Expression of matrix metalloproteinases and their inhibitors in human brain tumors.

Magnetic nanoparticles in MR imaging and drug delivery. Adv Drug Deliv Rev (2008) 4.80

Specific targeting of brain tumors with an optical/magnetic resonance imaging nanoprobe across the blood-brain barrier. Cancer Res (2009) 2.28

In vivo MRI detection of gliomas by chlorotoxin-conjugated superparamagnetic nanoprobes. Small (2008) 2.09

PEG-mediated synthesis of highly dispersive multifunctional superparamagnetic nanoparticles: their physicochemical properties and function in vivo. ACS Nano (2010) 1.52

Metzincin proteases and their inhibitors: foes or friends in nervous system physiology? J Neurosci (2010) 1.41

Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9. Cancer Res (2009) 1.38

Tumor-targeted drug delivery and MRI contrast enhancement by chlorotoxin-conjugated iron oxide nanoparticles. Nanomedicine (Lond) (2008) 1.22

The expression of rho proteins decreases with human brain tumor progression: potential tumor markers. Clin Exp Metastasis (2002) 1.16

Differential expression and localization of TIMP-1 and TIMP-4 in human gliomas. Br J Cancer (2001) 1.03

TRAIL inhibits angiogenesis stimulated by VEGF expression in human glioblastoma cells. Br J Cancer (2006) 1.03

MMP-9, uPAR and cathepsin B silencing downregulate integrins in human glioma xenograft cells in vitro and in vivo in nude mice. PLoS One (2010) 0.93

Human macrophage metalloelastase worsens the prognosis of pancreatic cancer. Ann Surg (2002) 0.90

A complete compilation of matrix metalloproteinase expression in human malignant gliomas. World J Clin Oncol (2012) 0.89

Expression of integrin alpha6beta1 enhances tumorigenesis in glioma cells. Am J Pathol (2009) 0.89

Involvement of nitric oxide synthase in matrix metalloproteinase-9- and/or urokinase plasminogen activator receptor-mediated glioma cell migration. BMC Cancer (2013) 0.85

Expression of MMP-2 and MMP-9 in retinoblastoma and their significance. Int J Ophthalmol (2011) 0.84

Changes in laminin isoforms associated with brain tumor invasion and angiogenesis. Front Biosci (2006) 0.84

Possible role of matrix metalloproteinase in osteolytic intracranial meningiomas. J Korean Neurosurg Soc (2010) 0.83

MMP-9 and uPAR regulated glioma cell migration. Cell Adh Migr (2012) 0.83

Biomarkers of pediatric brain tumors. Front Pediatr (2013) 0.83

Molecular magnetic resonance imaging approaches used to aid in the understanding of the tissue regeneration marker Met in vivo: implications for tissue engineering. Tissue Eng Part A (2010) 0.80

Phase I and pharmacokinetic study of COL-3 in patients with recurrent high-grade gliomas. J Neurooncol (2011) 0.78

Antagonistic Effects of Endogenous Nitric Oxide in a Glioblastoma Photodynamic Therapy Model. Photochem Photobiol (2016) 0.78

Comparative Analysis of Matrix Metalloproteinase Family Members Reveals That MMP9 Predicts Survival and Response to Temozolomide in Patients with Primary Glioblastoma. PLoS One (2016) 0.75

Using Nanoparticles in Medicine for Liver Cancer Imaging. Oman Med J (2017) 0.75

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature (1994) 9.31

Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease. J Biol Chem (1995) 5.57

Quantitative zymography: detection of picogram quantities of gelatinases. Anal Biochem (1994) 3.37

The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study. J Biol Chem (1998) 2.71

Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation. Proc Natl Acad Sci U S A (1990) 2.68

Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms. J Clin Invest (1998) 2.43

Interaction of 92-kDa type IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase, and activation of the proenzyme with stromelysin. J Biol Chem (1992) 2.34

Extracellular matrix 6: role of matrix metalloproteinases in tumor invasion and metastasis. FASEB J (1993) 2.28

Molecular cloning and characterization of human tissue inhibitor of metalloproteinase 4. J Biol Chem (1996) 1.92

Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation. J Cell Physiol (1993) 1.88

Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP-2). J Cell Sci (1994) 1.86

Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas. Br J Cancer (1999) 1.71

The role of matrix metalloproteases and their inhibitors in tumour invasion, metastasis and angiogenesis. Eur Respir J (1994) 1.68

Activation of progelatinase B (MMP-9) by gelatinase A (MMP-2). Cancer Res (1995) 1.63

Angiogenesis in malignant gliomas. Glia (1995) 1.62

Molecular cloning and mRNA tissue distribution of a novel matrix metalloproteinase isolated from porcine enamel organ. Gene (1996) 1.56

Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis. Int J Cancer (1999) 1.52

Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP. J Biol Chem (1999) 1.52

Membrane-type matrix metalloproteinase 1 is a gelatinolytic enzyme and is secreted in a complex with tissue inhibitor of metalloproteinases 2. Cancer Res (1996) 1.45

Plasminogen activators and matrix metalloproteinases in angiogenesis. Enzyme Protein (1996) 1.42

Identification and structural and functional characterization of human enamelysin (MMP-20). Biochemistry (1997) 1.35

Correlation of the in situ detection of polymerase chain reaction-amplified metalloproteinase complementary DNAs and their inhibitors with prognosis in cervical carcinoma. Cancer Res (1995) 1.29

Expression and localization of matrix metalloproteinase-12 in the aorta of cholesterol-fed rabbits: relationship to lesion development. Am J Pathol (1998) 1.27

Overexpression of tissue inhibitor of metalloproteinases-2 retroviral-mediated gene transfer in vivo inhibits tumor growth and invasion. Cancer Res (1996) 1.22

Matrix metalloproteinases-2 and -9 are expressed in human neuroblastoma: contribution of stromal cells to their production and correlation with metastasis. Cancer Res (1998) 1.21

Inhibition of angiogenesis by tissue inhibitor of metalloproteinase. J Cell Physiol (1994) 1.21

MMP-2: expression, activation and inhibition. Enzyme Protein (1996) 1.19

Production of matrix metalloproteinases and tissue inhibitor of metalloproteinases-1 by human brain tumors. J Neurosurg (1994) 1.19

Identification and characterization of a novel human matrix metalloproteinase with unique structural characteristics, chromosomal location, and tissue distribution. J Biol Chem (1997) 1.17

Elevated levels of M(r) 92,000 type IV collagenase in human brain tumors. Cancer Res (1993) 1.16

Tissue inhibitor of metalloproteinase-2 stimulates fibroblast proliferation via a cAMP-dependent mechanism. J Biol Chem (1995) 1.16

Expression of matrix metalloproteinases and their tissue inhibitors in human brain tumors. Am J Pathol (1998) 1.15

Proteases and their inhibitors in human brain tumours: a review. Anticancer Res (1998) 1.13

Expression of tissue inhibitors of metalloproteinases: negative regulators of human glioblastoma invasion in vivo. Clin Exp Metastasis (1995) 1.05

Collagenases and tissue inhibitors of metalloproteinases: a functional balance in tissue degradation. Oral Dis (1996) 1.04

Complex roles of matrix metalloproteinases in tumor progression. Curr Top Microbiol Immunol (1996) 1.00

Identification and characterization of a novel collagenase in Xenopus laevis: possible roles during frog development. Mol Biol Cell (1996) 0.98

Identification of MMP-18, a putative novel human matrix metalloproteinase. Biochem Biophys Res Commun (1996) 0.97

Expression of a cleaved brain-specific extracellular matrix protein mediates glioma cell invasion In vivo. J Neurosci (1998) 0.96

Comparative analysis of matrix metalloproteinases by immunocytochemistry, immunohistochemistry and zymography in human primary brain tumours. Int J Oncol (1998) 0.96

Inhibition of metastasis in human gastric cancer cells transfected with tissue inhibitor of metalloproteinase 1 gene in nude mice. Cancer (1996) 0.92

Protease production by cultured microglia: substrate gel analysis and immobilized matrix degradation. J Neurosci Res (1993) 0.92

