Induction of vascular endothelial growth factor in human astrocytes by lead. Involvement of a protein kinase C/activator protein-1 complex-dependent and hypoxia-inducible factor 1-independent signaling pathway.

PubWeight™: 1.15‹?› | Rank: Top 10%

🔗 View Article (PMID 10882716)

Published in J Biol Chem on September 08, 2000

Authors

M A Hossain1, C M Bouton, J Pevsner, J Laterra

Author Affiliations

1: Departments of Neurology, Neuroscience, and Oncology, The Johns Hopkins University School of Medicine and The Kennedy Krieger Research Institute, Baltimore, Maryland 21205, USA. hossain@kennedykrieger.org

Articles citing this

Host prostaglandin E(2)-EP3 signaling regulates tumor-associated angiogenesis and tumor growth. J Exp Med (2003) 1.69

Expression of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 (KDR/Flk-1) in ischemic skeletal muscle and its regeneration. Am J Pathol (2002) 1.62

Upregulated hypoxia inducible factor-1alpha and -2alpha pathway in rheumatoid arthritis and osteoarthritis. Arthritis Res Ther (2003) 1.20

Early lead exposure increases the leakage of the blood-cerebrospinal fluid barrier, in vitro. Hum Exp Toxicol (2007) 0.95

Effects of 12 metal ions on iron regulatory protein 1 (IRP-1) and hypoxia-inducible factor-1 alpha (HIF-1alpha) and HIF-regulated genes. Toxicol Appl Pharmacol (2006) 0.93

Scatter factor/hepatocyte growth factor stimulation of glioblastoma cell cycle progression through G(1) is c-Myc dependent and independent of p27 suppression, Cdk2 activation, or E2F1-dependent transcription. Mol Cell Biol (2002) 0.91

Progress in the application of DNA microarrays. Environ Health Perspect (2001) 0.90

Lead induces chondrogenesis and alters transforming growth factor-beta and bone morphogenetic protein signaling in mesenchymal cell populations. Environ Health Perspect (2007) 0.89

Heavy Metal Ion Regulation of Gene Expression: MECHANISMS BY WHICH LEAD INHIBITS OSTEOBLASTIC BONE-FORMING ACTIVITY THROUGH MODULATION OF THE Wnt/β-CATENIN SIGNALING PATHWAY. J Biol Chem (2015) 0.86

Functional genomics and metal metabolism. Genome Biol (2001) 0.85

Early chronic low-level lead exposure produces glomerular hypertrophy in young C57BL/6J mice. Toxicol Lett (2013) 0.79

Lead exposure stimulates VEGF expression in the spinal cord and extends survival in a mouse model of ALS. Neurobiol Dis (2009) 0.79

Effect of lead on ERK activity and the protective function of bFGF in rat primary culture astroglia. J Zhejiang Univ Sci B (2007) 0.75

Inhibition of beta-catenin signaling by Pb leads to incomplete fracture healing. J Orthop Res (2014) 0.75

Peripheral blood signatures of lead exposure. PLoS One (2011) 0.75

Matching target dose to target organ. F1000Res (2016) 0.75

Expression of calmodulin-related genes in lead-exposed mice. Interdiscip Toxicol (2015) 0.75

Articles by these authors

The biology of the mammalian Krüppel-like family of transcription factors. Int J Biochem Cell Biol (2001) 3.31

Postmortem brain abnormalities of the glutamate neurotransmitter system in autism. Neurology (2001) 2.49

Cell surface heparan sulfate mediates some adhesive responses to glycosaminoglycan-binding matrices, including fibronectin. J Cell Biol (1983) 2.35

Control of fusion pore dynamics during exocytosis by Munc18. Science (2001) 2.11

Regulation of CFTR chloride channels by syntaxin and Munc18 isoforms. Nature (1997) 1.98

Gene expression profiling in postmortem Rett Syndrome brain: differential gene expression and patient classification. Neurobiol Dis (2001) 1.59

Scatter factor/hepatocyte growth factor protects against cytotoxic death in human glioblastoma via phosphatidylinositol 3-kinase- and AKT-dependent pathways. Cancer Res (2000) 1.56

Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression. J Natl Cancer Inst (1999) 1.44

Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages. Mol Biol Cell (2000) 1.43

The three-dimensional structure of bovine odorant binding protein and its mechanism of odor recognition. Nat Struct Biol (1996) 1.41

