Published in Oncogene on July 06, 2000
The Survivin saga goes in vivo. J Clin Invest (2001) 1.66
Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma. Br J Cancer (2002) 1.62
Nuclear or cytoplasmic expression of survivin: what is the significance? Int J Cancer (2005) 1.52
Elevated expressions of MMP7, TROP2, and survivin are associated with survival, disease recurrence, and liver metastasis of colon cancer. Int J Colorectal Dis (2009) 1.46
Expression of different survivin variants in gastric carcinomas: first clues to a role of survivin-2B in tumour progression. Br J Cancer (2002) 1.45
Neurotrophin p75 receptor (p75NTR) promotes endothelial cell apoptosis and inhibits angiogenesis: implications for diabetes-induced impaired neovascularization in ischemic limb muscles. Circ Res (2008) 1.29
Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation. Am J Pathol (2002) 1.24
CENP-F expression is associated with poor prognosis and chromosomal instability in patients with primary breast cancer. Int J Cancer (2007) 1.17
Tetra-O-methyl nordihydroguaiaretic acid induces growth arrest and cellular apoptosis by inhibiting Cdc2 and survivin expression. Proc Natl Acad Sci U S A (2004) 1.16
Impairment of glioma stem cell survival and growth by a novel inhibitor for Survivin-Ran protein complex. Clin Cancer Res (2012) 1.11
Silencing survivin splice variant 2B leads to antitumor activity in taxane--resistant ovarian cancer. Clin Cancer Res (2011) 1.03
Survivin monomer plays an essential role in apoptosis regulation. J Biol Chem (2011) 0.99
Effect of NF-kappaB, survivin, Bcl-2 and Caspase3 on apoptosis of gastric cancer cells induced by tumor necrosis factor related apoptosis inducing ligand. World J Gastroenterol (2004) 0.95
The other side of the coin: the tumor-suppressive aspect of oncogenes and the oncogenic aspect of tumor-suppressive genes, such as those along the CCND-CDK4/6-RB axis. Cell Cycle (2014) 0.94
Survivin and Tumorigenesis: Molecular Mechanisms and Therapeutic Strategies. J Cancer (2016) 0.93
TGF-β1 regulates cell fate during epithelial-mesenchymal transition by upregulating survivin. Cell Death Dis (2013) 0.91
Cellular localisation of survivin: impact on the prognosis in colorectal cancer. J Cancer Res Clin Oncol (2005) 0.90
Temporal and spatial patterns of expression of inhibitors of apoptosis in human placentas. Am J Pathol (2003) 0.90
Epstein-Barr virus oncoprotein LMP1 mediates survivin upregulation by p53 contributing to G1/S cell cycle progression in nasopharyngeal carcinoma. Int J Mol Med (2012) 0.88
Short hairpin RNA-mediated fibronectin knockdown delays tumor growth in a mouse glioma model. Neoplasia (2010) 0.88
Carminomycin I is an apoptosis inducer that targets the Golgi complex in clear cell renal carcinoma cells. Cancer Res (2011) 0.88
Transcriptional inhibition of p21WAF1/CIP1 gene (CDKN1) expression by survivin is at least partially p53-dependent: evidence for survivin acting as a transcription factor or co-factor. Biochem Biophys Res Commun (2012) 0.87
Genomic modeling of tumor onset and progression in a mouse model of aggressive human liver cancer. Carcinogenesis (2011) 0.86
Minocycline is cytoprotective in human trabecular meshwork cells and optic nerve head astrocytes by increasing expression of XIAP, survivin, and Bcl-2. Clin Ophthalmol (2010) 0.86
Effects and mechanism of downregulation of survivin expression by RNA interference on proliferation and apoptosis of lung cancer cells. Mol Med Rep (2012) 0.85
Survivin as a potential mediator to support autoreactive cell survival in myasthenia gravis: a human and animal model study. PLoS One (2014) 0.83
In vitro anti-cancer activity of chamaejasmenin B and neochamaejasmin C isolated from the root of Stellera chamaejasme L. Acta Pharmacol Sin (2012) 0.82
Pathways of proliferation: new targets to inhibit the growth of vascular smooth muscle cells. Circ Res (2008) 0.82
Identifying tumor cell growth inhibitors by combinatorial chemistry and zebrafish assays. PLoS One (2009) 0.81