Up-regulation of TIMP-1 expression in B16-F10 melanoma cells suppresses their metastatic ability in chick embryo. Clin Exp Metastasis (1992) 0.86

A novel matrix metalloproteinase gene (XMMP) encoding vitronectin-like motifs is transiently expressed in Xenopus laevis early embryo development. J Biol Chem (1997) 0.85

Principles of the new World Health Organization (WHO) classification of brain tumors. Neuroradiology (1980) 0.84

Microvessel density in brain tumors. Anticancer Res (1998) 0.83

Expression of matrix metalloproteinases in human glioma cell lines in the presence of IL-10. J Neurooncol (1998) 0.80

Tumor angiogenesis: functional similarities with tumor invasion. EXS (1997) 0.79

Free radicals as mediators of tissue injury. Acta Physiol Scand Suppl (1980) 1.52

Matrix metalloproteinase inhibition by green tea catechins. Biochim Biophys Acta (2000) 1.48

The increase of cGMP by atrial natriuretic factor correlates with the distribution of particulate guanylate cyclase. FEBS Lett (1985) 1.36

Mucopolysaccharidoses and spinal cord compression: case report and review of the literature with implications of bone marrow transplantation. Neurosurgery (2000) 1.30

Gamma-interferon promotes proliferation of adult human astrocytes in vitro and reactive gliosis in the adult mouse brain in vivo. Proc Natl Acad Sci U S A (1991) 1.27

Endovascular treatment of acutely ruptured and unruptured aneurysms of the basilar bifurcation. J Neurosurg (1997) 1.23

DNA nicking favors PCR recombination. Nucleic Acids Res (1991) 1.21

Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep-2. Br J Pharmacol (2008) 1.20

Light-dependent phosphorylation of thylakoid membrane polypeptides. Biochem Biophys Res Commun (1979) 1.18

Endovascular treatment of ophthalmic segment aneurysms with Guglielmi detachable coils. AJNR Am J Neuroradiol (1997) 1.18

Localization of membrane-type 1 matrix metalloproteinase in caveolae membrane domains. Biochem J (2001) 1.17

Activation of the extracellular signal-regulated protein kinase (ERK) cascade by membrane-type-1 matrix metalloproteinase (MT1-MMP). FEBS Lett (2001) 1.11

Isolation of endothelial cells from brain, lung, and kidney: expression of the multidrug resistance P-glycoprotein isoforms. Biochem Biophys Res Commun (2001) 1.11

P-glycoprotein is localized in caveolae in resistant cells and in brain capillaries. FEBS Lett (2000) 1.11

Physiological roles of matrix metalloproteinases: implications for tumor growth and metastasis. Can J Physiol Pharmacol (1999) 1.10

P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain. Biochem J (1997) 1.10

Radioisotopic "subtraction" scanning for pancreatic lesions. Radiology (1967) 1.09

Localization of RhoA GTPase to endothelial caveolae-enriched membrane domains. Biochem Biophys Res Commun (1998) 1.08

Identification of an immunodominant ABC transporter in methicillin-resistant Staphylococcus aureus infections. Infect Immun (2000) 1.07

Canadian recommendations for the treatment of recurrent or progressive glioblastoma multiforme. Curr Oncol (2011) 1.06

A mouse embryo cell line carrying an inducible, temperature-sensitive, polyoma virus genome. Virology (1978) 1.03

Scalp nerve blocks decrease the severity of pain after craniotomy. Anesth Analg (2001) 1.00

Inducible permissive cells transformed by a temperature-sensitive polyoma virus: superinfection does not allow excision of the resident viral genome. J Virol (1981) 0.99

Regulation of cytoskeletal functions by Rho small GTP-binding proteins in normal and cancer cells. Can J Physiol Pharmacol (1996) 0.99

Aneurysm rupture after endovascular flow diversion: the possible role of persistent flows through the transition zone associated with device deformation. Interv Neuroradiol (2013) 0.99

Subcellular distribution and membrane association of Rho-related small GTP-binding proteins in kidney cortex. Am J Physiol (1995) 0.98

