Immunity and the prospects for vaccination against filariasis.

PubWeight™: 0.84‹?›

🔗 View Article (PMID 1587547)

Published in Immunobiology on February 01, 1992

Authors

M E Selkirk1, R M Maizels, M Yazdanbakhsh

Author Affiliations

1: Wellcome Research Centre for Parasitic Infections, Department of Biochemistry, Imperial College of Science, Technology and Medicine, London, U.K.

Articles by these authors

Decreased atopy in children infected with Schistosoma haematobium: a role for parasite-induced interleukin-10. Lancet (2000) 4.32

Th2 responses without atopy: immunoregulation in chronic helminth infections and reduced allergic disease. Trends Immunol (2001) 2.94

Th1-Th2: reliable paradigm or dangerous dogma? Immunol Today (1997) 2.83

Severe reactions to filarial chemotherapy and release of Wolbachia endosymbionts into blood. Lancet (2001) 2.03

Co-infection of helminths and malaria: modulation of the immune responses to malaria. Parasite Immunol (2006) 1.89

Antischistosome IgG4 and IgE responses are affected differentially by chemotherapy in children versus adults. J Infect Dis (1996) 1.87

Application of a circulating-cathodic-antigen (CCA) strip test and real-time PCR, in comparison with microscopy, for the detection of Schistosoma haematobium in urine samples from Ghana. Ann Trop Med Parasitol (2008) 1.78

Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell-to-cell contact. Eur J Immunol (2000) 1.78

Elevated cellular immune responses and interferon-gamma release after long-term diethylcarbamazine treatment of patients with human lymphatic filariasis. J Infect Dis (1995) 1.74

Epitope specificity of the T cell proliferative response to lysozyme: proliferative T cells react predominantly to different determinants from those recognized by B cells. Eur J Immunol (1980) 1.62

A Brugia malayi homolog of macrophage migration inhibitory factor reveals an important link between macrophages and eosinophil recruitment during nematode infection. J Immunol (2001) 1.60

CD24(hi)CD27(+) B cells from patients with allergic asthma have impaired regulatory activity in response to lipopolysaccharide. Clin Exp Allergy (2014) 1.56

Differential expression of IgE and IgG4 specific antibody responses in asymptomatic and chronic human filariasis. J Immunol (1993) 1.51

The abundant larval transcript-1 and -2 genes of Brugia malayi encode stage-specific candidate vaccine antigens for filariasis. Infect Immun (2000) 1.50

Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses. Eur J Immunol (2000) 1.49

Atopy and malaria. Wien Klin Wochenschr (2001) 1.48

The prevalence of parasite infestation and house dust mite sensitization in Gabonese schoolchildren. Int Arch Allergy Immunol (2001) 1.47

Identification of tgh-2, a filarial nematode homolog of Caenorhabditis elegans daf-7 and human transforming growth factor beta, expressed in microfilarial and adult stages of Brugia malayi. Infect Immun (2000) 1.46

T-cell activation and the balance of antibody isotypes in human lymphatic filariasis. Parasitol Today (1995) 1.45

Bm-CPI-2, a cystatin homolog secreted by the filarial parasite Brugia malayi, inhibits class II MHC-restricted antigen processing. Curr Biol (2001) 1.43

Infection of IL-4-deficient mice with the parasitic nematode Brugia malayi demonstrates that host resistance is not dependent on a T helper 2-dominated immune response. J Immunol (1995) 1.40

Doxycycline treatment of Brugia malayi-infected persons reduces microfilaremia and adverse reactions after diethylcarbamazine and albendazole treatment. Clin Infect Dis (2008) 1.38

Chitinases and chitinase-like proteins: potential therapeutic targets for the treatment of T-helper type 2 allergies. Clin Exp Allergy (2009) 1.33

Immunological focusing by th mouse major histocompatibility complex: mouse strains confronted with distantly related lysozymes confine their attention to very few epitopes. Eur J Immunol (1982) 1.29

Cellular and humoral responses to influenza in gabonese children living in rural and semi-urban areas. J Infect Dis (2007) 1.29

APC from mice harbouring the filarial nematode, Brugia malayi, prevent cellular proliferation but not cytokine production. Int Immunol (1996) 1.28

Expression and immune recognition of Brugia malayi VAL-1, a homologue of vespid venom allergens and Ancylostoma secreted proteins. Mol Biochem Parasitol (2001) 1.26

