An essential contribution by IFN-gamma to CD8+ T cell-mediated rejection of pancreatic islet allografts.

PubWeight™: 0.96‹?› | Rank: Top 15%

🔗 View Article (PMID 10861058)

Published in J Immunol on July 01, 2000

Authors

A S Diamond1, R G Gill

Author Affiliations

1: Department of Immunology and Medicine, Childhood Diabetes, University of Colorado Health Sciences Center, Denver 80262, USA.

Articles citing this

CD103 expression is required for destruction of pancreatic islet allografts by CD8(+) T cells. J Exp Med (2002) 1.16

Induction of tolerance to cardiac allografts using donor splenocytes engineered to display on their surface an exogenous fas ligand protein. J Immunol (2008) 0.97

IFN-gamma dictates allograft fate via opposing effects on the graft and on recipient CD8 T cell responses. J Immunol (2009) 0.93

TGFβ-dependent expression of PD-1 and PD-L1 controls CD8(+) T cell anergy in transplant tolerance. Elife (2016) 0.89

Alloreactive (CD4-Independent) CD8+ T cells jeopardize long-term survival of intrahepatic islet allografts. Am J Transplant (2008) 0.87

Cytotoxic effector function of CD4-independent, CD8(+) T cells is mediated by TNF-α/TNFR. Transplantation (2012) 0.85

CD8+ T cells negatively regulate IL-4-dependent, IgG1-dominant posttransplant alloantibody production. J Immunol (2010) 0.84

The effects of tolerance on allograft damage caused by the innate immune system. Transplantation (2008) 0.79

T-bet Regulates Natural Regulatory T Cell Afferent Lymphatic Migration and Suppressive Function. J Immunol (2016) 0.78

Interferon Gamma and Contact-dependent Cytotoxicity Are Each Rate Limiting for Natural Killer Cell-Mediated Antibody-dependent Chronic Rejection. Am J Transplant (2016) 0.77

Targeting CD8 T-Cell Metabolism in Transplantation. Front Immunol (2015) 0.77

Direct and indirect allograft recognition: pathways dictating graft rejection mechanisms. Curr Opin Organ Transplant (2016) 0.76

Adoptive transfer of tracer alloreactive CD4(+) TCR-transgenic T cells alters the endogenous immune response to an allograft. Am J Transplant (2016) 0.76

Evolving Approaches in the Identification of Allograft-reactive T and B Cells in Mice and Humans. Transplantation (2017) 0.75

Successful Treatment of T Cell-Mediated Acute Rejection with Delayed CTLA4-Ig in Mice. Front Immunol (2017) 0.75

Articles by these authors

Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice. Eur J Immunol (1995) 3.18

Analysis of the spontaneous T cell response to insulin in NOD mice. J Autoimmun (1994) 1.38

The use of Lassa fever convalescent plasma in Nigeria. Trans R Soc Trop Med Hyg (1984) 1.31

CD4 T cell-mediated cardiac allograft rejection requires donor but not host MHC class II. J Clin Invest (2000) 1.30

Initial results of screening of nondiabetic organ donors for expression of islet autoantibodies. J Clin Endocrinol Metab (2006) 1.27

LFA-1 (CD11a) as a therapeutic target. Am J Transplant (2006) 1.20

Autoimmune diabetes in NOD mouse is L3T4 T-lymphocyte dependent. Diabetes (1987) 1.17

Anti-LFA-1 therapy induces long-term islet allograft acceptance in the absence of IFN-gamma or IL-4. J Immunol (2000) 1.16

Evidence of recurrent autoimmunity in human allogeneic islet transplantation. Transplantation (1996) 1.08

The role of CD4+ and CD8+ T cells in the destruction of islet grafts by spontaneously diabetic mice. Proc Natl Acad Sci U S A (1991) 1.05

T lymphocyte indifference to extrathymic islet allografts. J Immunol (1996) 0.92

Islet allograft rejection by contact-dependent CD8+ T cells: perforin and FasL play alternate but obligatory roles. Am J Transplant (2007) 0.90

Facilitation of specific tolerance induction in adult mice by RS-61443. Transplantation (1992) 0.89

Autoimmune islet damage mediated by insulin-specific T cells. Transplant Proc (1997) 0.87

Dominant negative mutant forms of the cAMP response element binding protein induce apoptosis and decrease the anti-apoptotic action of growth factors in human islets. Diabetologia (2007) 0.86

Both innate and adaptive major histocompatibility complex class I-dependent immunity impair long-term islet xenograft survival. Transplant Proc (2008) 0.84

