Published in J Clin Invest on October 01, 1976
Experimental Haemophilus influenzae type b meningitis: immunological investigation of the infant rat model. Infect Immun (1978) 2.46
Phenotypic and genetic variation in the susceptibility of Haemophilus influenzae type b to antibodies to somatic antigens. J Clin Invest (1980) 2.42
Characterization of Haemophilus influenzae type b fimbriae. Infect Immun (1984) 2.00
Haemophilus influenzae bacteremia and meningitis resulting from survival of a single organism. Proc Natl Acad Sci U S A (1978) 1.88
Antigenic diversity of lipooligosaccharides of nontypable Haemophilus influenzae. Infect Immun (1987) 1.87
Further studies of the role of noncapsular antibody in protection against experimental Haemophilus influenzae type b bacteremia. Infect Immun (1983) 1.78
Comparative virulence of Haemophilus influenzae with a type b or type d capsule. Infect Immun (1981) 1.66
Opsonizing and bactericidal effects of normal human serum on nontypable Haemophilus influenzae. Infect Immun (1983) 1.62
K-1 antigen of Escherichia coli: epidemiology and serum sensitivity of pathogenic strains. Infect Immun (1978) 1.23
Outer membrane protein D15 is conserved among Haemophilus influenzae species and may represent a universal protective antigen against invasive disease. Infect Immun (1997) 1.17
Serum opsonic activity after immunization of adults with Haemophilus influenzae type b-diphtheria toxoid conjugate vaccine. Infect Immun (1985) 1.09
Comparison of cefamandole, cephalothin, ampicillin, and chloramphenicol in experimental Escherichia coli meningitis. Antimicrob Agents Chemother (1980) 1.04
Lactate stimulation of gonococcal metabolism in media containing glucose: mechanism, impact on pathogenicity, and wider implications for other pathogens. Infect Immun (2001) 1.01
Effects of human serum on the growth and metabolism of Neisseria gonorrhoeae: an alternative view of serum. Infect Immun (1985) 0.94
A 20-kilodalton N-terminal fragment of the D15 protein contains a protective epitope(s) against Haemophilus influenzae type a and type b. Infect Immun (1998) 0.89
Participation of complement in host defense against capsule-deficient Haemophilus influenzae. Infect Immun (1983) 0.88
Paradoxical effect of pilus expression on binding of antibodies by Haemophilus influenzae. Infect Immun (1993) 0.86
Challenge of investigating biologically relevant functions of virulence factors in bacterial pathogens. Philos Trans R Soc Lond B Biol Sci (2000) 0.85
Antibody to the outer membrane proteins is the dominant opsonic antibody in normal human serum against H. influenzae type b. Immunology (1989) 0.82
Complement component 3 binding to Haemophilus influenzae type b in the presence of anticapsular and anti-outer membrane antibodies. Infect Immun (1992) 0.82
Multiple mechanisms in serum factor-induced resistance of Haemophilus influenzae type b to antibody. Infect Immun (1990) 0.81
Experimental meningitis in the rat: Haemophilus influenzae. Infection (1984) 0.80
Characterization of lactate utilization and its implication on the physiology of Haemophilus influenzae. Int J Med Microbiol (2014) 0.79
Outer membrane protein binding sites of complement component 3 during opsonization of Haemophilus influenzae. Infect Immun (1993) 0.79
Comparison of in vivo and in vitro multiplication rates of Haemophilus influenzae type b. Infect Immun (1986) 0.78
Rapid differentiation of bacterial meningitides by direct gas-liquid chromatography. J Clin Invest (1982) 0.75
Pericarditis caused by beta-lactamase-producing Haemophilus influenzae: report of two cases in adults and review of the literature. Tex Heart Inst J (1986) 0.75
Human immunity to the meningococcus. I. The role of humoral antibodies. J Exp Med (1969) 13.87
Human serum activities against Hemophilus influenzae, type b. J Clin Invest (1972) 7.85
Production of Haemophilus influenzae b meningitis in infant rats by intraperitoneal inoculation. Infect Immun (1973) 4.80
The complement-dependent bacteriolytic activity of normal human serum. I. The effect of pH and ionic strength and the role of lysozyme. J Exp Med (1962) 3.81
