Published in J Biol Chem on June 23, 2000
High density lipoprotein structure-function and role in reverse cholesterol transport. Subcell Biochem (2010) 1.69
Class B scavenger receptor types I and II and CD36 targeting improves sepsis survival and acute outcomes in mice. J Immunol (2012) 1.61
Molecular mechanisms of cellular cholesterol efflux. J Biol Chem (2014) 1.44
CLA-1 and its splicing variant CLA-2 mediate bacterial adhesion and cytosolic bacterial invasion in mammalian cells. Proc Natl Acad Sci U S A (2006) 1.10
Glycine dimerization motif in the N-terminal transmembrane domain of the high density lipoprotein receptor SR-BI required for normal receptor oligomerization and lipid transport. J Biol Chem (2011) 1.02
Exoplasmic cysteine Cys384 of the HDL receptor SR-BI is critical for its sensitivity to a small-molecule inhibitor and normal lipid transport activity. Proc Natl Acad Sci U S A (2011) 1.01
Molecules that mimic apolipoprotein A-I: potential agents for treating atherosclerosis. J Med Chem (2013) 0.98
Class B scavenger receptor types I and II and CD36 mediate bacterial recognition and proinflammatory signaling induced by Escherichia coli, lipopolysaccharide, and cytosolic chaperonin 60. J Immunol (2011) 0.92
Extracellular disulfide bonds support scavenger receptor class B type I-mediated cholesterol transport. Biochemistry (2011) 0.91
Extracellular hydrophobic regions in scavenger receptor BI play a key role in mediating HDL-cholesterol transport. Arch Biochem Biophys (2010) 0.90
Negatively cooperative binding of high-density lipoprotein to the HDL receptor SR-BI. Biochemistry (2011) 0.89
SR-BI selective lipid uptake: subsequent metabolism of acute phase HDL. Arterioscler Thromb Vasc Biol (2009) 0.83
Several Human Liver Cell Expressed Apolipoproteins Complement HCV Virus Production with Varying Efficacy Conferring Differential Specific Infectivity to Released Viruses. PLoS One (2015) 0.83
Lipid-free Apolipoprotein A-I Structure: Insights into HDL Formation and Atherosclerosis Development. Arch Med Res (2015) 0.83
Lipoprotein receptors and lipid enzymes in hepatitis C virus entry and early steps of infection. Scientifica (Cairo) (2012) 0.77
Protein mediators of sterol transport across intestinal brush border membrane. Subcell Biochem (2010) 0.76
Human SR-BII mediates SAA uptake and contributes to SAA pro-inflammatory signaling in vitro and in vivo. PLoS One (2017) 0.75
Interferon alpha bioactivity critically depends on Scavenger receptor class B type I function. Oncoimmunology (2016) 0.75
Micellar lipid composition affects micelle interaction with class B scavenger receptor extracellular loops. J Lipid Res (2015) 0.75
Antiinflammatory properties of HDL. Circ Res (2004) 5.41
Cellular cholesterol efflux mediated by cyclodextrins. J Biol Chem (1995) 4.86
DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell (1995) 4.64
Use of cyclodextrins for manipulating cellular cholesterol content. J Lipid Res (1997) 4.44
Nucleotide sequence of the gene for a fibronectin-binding protein from Staphylococcus aureus: use of this peptide sequence in the synthesis of biologically active peptides. Proc Natl Acad Sci U S A (1989) 3.94
The amphipathic helix in the exchangeable apolipoproteins: a review of secondary structure and function. J Lipid Res (1992) 3.74
Amphipathic helix motif: classes and properties. Proteins (1990) 3.52
Monolayer characteristics of saturated 1,2,-diacyl phosphatidylcholines (lecithins) and phosphatidylethanolamines at the air-water interface. Biochim Biophys Acta (1968) 3.35
Scavenger receptor BI promotes high density lipoprotein-mediated cellular cholesterol efflux. J Biol Chem (1997) 2.95
Cellular cholesterol efflux mediated by cyclodextrins. Demonstration Of kinetic pools and mechanism of efflux. J Biol Chem (1996) 2.93
Oral administration of an Apo A-I mimetic Peptide synthesized from D-amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterol. Circulation (2002) 2.91
Oral D-4F causes formation of pre-beta high-density lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice. Circulation (2004) 2.62
Cell cholesterol efflux: integration of old and new observations provides new insights. J Lipid Res (1999) 2.61
Electrocardiographic detection of left ventricular hypertrophy: development and prospective validation of improved criteria. J Am Coll Cardiol (1985) 2.50
Quality improvement in acute stroke: the New York State Stroke Center Designation Project. Neurology (2006) 2.40