Filarial-specific IgG4 response correlates with active Wuchereria bancrofti infection. J Immunol (1990) 1.26

Shared carbohydrate epitopes on distinct surface and secreted antigens of the parasitic nematode Toxocara canis. J Immunol (1987) 1.25

Antigen-specific proliferation and interferon-gamma and interleukin-5 production are down-regulated during Schistosoma haematobium infection. J Infect Dis (1998) 1.21

Adult and microfilarial stages of the filarial parasite Brugia malayi stimulate contrasting cytokine and Ig isotype responses in BALB/c mice. J Immunol (1994) 1.20

Nippostrongylus brasiliensis: cytokine responses and nematode expulsion in normal and IL-4-deficient mice. Exp Parasitol (1996) 1.20

Serine proteinase inhibitors from nematodes and the arms race between host and pathogen. Trends Biochem Sci (2001) 1.19

Multicentre laboratory evaluation of Brugia Rapid dipstick test for detection of brugian filariasis. Trop Med Int Health (2003) 1.18

Characterization of surface and excretory-secretory antigens of Toxocara canis infective larvae. Parasite Immunol (1984) 1.17

T1/ST2 expression is enhanced on CD4+ T cells from schistosome egg-induced granulomas: analysis of Th cell cytokine coexpression ex vivo. J Immunol (1999) 1.16

A novel member of the transforming growth factor-beta (TGF-beta) superfamily from the filarial nematodes Brugia malayi and B. pahangi. Exp Parasitol (1998) 1.16

Identification of abundantly expressed novel and conserved genes from the infective larval stage of Toxocara canis by an expressed sequence tag strategy. Infect Immun (1999) 1.15

T cell responsiveness correlates differentially with antibody isotype levels in clinical and asymptomatic filariasis. J Infect Dis (1993) 1.14

The multinational birth cohort of EuroPrevall: background, aims and methods. Allergy (2009) 1.14

Elevated proliferation and interleukin-4 release from CD4+ cells after chemotherapy in human Schistosoma haematobium infection. Eur J Immunol (1996) 1.12

Immunology of human helminth infection. Int Arch Allergy Immunol (1996) 1.12

Depression of antigen-specific interleukin-5 and interferon-gamma responses in human lymphatic filariasis as a function of clinical status and age. J Infect Dis (1997) 1.11

CD30 expression does not discriminate between human Th1- and Th2-type T cells. J Immunol (1996) 1.10

An abundant, trans-spliced mRNA from Toxocara canis infective larvae encodes a 26-kDa protein with homology to phosphatidylethanolamine-binding proteins. J Biol Chem (1995) 1.10

Helminth C-type lectins and host-parasite interactions. Parasitol Today (2000) 1.09

Toxocara canis: a labile antigenic surface coat overlying the epicuticle of infective larvae. Exp Parasitol (1992) 1.09

Nematode surface coats: actively evading immunity. Parasitol Today (1992) 1.08

A novel serpin expressed by blood-borne microfilariae of the parasitic nematode Brugia malayi inhibits human neutrophil serine proteinases. Blood (1999) 1.08

Schistosome glycans and innate immunity. Parasite Immunol (2005) 1.06

Age-specific acquisition of immunity to infective larvae in a bancroftian filariasis endemic area of Papua New Guinea. Parasite Immunol (1991) 1.06

An abundantly expressed mucin-like protein from Toxocara canis infective larvae: the precursor of the larval surface coat glycoproteins. Proc Natl Acad Sci U S A (1996) 1.05

A novel C-type lectin secreted by a tissue-dwelling parasitic nematode. Curr Biol (1999) 1.04

Differentially expressed, abundant trans-spliced cDNAs from larval Brugia malayi. Mol Biochem Parasitol (1997) 1.04

Specificity of surface molecules of adult Brugia parasites: cross-reactivity with antibody from Wuchereria, Onchocerca and other human filarial infections. Trop Med Parasitol (1985) 1.04

Biochemical properties of larval excretory-secretory glycoproteins of the parasitic nematode Toxocara canis. Mol Biochem Parasitol (1986) 1.04

Differential decline in filaria-specific IgG1, IgG4, and IgE antibodies in Brugia malayi-infected patients after diethylcarbamazine chemotherapy. J Infect Dis (1995) 1.03

Acquired immune heterogeneity and its sources in human helminth infection. Parasitology (2010) 1.03

Restricted sets of parasite antigens from the surface of different stages and sexes of the nematode parasite Nippostrongylus brasiliensis. Immunology (1983) 1.03