The sensitivity to complement of strains of Escherichia coli related to their K antigens. Immunology (1970) 3.53
Cell wall composition and virulence in Escherichia coli. J Exp Med (1968) 3.36
Responses of children immunized with the capsular polysaccharide of Hemophilus influenzae, type b. Pediatrics (1973) 3.33
Gonococci in urethral exudates possess a virulence factor lost on subculture. Nature (1970) 3.19
KINETICS OF THE BACTERICIDAL ACTION OF NORMAL SERUM ON GRAM-NEGATIVE BACTERIA. J Immunol (1965) 2.80
Sensitivity of rough gram-negative bacteria to the bactericidal action of serum. J Bacteriol (1968) 2.68
A proposed mechanism for natural immunity to enterobacterial pathogens. J Immunol (1968) 2.66
Circulating polyribophosphate in Hemophilus influenzae, type b meningitis. Correlation with clinical course and antibody response. J Clin Invest (1975) 2.48
Induction of serum Haemophilus influenzae type B capsular antibodies in adult volunteers fed cross-reacting Escherichia coli 075:K100:H5. N Engl J Med (1975) 2.16
The serum bactericidal reaction. IV. Phenotypic conversion of Escherichia coli from serum-resistance to serum-sensitivity by diphenylamine. J Infect Dis (1969) 2.02
THE CHEMICAL BASIS OF THE VIRULENCE OF BRUCELLA ABORTUS. V. THE BASIS OF INTRACELLULAR SURVIVAL AND GROWTH IN BOVINE PHAGOCYTES. Br J Exp Pathol (1964) 1.99
Immunologic responses to Hemophilus influenzae meningitis. J Pediatr (1972) 1.53
Sensitization of complement resistant bacterial strains. Nature (1969) 1.40
Effects of serum components on gram-negative bacteria during bactericidal reactions. Infect Immun (1971) 1.39
Phagocytosis, with particular reference to encapsulated bacteria. Bacteriol Rev (1960) 1.37
The survival of strains of enteric bacilli in the blood stream as related to their sensitivity to the bactericidal effect of serum. J Clin Invest (1960) 1.30
Passive sensitization of Salmonella adelaide to the bactericidal action of antibody and complement. Nature (1968) 1.29
Blocking serum lysis of Brucella abortus by hyperimmune rabbit immunoglubulin A. J Immunol (1971) 1.29
A factor in the serum of patients with persisting infection that inhibits the bactericidal activity of normal serum against the organism that is causing the infection. J Immunol (1966) 1.28
Separation of serum bactericidal and opsonizing activities for Haemophilus influenzae type b. Infect Immun (1973) 1.27
Immunologic response in patients with epiglottitis caused by Haemophilus influenzae type b. J Infect Dis (1973) 1.21
Reassessment of the role of bactericidal antibody in Hemophilus influenzae infection. Am J Med Sci (1971) 1.19
Prevalence of bactericidal antibodies to Haemophilus influenzae, type b. J Infect Dis (1974) 1.10
Bactericidal antibodies to Hemophilus influenzae. Proc Soc Exp Biol Med (1971) 0.88
The effects of serum components on the agglutination of Gram-negative bacteria. Can J Microbiol (1970) 0.88
Mechanism of immunity in haemorrhagic septicaemia. Nature (1960) 0.81
In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity. J Virol (1988) 12.52
Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus. Nature (1985) 12.08
Evaluation of protein A gene polymorphic region DNA sequencing for typing of Staphylococcus aureus strains. J Clin Microbiol (1999) 11.77
Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor. Cell (1987) 11.56
Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein. Cell (1987) 11.15
RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules. J Cell Biol (1999) 8.07
Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. The Pulmozyme Study Group. N Engl J Med (1994) 7.98
Human serum activities against Hemophilus influenzae, type b. J Clin Invest (1972) 7.85
Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis. J Pathol (1984) 6.67
A rapid chemical assay for gentamicin. N Engl J Med (1972) 6.36
Intermittent administration of inhaled tobramycin in patients with cystic fibrosis. Cystic Fibrosis Inhaled Tobramycin Study Group. N Engl J Med (1999) 6.23
Stress granules: sites of mRNA triage that regulate mRNA stability and translatability. Biochem Soc Trans (2002) 6.08
Dynamic shuttling of TIA-1 accompanies the recruitment of mRNA to mammalian stress granules. J Cell Biol (2000) 5.99
