Published in Genetics on May 01, 2000
Signal transduction cascades regulating fungal development and virulence. Microbiol Mol Biol Rev (2000) 5.49
Engineered control of cell morphology in vivo reveals distinct roles for yeast and filamentous forms of Candida albicans during infection. Eukaryot Cell (2003) 4.71
Critical role of Bcr1-dependent adhesins in C. albicans biofilm formation in vitro and in vivo. PLoS Pathog (2006) 3.58
NRG1 represses yeast-hypha morphogenesis and hypha-specific gene expression in Candida albicans. EMBO J (2001) 3.48
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NRG1, a repressor of filamentous growth in C.albicans, is down-regulated during filament induction. EMBO J (2001) 2.76
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Discovering the secrets of the Candida albicans agglutinin-like sequence (ALS) gene family--a sticky pursuit. Med Mycol (2008) 2.46
Rfg1, a protein related to the Saccharomyces cerevisiae hypoxic regulator Rox1, controls filamentous growth and virulence in Candida albicans. Mol Cell Biol (2001) 2.22
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Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol (2005) 2.09
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Protein kinase A operates a molecular switch that governs yeast pseudohyphal differentiation. Mol Cell Biol (2002) 1.84
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Candidalysin is a fungal peptide toxin critical for mucosal infection. Nature (2016) 1.76
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Farnesol and dodecanol effects on the Candida albicans Ras1-cAMP signalling pathway and the regulation of morphogenesis. Mol Microbiol (2008) 1.61
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The protein kinase Tor1 regulates adhesin gene expression in Candida albicans. PLoS Pathog (2009) 1.44
Global roles of Ssn6 in Tup1- and Nrg1-dependent gene regulation in the fungal pathogen, Candida albicans. Mol Biol Cell (2005) 1.42
Candida albicans Hap43 is a repressor induced under low-iron conditions and is essential for iron-responsive transcriptional regulation and virulence. Eukaryot Cell (2010) 1.42
Gpr1, a putative G-protein-coupled receptor, regulates morphogenesis and hypha formation in the pathogenic fungus Candida albicans. Eukaryot Cell (2004) 1.40
The DNA binding protein Rfg1 is a repressor of filamentation in Candida albicans. Genetics (2001) 1.39
The Hos2 Histone Deacetylase Controls Ustilago maydis Virulence through Direct Regulation of Mating-Type Genes. PLoS Pathog (2015) 1.38
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Inhibition of filamentation can be used to treat disseminated candidiasis. Antimicrob Agents Chemother (2006) 1.32
Adaptations of Candida albicans for growth in the mammalian intestinal tract. Eukaryot Cell (2010) 1.32
Contribution of Candida albicans ALS1 to the pathogenesis of experimental oropharyngeal candidiasis. Infect Immun (2002) 1.30
Efg1, a morphogenetic regulator in Candida albicans, is a sequence-specific DNA binding protein. J Bacteriol (2001) 1.24
The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans. PLoS Pathog (2010) 1.16
Candida albicans VPS1 contributes to protease secretion, filamentation, and biofilm formation. Fungal Genet Biol (2008) 1.14
Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction. Eukaryot Cell (2008) 1.12
Small-molecule inhibitors of the budded-to-hyphal-form transition in the pathogenic yeast Candida albicans. Antimicrob Agents Chemother (2005) 1.09
Candida albicans INT1-induced filamentation in Saccharomyces cerevisiae depends on Sla2p. Mol Cell Biol (2001) 1.08
Normal adaptation of Candida albicans to the murine gastrointestinal tract requires Efg1p-dependent regulation of metabolic and host defense genes. Eukaryot Cell (2012) 1.06
Ciclopirox olamine treatment affects the expression pattern of Candida albicans genes encoding virulence factors, iron metabolism proteins, and drug resistance factors. Antimicrob Agents Chemother (2003) 1.06