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport. Proc Natl Acad Sci U S A (2004) 2.39
Apolipoprotein A-I mimetic peptides. Arterioscler Thromb Vasc Biol (2005) 2.33
Anti-inflammatory apoA-I-mimetic peptides bind oxidized lipids with much higher affinity than human apoA-I. J Lipid Res (2008) 2.27
Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3. J Lipid Res (2000) 2.22
Molecular interactions in mixed lecithin systems. Biochim Biophys Acta (1970) 2.21
Apolipoprotein E mimetic is more effective than apolipoprotein A-I mimetic in reducing lesion formation in older female apo E null mice. Atherosclerosis (2012) 2.19
Effects of increasing hydrophobicity on the physical-chemical and biological properties of a class A amphipathic helical peptide. J Lipid Res (2001) 2.11
Mechanisms and consequences of cellular cholesterol exchange and transfer. Biochim Biophys Acta (1987) 2.08
Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1. J Lipid Res (2000) 2.05
Differences in stability among the human apolipoprotein E isoforms determined by the amino-terminal domain. Biochemistry (2000) 2.01
Ketoconazole blocks testosterone synthesis. Arch Intern Med (1982) 2.01
D-4F and statins synergize to render HDL antiinflammatory in mice and monkeys and cause lesion regression in old apolipoprotein E-null mice. Arterioscler Thromb Vasc Biol (2005) 1.99
Lipoprotein inflammatory properties and serum amyloid A levels but not cholesterol levels predict lesion area in cholesterol-fed rabbits. J Lipid Res (2007) 1.96
Concern Crystal structure of human apolipoprotein A-I: insights into its protective effect against cardiovascular diseases. Proc Natl Acad Sci U S A (2006) 1.92
Studies of synthetic peptide analogs of the amphipathic helix. Structure of complexes with dimyristoyl phosphatidylcholine. J Biol Chem (1985) 1.89
The amphipathic alpha helix: a multifunctional structural motif in plasma apolipoproteins. Adv Protein Chem (1994) 1.89
The physical properties of an effective lung surfactant. Biochim Biophys Acta (1979) 1.85
Mechanism of cholesterol and phosphatidylcholine exchange or transfer between unilamellar vesicles. Biochemistry (1981) 1.84
A sensitive and convenient method for lipoprotein profile analysis of individual mouse plasma samples. J Lipid Res (2000) 1.83
Structural models of human apolipoprotein A-I: a critical analysis and review. Biochim Biophys Acta (2001) 1.80
Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases. Mol Cell Biol (1998) 1.79
Influence of molecular packing and phospholipid type on rates of cholesterol exchange. Biochemistry (1988) 1.75
The role of dysfunctional HDL in atherosclerosis. J Lipid Res (2008) 1.73
High density lipoprotein phospholipid composition is a major determinant of the bi-directional flux and net movement of cellular free cholesterol mediated by scavenger receptor BI. J Biol Chem (2000) 1.71
Apolipoprotein A-I (apoA-I) and apoA-I mimetic peptides inhibit tumor development in a mouse model of ovarian cancer. Proc Natl Acad Sci U S A (2010) 1.71
Cholesterol transport between cells and high-density lipoproteins. Biochim Biophys Acta (1991) 1.62
Mechanism of ion escape from phosphatidylcholine and phosphatidylserine single bilayer vesicles. Biochemistry (1973) 1.59
Only the two end helixes of eight tandem amphipathic helical domains of human apo A-I have significant lipid affinity. Implications for HDL assembly. Arterioscler Thromb Vasc Biol (1996) 1.55
Computer programs to identify and classify amphipathic alpha helical domains. J Lipid Res (1992) 1.54
Membrane interactions of synthetic peptides corresponding to amphipathic helical segments of the human immunodeficiency virus type-1 envelope glycoprotein. J Biol Chem (1992) 1.53
A new synthetic class A amphipathic peptide analogue protects mice from diet-induced atherosclerosis. J Lipid Res (2001) 1.53
Cytosolic domain of the human immunodeficiency virus envelope glycoproteins binds to calmodulin and inhibits calmodulin-regulated proteins. J Biol Chem (1993) 1.50
Cyclodextrins as catalysts for the removal of cholesterol from macrophage foam cells. J Clin Invest (1997) 1.50
Two apolipoprotein E mimetic peptides with similar cholesterol reducing properties exhibit differential atheroprotective effects in LDL-R null mice. Atherosclerosis (2012) 1.50
Inactivation of endothelial derived relaxing factor by oxidized lipoproteins. J Clin Invest (1992) 1.49
