Published in J Biol Chem on May 05, 2000
Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coli. Genetics (2001) 6.29
PerR controls oxidative stress resistance and iron storage proteins and is required for virulence in Staphylococcus aureus. Infect Immun (2001) 2.57
Essential thioredoxin-dependent peroxiredoxin system from Helicobacter pylori: genetic and kinetic characterization. J Bacteriol (2001) 1.85
Transcriptome analysis of the response of Pseudomonas aeruginosa to hydrogen peroxide. J Bacteriol (2004) 1.71
Differential gene expression in response to hydrogen peroxide and the putative PerR regulon of Synechocystis sp. strain PCC 6803. J Bacteriol (2004) 1.64
Catalytic mechanism of thiol peroxidase from Escherichia coli. Sulfenic acid formation and overoxidation of essential CYS61. J Biol Chem (2003) 1.61
Interactions of glutaredoxins, ribonucleotide reductase, and components of the DNA replication system of Escherichia coli. Proc Natl Acad Sci U S A (2004) 1.33
Transcriptome analysis of Escherichia coli O157:H7 exposed to lysates of lettuce leaves. Appl Environ Microbiol (2010) 1.29
mRNA expression profiles for Escherichia coli ingested by normal and phagocyte oxidase-deficient human neutrophils. J Clin Invest (2002) 1.27
NrdR controls differential expression of the Escherichia coli ribonucleotide reductase genes. J Bacteriol (2007) 1.23
Modulation of glutaredoxin in the lung and sputum of cigarette smokers and chronic obstructive pulmonary disease. Respir Res (2006) 1.22
Hydrogen peroxide activates the SoxRS regulon in vivo. J Bacteriol (2000) 1.18
Thioredoxin reductase is a key factor in the oxidative stress response of Lactobacillus plantarum WCFS1. Microb Cell Fact (2007) 1.17
Molecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for Mammalian s phase ribonucleotide reductase. J Biol Chem (2009) 1.16
The glutaredoxin family in oxygenic photosynthetic organisms. Photosynth Res (2004) 1.12
Genome-wide transcriptional profiling of the steady-state response of Pseudomonas aeruginosa to hydrogen peroxide. J Bacteriol (2005) 1.10
Involvement of superoxide dismutases in the response of Escherichia coli to selenium oxides. J Bacteriol (2002) 1.09
Exogenous glutathione completes the defense against oxidative stress in Haemophilus influenzae. J Bacteriol (2003) 1.08
DNA repair and genome maintenance in Bacillus subtilis. Microbiol Mol Biol Rev (2012) 1.03
KatG is the primary detoxifier of hydrogen peroxide produced by aerobic metabolism in Bradyrhizobium japonicum. J Bacteriol (2004) 1.02
Heme-dependent metalloregulation by the iron response regulator (Irr) protein in Rhizobium and other Alpha-proteobacteria. Biometals (2008) 0.99
The glutathione-glutaredoxin system in Rhodobacter capsulatus: part of a complex regulatory network controlling defense against oxidative stress. J Bacteriol (2004) 0.95
FNR-mediated oxygen-responsive regulation of the nrdDG operon of Escherichia coli. J Bacteriol (2003) 0.92
SoxRS down-regulation of rob transcription. J Bacteriol (2002) 0.90
The thioredoxin superfamily in Chlamydomonas reinhardtii. Photosynth Res (2004) 0.89
Global analysis of gene expression in NGF-deprived sympathetic neurons identifies molecular pathways associated with cell death. BMC Genomics (2011) 0.89
The logic of kinetic regulation in the thioredoxin system. BMC Syst Biol (2011) 0.89
Two new Sinorhizobium meliloti LysR-type transcriptional regulators required for nodulation. J Bacteriol (2005) 0.86
Cytosolic, mitochondrial thioredoxins and thioredoxin reductases in Arabidopsis thaliana. Photosynth Res (2004) 0.83
Physiological adaptation of the bacterium Lactococcus lactis in response to the production of human CFTR. Mol Cell Proteomics (2011) 0.81
Mechanisms of the beneficial actions of ischemic preconditioning on subcellular remodeling in ischemic-reperfused heart. Curr Cardiol Rev (2010) 0.80
Salmonella enterica serovar typhimurium trxA mutants are protective against virulent challenge and induce less inflammation than the live-attenuated vaccine strain SL3261. Infect Immun (2009) 0.80
YjcC, a c-di-GMP phosphodiesterase protein, regulates the oxidative stress response and virulence of Klebsiella pneumoniae CG43. PLoS One (2013) 0.79
Mutations at several loci cause increased expression of ribonucleotide reductase in Escherichia coli. J Bacteriol (2012) 0.79
The SOS Regulatory Network. Ecosal Plus (2008) 0.79