Developmental expression of survivin during embryonic submandibular salivary gland development. BMC Dev Biol (2001) 0.81
Analysis of the expression levels of survivin and VEGF in patients with acute lymphoblastic leukemia. Exp Ther Med (2012) 0.81
Rational design of the survivin/CDK4 complex by combining protein-protein docking and molecular dynamics simulations. J Mol Model (2012) 0.80
The human immunodeficiency virus protease inhibitor ritonavir inhibits lung cancer cells, in part, by inhibition of survivin. J Thorac Oncol (2011) 0.80
Fluorescent carbon dots as an efficient siRNA nanocarrier for its interference therapy in gastric cancer cells. J Nanobiotechnology (2014) 0.80
Significance and relationship between DJ-1 gene and surviving gene expression in laryngeal carcinoma. Eur J Histochem (2011) 0.79
Rb1 loss modifies but does not initiate alveolar rhabdomyosarcoma. Skelet Muscle (2013) 0.77
EF24 inhibits tumor growth and metastasis via suppressing NF-kappaB dependent pathways in human cholangiocarcinoma. Sci Rep (2016) 0.75
Apoptosis and injuries of heavy ion beam and x-ray radiation on malignant melanoma cell. Exp Biol Med (Maywood) (2017) 0.75
Effects of survivin on angiogenesis in vivo and in vitro. Am J Transl Res (2016) 0.75
Immunohistochemical expression and serum level of survivin protein in colorectal cancer patients. Oncol Lett (2016) 0.75
Retracted Ophthalmic Combination of SurR9-C84A and Trichostatin-A Targeting Molecular Pathogenesis of Alkali Burn. Front Pharmacol (2016) 0.75
Small interfering RNA targeting of the survivin gene inhibits human tumor cell growth in vitro. Exp Ther Med (2017) 0.75
The Quantitative Estimation of the Fat-Soluble Factor. Biochem J (1921) 30.70
Whole genome sequencing of meticillin-resistant Staphylococcus aureus. Lancet (2001) 18.55
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase) Science (1996) 15.88
Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J Biol Chem (1996) 10.51
A new class of genetic element, staphylococcus cassette chromosome mec, encodes methicillin resistance in Staphylococcus aureus. Antimicrob Agents Chemother (2000) 9.84
The Differential Dialysis of the Antineuritic and the Antiscorbutic Factors. Biochem J (1921) 9.14
Identification of human herpesvirus-6 as a causal agent for exanthem subitum. Lancet (1988) 8.76
Characterization of avian H5N1 influenza viruses from poultry in Hong Kong. Virology (1998) 7.99
The emergence and evolution of methicillin-resistant Staphylococcus aureus. Trends Microbiol (2001) 7.73
Naltrexone in the treatment of alcohol dependence. Arch Gen Psychiatry (1992) 5.48
Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell (1994) 5.25
Biological heterogeneity, including systemic replication in mice, of H5N1 influenza A virus isolates from humans in Hong Kong. J Virol (1999) 5.21
Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. EMBO J (1996) 5.14
The epidemiology and iatrogenic transmission of hepatitis C virus in Egypt: a Bayesian coalescent approach. Mol Biol Evol (2003) 4.99
Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins. Science (1993) 4.64
T cell-specific loss of Pten leads to defects in central and peripheral tolerance. Immunity (2001) 4.62
Standard steroid treatment for autoimmune pancreatitis. Gut (2009) 4.33
Potential for transmission of avian influenza viruses to pigs. J Gen Virol (1994) 4.24
Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses. Int Immunol (1998) 4.14
Scoring system for the preoperative evaluation of metastatic spine tumor prognosis. Spine (Phila Pa 1976) (1990) 3.97
Affective picture processing: the late positive potential is modulated by motivational relevance. Psychophysiology (2000) 3.84
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. Cell (1998) 3.62
Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene. Genomics (1995) 3.60
Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase. J Biol Chem (1999) 3.55
Ly-C: a third locus specifying alloantigens expressed only on thymocytes and lymphocytes. Transplantation (1971) 3.42
