Beam hardening artefacts occur in dental implant scans with the NewTom cone beam CT but not with the dental 4-row multidetector CT. Dentomaxillofac Radiol (2007) 1.58

The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductase from Escherichia coli. Proc Natl Acad Sci U S A (1997) 1.56

Synthetic inhibitors of adenylate kinases in the assays for ATPases and phosphokinases. Eur J Biochem (1975) 1.55

Phosducin is a protein kinase A-regulated G-protein regulator. Nature (1992) 1.55

Internalin B is essential for adhesion and mediates the invasion of Listeria monocytogenes into human endothelial cells. Mol Microbiol (1998) 1.54

Probing the molecular environment of membrane proteins in vivo. Mol Biol Cell (1999) 1.53

Recruitment of spinal motor pools during voluntary movements versus stepping after human spinal cord injury. J Neurotrauma (2002) 1.51

Mental phenomena evoked by electrical stimulation of the human hippocampal formation and amygdala. Brain (1978) 1.47

Topological comparison of adenyl kinase with other proteins. Nature (1974) 1.45

Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes. Curr Biol (2000) 1.45

Mobilization and collection of allogeneic peripheral blood progenitor cells for transplantation. Bone Marrow Transplant (1998) 1.43

Human herpesvirus 6 DNA in exanthematous skin in BMT patient. Lancet (1994) 1.40

MUC1: the polymorphic appearance of a human mucin. Glycobiology (2000) 1.39

Long-term immune reconstitution and outcome after HLA-nonidentical T-cell-depleted bone marrow transplantation for severe combined immunodeficiency: a European retrospective study of 116 patients. Blood (1998) 1.39

Diagnostic factors in adult males following initial seizures. A three-year follow-up. Arch Neurol (1972) 1.36

Brain representation of active and passive movements. Neuroimage (1996) 1.36

Covalent modification of the transcriptional repressor tramtrack by the ubiquitin-related protein Smt3 in Drosophila flies. Mol Cell Biol (2000) 1.36

Characterization of KIF1C, a new kinesin-like protein involved in vesicle transport from the Golgi apparatus to the endoplasmic reticulum. J Biol Chem (1998) 1.35

Regulation of Pax3 transcriptional activity by SUMO-1-modified PML. Oncogene (2001) 1.35

Three-dimensional structure of glutathione reductase at 2 A resolution. J Mol Biol (1981) 1.32

The signal that sorts yeast cytochrome b2 to the mitochondrial intermembrane space contains three distinct functional regions. EMBO J (1993) 1.29

A soluble form of TRAP (CD40 ligand) is rapidly released after T cell activation. Eur J Immunol (1995) 1.29

Initial results in the assessment of multiple myeloma using 18F-FDG PET. Eur J Nucl Med Mol Imaging (2002) 1.28

Maintenance of locomotor abilities following Laufband (treadmill) therapy in para- and tetraplegic persons: follow-up studies. Spinal Cord (1998) 1.27

Arm training induced brain plasticity in stroke studied with serial positron emission tomography. Neuroimage (2001) 1.26

Gene structure, activity and localization of a catalase from intracellular bacteria in Onchocerca volvulus. Mol Biochem Parasitol (1998) 1.25

Inter-domain cross-linking and molecular modelling of the hairpin ribozyme. J Mol Biol (1997) 1.25

Tetrabrachion: a filamentous archaebacterial surface protein assembly of unusual structure and extreme stability. J Mol Biol (1995) 1.24

Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection. Eur J Immunol (1994) 1.23

A hypothesis on the catalytic mechanism of the selenoenzyme thioredoxin reductase. Biochem J (1998) 1.23

Cardio-specific long-term gene expression in a porcine model after selective pressure-regulated retroinfusion of adeno-associated viral (AAV) vectors. Gene Ther (2007) 1.23

Subunit stoichiometry and three-dimensional arrangement in proteasomes from Thermoplasma acidophilum. EMBO J (1992) 1.22

Mammalian cells express two VPS4 proteins both of which are involved in intracellular protein trafficking. J Mol Biol (2001) 1.22

Measurements of all-night sleep in normal elderly persons: effects of aging. J Am Geriatr Soc (1967) 1.22

The thioredoxin system of Plasmodium falciparum and other parasites. Cell Mol Life Sci (2002) 1.22

