Published in Nature on November 18, 1976
Lengths of chromosomal segments conserved since divergence of man and mouse. Proc Natl Acad Sci U S A (1984) 6.26
Inherited structural polymorphism of the fourth component of human complement. Proc Natl Acad Sci U S A (1980) 3.97
Two HLA-linked loci controlling the fourth component of human complement. Proc Natl Acad Sci U S A (1978) 3.05
The isolation and structure of C4, the fourth component of human complement. Biochem J (1977) 2.61
Human C4-binding protein. I. Isolation and characterization. J Exp Med (1978) 2.60
Assignment of the structural gene for the third component of human complement to chromosome 19. Proc Natl Acad Sci U S A (1982) 2.00
Structural basis of the polymorphism of human complement components C4A and C4B: gene size, reactivity and antigenicity. EMBO J (1986) 1.54
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Human C4 haplotypes with duplicated C4A or C4B. Am J Hum Genet (1984) 1.24
Chemical characterization of murine Ia alloantigens determined by the i-E/i-C subregions of the H-2 complex. Proc Natl Acad Sci U S A (1977) 1.09
Great genotypic and phenotypic diversities associated with copy-number variations of complement C4 and RP-C4-CYP21-TNX (RCCX) modules: a comparison of Asian-Indian and European American populations. Mol Immunol (2009) 1.07
Evidence for linkage between the loci coding for the binding protein for the fourth component of human complement (C4BP) and for the C3b/C4b receptor. Proc Natl Acad Sci U S A (1984) 0.99
Murine binding protein of the fourth component of complement: structural polymorphism and its linkage to the major histocompatibility complex. Proc Natl Acad Sci U S A (1981) 0.88
Studies on the C2-deficiency gene in man. Immunology (1980) 0.87
Linkage studies in hereditary angio-oedema. J Med Genet (1979) 0.81
Comparative map for mice and humans. Mamm Genome (1991) 0.81
Association of low C2 and C4 serum levels with the HLA-DW2 allele in healthy individuals. J Exp Med (1978) 0.79
The human genes for complement components 6 (C6) and 9 (C9) are closely linked on chromosome 5. J Med Genet (1991) 0.78
HLA-linked C2 deficiency in a Dutch patient with systemic lupus erythematosus. J Clin Pathol (1979) 0.75
Evidence that the fourth component of complement (C4) is carried on a high proportion of normal guinea-pig B lymphocytes. Immunology (1981) 0.75
Report of the Committee on the Genetic Constitution of Chromosomes 13, 14, 15 and 16. Cytogenet Cell Genet (1985) 6.87
International Nosology of Heritable Disorders of Connective Tissue, Berlin, 1986. Am J Med Genet (1988) 4.84
Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer. J Exp Med (1989) 4.30
Identification of the gene altered in Berardinelli-Seip congenital lipodystrophy on chromosome 11q13. Nat Genet (2001) 3.50
Autosomal linkage between the Gm and Pi loci in man. Ann Hum Genet (1972) 3.34
Gliadin-specific, HLA-DQ(alpha 1*0501,beta 1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients. J Exp Med (1993) 3.10
Genes and languages in Europe: an analysis of mitochondrial lineages. Genome Res (1995) 2.93
HLA susceptibility genes in celiac disease: genetic mapping and role in pathogenesis. Gastroenterology (1993) 2.72
HLA-D restriction of the macrophage-dependent response of immune human T lymphocytes to PPD in vitro: inhibition by anti-HLA-DR antisera. Scand J Immunol (1978) 2.70
Statement on the nomenclature of human C4 allotypes. Immunobiology (1983) 2.66
HLA-DR-like antigens in the epithelium of the human small intestine. Scand J Immunol (1980) 2.58
Osteosarcoma and retinoblastoma: a shared chromosomal mechanism revealing recessive predisposition. Proc Natl Acad Sci U S A (1985) 2.44
High voltage agarose gel electrophoresis in the study of C 3 polymorphism. Vox Sang (1970) 2.43
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The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene. Am J Hum Genet (1999) 2.17
Studies on human epidermal Langerhans cells. I. Allo-activating and antigen-presenting capacity. Scand J Immunol (1980) 2.09
[Genetic diagnostic test for hemochromatosis]. Tidsskr Nor Laegeforen (1998) 2.02
HLA antigens and rheumatoid arthritis. Association between HLA-DRw4 positivity and IgM rheumatoid factor production. Arthritis Rheum (1980) 1.97
Interferon-gamma enhances expression of secretory component, the epithelial receptor for polymeric immunoglobulins. J Immunol (1987) 1.85
