Published in Nat Struct Biol on April 01, 1998
Nitrosative stress: metabolic pathway involving the flavohemoglobin. Proc Natl Acad Sci U S A (1998) 2.60
Functional site profiling and electrostatic analysis of cysteines modifiable to cysteine sulfenic acid. Protein Sci (2008) 1.54
Oxidative modifications in nitrosative stress. Nat Struct Biol (1998) 1.37
Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme. EMBO J (2001) 1.31
A structurally conserved water molecule in Rossmann dinucleotide-binding domains. Protein Sci (2002) 1.17
Cysteine sulfenic acid as an intermediate in disulfide bond formation and nonenzymatic protein folding. Biochemistry (2010) 1.12
Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin. Biochemistry (2005) 1.09
Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis. J Med Chem (2009) 1.05
Formation, reactivity, and detection of protein sulfenic acids. Chem Res Toxicol (2010) 1.05
Chemical approaches to detect and analyze protein sulfenic acids. Mass Spectrom Rev (2013) 0.96
Evidence for the rapid conversion of stephacidin B into the electrophilic monomer avrainvillamide in cell culture. J Am Chem Soc (2007) 0.96
Zn2+-dependent redox switch in the intracellular T1-T1 interface of a Kv channel. J Biol Chem (2007) 0.96
Decreasing peroxiredoxin II expression decreases glutathione, alters cell cycle distribution, and sensitizes glioma cells to ionizing radiation and H(2)O(2). Free Radic Biol Med (2008) 0.94
Proteomic and mass spectroscopic quantitation of protein S-nitrosation differentiates NO-donors. ACS Chem Biol (2010) 0.94
Comparative transcriptomic and phenotypic analysis of the responses of Bacillus cereus to various disinfectant treatments. Appl Environ Microbiol (2010) 0.93
S-nitrosothiols and the S-nitrosoproteome of the cardiovascular system. Antioxid Redox Signal (2012) 0.93
Linked thioredoxin-glutathione systems in platyhelminth parasites: alternative pathways for glutathione reduction and deglutathionylation. J Biol Chem (2010) 0.91
Thioredoxin reductase and its inhibitors. Curr Protein Pept Sci (2014) 0.89
Possibilities and pitfalls in quantifying the extent of cysteine sulfenic acid modification of specific proteins within complex biofluids. BMC Biochem (2010) 0.89
S-nitrosylation: specificity, occupancy, and interaction with other post-translational modifications. Antioxid Redox Signal (2013) 0.87
Acyl phosphatase activity of NO-inhibited glyceraldehyde-3-phosphate dehydrogenase (GAPDH): a potential mechanism for uncoupling glycolysis from ATP generation in NO-producing cells. Biochem J (1999) 0.85
Targeting the redox balance in inflammatory skin conditions. Int J Mol Sci (2013) 0.84
Reversible inactivation of dihydrolipoamide dehydrogenase by mitochondrial hydrogen peroxide. Free Radic Res (2012) 0.84
Proteomic profiling of nitrosative stress: protein S-oxidation accompanies S-nitrosylation. ACS Chem Biol (2014) 0.83
The impact of nitric oxide toxicity on the evolution of the glutathione transferase superfamily: a proposal for an evolutionary driving force. J Biol Chem (2013) 0.81
Reversible inactivation of dihydrolipoamide dehydrogenase by Angeli's salt. Sheng Wu Wu Li Hsueh Bao (2012) 0.80
Nitrogen monoxide (NO) storage and transport by dinitrosyl-dithiol-iron complexes: long-lived NO that is trafficked by interacting proteins. J Biol Chem (2012) 0.78
An Interplay of S-Nitrosylation and Metal Ion Binding for Astrocytic S100B Protein. PLoS One (2016) 0.75
Improved R-factors for diffraction data analysis in macromolecular crystallography. Nat Struct Biol (1997) 25.74
Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin. J Mol Biol (1993) 11.24
The crystal structure of urease from Klebsiella aerogenes. Science (1995) 4.06
Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain. Cell (2000) 3.94
Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex. Science (1991) 2.83
Crystal structure of the hexameric traffic ATPase of the Helicobacter pylori type IV secretion system. Mol Cell (2000) 2.74
Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds. J Biol Chem (1998) 2.72
Substrate positions and induced-fit in crystalline adenylate kinase. J Mol Biol (1977) 2.69
Typical 2-Cys peroxiredoxins--structures, mechanisms and functions. FEBS J (2009) 2.57
Structure and mechanism of endo/exocellulase E4 from Thermomonospora fusca. Nat Struct Biol (1997) 2.49
Better models by discarding data? Acta Crystallogr D Biol Crystallogr (2013) 2.47
Old yellow enzyme at 2 A resolution: overall structure, ligand binding, and comparison with related flavoproteins. Structure (1994) 1.91
Thioredoxin reductase two modes of catalysis have evolved. Eur J Biochem (2000) 1.70
Roles of the catalytic domain and two cellulose binding domains of Thermomonospora fusca E4 in cellulose hydrolysis. J Bacteriol (1998) 1.65
The thioredoxin system of the malaria parasite Plasmodium falciparum. Glutathione reduction revisited. J Biol Chem (2000) 1.63
Thioredoxin reductase as a pathophysiological factor and drug target. Eur J Biochem (2000) 1.63
Glutathione reductase from human erythrocytes. The sequences of the NADPH domain and of the interface domain. Eur J Biochem (1982) 1.63
Crystal structure of thermostable family 5 endocellulase E1 from Acidothermus cellulolyticus in complex with cellotetraose. Biochemistry (1996) 1.63
Novel fold and putative receptor binding site of granulocyte-macrophage colony-stimulating factor. Science (1991) 1.62
Crystal structure of the catalytic domain of a thermophilic endocellulase. Biochemistry (1993) 1.61
The structure of the flavoenzyme glutathione reductase. Nature (1978) 1.61
The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductase from Escherichia coli. Proc Natl Acad Sci U S A (1997) 1.56
Synthetic inhibitors of adenylate kinases in the assays for ATPases and phosphokinases. Eur J Biochem (1975) 1.55
Refined crystal structure and mutagenesis of human granulocyte-macrophage colony-stimulating factor. Proteins (1996) 1.47
Topological comparison of adenyl kinase with other proteins. Nature (1974) 1.45
Refined structure of porcine cytosolic adenylate kinase at 2.1 A resolution. J Mol Biol (1988) 1.44
Amino acid sequence of spinach ferredoxin:NADP+ oxidoreductase. Biochemistry (1984) 1.41
On the active site of Old Yellow Enzyme. Role of histidine 191 and asparagine 194. J Biol Chem (1998) 1.39
Structural comparisons among the short-chain helical cytokines. Structure (1994) 1.38
Three-dimensional structure of glutathione reductase at 2 A resolution. J Mol Biol (1981) 1.32
AhpF and other NADH:peroxiredoxin oxidoreductases, homologues of low Mr thioredoxin reductase. Eur J Biochem (2000) 1.31
Relatedness of baculovirus and gypsy retrotransposon envelope proteins. BMC Evol Biol (2001) 1.29
A productive NADP+ binding mode of ferredoxin-NADP + reductase revealed by protein engineering and crystallographic studies. Nat Struct Biol (1999) 1.24
A hypothesis on the catalytic mechanism of the selenoenzyme thioredoxin reductase. Biochem J (1998) 1.23
The thioredoxin system of Plasmodium falciparum and other parasites. Cell Mol Life Sci (2002) 1.22
Trypanothione reductase from Trypanosoma cruzi. Purification and characterization of the crystalline enzyme. Eur J Biochem (1987) 1.21
Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease. Biochemistry (1997) 1.21
Preliminary crystallographic studies of urease from jack bean and from Klebsiella aerogenes. J Mol Biol (1992) 1.19
Structural relationships in the adenylate kinase family. Eur J Biochem (1986) 1.18