The inter- and intra-molecular mixing of hydrocarbon chains in lecithin-water systems. Chem Phys Lipids (1972) 1.49
Mechanisms for the modulation of membrane bilayer properties by amphipathic helical peptides. Biopolymers (1995) 1.48
Apolipoproteins, membrane cholesterol domains, and the regulation of cholesterol efflux. J Lipid Res (1992) 1.45
Arg123-Tyr166 domain of human ApoA-I is critical for HDL-mediated inhibition of macrophage homing and early atherosclerosis in mice. Arterioscler Thromb Vasc Biol (2001) 1.41
Structure and function of HDL mimetics. Arterioscler Thromb Vasc Biol (2009) 1.40
Plasma concentrations of inflammatory cytokines rise rapidly during ECMO-related SIRS due to the release of preformed stores in the intestine. Lab Invest (2009) 1.40
Interactions of synthetic peptide analogs of the class A amphipathic helix with lipids. Evidence for the snorkel hypothesis. J Biol Chem (1994) 1.39
Scavenger receptor class B type I as a mediator of cellular cholesterol efflux to lipoproteins and phospholipid acceptors. J Biol Chem (1998) 1.39
Efflux of cholesterol from different cellular pools. Biochemistry (2000) 1.37
A novel method for oral delivery of apolipoprotein mimetic peptides synthesized from all L-amino acids. J Lipid Res (2009) 1.37
Influenza infection promotes macrophage traffic into arteries of mice that is prevented by D-4F, an apolipoprotein A-I mimetic peptide. Circulation (2002) 1.37
On-site physician staffing in a community hospital intensive care unit. Impact on test and procedure use and on patient outcome. JAMA (1984) 1.37
Identification of a receptor mediating absorption of dietary cholesterol in the intestine. Biochemistry (1998) 1.37
Double belt structure of discoidal high density lipoproteins: molecular basis for size heterogeneity. J Mol Biol (2004) 1.36
The charge and structural stability of apolipoprotein A-I in discoidal and spherical recombinant high density lipoprotein particles. J Biol Chem (1992) 1.35
Inhibition of lipopolysaccharide-induced inflammatory responses by an apolipoprotein AI mimetic peptide. Circ Res (2005) 1.35
Effect of muscle glycogen depletion on in vivo insulin action in man. J Clin Invest (1983) 1.35
Scavenger receptor class B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells. Proc Natl Acad Sci U S A (1997) 1.34
Apolipoprotein A-I mimetic peptides and their role in atherosclerosis prevention. Nat Clin Pract Cardiovasc Med (2006) 1.33
Profile of endothelial and leukocyte activation in Fabry patients. Ann Neurol (2000) 1.32
Monolayer characteristics of some 1,2-diacyl, I-alkyl-2-acyl and 1,2-dialkyl phospholipids at the air-water interface. Biochim Biophys Acta (1971) 1.31
Lipid binding-induced conformational change in human apolipoprotein E. Evidence for two lipid-bound states on spherical particles. J Biol Chem (2001) 1.31
Janus kinase 2 modulates the lipid-removing but not protein-stabilizing interactions of amphipathic helices with ABCA1. J Lipid Res (2005) 1.30
Nuclear magnetic resonance study of lecithin-cholesterol interactions. J Mol Biol (1972) 1.28
Conformation of the lecithin polar group in charged vesicles. Nature (1976) 1.28
Bioactivity of peptide analogs of the neutrophil chemoattractant, N-acetyl-proline-glycine-proline. Invest Ophthalmol Vis Sci (1999) 1.28
Effect of indole-3-acetic acid on the synthesis of cyclic 3'-5' adenosine phosphate by Bengal gram seeds. Biochem Biophys Res Commun (1971) 1.27
Influence of apoE domain structure and polymorphism on the kinetics of phospholipid vesicle solubilization. J Lipid Res (2002) 1.27
Scavenger receptor BI (SR-BI) mediates free cholesterol flux independently of HDL tethering to the cell surface. J Lipid Res (1999) 1.27
Synthetic amphipathic helical peptides that mimic apolipoprotein A-I in clearing cellular cholesterol. J Clin Invest (1994) 1.26
Effects of intracellular free cholesterol accumulation on macrophage viability: a model for foam cell death. Arterioscler Thromb Vasc Biol (1998) 1.26
Truncation of the amino terminus of human apolipoprotein A-I substantially alters only the lipid-free conformation. Biochemistry (1997) 1.25
Mixed monolayers of phospholipids and cholesterol. Biochim Biophys Acta (1969) 1.25
Efflux of cellular cholesterol and phospholipid to lipid-free apolipoproteins and class A amphipathic peptides. Biochemistry (1995) 1.25
Mechanism of cholesterol efflux from cells. Effects of acceptor structure and concentration. J Biol Chem (1982) 1.24