Identification of a gliadin T-cell epitope in coeliac disease: general importance of gliadin deamidation for intestinal T-cell recognition. Scand J Immunol (1998) 1.85
Macrophage-dependent response of immune human T lymphocytes to PPD in vitro. Influence of HLA-D histocompatibility. Scand J Immunol (1977) 1.84
Genotype-phenotype relationships in Berardinelli-Seip congenital lipodystrophy. J Med Genet (2002) 1.84
Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis. Tissue Antigens (2007) 1.77
HLA class I and II typing using cells positively selected from blood by immunomagnetic isolation--a fast and reliable technique. Tissue Antigens (1986) 1.67
Relation between HLA-DR-like antigens and secretory component (SC) in jejunal epithelium of patients with coeliac disease or dermatitis herpetiformis. Clin Exp Immunol (1981) 1.66
Y-chromosomal microsatellite mutation rates: differences in mutation rate between and within loci. Hum Mutat (2004) 1.60
The peptide binding motif of the disease associated HLA-DQ (alpha 1* 0501, beta 1* 0201) molecule. Eur J Immunol (1996) 1.53
HLA antigens and immunoregulatory T cells in ulcerative colitis associated with hepatobiliary disease. Scand J Gastroenterol (1982) 1.53
Genotype effects and epistasis in type 1 diabetes and HLA-DQ trans dimer associations with disease. Genes Immun (2004) 1.53
T cells from the small intestinal mucosa of a DR4, DQ7/DR4, DQ8 celiac disease patient preferentially recognize gliadin when presented by DQ8. Hum Immunol (1994) 1.52
Antigen presentation by vascular endothelial cells and epidermal Langerhans cells: the role of HLA-DR. Immunol Rev (1982) 1.51
The human mixed lymphocyte-endothelium culture interaction. Transplantation (1975) 1.50
Report of the Committee on the Genetic Constitution of Chromosomes 5 and 6. Cytogenet Cell Genet (1985) 1.47
Paternity Testing Commission of the International Society of Forensic Genetics. Recommendations on genetic investigations in paternity cases. Int J Legal Med (2003) 1.46
CD4+ T cells with specific reactivity against astrovirus isolated from normal human small intestine. Gastroenterology (1998) 1.45
Antigen-presenting properties of human vascular endothelial cells. J Exp Med (1980) 1.43
Strong association between the HLA-Dw3-related B cell alloantigen -DRw3 and coeliac disease. Scand J Gastroenterol (1978) 1.43
HLA-D region molecules restrict proliferative T cell responses to antigen. Immunol Rev (1982) 1.42
The locus for apolipoprotein E (apoE) is linked to the complement component C3 (C3) locus on chromosome 19 in man. Hum Genet (1982) 1.40
[Serotonin syndrome with fatal outcome caused by selective serotonin reuptake inhibitors]. Tidsskr Nor Laegeforen (1999) 1.39
The genetic polymorphism of the fourth component of human complement: methodological aspects and a presentation of linkage and association data relevant to its localization in the HLA region. J Exp Med (1977) 1.38
Isolation of pure functionally active CD8+ T cells. Positive selection with monoclonal antibodies directly conjugated to monosized magnetic microspheres. J Immunol Methods (1986) 1.38
DNA commission of the international society for forensic genetics: guidelines for mitochondrial DNA typing. Forensic Sci Int (2000) 1.37
T cells recognize a peptide derived from alpha-gliadin presented by the celiac disease-associated HLA-DQ (alpha 1*0501, beta 1*0201) heterodimer. Hum Immunol (1994) 1.37
HLA class II haplotypes in primary sclerosing cholangitis patients from five European populations. Tissue Antigens (1999) 1.35
Induction of various HLA class II molecules in a human colonic adenocarcinoma cell line. Scand J Immunol (1987) 1.33
In vitro assay of cell-mediated immunity: the inhibition of migration of sensitized human lymphocytes by HL-A antigens. Clin Exp Immunol (1970) 1.32
Scandiatransplant: preliminary report of a kidney exchange program. Transplant Proc (1971) 1.32
Report of the committee on the genetic constitution of chromosomes 13, 14, 15 amd 16. Cytogenet Cell Genet (1987) 1.32
Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases. Genes Immun (2005) 1.32
Evidence by allelic association-dependent methods for a type 1 diabetes polygene (IDDM6) on chromosome 18q21. Hum Mol Genet (1997) 1.32
Humoral immune system activity in inflammatory bowel disease. Scand J Gastroenterol (1975) 1.31
On the HLA-DQ(alpha 1*0501, beta 1*0201)-associated susceptibility in celiac disease: a possible gene dosage effect of DQB1*0201. Tissue Antigens (1993) 1.31
The relation of parental sex and age to recombination in the HL-A system. Hum Hered (1973) 1.30
