Dendritic cells at a DNA vaccination site express the encoded influenza nucleoprotein and prime MHC class I-restricted cytolytic lymphocytes upon adoptive transfer.

PubWeight™: 0.82‹?›

🔗 View Article (PMID 10837410)

Published in Int Immunol on June 01, 2000

Authors

A Bot1, A C Stan, K Inaba, R Steinman, C Bona

Author Affiliations

1: Department of Microbiology, Mount Sinai School of Medicine, New York, NY 10029, USA.

Articles by these authors

Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med (2001) 9.70

The induction of tolerance by dendritic cells that have captured apoptotic cells. J Exp Med (2000) 5.74

Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells. J Exp Med (1989) 5.65

Dendritic cells exposed to human immunodeficiency virus type-1 transmit a vigorous cytopathic infection to CD4+ T cells. Science (1992) 5.61

Resting and sensitized T lymphocytes exhibit distinct stimulatory (antigen-presenting cell) requirements for growth and lymphokine release. J Exp Med (1984) 5.54

Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo. Immunity (1999) 5.23

Developmental regulation of MHC class II transport in mouse dendritic cells. Nature (1997) 5.17

The cell surface of mouse dendritic cells: FACS analyses of dendritic cells from different tissues including thymus. Cell Immunol (1989) 4.96

Dendritic cells in the T-cell areas of lymphoid organs. Immunol Rev (1997) 4.41

Oligomeric structure of gp41, the transmembrane protein of human immunodeficiency virus type 1. J Virol (1989) 4.07

Defining criteria for autoimmune diseases (Witebsky's postulates revisited) Immunol Today (1993) 3.81

Immunologic properties of purified epidermal Langerhans cells. Distinct requirements for stimulation of unprimed and sensitized T lymphocytes. J Exp Med (1986) 3.74

Dendritic cells are critical accessory cells for thymus-dependent antibody responses in mouse and in man. Proc Natl Acad Sci U S A (1983) 3.25

Clustering of dendritic cells, helper T lymphocytes, and histocompatible B cells during primary antibody responses in vitro. J Exp Med (1984) 3.23

Immune and clinical responses in patients with metastatic melanoma to CD34(+) progenitor-derived dendritic cell vaccine. Cancer Res (2001) 3.01

Interleukin 1 enhances T-dependent immune responses by amplifying the function of dendritic cells. J Exp Med (1987) 2.97

Direct activation of CD8+ cytotoxic T lymphocytes by dendritic cells. J Exp Med (1987) 2.94

Transport of peptide-MHC class II complexes in developing dendritic cells. Science (2000) 2.62

Defective gamma interferon production in leprosy. Reversal with antigen and interleukin 2. J Exp Med (1983) 2.61

Protein-specific helper T-lymphocyte formation initiated by dendritic cells. Science (1985) 2.55

Dendritic cells are the principal cells in mouse spleen bearing immunogenic fragments of foreign proteins. J Exp Med (1990) 2.54

Cellular basis of regulation of expression of idiotype. I. T-suppressor cells specific for MOPC 460 idiotype regulate the expression of cells secreting anti-TNP antibodies bearing 460 idiotype. J Exp Med (1979) 2.53

Accessory cell-T lymphocyte interactions. Antigen-dependent and -independent clustering. J Exp Med (1986) 2.47

Dendritic cells induce T lymphocytes to release B cell-stimulating factors by an interleukin 2-dependent mechanism. J Exp Med (1983) 2.42

Antigen processing by epidermal Langerhans cells correlates with the level of biosynthesis of major histocompatibility complex class II molecules and expression of invariant chain. J Exp Med (1990) 2.39

Stimulation of lymphokine release from T lymphoblasts. Requirement for mRNA synthesis and inhibition by cyclosporin A. J Exp Med (1984) 2.24

Mitogenic effect of bacterial peptidoglycans possessing adjuvant activity. J Immunol (1975) 2.15

Identification of macrophages and dendritic cells in the osteopetrotic (op/op) mouse. J Cell Sci (1993) 2.15

Macrophage factors which enhance the mixed leukocyte reaction initiated by dendritic cells. J Immunol (1989) 2.08

Use of the fluorescence activated cell sorter to enrich dendritic cells from mouse spleen. J Immunol Methods (1990) 2.04

Differential regulation of human blood dendritic cell subsets by IFNs. J Immunol (2001) 2.02

Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. II. Expression in situ in lymphoid and nonlymphoid tissues. Cell Immunol (1995) 1.99