Cell growth of wall-free L-form bacteria is limited by oxidative damage. Curr Biol (2015) 0.78
Thioredoxin. Annu Rev Biochem (1985) 9.82
Physiological functions of thioredoxin and thioredoxin reductase. Eur J Biochem (2000) 7.25
Thioredoxin catalyzes the reduction of insulin disulfides by dithiothreitol and dihydrolipoamide. J Biol Chem (1979) 5.02
The role of the thioredoxin and glutaredoxin pathways in reducing protein disulfide bonds in the Escherichia coli cytoplasm. J Biol Chem (1997) 3.42
Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors. Proc Natl Acad Sci U S A (2005) 3.20
Rat liver thioredoxin and thioredoxin reductase: purification and characterization. Biochemistry (1982) 2.93
Bronchial hyperreactivity to prostaglandin F 2 and histamine in patients with asthma. Br Med J (1973) 2.65
Three-dimensional structure of Escherichia coli thioredoxin-S2 to 2.8 A resolution. Proc Natl Acad Sci U S A (1975) 2.53
Hydrogen donor system for Escherichia coli ribonucleoside-diphosphate reductase dependent upon glutathione. Proc Natl Acad Sci U S A (1976) 2.52
Redox potentials of glutaredoxins and other thiol-disulfide oxidoreductases of the thioredoxin superfamily determined by direct protein-protein redox equilibria. J Biol Chem (1997) 2.33
Reduction of disulfides by thioredoxin. Exceptional reactivity of insulin and suggested functions of thioredoxin in mechanism of hormone action. J Biol Chem (1979) 2.31
Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations. J Biol Chem (2000) 2.26
Thioredoxin. 6. The amino acid sequence of the protein from escherichia coli B. Eur J Biochem (1968) 2.23
Preparation and assay of mammalian thioredoxin and thioredoxin reductase. Methods Enzymol (1999) 2.15
Differential reactivity of the functional sulfhydryl groups of cysteine-32 and cysteine-35 present in the reduced form of thioredoxin from Escherichia coli. J Biol Chem (1980) 2.15
Structural and functional relations among thioredoxins of different species. Proteins (1991) 2.05
Hypersensitivity and desensitization to antineoplastic agents: outcomes of 189 procedures with a new short protocol and novel diagnostic tools assessment. Allergy (2013) 2.00
Mimicking the active site of protein disulfide-isomerase by substitution of proline 34 in Escherichia coli thioredoxin. J Biol Chem (1991) 1.92
Structure and mechanism of mammalian thioredoxin reductase: the active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequence. Proc Natl Acad Sci U S A (2000) 1.89
S-nitrosoglutathione is cleaved by the thioredoxin system with liberation of glutathione and redox regulating nitric oxide. J Biol Chem (1996) 1.84
Thioredoxin, a redox enzyme released in infection and inflammation, is a unique chemoattractant for neutrophils, monocytes, and T cells. J Exp Med (1999) 1.84
Bovine thioredoxin system. Purification of thioredoxin reductase from calf liver and thymus and studies of its function in disulfide reduction. J Biol Chem (1977) 1.80
Three-dimensional structure of a mammalian thioredoxin reductase: implications for mechanism and evolution of a selenocysteine-dependent enzyme. Proc Natl Acad Sci U S A (2001) 1.80
High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin. Structure (1994) 1.79
Two additional glutaredoxins exist in Escherichia coli: glutaredoxin 3 is a hydrogen donor for ribonucleotide reductase in a thioredoxin/glutaredoxin 1 double mutant. Proc Natl Acad Sci U S A (1994) 1.77
Glutathione-dependent synthesis of deoxyribonucleotides. Characterization of the enzymatic mechanism of Escherichia coli glutaredoxin. J Biol Chem (1979) 1.69
Characterization of Escherichia coli NrdH. A glutaredoxin-like protein with a thioredoxin-like activity profile. J Biol Chem (1997) 1.69
Effects of buried charged groups on cysteine thiol ionization and reactivity in Escherichia coli thioredoxin: structural and functional characterization of mutants of Asp 26 and Lys 57. Biochemistry (1997) 1.67
1-Chloro-2,4-dinitrobenzene is an irreversible inhibitor of human thioredoxin reductase. Loss of thioredoxin disulfide reductase activity is accompanied by a large increase in NADPH oxidase activity. J Biol Chem (1995) 1.64
Cloning and expression of a novel human glutaredoxin (Grx2) with mitochondrial and nuclear isoforms. J Biol Chem (2001) 1.63
Structural and functional characterization of the mutant Escherichia coli glutaredoxin (C14----S) and its mixed disulfide with glutathione. Biochemistry (1992) 1.56