Very close linkage between HLA-B and Bf inferred from allelic association. Nature (1977) 1.30
DNA commission of the International Society of Forensic Genetics: recommendations on forensic analysis using Y-chromosome STRs. Int J Legal Med (2001) 1.28
Immunohistochemical and mutation analyses demonstrate that procollagen VII is processed to collagen VII through removal of the NC-2 domain. J Cell Biol (1995) 1.27
Human transplantation antigens. Appendix: current methods in histocompatibility testing. Transplant Rev (1969) 1.27
The human major histocompatibility system. Transplant Rev (1974) 1.25
Direct immunomagnetic quantification of lymphocyte subsets in blood. Clin Exp Immunol (1988) 1.24
A gene telomeric of the HLA class I region is involved in predisposition to both type 1 diabetes and coeliac disease. Tissue Antigens (1999) 1.22
HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection. Diabetes (1997) 1.22
Intraabdominal pressure and trunk muscle activity during lifting--effect of abdominal muscle training in healthy subjects. Scand J Rehabil Med (1983) 1.22
HL-A antigens and susceptibility to diseases. A study of patients with acute lymphoblastic leukaemia, Hodgkin's disease, and childhood asthma. Tissue Antigens (1971) 1.22
Circulating conversion products of C3 in liver disease. Evidence for in vivo activation of the complement system. Clin Exp Immunol (1973) 1.22
Identification of a putative motif for binding of peptides to HLA-DQ2. Int Immunol (1996) 1.22
The association between rheumatoid arthritis and the HLA antigen DR4. Ann Rheum Dis (1983) 1.21
Evidence of at least two type 1 diabetes susceptibility genes in the HLA complex distinct from HLA-DQB1, -DQA1 and -DRB1. Genes Immun (2003) 1.19
Cell specific and common antigens on human granulocytes and lymphocytes demonstrated with cytotoxic hetero-antibodies. Vox Sang (1967) 1.19
Proliferative human T cell responses to Chlamydia trachomatis in vitro. Acta Pathol Microbiol Immunol Scand C (1983) 1.19
The C8A and C8B loci are closely linked on chromosome 1. Ann Hum Genet (1986) 1.19
DNA Commission of the International Society for Forensic Genetics: guidelines for mitochondrial DNA typing. Int J Legal Med (2000) 1.18
HLA-DR and -DQ genotypes of celiac disease patients serologically typed to be non-DR3 or non-DR5/7. Hum Immunol (1992) 1.17
Heterogeneous reactivity patterns of HLA-DQ-restricted, small intestinal T-cell clones from patients with celiac disease. Gastroenterology (1997) 1.17
Vaccination with mutant ras peptides and induction of T-cell responsiveness in pancreatic carcinoma patients carrying the corresponding RAS mutation. Lancet (1995) 1.17
Complement and cell-mediated specific destruction of human endothelial cells treated with anti-DRw antisera. Transplant Proc (1979) 1.17
Sixteen types of epidermolysis bullosa. On the clinical discrimination, therapy and prenatal diagnosis. Acta Derm Venereol Suppl (Stockh) (1981) 1.16
Rga (Rodgers) and the HLA region: linkage and associations. Tissue Antigens (1976) 1.16
Expression of major histocompatibility complex class II subregion products by jejunal epithelium in patients with coeliac disease. Scand J Immunol (1987) 1.15
HLA DR antigens and gold toxicity. Ann Rheum Dis (1983) 1.14
Congenital ichthyosis: mutations in ichthyin are associated with specific structural abnormalities in the granular layer of epidermis. J Med Genet (2007) 1.13
Genetics of the Pi serum types. Family studies of the inherited variants of serum alpha-1-antitrypsin. Hum Hered (1969) 1.12
Distribution of HLA class II alleles among Norwegian Caucasians. Hum Immunol (1990) 1.12
Dermatitis herpetiformis and celiac disease are both primarily associated with the HLA-DQ (alpha 1*0501, beta 1*02) or the HLA-DQ (alpha 1*03, beta 1*0302) heterodimers. Tissue Antigens (1997) 1.11
Distribution of HLA-DRB1, -DQA1 and -DQB1 alleles and DQA1-DQB1 genotypes among Norwegian patients with insulin-dependent diabetes mellitus. Tissue Antigens (1991) 1.11
Assignment of the locus for ichthyosis prematurity syndrome to chromosome 9q33.3-34.13. J Med Genet (2004) 1.10
Influence of in vivo hydrocortisone on some human blood lymphocyte subpopulations. I. Effect on natural killer cell activity. Scand J Immunol (1981) 1.10
Fish as a source of exposure to mercury and selenium. Sci Total Environ (1992) 1.10
Cell mediated lympholysis: CML. a microplate technique requiring few target cells and employing a new method of supernatant collection. J Immunol Methods (1977) 1.10