Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: reduction of MRNA levels for interleukin-1beta, interleukin-6, cyclooxygenase-2, and p22phox by regulation of peroxisome proliferator-activated receptor alpha (PPARalpha) in primary endothelial cells.

PubWeight™: 1.30‹?› | Rank: Top 10%

🔗 View Article (PMID 10946846)

Published in Life Sci on July 14, 2000

Authors

I Inoue1, S Goto, K Mizotani, T Awata, T Mastunaga, S Kawai, T Nakajima, S Hokari, T Komoda, S Katayama

Author Affiliations

1: Fourth Department of Internal Medicine, Saitama Medical School, Iruma-gun, Japan.

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