Tryptophan fluorescence study of conformational transitions of the oxidized and reduced form of thioredoxin. J Biol Chem (1972) 1.52
Protein disulfide-isomerase is a substrate for thioredoxin reductase and has thioredoxin-like activity. J Biol Chem (1990) 1.51
Determination of the reduction-oxidation potential of the thioredoxin-like domains of protein disulfide-isomerase from the equilibrium with glutathione and thioredoxin. Biochemistry (1993) 1.49
Expression analysis of the nrdHIEF operon from Escherichia coli. Conditions that trigger the transcript level in vivo. J Biol Chem (2001) 1.49
Glutathione-dependent synthesis of deoxyribonucleotides. Purification and characterization of glutaredoxin from Escherichia coli. J Biol Chem (1979) 1.47
Mycobacterium chelonei iatrogenic infections. J Clin Microbiol (1978) 1.46
Three-dimensional solution structure of the reduced form of Escherichia coli thioredoxin determined by nuclear magnetic resonance spectroscopy. Biochemistry (1990) 1.46
Human thioredoxin reductase directly reduces lipid hydroperoxides by NADPH and selenocystine strongly stimulates the reaction via catalytically generated selenols. J Biol Chem (1995) 1.45
Conformational and functional similarities between glutaredoxin and thioredoxins. EMBO J (1984) 1.44
A Pro to His mutation in active site of thioredoxin increases its disulfide-isomerase activity 10-fold. New refolding systems for reduced or randomly oxidized ribonuclease. J Biol Chem (1992) 1.44
Rat and calf thioredoxin reductase are homologous to glutathione reductase with a carboxyl-terminal elongation containing a conserved catalytically active penultimate selenocysteine residue. J Biol Chem (1998) 1.42
The thioredoxin and glutaredoxin systems are efficient electron donors to human plasma glutathione peroxidase. J Biol Chem (1994) 1.40
Isolation and characterization of calf liver thioredoxin. J Biol Chem (1974) 1.39
In vivo transcription of the Escherichia coli oxyR regulon as a function of growth phase and in response to oxidative stress. J Bacteriol (1999) 1.38
Thioredoxin or glutaredoxin in Escherichia coli is essential for sulfate reduction but not for deoxyribonucleotide synthesis. J Bacteriol (1990) 1.35
Thiroedoxin from Escherichia coli. Radioimmunological and enzymatic determinations in wild type cells and mutants defective in phage T7 DNA replication. J Biol Chem (1978) 1.35
Thioredoxin 2: cleavage with cyanogen bromide. Eur J Biochem (1967) 1.34
Selenite is a substrate for calf thymus thioredoxin reductase and thioredoxin and elicits a large non-stoichiometric oxidation of NADPH in the presence of oxygen. Eur J Biochem (1992) 1.31
Analysis of the inhibition of mammalian thioredoxin, thioredoxin reductase, and glutaredoxin by cis-diamminedichloroplatinum (II) and its major metabolite, the glutathione-platinum complex. Free Radic Biol Med (2001) 1.30
Enzymatic reduction-oxidation of protein disulfides by thioredoxin. Methods Enzymol (1984) 1.29
Cloning, overexpression, and characterization of glutaredoxin 2, an atypical glutaredoxin from Escherichia coli. J Biol Chem (1997) 1.28
Proof that the endogenous, heat-stable glucocorticoid receptor-activating factor is thioredoxin. J Biol Chem (1985) 1.25
Proton sharing between cysteine thiols in Escherichia coli thioredoxin: implications for the mechanism of protein disulfide reduction. Biochemistry (1995) 1.25
Reactivity of glutaredoxins 1, 2, and 3 from Escherichia coli shows that glutaredoxin 2 is the primary hydrogen donor to ArsC-catalyzed arsenate reduction. J Biol Chem (1999) 1.25
The primary structure of Escherichia coli glutaredoxin. Distant homology with thioredoxins in a superfamily of small proteins with a redox-active cystine disulfide/cysteine dithiol. Eur J Biochem (1983) 1.23
Thioredoxin and related proteins in procaryotes. FEMS Microbiol Rev (1988) 1.23
Tissue distrubution and subcellular localization of bovine thioredoxin determined by radioimmunoassay. Biochemistry (1978) 1.21
Regulation of ribonucleotide reductase. Curr Top Cell Regul (1981) 1.21
Glutathione-dependent hydrogen donor system for calf thymus ribonucleoside-diphosphate reductase. Proc Natl Acad Sci U S A (1979) 1.21
The in vivo distribution of oxidized and reduced thioredoxin in Escherichia coli. J Biol Chem (1982) 1.20