[The particularities of contractile proteins of the arteries]. Biochem Z (1965) 1.18
Crystallographic analysis of the binding of NADPH, NADPH fragments, and NADPH analogues to glutathione reductase. Biochemistry (1988) 1.18
FAD-binding site of glutathione reductase. J Mol Biol (1982) 1.18
Refined crystal structure of spinach ferredoxin reductase at 1.7 A resolution: oxidized, reduced and 2'-phospho-5'-AMP bound states. J Mol Biol (1995) 1.17
Folding of the four domains and dimerization are impaired by the Gly446-->Glu exchange in human glutathione reductase. Implications for the design of antiparasitic drugs. Biochemistry (1993) 1.13
The enzymatic synthesis of thiophosphate analogs of nucleotides. Biochim Biophys Acta (1972) 1.11
Site-directed mutagenesis improves catalytic efficiency and thermostability of Escherichia coli pH 2.5 acid phosphatase/phytase expressed in Pichia pastoris. Arch Biochem Biophys (2000) 1.11
Structural prototypes for an extended family of flavoprotein reductases: comparison of phthalate dioxygenase reductase with ferredoxin reductase and ferredoxin. Protein Sci (1993) 1.08
Fluorescent and spin label probes of the environments of the sulfhydryl groups of porcine muscle adenylate kinase. J Biol Chem (1975) 1.07
Recombinant Plasmodium falciparum glutathione reductase is inhibited by the antimalarial dye methylene blue. FEBS Lett (1998) 1.07
Glutathione reductase of the malarial parasite Plasmodium falciparum: crystal structure and inhibitor development. J Mol Biol (2003) 1.05
Structure of intact AhpF reveals a mirrored thioredoxin-like active site and implies large domain rotations during catalysis. Biochemistry (2001) 1.04
Structures of the Klebsiella aerogenes urease apoenzyme and two active-site mutants. Biochemistry (1996) 1.01
Glutathione reductase and glutamate dehydrogenase of Plasmodium falciparum, the causative agent of tropical malaria. Eur J Biochem (1996) 0.99
Kinetic and structural characterization of urease active site variants. Biochemistry (2000) 0.99
Cloning and sequencing of mammalian glutathione reductase cDNA. Eur J Biochem (1990) 0.98
Glutathione reductase from human erythrocytes: amino-acid sequence of the structurally known FAD-binding domain. Eur J Biochem (1981) 0.97
Redox processes in malaria and other parasitic diseases. Determination of intracellular glutathione. Histochemistry (1994) 0.97
Trypanothione reductase from Trypanosoma cruzi. Catalytic properties of the enzyme and inhibition studies with trypanocidal compounds. Eur J Biochem (1989) 0.96
Glutathione reductase-deficient erythrocytes as host cells of malarial parasites. Biochem Pharmacol (1988) 0.94
Deletion of the parasite-specific insertions and mutation of the catalytic triad in glutathione reductase from chloroquine-sensitive Plasmodium falciparum 3D7. Mol Biochem Parasitol (2000) 0.94
A prodrug form of a Plasmodium falciparum glutathione reductase inhibitor conjugated with a 4-anilinoquinoline. J Med Chem (2001) 0.94
Glutathione reductase inhibitors as potential antimalarial drugs. Effects of nitrosoureas on Plasmodium falciparum in vitro. Biochem Pharmacol (1988) 0.94
Glutathione reductase from human erythrocytes. Isolation of the enzyme and sequence analysis of the redox-active peptide. Eur J Biochem (1977) 0.92
The bacterial redox signaller pyocyanin as an antiplasmodial agent: comparisons with its thioanalog methylene blue. Redox Rep (2011) 0.91
Probing the roles of active site residues in D-xylose isomerase. J Biol Chem (1995) 0.90
Recombinant putative glutathione reductase of Plasmodium falciparum exhibits thioredoxin reductase activity. Mol Biochem Parasitol (1996) 0.90
Biochemical and crystallographic characterization of ferredoxin-NADP(+) reductase from nonphotosynthetic tissues. Biochemistry (2001) 0.90