Immunodetection of a type III sodium-dependent phosphate cotransporter in tissues and OK cells. Biochim Biophys Acta (1998) 0.97

Dexamethasone modulation of multidrug transporters in normal tissues. FEBS Lett (1999) 0.97

Immunochemical characterization of L-isoaspartyl-protein carboxyl methyltransferase from mammalian tissues. Biochem J (1995) 0.96

Thrombosis heralding aneurysmal rupture: an exploration of potential mechanisms in a novel giant swine aneurysm model. AJNR Am J Neuroradiol (2012) 0.95

The in situ size of the dopamine transporter is a tetramer as estimated by radiation inactivation. Biochim Biophys Acta (1994) 0.94

Glycosphingolipids modulate renal phosphate transport in potassium deficiency. Kidney Int (2001) 0.93

Cellular localization of P-glycoprotein in brain versus gonadal capillaries. J Histochem Cytochem (1996) 0.93

Effect of stage of lactation and parity on mammary gland cell renewal. J Dairy Sci (2006) 0.93

The high molecular weight RNA of Visna virus. Biochimie (1973) 0.90

Expression of multidrug-resistance P-glycoprotein (MDR1) in human brain tumors. Int J Cancer (2001) 0.90

High levels of P-glycoprotein detected in isolated brain capillaries. Biochim Biophys Acta (1993) 0.90

Regulation of Rho protein binding to membranes by rhoGDI: inhibition of releasing activity by physiological ionic conditions. Biochem Cell Biol (1999) 0.89

Cisplatin induces renal expression of P-glycoprotein and canalicular multispecific organic anion transporter. Am J Physiol (1999) 0.89

Cyclosporin A treatment induces overexpression of P-glycoprotein in the kidney and other tissues. Am J Physiol (1996) 0.88

Multidrug resistance in brain tumors: roles of the blood-brain barrier. Cancer Metastasis Rev (2001) 0.87

Matrix proteinase inhibition by AE-941, a multifunctional antiangiogenic compound. Anticancer Res (2001) 0.87

Rapid activation of matrix metalloproteinase-2 by glioma cells occurs through a posttranslational MT1-MMP-dependent mechanism. Biochim Biophys Acta (2000) 0.87

The same mammalian replicon yields distinct recombination products in different cell lines. J Biol Chem (1991) 0.86

Involvement of disulphide bonds in the renal sodium/phosphate co-transporter NaPi-2. Biochem J (1997) 0.86

Demonstration of a novel type of ATP-diphosphohydrolase (EC 3.6.1.5) in the bovine lung. J Biol Chem (1993) 0.85

The renal brush border membrane in man. Protein pattern, inorganic phosphate binding and transport: comparison with other species. Ren Physiol (1984) 0.85

P-glycoprotein of blood brain barrier: cross-reactivity of Mab C219 with a 190 kDa protein in bovine and rat isolated brain capillaries. Biochim Biophys Acta (1995) 0.85

NaPO(4) cotransport type III (PiT1) expression in human embryonic kidney cells and regulation by PTH. Am J Physiol (1999) 0.84

Matrix metalloproteinases and their inhibitors in human pituitary tumors. Neurosurgery (1999) 0.84

Identification and localization of ATP-diphosphohydrolase (apyrase) in bovine aorta: relevance to vascular tone and platelet aggregation. Biochim Biophys Acta (1991) 0.84

Subcellular distribution and guanine nucleotide dependency of COOH-terminal methylation in kidney cortex. Am J Physiol (1993) 0.84

Bloodless open heart surgery with atraumatic extracorporeal circulation. Can Med Assoc J (1975) 0.84

Purification and characterization of metabolically active capillaries of the blood-brain barrier. Biochem J (1991) 0.83

Isoform I (mdr3) is the major form of P-glycoprotein expressed in mouse brain capillaries. Evidence for cross-reactivity of antibody C219 with an unrelated protein. Biochem J (1995) 0.83

Phosphate uptake by superficial and deep nephron brush border membranes. Effect of the dietary phosphate and parathyroid hormone. Pflugers Arch (1984) 0.83

Molecular size of a Na(+)-dependent amino acid transporter in Ehrlich ascites cell plasma membranes estimated by radiation inactivation. Biochemistry (1991) 0.83