mRNA surveillance by the Caenorhabditis elegans smg genes. Genes Dev (1993) 5.94
Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene. Nature (1983) 5.90
Human naive and memory T cells: reinterpretation of helper-inducer and suppressor-inducer subsets. Immunol Today (1989) 5.86
Outer membrane protein composition in disease isolates of Haemophilus influenzae: pathogenic and epidemiological implications. Infect Immun (1980) 5.68
A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells. Cell (1991) 5.65
Comparison of phenotypic and genotypic techniques for identification of unusual aerobic pathogenic gram-negative bacilli. J Clin Microbiol (1998) 5.27
Transferable R factors in enteric bacteria causing infection of the genitourinary tract. Lancet (1966) 5.01
Haemophilus influenzae meningitis in infant rats after intranasal inoculation. J Infect Dis (1974) 4.94
Longitudinal assessment of Pseudomonas aeruginosa in young children with cystic fibrosis. J Infect Dis (2000) 4.93
Spontaneous tandem genetic duplications in Salmonella typhimurium arise by unequal recombination between rRNA (rrn) cistrons. Proc Natl Acad Sci U S A (1981) 4.85
Production of Haemophilus influenzae b meningitis in infant rats by intraperitoneal inoculation. Infect Immun (1973) 4.80
Regulated expression and binding of three VLA (beta 1) integrin receptors on T cells. Nature (1990) 4.66
Effect of systemic glucocorticoids on exacerbations of chronic obstructive pulmonary disease. Department of Veterans Affairs Cooperative Study Group. N Engl J Med (1999) 4.66
R factors mediate resistance to mercury, nickel, and cobalt. Science (1967) 4.57
T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-1 beta. Nature (1993) 4.57
TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha. EMBO J (2000) 4.41
Expression of active human factor VIII from recombinant DNA clones. Nature (1984) 4.36
Standardization of an opsonophagocytic assay for the measurement of functional antibody activity against Streptococcus pneumoniae using differentiated HL-60 cells. Clin Diagn Lab Immunol (1997) 4.28
Characterization of non-beta-lactamase-mediated ampicillin resistance in Haemophilus influenzae. Antimicrob Agents Chemother (1984) 4.25
Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1. Nature (2000) 4.12
Identification and nucleotide sequence of a human locus homologous to the v-myc oncogene of avian myelocytomatosis virus MC29. Nature (1983) 4.06
Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis. Gut (2009) 4.06
The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells. J Immunol (1990) 4.03
2-Aryl tryptamines: selective high-affinity antagonists for the h5-HT2A receptor. Bioorg Med Chem Lett (2000) 4.03
Cloning, nucleotide sequence, and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (1984) 3.98
Smoking cessation in patients with chronic obstructive pulmonary disease: a double-blind, placebo-controlled, randomised trial. Lancet (2001) 3.96
Human cytotoxic response in vitro to trinitrophenyl-modified autologous cells. I. T cell recognition of TNP in association with widely shared antigens. J Immunol (1978) 3.90
Chronic Lyme borreliosis in the laboratory mouse. Am J Pathol (1993) 3.82
Marburg-virus disease in Kenya. Lancet (1982) 3.79
A discrete element 3' of human immunodeficiency virus 1 (HIV-1) and HIV-2 mRNA initiation sites mediates transcriptional activation by an HIV trans activator. Mol Cell Biol (1988) 3.74
Defining substance use disorders: do we really need more than heavy use? Alcohol Alcohol (2013) 3.72
A new kind of informational suppression in the nematode Caenorhabditis elegans. Genetics (1989) 3.69
Activation-independent binding of human memory T cells to adhesion molecule ELAM-1. Nature (1991) 3.45
Responses of children immunized with the capsular polysaccharide of Hemophilus influenzae, type b. Pediatrics (1973) 3.33
Lymphocyte interactions with endothelial cells. Immunol Today (1992) 3.31
Improved enzymatic assay of chloramphenicol. Clin Chem (1978) 3.31
Two antigen-independent adhesion pathways used by human cytotoxic T-cell clones. Nature (1986) 3.24
SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast. Mol Cell Biol (1999) 3.18