Purification of eosinophils from normal human blood, preparation of eosinoplasts and characterization of their functional response to various stimuli. Immunology (1987) 1.03

A family of secreted mucins from the parasitic nematode Toxocara canis bears diverse mucin domains but shares similar flanking six-cysteine repeat motifs. J Biol Chem (2000) 1.03

A filter paper technique for the detection of anti-filarial IgG4 in lymphatic filariasis. Trans R Soc Trop Med Hyg (1996) 1.02

A comparison of ex vivo cytokine production in venous and capillary blood. Clin Exp Immunol (2007) 1.01

Eosinophils do respond to fMLP. Blood (1987) 1.01

Characterization of nematode glycoproteins: the major O-glycans of Toxocara excretory-secretory antigens are O-methylated trisaccharides. Glycobiology (1991) 1.00

Requirement for in vivo production of IL-4, but not IL-10, in the induction of proliferative suppression by filarial parasites. J Immunol (1998) 0.99

Vaccination against helminth parasites--the ultimate challenge for vaccinologists? Immunol Rev (1999) 0.98

Diagnosis of human toxocariasis by antigen capture enzyme linked immunosorbent assay. J Clin Pathol (1993) 0.98

Molecules on the surface of parasitic nematodes as probes of the immune response in infection. Immunol Rev (1982) 0.97

The serpin secreted by Brugia malayi microfilariae, Bm-SPN-2, elicits strong, but short-lived, immune responses in mice and humans. J Immunol (2000) 0.97

Repeated patent infection of adult dogs with Toxocara canis. J Helminthol (1984) 0.96

Phosphorylcholine-bearing antigens in filarial nematode parasites: analysis of somatic extracts, in-vitro secretions and infection sera from Brugia malayi and B. pahangi. Parasite Immunol (1987) 0.96

Conditions for the development of IgM- and IgG-antibody-secreting cells from primed mouse splenocytes in vitro. Immunology (1977) 0.96

Characterization of the interaction of human eosinophils and neutrophils with opsonized particles. J Immunol (1985) 0.95

Antibody responses to filarial infective larvae are not dominated by the IgG4 isotype. Parasite Immunol (1998) 0.95

Cellular and humoral responses to tetanus vaccination in Gabonese children. Vaccine (2008) 0.95

Interleukin-12 suppresses immunoglobulin E production but enhances immunoglobulin G4 production by human peripheral blood mononuclear cells. Infect Immun (1997) 0.94

Identification, synthesis and immunogenicity of cuticular collagens from the filarial nematodes Brugia malayi and Brugia pahangi. Mol Biochem Parasitol (1989) 0.94

Identification of a new C-type lectin, TES-70, secreted by infective larvae of Toxocara canis, which binds to host ligands. Parasitology (2000) 0.94

Species-specific and common epitopes on the secreted and surface antigens of Toxocara cati and Toxocara canis infective larvae. Parasite Immunol (1987) 0.94

Heat shock cognate 70 is a prominent immunogen in Brugian filariasis. J Immunol (1989) 0.94

Requirement for in vivo production of IL-4, but not IL-10, in the induction of proliferative suppression by filarial parasites. J Immunol (1998) 0.93

daf-7-related TGF-beta homologues from Trichostrongyloid nematodes show contrasting life-cycle expression patterns. Parasitology (2009) 0.93

Cuticular localisation and turnover of the major surface glycoprotein (gp29) of adult Brugia malayi. Mol Biochem Parasitol (1990) 0.92

Killing of schistosomula by taurine chloramine and taurine bromamine. Am J Trop Med Hyg (1987) 0.92

Recognition of schistosome glycolipids by immunoglobulin E: possible role in immunity. Infect Immun (1999) 0.91

Adults acquire filarial infection more rapidly than children: a study in Indonesian transmigrants. Parasitology (2001) 0.91

Anti-schistosome IgG4 and IgE at 2 years after chemotherapy: infected versus uninfected individuals. J Infect Dis (1997) 0.91

Ascaris suum-derived products induce human neutrophil activation via a G protein-coupled receptor that interacts with the interleukin-8 receptor pathway. Infect Immun (2001) 0.90

Brugia pahangi and Brugia malayi: a surface-associated glycoprotein (gp15/400) is composed of multiple tandemly repeated units and processed from a 400-kDa precursor. Exp Parasitol (1993) 0.90