Mutagenesis of structural half-cystine residues in human thioredoxin and effects on the regulation of activity by selenodiglutathione. Biochemistry (1993) 1.20
Mammalian thioredoxin reductase is irreversibly inhibited by dinitrohalobenzenes by alkylation of both the redox active selenocysteine and its neighboring cysteine residue. J Biol Chem (1998) 1.20
Widespread expression of thioredoxin and thioredoxin reductase in non-small cell lung carcinoma. Clin Cancer Res (2001) 1.20
Selenodiglutathione is a highly efficient oxidant of reduced thioredoxin and a substrate for mammalian thioredoxin reductase. J Biol Chem (1992) 1.19
Efficient reduction of lipoamide and lipoic acid by mammalian thioredoxin reductase. Biochem Biophys Res Commun (1996) 1.18
Reconstitution of Escherichia coli thioredoxin from complementing peptide fragments obtained by cleavage at methionine-37 or arginine-73. J Biol Chem (1975) 1.18
Immunochemistry of thioredoxin. I. Preparation and cross-reactivity of antibodies against thioredoxin from Escherichia coli and bacteriophage T4. J Biol Chem (1972) 1.18
Hydrogen peroxide activates the SoxRS regulon in vivo. J Bacteriol (2000) 1.18
Studies on the structure of T4 thioredoxin. II. Amino acid sequence of the protein and comparison with thioredoxin from Escherichia coli. J Biol Chem (1972) 1.16
Picosecond tryptophan fluorescence of thioredoxin: evidence for discrete species in slow exchange. Biochemistry (1989) 1.16
Thioredoxin. A localized conformational change accompanying reduction of the protein to the sulfhydryl form. Biochemistry (1967) 1.16
The levels of ribonucleotide reductase, thioredoxin, glutaredoxin 1, and GSH are balanced in Escherichia coli K12. J Biol Chem (1996) 1.15
New thioredoxins and glutaredoxins as electron donors of 3'-phosphoadenylylsulfate reductase. J Biol Chem (1999) 1.15
Immunohistochemical localization of thioredoxin and thioredoxin reductase in adult rats. Eur J Cell Biol (1985) 1.15
Glutaredoxin from calf thymus. Purification to homogeneity. J Biol Chem (1982) 1.14
In vivo transcription of nrdAB operon and of grxA and fpg genes is triggered in Escherichia coli lacking both thioredoxin and glutaredoxin 1 or thioredoxin and glutathione, respectively. J Biol Chem (1998) 1.13
Possible involvement of thioredoxin reductase as well as thioredoxin in cellular sensitivity to cis-diamminedichloroplatinum (II). Free Radic Biol Med (1999) 1.13
Electric chips for rapid detection and quantification of nucleic acids. Biosens Bioelectron (2004) 1.12
Construction and characterization of glutaredoxin-negative mutants of Escherichia coli. Proc Natl Acad Sci U S A (1988) 1.11
Reduction of purothionin by the wheat seed thioredoxin system. Plant Physiol (1987) 1.11
A conformational study of thioredoxin and its tryptic fragments. J Biol Chem (1981) 1.11
Sequence-specific 1H n.m.r. assignments and determination of the three-dimensional structure of reduced Escherichia coli glutaredoxin. J Mol Biol (1991) 1.11
Calcium-binding properties of bovine factor X lacking the gamma-carboxyglutamic acid-containing region. J Biol Chem (1984) 1.11
NMR structure of Escherichia coli glutaredoxin 3-glutathione mixed disulfide complex: implications for the enzymatic mechanism. J Mol Biol (1999) 1.11
Chronic elevation of plasma thioredoxin: inhibition of chemotaxis and curtailment of life expectancy in AIDS. Proc Natl Acad Sci U S A (2001) 1.11
Measurement of thioredoxin and thioredoxin reductase. Curr Protoc Toxicol (2001) 1.11
Immunoelectron microscopic localization of glutaredoxin and thioredoxin in Escherichia coli cells. FEBS Lett (1981) 1.10
Enzymatic synthesis of deoxyribonucleotides, 8. The effects of ATP and dATP in the CDP reductase system from E. coli. Proc Natl Acad Sci U S A (1965) 1.10
Substitution of the conserved tryptophan 31 in Escherichia coli thioredoxin by site-directed mutagenesis and structure-function analysis. J Biol Chem (1991) 1.10
Selenium and the thioredoxin and glutaredoxin systems. Biomed Environ Sci (1997) 1.10
Comparison of backbone and tryptophan side-chain dynamics of reduced and oxidized Escherichia coli thioredoxin using 15N NMR relaxation measurements. Biochemistry (1993) 1.09
Solution structure of Escherichia coli glutaredoxin-2 shows similarity to mammalian glutathione-S-transferases. J Mol Biol (2001) 1.09
Measurements of plasma glutaredoxin and thioredoxin in healthy volunteers and during open-heart surgery. Free Radic Biol Med (1998) 1.09