Primary structure and biochemical properties of an M2 muscarinic receptor. Science (1987) 3.16
The T lymphocyte glycoprotein CD2 binds the cell surface ligand LFA-3. Nature (1987) 3.13
ICAM-1 a ligand for LFA-1-dependent adhesion of B, T and myeloid cells. Nature (1988) 3.12
General practitioners and alternative medicine. J R Coll Gen Pract (1987) 3.10
Mode of action of novobiocin in Escherichia coli. J Bacteriol (1967) 3.09
Rapid diagnosis of Hemophilus influenzae type b infections by latex particle agglutination and counterimmunoelectrophoresis. J Pediatr (1978) 3.05
Life and death in the cytoplasm: messages from the 3' end. Curr Opin Genet Dev (1997) 3.01
Activation of a transposable element in the germ line but not the soma of Caenorhabditis elegans. Nature (1987) 3.00
The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicing. Mol Cell (2000) 2.97
Leucocyte-endothelial interactions and regulation of leucocyte migration. Lancet (1994) 2.96
The toxicologic and pharmacologic properties of amantadine hydrochloride. Toxicol Appl Pharmacol (1969) 2.95
Cords, channels, corridors and conduits: critical architectural elements facilitating cell interactions in the lymph node cortex. Immunol Rev (1997) 2.89
Individual RNA recognition motifs of TIA-1 and TIAR have different RNA binding specificities. J Biol Chem (1996) 2.89
Electron microscope observations on compounds 48-80-induced degranulation in rat mast cells. Evidence for sequential exocytosis of storage granules. J Cell Biol (1971) 2.88
Identification of coryneform bacterial isolates by ribosomal DNA sequence analysis. J Clin Microbiol (2000) 2.87
Molecular basis of sequestration in severe and uncomplicated Plasmodium falciparum malaria: differential adhesion of infected erythrocytes to CD36 and ICAM-1. J Infect Dis (1991) 2.87
Do pili play a role in pathogenicity of Haemophilus influenzae type B? Lancet (1982) 2.84
Immunization of humans with polyribophosphate, the capsular antigen of Hemophilus influenzae, type b. J Clin Invest (1972) 2.81
Possible involvement of the OKT4 molecule in T cell recognition of class II HLA antigens. Evidence from studies of cytotoxic T lymphocytes specific for SB antigens. J Exp Med (1982) 2.81
Hemophilus influenzae type B susceptibility to 17 antibiotics. J Pediatr (1975) 2.74
Evidence for alteration of the vitamin D-endocrine system in blacks. J Clin Invest (1985) 2.72
Lyme borreliosis in genetically resistant and susceptible mice with severe combined immunodeficiency. Am J Trop Med Hyg (1992) 2.71
Roles of adhesion molecules in T-cell recognition: fundamental similarities between four integrins on resting human T cells (LFA-1, VLA-4, VLA-5, VLA-6) in expression, binding, and costimulation. Immunol Rev (1990) 2.68
Nucleotide sequence to the v-myc oncogene of avian retrovirus MC29. Proc Natl Acad Sci U S A (1983) 2.66
Role of interleukin-15 in the development of human CD56+ natural killer cells from CD34+ hematopoietic progenitor cells. Blood (1996) 2.62
Screening for alcohol abuse using the CAGE questionnaire. Am J Med (1987) 2.61
Evidence for alteration of the vitamin D-endocrine system in obese subjects. J Clin Invest (1985) 2.61
Increased rate of tuberculin skin test conversion among workers at a university hospital. Infect Control Hosp Epidemiol (1992) 2.60
Inhibition of protein synthesis by spectinomycin. Science (1965) 2.54
What are safe levels of alcohol consumption? Br Med J (Clin Res Ed) (1984) 2.54
Dual role of the CD44 molecule in T cell adhesion and activation. J Immunol (1989) 2.53
Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C. elegans. Genes Dev (2000) 2.52
Circulating polyribophosphate in Hemophilus influenzae, type b meningitis. Correlation with clinical course and antibody response. J Clin Invest (1975) 2.48
Gentamicin:adenine mononucleotide transferase: partial purification, characterization, and use in the clinical quantitation of gentamicin. J Infect Dis (1974) 2.45
The costs of treating COPD in the United States. Chest (2001) 2.43
Phenotypic and genetic variation in the susceptibility of Haemophilus influenzae type b to antibodies to somatic antigens. J Clin Invest (1980) 2.42