Close and focal contact adhesions of fibroblasts to a fibronectin-containing matrix. Fed Proc (1985) 1.36

Glycosaminoglycans that bind cold-insoluble globulin in cell-substratum adhesion sites of murine fibroblasts. Proc Natl Acad Sci U S A (1980) 1.36

Regulation of Munc-18/syntaxin 1A interaction by cyclin-dependent kinase 5 in nerve endings. J Biol Chem (1998) 1.36

Isolation and characterization of an olfactory receptor protein for odorant pyrazines. Proc Natl Acad Sci U S A (1985) 1.34

Neurovirulent simian immunodeficiency virus replicates productively in endothelial cells of the central nervous system in vivo and in vitro. J Virol (1994) 1.33

Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition. Oncogene (2011) 1.33

Modulation of oncogenic potential by alternative gene use in human prostate cancer. Nat Med (1999) 1.26

Scatter factor promotes motility of human glioma and neuromicrovascular endothelial cells. Int J Cancer (1998) 1.26

DRAGON: Database Referencing of Array Genes Online. Bioinformatics (2000) 1.26

Association of three small GTP-binding proteins with cholinergic synaptic vesicles. FEBS Lett (1993) 1.26

Differences in hyaluronate binding to plasma and cell surface fibronectins. Requirement for aggregation. J Biol Chem (1982) 1.23

Stable association of presenilin derivatives and absence of presenilin interactions with APP. Neurobiol Dis (1998) 1.23

Human syntaxin 7: a Pep12p/Vps6p homologue implicated in vesicle trafficking to lysosomes. Gene (1997) 1.20

The expanding beta 4-galactosyltransferase gene family: messages from the databanks. Glycobiology (1998) 1.17

Scatter factor expression and regulation in human glial tumors. Int J Cancer (1996) 1.15

EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase. Oncogene (2012) 1.12

Scatter factor stimulates tumor growth and tumor angiogenesis in human breast cancers in the mammary fat pads of nude mice. Lab Invest (1997) 1.10

X-linked adrenoleukodystrophy: genes, mutations, and phenotypes. Neurochem Res (1999) 1.09

Neurobiology of Rett syndrome: a genetic disorder of synapse development. Brain Dev (2001) 1.09

Contact formation by fibroblasts adhering to heparan sulfate-binding substrata (fibronectin or platelet factor 4). Exp Cell Res (1983) 1.08

HGF/SF in angiogenesis. Ciba Found Symp (1997) 1.06

Signaling pathways in the induction of c-met receptor expression by its ligand scatter factor/hepatocyte growth factor in human glioblastoma. J Neurochem (2001) 1.02

Scatter factor/hepatocyte growth factor (SF/HGF) content and function in human gliomas. Int J Dev Neurosci (1999) 1.02

A hammerhead ribozyme suppresses expression of hepatocyte growth factor/scatter factor receptor c-MET and reduces migration and invasiveness of breast cancer cells. Clin Cancer Res (2001) 0.99

X-ray microbeams: Tumor therapy and central nervous system research. Nucl Instrum Methods Phys Res A (2005) 0.98

Squalamine inhibits angiogenesis and solid tumor growth in vivo and perturbs embryonic vasculature. Cancer Res (1998) 0.98

Odorant-binding protein: localization to nasal glands and secretions. Proc Natl Acad Sci U S A (1986) 0.97

Endothelial differentiation in intracerebral and subcutaneous experimental gliomas. Brain Res (1994) 0.96

Heparan sulphate proteoglycan as mediator of some adhesive responses and cytoskeletal reorganization of cells on fibronectin matrices: independent versus cooperative functions. Ciba Found Symp (1986) 0.96

The glucose transporter and blood-brain barrier of human brain tumors. Ann Neurol (1990) 0.95

Dexamethasone reduces vascular density and plasminogen activator activity in 9L rat brain tumors. Brain Res (1993) 0.93

Abnormal renal mobility--an indication for surgical intervention. Urol Int (1989) 0.91

High throughput analysis of gene expression in the human brain. J Neurosci Res (2000) 0.91

Synaptotagmin I is a molecular target for lead. J Neurochem (2001) 0.89

5'-nucleotidase from the electric ray electric lobe. Primary structure and relation to mammalian and procaryotic enzymes. Eur J Biochem (1991) 0.89

Detection of endogenous biotin in various tissues: novel functions in the hippocampus and implications for its use in avidin-biotin technology. Cell Tissue Res (1999) 0.89