Presentation of a viral T cell epitope expressed in the CDR3 region of a self immunoglobulin molecule. Science (1993) 1.96

Properties of memory T lymphocytes isolated from the mixed leukocyte reaction. Proc Natl Acad Sci U S A (1985) 1.92

Influenza A virus transfectants with chimeric hemagglutinins containing epitopes from different subtypes. J Virol (1992) 1.88

Systematic review and meta-analysis of the diagnostic and therapeutic role of water-soluble contrast agent in adhesive small bowel obstruction. Br J Surg (2010) 1.86

Dendritic cells as adjuvants for class I major histocompatibility complex-restricted antitumor immunity. J Exp Med (1996) 1.83

Fractalkine and macrophage-derived chemokine: T cell-attracting chemokines expressed in T cell area dendritic cells. Eur J Immunol (1999) 1.82

Distinct mechanisms of neonatal tolerance induced by dendritic cells and thymic B cells. J Exp Med (1991) 1.82

Cellular basis of regulation of expression of idiotype. II. Immunity to anti-MOPC-460 idiotype antibodies increases the level of anti-trinitrophenyl antibodies bearing 460 idiotypes. J Exp Med (1979) 1.76

Monoclonal antibodies to LFA-1 and to CD4 inhibit the mixed leukocyte reaction after the antigen-dependent clustering of dendritic cells and T lymphocytes. J Exp Med (1987) 1.76

Five mouse homologues of the human dendritic cell C-type lectin, DC-SIGN. Int Immunol (2001) 1.74

Chimeric influenza virus induces neutralizing antibodies and cytotoxic T cells against human immunodeficiency virus type 1. J Virol (1993) 1.70

Skin antigens in the steady state are trafficked to regional lymph nodes by transforming growth factor-beta1-dependent cells. Int Immunol (2001) 1.68

Blastic transformtion of mouse spleen lymphocytes by a water-soluble mitogen extracted from Nocardia. Proc Natl Acad Sci U S A (1974) 1.62

Antigen capture, processing, and presentation by dendritic cells: recent cell biological studies. Hum Immunol (1999) 1.57

Immune response to levan. I. Kinetics and ontogeny of anti-levan and anti-inulin antibody response and of expression of cross-reactive idiotype. J Immunol (1978) 1.57

A CD1a+/CD11c+ subset of human blood dendritic cells is a direct precursor of Langerhans cells. J Immunol (1999) 1.57

Proteases as mitogens. The Effect of trypsin and pronase on mouse and human lymphocytes. Exp Cell Res (1974) 1.56

Contrasting effect of alpha/beta- and gamma-interferons on expression of macrophage Ia antigens. J Exp Med (1986) 1.55

Isolation of mitogenic and adjuvant active fractions from various species of Nocardiae. Infect Immun (1975) 1.54

Antigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II-restricted viral epitope. J Exp Med (1997) 1.53

The Chlamydomonas reinhardtii ODA3 gene encodes a protein of the outer dynein arm docking complex. J Cell Biol (1997) 1.53

EBNA1-specific CD4+ T cells in healthy carriers of Epstein-Barr virus are primarily Th1 in function. J Clin Invest (2001) 1.53

Unusual phenotype of B cells in the thymus of normal mice. J Exp Med (1988) 1.51

New method for obliterative treatment of an anterior wall aneurysm in the internal carotid artery: encircling silicone sheet clip procedure--technical case report. Neurosurgery (2001) 1.47

Identification of a new V kappa gene family that is highly expressed in hybridomas from an autoimmune mouse strain. J Immunol (1990) 1.46

Conditions that induce tolerance in mature CD4+ T cells. J Exp Med (1997) 1.45

Mitogenic effect of a water-soluble extract of Nocardia opaca: a comparative study with some bacterial adjuvants on spleen and peripheral lymphocytes of four mammalian species. J Immunol (1974) 1.40

Myeloid dendritic cells. J Leukoc Biol (1999) 1.40

Stimulation of the primary mixed leukocyte reaction. Crit Rev Immunol (1985) 1.40

Self-inoculation with milk as a cause of recurrent cellulitis. Can Med Assoc J (1975) 1.38

Differentiation of an interleukin 3-dependent precursor B-cell clone into immunoglobulin-producing cells in vitro. Proc Natl Acad Sci U S A (1988) 1.36

Target cells for the activity of a synthetic adjuvant: muramyl dipeptide. Cell Immunol (1977) 1.36

Immune response to levan. III. The capacity to produce anti-inulin antibodies and cross-reactive idiotypes appears late in ontogeny. J Immunol (1979) 1.34