Intracerebral gangliogliomas in patients with partial complex seizures: CT and MR imaging findings. AJNR Am J Neuroradiol (1991) 0.83

Phosphate deprivation induces overexpression of two proteins related to the rat renal phosphate cotransporter NaPi-2. Biochim Biophys Acta (1996) 0.82

Purification and characterization of a membrane-bound protein carboxyl methyltransferase from rat kidney cortex. J Biol Chem (1993) 0.82

pH gradient as an additional driving force in the renal re-absorption of phosphate. Biochem J (1990) 0.82

Immunodetection and characterization of proteins implicated in renal sodium/phosphate cotransport. Biochim Biophys Acta (1994) 0.82

Molecular study of P-glycoprotein in multidrug resistance using surface plasmon resonance. Anal Biochem (1995) 0.82

Radiation-inactivation analysis of the oligomeric structure of the renal sodium/D-glucose symporter. Biochim Biophys Acta (1997) 0.82

P-glycoprotein is strongly expressed in brain capillaries. Adv Exp Med Biol (1993) 0.82

Modulation of Rho and cytoskeletal protein attachment to membranes by a prenylcysteine analog. J Biol Chem (2000) 0.82

Further studies on the replication of adenovirus type 2 DNA. Can J Biochem (1978) 0.82

High-performance liquid chromatographic determination of diltiazem and four of its metabolites in plasma: evaluation of their stability. J Chromatogr (1988) 0.82

Fractionation of renal brush border membrane proteins with Triton X-114 phase partitioning. Biochem Cell Biol (1991) 0.81

Dopaminergic projection from nucleus raphe dorsalis to neostriatum in the rat. J Comp Neurol (1986) 0.81

Effect of arginine modification on kidney brush-border-membrane transport activity. Biochem J (1984) 0.81

Tyrosine phosphorylation of the vascular endothelial-growth-factor receptor-2 (VEGFR-2) is modulated by Rho proteins. Biochem J (2000) 0.81

Influence of glioma tumour microenvironment on the transport of ANG1005 via low-density lipoprotein receptor-related protein 1. Br J Cancer (2011) 0.81

Demonstration of an ectoATP-diphosphohydrolase (E.C.3.6.1.5.) in non-vascular smooth muscles of the bovine trachea. Biochim Biophys Acta (1994) 0.80

Intramolecular recombination in polyomavirus DNA is controlled by promoter elements. Nucleic Acids Res (1994) 0.80

The renal sodium/phosphate symporters: evidence for different functional oligomeric states. Biochemistry (1996) 0.80

Identification of the cyclosporin-binding site in P-glycoprotein. Biochemistry (1998) 0.80

Interaction of immunosuppressive agents rapamycin and its analogue SDZ-RAD with endothelial P-gp. Transplant Proc (2002) 0.80

Antioxidants to prevent bovine neutrophil-induced mammary epithelial cell damage. J Dairy Sci (2005) 0.80

Malignant rhabdoid tumor of brain: an aggressive clinical entity. Can J Neurol Sci (1996) 0.80

Molecular interactions of cyclosporin A with P-glycoprotein. Photolabeling with cyclosporin derivatives. J Biol Chem (1997) 0.80

Perioperative variability of binding of lidocaine, quinidine, and propranolol after cardiac operations. J Thorac Cardiovasc Surg (1988) 0.79

RhoB expression is induced after the transient upregulation of RhoA and Cdc42 during neuronal differentiation and influenced by culture substratum and microtubule integrity. Brain Res Dev Brain Res (2001) 0.79

Human cerebral endothelium: isolation and characterization of cells derived from microvessels of non-neoplastic and malignant glial tissue. J Neurooncol (1990) 0.79

Phosphate transport by capillaries of the blood-brain barrier. J Biol Chem (1992) 0.79

Palmitoylation of the glucose transporter in blood-brain barrier capillaries. Biochim Biophys Acta (1995) 0.79

Use of capillary electrophoresis for the characterization of human serum albumin heterogeneity. Biomed Chromatogr (1998) 0.79