Human FGF-1 gene delivery protects against quinolinate-induced striatal and hippocampal injury in neonatal rats. Eur J Neurosci (1998) 0.88

Molecular mechanisms of olfaction. J Biol Chem (1988) 0.87

Naturally occurring free D-aspartate is a nuclear component of cells in the mammalian hypothalamo-neurohypophyseal system. Neuroscience (2002) 0.86

Glioma inhibition by HGF/NK2, an antagonist of scatter factor/hepatocyte growth factor. Biochem Biophys Res Commun (2000) 0.86

Vascular differentiation and glucose transporter expression in rat gliomas: effects of steroids. Ann Neurol (1992) 0.86

Vascular expression of glucose transporter in experimental brain neoplasms. Am J Pathol (1992) 0.85

Unique pharmacological actions of atypical neuroleptic quetiapine: possible role in cell cycle/fate control. Transl Psychiatry (2013) 0.83

Selective endothelial growth inhibition by tetracyclines that inhibit collagenase. Biochem Biophys Res Commun (1992) 0.83

Steroid inhibition of neural microvessel morphogenesis in vitro: receptor mediation and astroglial dependence. J Neurochem (1992) 0.83

A synaptic vesicle specific GTP-binding protein from ray electric organ. Brain Res Mol Brain Res (1991) 0.83

Dexamethasone inhibits glioma-induced formation of capillary like structures in vitro and angiogenesis in vivo. Klin Padiatr (1997) 0.83

Effects of lead on gene expression. Neurotoxicology (2000) 0.82

IL-10 gene transfer to intracranial 9L glioma: tumor inhibition and cooperation with IL-2. J Neuroimmunol (1998) 0.81

Alterations in blood-brain barrier glucose transport in SIV-infected macaques. J Neurovirol (1999) 0.81

Microarray analysis of differential gene expression in lead-exposed astrocytes. Toxicol Appl Pharmacol (2001) 0.80

Molecular mechanisms of olfaction. Trends Neurosci (1989) 0.80

Regulation of rat magnocellular neurosecretory system by D-aspartate: evidence for biological role(s) of a naturally occurring free D-amino acid in mammals. J Endocrinol (2000) 0.80

Regulation of angiogenesis in malignant gliomas. EXS (1997) 0.79

Parametric influences on catalepsy. Psychopharmacology (Berl) (1984) 0.79

Scatter factor/hepatocyte growth factor gene transfer increases rat blood-glioma barrier permeability. Brain Res (1999) 0.79

Effect of postnatal age and clinical status of newborn infants on bilirubin-binding capacity. Biol Neonate (1977) 0.79

Endothelial cell-based cytokine gene delivery inhibits 9L glioma growth in vivo. Brain Res (1996) 0.79

Endothelial cell implantation and survival within experimental gliomas. Proc Natl Acad Sci U S A (1994) 0.78

Human very long-chain acyl-CoA synthetase and two human homologs: initial characterization and relationship to fatty acid transport protein. Prostaglandins Leukot Essent Fatty Acids (2000) 0.78

Hepatocyte growth factor/scatter factor blocks the mitochondrial pathway of apoptosis signaling in breast cancer cells. J Biol Chem (2001) 0.78

Emerging technologies for large-scale screening of human tissues and fluids in the study of severe psychiatric disease. Int J Neuropsychopharmacol (2001) 0.77

Delivery of human fibroblast growth factor-1 gene to brain by modified rat brain endothelial cells. J Neurochem (1996) 0.77

The abnormal regulation of gene expression in autistic brain tissue. J Autism Dev Disord (2001) 0.77

Assessment of neural cell adhesion molecule (NCAM) in autistic serum and postmortem brain. J Autism Dev Disord (2001) 0.77

Development of endogenous beta-galactosidase and autofluorescence in rat brain microvessels: implications for cell tracking and gene transfer studies. J Histochem Cytochem (1994) 0.76

Spinal meningioma causing diffuse leptomeningeal enhancement. Neurology (2003) 0.76

Modulation of serine proteinases and metalloproteinases during morphogenic glial-endothelial interactions. J Neurochem (1996) 0.75

Concerns about universal hepatitis B immunization. Am Fam Physician (1994) 0.75

Fetal methylazoxymethanol acetate-induced lesions cause reductions in dopamine receptor-mediated catalepsy and stereotypy. Neuropharmacology (1985) 0.75

Hood lab investigation. Science (1991) 0.75