Aspergillus fumigatus AcuM regulates both iron acquisition and gluconeogenesis. Mol Microbiol (2010) 1.04
Spt3 plays opposite roles in filamentous growth in Saccharomyces cerevisiae and Candida albicans and is required for C. albicans virulence. Genetics (2002) 1.04
Candidiasis drug discovery and development: new approaches targeting virulence for discovering and identifying new drugs. Expert Opin Drug Discov (2013) 1.03
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Calcineurin plays key roles in the dimorphic transition and virulence of the human pathogenic zygomycete Mucor circinelloides. PLoS Pathog (2013) 1.02
Roles of TUP1 in switching, phase maintenance, and phase-specific gene expression in Candida albicans. Eukaryot Cell (2002) 1.01
RBR1, a novel pH-regulated cell wall gene of Candida albicans, is repressed by RIM101 and activated by NRG1. Eukaryot Cell (2004) 1.00
The Candida albicans-specific gene EED1 encodes a key regulator of hyphal extension. PLoS One (2011) 1.00
The Golgi GDPase of the fungal pathogen Candida albicans affects morphogenesis, glycosylation, and cell wall properties. Eukaryot Cell (2002) 0.99
A core filamentation response network in Candida albicans is restricted to eight genes. PLoS One (2013) 0.99
Ash1 protein, an asymmetrically localized transcriptional regulator, controls filamentous growth and virulence of Candida albicans. Mol Cell Biol (2002) 0.99
Candida albicans RFX2 encodes a DNA binding protein involved in DNA damage responses, morphogenesis, and virulence. Eukaryot Cell (2009) 0.99
Candida albicans Sfl1 suppresses flocculation and filamentation. Eukaryot Cell (2007) 0.98
Cdc42p GTPase regulates the budded-to-hyphal-form transition and expression of hypha-specific transcripts in Candida albicans. Eukaryot Cell (2004) 0.98
Candida albicans white and opaque cells undergo distinct programs of filamentous growth. PLoS Pathog (2013) 0.98
A large-scale complex haploinsufficiency-based genetic interaction screen in Candida albicans: analysis of the RAM network during morphogenesis. PLoS Genet (2011) 0.97
C. albicans increases cell wall mannoprotein, but not mannan, in response to blood, serum and cultivation at physiological temperature. Glycobiology (2011) 0.97
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Comparative phenotypic analysis of the major fungal pathogens Candida parapsilosis and Candida albicans. PLoS Pathog (2014) 0.96
The Ess1 prolyl isomerase is required for growth and morphogenetic switching in Candida albicans. Genetics (2002) 0.96
Heterogeneous distribution of Candida albicans cell-surface antigens demonstrated with an Als1-specific monoclonal antibody. Microbiology (2010) 0.96
Gpa2, a G-protein alpha subunit required for hyphal development in Candida albicans. Eukaryot Cell (2002) 0.94
A 368-base-pair cis-acting HWP1 promoter region, HCR, of Candida albicans confers hypha-specific gene regulation and binds architectural transcription factors Nhp6 and Gcf1p. Eukaryot Cell (2007) 0.93
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Conjugated linoleic acid inhibits hyphal growth in Candida albicans by modulating Ras1p cellular levels and downregulating TEC1 expression. Eukaryot Cell (2011) 0.92
The general transcriptional repressor Tup1 is required for dimorphism and virulence in a fungal plant pathogen. PLoS Pathog (2011) 0.91
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N-acetylglucosamine kinase, HXK1 is involved in morphogenetic transition and metabolic gene expression in Candida albicans. PLoS One (2013) 0.89
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In vitro and in vivo activities of pterostilbene against Candida albicans biofilms. Antimicrob Agents Chemother (2014) 0.88
Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host-pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides. Mol Microbiol (2015) 0.88
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The non-receptor tyrosine kinase Tec controls assembly and activity of the noncanonical caspase-8 inflammasome. PLoS Pathog (2014) 0.86
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