A human T-independent B lymphocyte mitogen extracted from Nocardia opaca. J Immunol (1976) 1.33

Evaluation of rotation thrombelastography for the diagnosis of hyperfibrinolysis in trauma patients. Br J Anaesth (2008) 1.31

Lymphokine production by murine T cells in the mixed leukocyte reaction. J Exp Med (1988) 1.31

Development and evaluation of immunoassay for detection of antibodies to the feline T-lymphotropic lentivirus (feline immunodeficiency virus). J Clin Microbiol (1989) 1.30

Macrophages, but not dendritic cells, accumulate colloidal carbon following administration in situ. J Cell Sci (1993) 1.27

A small number of anti-CD3 molecules on dendritic cells stimulate DNA synthesis in mouse T lymphocytes. J Exp Med (1989) 1.27

Stability over time of variables measuring heart rate variability in normal subjects. Am J Cardiol (1991) 1.27

Blast transformation of rabbit B-derived lymphocytes by a mitogen extracted from Nocardia. J Immunol (1975) 1.25

Characteristics of aneurysms arising from the horizontal portion of the anterior cerebral artery. Surg Neurol (2001) 1.24

Neonatal treatment with low doses of anti-idiotypic antibody leads to the expression of a silent clone. J Exp Med (1981) 1.24

[Serological evolution of infection by Plasmodium malariae: variations of fluorescent antibody titre after radical treatment]. Bull World Health Organ (1969) 1.22

Contrasting effects of TGF-beta 1 and TNF-alpha on the development of dendritic cells from progenitors in mouse bone marrow. Stem Cells (1997) 1.21

Immunogenicity: role of dendritic cells. Bioessays (1989) 1.20

Cloning and sequencing of the gene for Na+/H+ antiporter of Vibrio parahaemolyticus. Biochem Biophys Res Commun (1996) 1.20

Polyclonal activation of human B lymphocytes by Nocardia water soluble mitogen (NWSM). Immunol Rev (1979) 1.19

Murine V kappa gene expression does not follow the VH paradigm. J Exp Med (1989) 1.19

Cell suppression in PPD-induced blast specific response of human peripheral blood lymphocytes. Clin Exp Immunol (1976) 1.18

Presence and subcellular localization of two distinct mitogenic fractions in the cells of Nocardia rubra and Nocardia opaca: preparation of soluble mitogenic peptidoglycan fractions. Infect Immun (1976) 1.18

The effect of immunosuppressive agents on the induction of nuclear factors that bind to sites on the interleukin 2 promoter. J Exp Med (1990) 1.18

The fluorescent antibody technique in the estimation of immunity in patients infected with Plasmodium malariae. Trans R Soc Trop Med Hyg (1966) 1.17

[The value of the immunofluorescent reaction in the detection of asymptomatic parasitemia due to Plasmodium malariae]. Bull World Health Organ (1967) 1.17

Coexpression of NF-kappa B/Rel and Sp1 transcription factors in human immunodeficiency virus 1-induced, dendritic cell-T-cell syncytia. Proc Natl Acad Sci U S A (1995) 1.15

Cloning and sequencing of a novel Na+/H+ antiporter gene from Pseudomonas aeruginosa. Biochim Biophys Acta (1998) 1.15

Donor-derived chimerism in recipients of organ transplants. Hepatology (1993) 1.15

Regulation of the anti-inulin antibody response by a nonallotype-linked gene. J Exp Med (1980) 1.14

Mitogenic analysis of murine B-cell heterogeneity. J Exp Med (1978) 1.13

Lack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4R alpha and transforming growth factor-beta genes. J Invest Dermatol (2001) 1.13

Low responsiveness of hepatitis B virus-transgenic mice in antibody response to T-cell-dependent antigen: defect in antigen-presenting activity of dendritic cells. Immunology (1993) 1.13

Genetic and cellular regulation of the expression of specific antibody idiotypes in the anti-polyfructosan immune response. Ann Immunol (Paris) (1979) 1.10

The pharmacokinetics and serum and urine bactericidal activity of ciprofloxacin. J Clin Pharmacol (1985) 1.10

Dendritic cells: antigen presentation, accessory function and clinical relevance. Adv Exp Med Biol (1993) 1.09

Transfer of antigenic macromolecules from macrophages to lymphocytes. I. Autoradiographic and quantitative study of ( 14 C)endotoxin and ( 125 I)haemocyanin transfer. Immunology (1972) 1.09

Effect of L-arginine on the retention of macrophage tumoricidal activity. J Immunol (1991) 1.09