Studies on the two-signal model for T cell activation in vivo. Transplant Proc (1987) 0.84

Donor IFN-gamma receptors are critical for acute CD4(+) T cell-mediated cardiac allograft rejection. J Immunol (2001) 0.82

Prevention of rejection by treatment of the graft: an overview. Prog Clin Biol Res (1986) 0.81

Establishment of islet-specific T-cell lines and clones from islet isografts placed in spontaneously diabetic NOD mice. J Autoimmun (1993) 0.81

Donor antigen-presenting cell-independent rejection of islet xenografts. Transplantation (1995) 0.81

Role of the L3T4+ T cell in allograft rejection. J Immunol (1987) 0.81

Cellular immune response to phogrin in the NOD mouse: cloned T-cells cause destruction of islet transplants. Diabetes (1999) 0.80

alpha4 integrin in islet allograft rejection. Transplantation (2001) 0.80

Tissue immunogenicity: the role of MHC antigen and the lymphocyte costimulator B7-1. J Immunol (1996) 0.79

The basis of immunogenicity of endocrine allografts. Crit Rev Immunol (2001) 0.79

Tolerance to antigen-presenting cell-depleted islet allografts is CD4 T cell dependent. J Immunol (1999) 0.79

"Indirect" acute islet allograft destruction in nonobese diabetic mice is independent of donor major histocompatibility complex and requires host B lymphocytes. Transplant Proc (2008) 0.79

The maintenance of self-tolerance. Immunol Cell Biol (1993) 0.78

Tolerance induction in adult animals: comparison of RS-61443 and anti-CD4 treatment. Transplant Proc (1991) 0.78

Prolongation of islet allograft survival with an antibody to vascular cell adhesion molecule 1. Surgery (1995) 0.78

Bioartificial organs and acceptable risk. Nat Biotechnol (1999) 0.78

CD4 T cells acutely reject cardiac allografts via direct donor recognition. Transplant Proc (1999) 0.77

Role of lymphokine in islet allograft rejection. Transplantation (1990) 0.77

Tolerance induction to cultured islet allografts. I. Characterization of the tolerant state. Transplantation (1994) 0.77

A major role for host MHC class I antigen presentation for promoting islet allograft survival. Transplant Proc (2004) 0.77

An orchestrated dance between differing regulatory T cell phenotypes in allograft tolerance. Am J Transplant (2013) 0.75

Prolongation of cardiac allograft survival by a novel population of autologous CD117+ bone marrow-derived progenitor cells. Am J Transplant (2010) 0.75

Just how stable is allograft tolerance? Am J Transplant (2010) 0.75

Mechanism of self-tolerance to endocrine tissue. Springer Semin Immunopathol (1993) 0.75

Cyclosporine-induced tolerance requires antigens capable of initiating an immune response. J Immunol (1987) 0.75

A quantitative analysis of antigen-triggered lymphokine production by activated T cells. J Immunol (1987) 0.75

Xenoreactive T-cell lines initiate pancreatic islet graft destruction in vivo. Transplant Proc (1993) 0.75

Distinct requirements for host CD80/CD86 costimulatory molecules in cardiac versus islet rejection. Transplant Proc (2004) 0.75

Prevention of autoimmune diabetes in the BB rat by intrathymic islet transplantation at birth. J Endocrinol Invest (1995) 0.75

The 2C T-cell transgenic mouse: an in vivo model of allospecific cytotoxic T-cell activation and homing. Transplant Proc (1999) 0.75

Immunobiology of cardiac allograft and xenograft transplantation. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu (2001) 0.75

Nature of tolerance induction to peripheral (extrathymic) islet allografts. Transplant Proc (1994) 0.75

CD4 T cells and allograft rejection. Transplant Proc (1988) 0.75

Different roles for alpha 4-integrin/VCAM-1 and alpha 4/fibronectin interactions in allograft rejection. Transplant Proc (1999) 0.75

Role of gamma-interferon in islet allograft rejection: class I MHC antigen induction. Transplant Proc (1989) 0.75

Adoptive transfer of CD4 T-cell dependent allograft tolerance. Transplant Proc (1997) 0.75

Autoimmune destruction of islet grafts in the NOD mouse is resistant to 15-deoxyspergualin but sensitive to anti-CD4 antibody. J Surg Res (1996) 0.75

Tolerance induction to cultured islet allografts. II. The status of antidonor reactivity in tolerant animals. Transplantation (1994) 0.75