Genetic organization of the chromosome region surrounding mecA in clinical staphylococcal strains: role of IS431-mediated mecI deletion in expression of resistance in mecA-carrying, low-level methicillin-resistant Staphylococcus haemolyticus. Antimicrob Agents Chemother (2001) 3.39
Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proc Natl Acad Sci U S A (1998) 3.35
Disruption of the mouse RBP-J kappa gene results in early embryonic death. Development (1995) 3.30
The role of influenza A virus hemagglutinin residues 226 and 228 in receptor specificity and host range restriction. J Virol (1998) 3.25
In vitro and in vivo activities of anti-influenza virus compound T-705. Antimicrob Agents Chemother (2002) 3.17
Conservation of the Notch signalling pathway in mammalian neurogenesis. Development (1997) 3.13
Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation. J Biol Chem (1997) 3.12
Sialic acid species as a determinant of the host range of influenza A viruses. J Virol (2000) 3.10
Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide. Leukemia (2012) 3.04
Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity. Nat Med (1996) 3.02
Incidence and risk factors of vascular dementia and Alzheimer's disease in a defined elderly Japanese population: the Hisayama Study. Neurology (1995) 2.99
Epidemiology, enteropathogenicity, and classification of Vi.rio parahaemolyticus. J Infect Dis (1965) 2.84
Atypical adenomatous hyperplasia of the lung. Implications for the pathogenesis of peripheral lung adenocarcinoma. Am J Clin Pathol (1999) 2.81
Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases. J Biol Chem (1996) 2.77
Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts. Mol Cell Biol (1994) 2.65
Effect of c-kit mutation on prognosis of gastrointestinal stromal tumors. Cancer Res (1999) 2.61
Transmission of bacteriocinogenicity by conjugation in group D streptococci. Jpn J Microbiol (1973) 2.60
Seroepidemiology of human herpesvirus 6 infection in normal children and adults. J Clin Microbiol (1989) 2.58
Impact of sarcopenia on survival in patients undergoing living donor liver transplantation. Am J Transplant (2013) 2.51
Frequency of choroidal abnormalities in neurofibromatosis type 1. Lancet (2000) 2.48
Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells. Oncogene (2006) 2.42
Periodic emission from the gamma-ray binary 1FGL J1018.6-5856. Science (2012) 2.40
Cross-coupling reactions of potassium alkyltrifluoroborates with aryl and 1-alkenyl trifluoromethanesulfonates. Org Lett (2001) 2.28
Angiographic no-reflow phenomenon as a predictor of adverse long-term outcome in patients treated with percutaneous transluminal coronary angioplasty for first acute myocardial infarction. J Am Coll Cardiol (2000) 2.20
A recombinant hepatitis C virus RNA-dependent RNA polymerase capable of copying the full-length viral RNA. J Virol (1999) 2.16
Survivin promotes cell proliferation in human hepatocellular carcinoma. Hepatology (2000) 2.15
Identification of a novel GC-rich 113-nucleotide region to complete the circular, single-stranded DNA genome of TT virus, the first human circovirus. J Virol (1999) 2.13
The POU domain transcription factor Brn-2 is required for the determination of specific neuronal lineages in the hypothalamus of the mouse. Genes Dev (1995) 2.11
Rho-associated kinase of chicken gizzard smooth muscle. J Biol Chem (1999) 2.10
Primary signet-ring cell carcinoma of the lung: histochemical and immunohistochemical characterization. Hum Pathol (1999) 2.07
Nitric oxide activity is deficient in spasm arteries of patients with coronary spastic angina. Circulation (1996) 2.06
Subcutaneous release of trigger thumb and fingers in 210 fingers. J Hand Surg Br (1990) 2.05
Two mouse piwi-related genes: miwi and mili. Mech Dev (2001) 2.05
Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE. J Biol Chem (1996) 2.05
Clinical features of a new disease concept, IgG4-related thyroiditis. Scand J Rheumatol (2013) 2.05
Lethal catatonia. Am J Psychiatry (1986) 2.03