Trypanothione reductase from Trypanosoma cruzi. Purification and characterization of the crystalline enzyme. Eur J Biochem (1987) 1.21

Evolution of functional reorganization in hemiplegic stroke: a serial positron emission tomographic activation study. Ann Neurol (1999) 1.21

Influence of severe combined immunodeficiency phenotype on the outcome of HLA non-identical, T-cell-depleted bone marrow transplantation: a retrospective European survey from the European group for bone marrow transplantation and the european society for immunodeficiency. J Pediatr (1999) 1.20

1-N-naphthylphthalamic acid and 2,3,5-triiodobenzoic acid : In-vitro binding to particulate cell fractions and action on auxin transport in corn coleoptiles. Planta (1973) 1.19

Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice. Oncogene (2010) 1.19

Identification of stress-responsive genes in Caenorhabditis elegans using RT-PCR differential display. Nucleic Acids Res (1998) 1.19

Structural relationships in the adenylate kinase family. Eur J Biochem (1986) 1.18

[The particularities of contractile proteins of the arteries]. Biochem Z (1965) 1.18

FAD-binding site of glutathione reductase. J Mol Biol (1982) 1.18

Plasmodium falciparum-infected red blood cells depend on a functional glutathione de novo synthesis attributable to an enhanced loss of glutathione. Biochem J (2000) 1.16

The rod domain of NF-L determines neurofilament architecture, whereas the end domains specify filament assembly and network formation. J Cell Biol (1993) 1.16

[What visual information does the automobile driver need for safe driving in street traffic?]. Ophthalmologe (1994) 1.16

Secretion of human meprin from intestinal epithelial cells depends on differential expression of the alpha and beta subunits. Eur J Biochem (1999) 1.15

In the human malaria parasite Plasmodium falciparum, polyamines are synthesized by a bifunctional ornithine decarboxylase, S-adenosylmethionine decarboxylase. J Biol Chem (2000) 1.14

Ubiquitous soluble Mg(2+)-ATPase complex. A structural study. J Mol Biol (1992) 1.13

Folding of the four domains and dimerization are impaired by the Gly446-->Glu exchange in human glutathione reductase. Implications for the design of antiparasitic drugs. Biochemistry (1993) 1.13

Somnambulism: psychophysiological correlates. I. All-night EEG studies. Arch Gen Psychiatry (1966) 1.13

Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates. Eur J Immunol (1996) 1.12

The malaria parasite Plasmodium falciparum possesses a functional thioredoxin system. Mol Biochem Parasitol (2001) 1.12

Mechanisms underlying the anti-inflammatory actions of boswellic acid derivatives in experimental colitis. Am J Physiol Gastrointest Liver Physiol (2006) 1.12

Transcriptional regulation of genes encoding the selenium-free [NiFe]-hydrogenases in the archaeon Methanococcus voltae involves positive and negative control elements. Genetics (1999) 1.12

Changes in peptidergic innervation in chronic pancreatitis. Pancreas (1992) 1.12

The enzymatic synthesis of thiophosphate analogs of nucleotides. Biochim Biophys Acta (1972) 1.11

The [NiFe] hydrogenases of Methanococcus voltae: genes, enzymes and regulation. Arch Microbiol (1997) 1.11

Simultaneous overexpression of enzymes of the lower part of glycolysis can enhance the fermentative capacity of Saccharomyces cerevisiae. Yeast (2000) 1.10

Targeting polyamines of parasitic protozoa in chemotherapy. Trends Parasitol (2001) 1.09

7,8-Dihydropteroate-synthesizing enzyme from Plasmodium chabaudi. Methods Enzymol (1980) 1.08

Functional significance of symmetrical versus asymmetrical GroEL-GroES chaperonin complexes. Science (1995) 1.07

Fluorescent and spin label probes of the environments of the sulfhydryl groups of porcine muscle adenylate kinase. J Biol Chem (1975) 1.07

Recombinant Plasmodium falciparum glutathione reductase is inhibited by the antimalarial dye methylene blue. FEBS Lett (1998) 1.07

Reorganization of sensory and motor systems in hemiplegic stroke patients. A positron emission tomography study. Stroke (1999) 1.07

Laufband (treadmill) therapy in incomplete paraplegia and tetraplegia. J Neurotrauma (1999) 1.06