Human thioredoxin reductase is efficiently inhibited by (2,2':6',2' '-terpyridine)platinum(II) complexes. Possible implications for a novel antitumor strategy. J Med Chem (2001) 0.90
Kinetics and crystallographic analysis of human glutathione reductase in complex with a xanthene inhibitor. J Biol Chem (1996) 0.90
Study of the active site residues of a glycoside hydrolase family 8 xylanase. J Mol Biol (2005) 0.89
Characterization of metal-substituted Klebsiella aerogenes urease. J Biol Inorg Chem (1999) 0.89
Inhibition of human glutathione reductase by S-nitrosoglutathione. Eur J Biochem (1995) 0.89
Role of active site tyrosine residues in catalysis by human glutathione reductase. Biochemistry (1998) 0.89
Primary and tertiary structure of the principal human adenylate kinase. Eur J Biochem (1976) 0.88
Competition between C-terminal tyrosine and nicotinamide modulates pyridine nucleotide affinity and specificity in plant ferredoxin-NADP(+) reductase. J Biol Chem (2000) 0.88
Charge is the major discriminating factor for glutathione reductase versus trypanothione reductase inhibitors. Bioorg Med Chem (1996) 0.88
Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase. Biochem J (1995) 0.87
Oligosaccharide binding in family 8 glycosidases: crystal structures of active-site mutants of the beta-1,4-xylanase pXyl from Pseudoaltermonas haloplanktis TAH3a in complex with substrate and product. Biochemistry (2006) 0.86
Effects of antioxidants on glutathione levels and clinical recovery from the malnutrition syndrome kwashiorkor--a pilot study. Redox Rep (2005) 0.85
Multimodal treatment of hepatocellular carcinoma (HCC). Onkologie (2004) 0.85
Generating compatible translation initiation regions for heterologous gene expression in Escherichia coli by exhaustive periShine-Dalgarno mutagenesis. Human glutathione reductase cDNA as a model. Nucleic Acids Res (1992) 0.85
1,3-Bis(2-chloroethyl)-1-nitrosourea as thiol-carbamoylating agent in biological systems. Methods Enzymol (1995) 0.85
Kinetic characterization of glutathione reductase from the malarial parasite Plasmodium falciparum. Comparison with the human enzyme. J Biol Chem (2000) 0.85
The structural isomerisation of human-muscle adenylate kinase as studied by 1H-nuclear magnetic resonance. Eur J Biochem (1982) 0.85
Perturbing the metal site in D-xylose isomerase. Effect of mutations of His-220 on enzyme stability. J Biol Chem (1994) 0.85
Dinitrosyl-dithiol-iron complexes, nitric oxide (NO) carriers in vivo, as potent inhibitors of human glutathione reductase and glutathione-S-transferase. Biochem Pharmacol (1997) 0.85
Inhibition of human glutathione reductase by 10-arylisoalloxazines: crystalline, kinetic, and electrochemical studies. J Med Chem (1996) 0.84
The 58 kDa mouse selenoprotein is a BCNU-sensitive thioredoxin reductase. FEBS Lett (1997) 0.84
Mitochondrial adenylate kinase (AK2) from bovine heart. Homology with the cytosolic isoenzyme in the catalytic region. Eur J Biochem (1984) 0.84
Denaturation and reactivation of dimeric human glutathione reductase--an assay for folding inhibitors. Eur J Biochem (1997) 0.84
'Fast-track' colonic surgery in Austria and Germany--results from the survey on patterns in current perioperative practice. Colorectal Dis (2008) 0.83
Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand. Biochemistry (1998) 0.83
Crystal structures of two mutants that have implications for the folding of bovine pancreatic ribonuclease A. Protein Sci (1998) 0.83
Expression of selenium-containing proteins in human colon carcinoma tissue. Anticancer Res (2011) 0.83
Flavin analogs with antimalarial activity as glutathione reductase inhibitors. Biochem Pharmacol (1990) 0.83
Hematopoietic growth factors: understanding functional diversity in structural terms. Blood (1993) 0.83