Prognostic determinants of long-term survival in Japanese patients with cardiac sarcoidosis treated with prednisone. Am J Cardiol (2001) 2.03
Production of adiponectin, an anti-inflammatory protein, in mesenteric adipose tissue in Crohn's disease. Gut (2005) 2.03
Predominant expression of invariant V alpha 14+ TCR alpha chain in NK1.1+ T cell populations. Int Immunol (1995) 2.02
High incidence of amplification of the epidermal growth factor receptor gene in human squamous carcinoma cell lines. Cancer Res (1986) 1.98
Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation. J Clin Invest (1994) 1.97
The efficacy of mesenchymal stem cells to regenerate and repair dental structures. Orthod Craniofac Res (2005) 1.97
Hepatitis B virus genotype assignment using restriction fragment length polymorphism patterns. FEBS Lett (1999) 1.96
Interleukin 4 as an essential factor for in vitro clonal growth of murine connective tissue-type mast cells. J Exp Med (1987) 1.96
Acetoacetate metabolism in infant and adult rat brain in vitro. Biochem J (1970) 1.93
Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems. Proc Natl Acad Sci U S A (1999) 1.93
Resistance to Fas-mediated apoptosis: activation of caspase 3 is regulated by cell cycle regulator p21WAF1 and IAP gene family ILP. Oncogene (1998) 1.92
Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator. Mol Cell (1999) 1.91
Successful screening for early esophageal cancer in alcoholics using endoscopy and mucosa iodine staining. Cancer (1995) 1.91
Interleukin-3 and bryostatin-1 mediate hyperphosphorylation of BCL2 alpha in association with suppression of apoptosis. J Biol Chem (1994) 1.91
Characterization of a new avian-like influenza A virus from horses in China. Virology (1992) 1.90
Remnant lipoprotein levels in fasting serum predict coronary events in patients with coronary artery disease. Circulation (1999) 1.89
Interspecies transmission of influenza viruses: H5N1 virus and a Hong Kong SAR perspective. Vet Microbiol (2000) 1.86
Comet 81P/Wild 2 under a microscope. Science (2006) 1.83
Prevalence of antiseptic-resistance genes in Staphylococcus aureus and coagulase-negative staphylococci colonising nurses and the general population in Hong Kong. J Hosp Infect (2011) 1.82
Vancomycin-resistant Staphylococcus aureus occurs in South Africa. S Afr Med J (2000) 1.79
Influence of host species on the evolution of the nonstructural (NS) gene of influenza A viruses. Virus Res (1998) 1.78
Atypical adenomatous hyperplasia and bronchoalveolar lung carcinoma. Analysis by morphometry and the expressions of p53 and carcinoembryonic antigen. Am J Surg Pathol (1996) 1.77
A radioimmunoassay for aldosterone in human peripheral plasma including a comparison of alternate techniques. J Clin Endocrinol Metab (1972) 1.77
An increase in the serum amylase level in patients after peroral double-balloon enteroscopy: an association with the development of pancreatitis. Endoscopy (2006) 1.77
Rapamycin causes upregulation of autophagy and impairs islets function both in vitro and in vivo. Am J Transplant (2011) 1.76
Increased von Willebrand factor in the endocardium as a local predisposing factor for thrombogenesis in overloaded human atrial appendage. J Am Coll Cardiol (2001) 1.75
Comparison of stem-cell-mediated osteogenesis and dentinogenesis. J Dent Res (2003) 1.75
Role of endogenous nitric oxide in airway microvascular leakage induced by inflammatory mediators. Eur Respir J (1997) 1.74
Detection of 16 gamma-ray pulsars through blind frequency searches using the Fermi LAT. Science (2009) 1.74
Calcium-induced phase separations in phosphatidylserine--phosphatidylcholine membranes. Biochemistry (1974) 1.71
HPC-1 is associated with synaptotagmin and omega-conotoxin receptor. J Biol Chem (1992) 1.71
Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis. J Bone Miner Res (2000) 1.71
Patients with idiopathic cardiomyopathy belong to the same mitochondrial DNA gene family of Parkinson's disease and mitochondrial encephalomyopathy. Biochem Biophys Res Commun (1991) 1.70