Published in J Exp Med on December 01, 1977
Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. Proc Natl Acad Sci U S A (1980) 22.30
Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src). Proc Natl Acad Sci U S A (1979) 7.55
A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation. Mol Cell Biol (1984) 6.40
Construction and isolation of a transmissible retrovirus containing the src gene of Harvey murine sarcoma virus and the thymidine kinase gene of herpes simplex virus type 1. J Virol (1981) 4.54
A normal cell protein similar in structure and function to the avian sarcoma virus transforming gene product. Proc Natl Acad Sci U S A (1979) 4.02
Rous sarcoma virus variants that carry the cellular src gene instead of the viral src gene cannot transform chicken embryo fibroblasts. Proc Natl Acad Sci U S A (1984) 3.70
DNA and RNA from uninfected vertebrate cells contain nucleotide sequences related to the putative transforming gene of avian myelocytomatosis virus. J Virol (1979) 3.68
Cellular information in the genome of recovered avian sarcoma virus directs the synthesis of transforming protein. Proc Natl Acad Sci U S A (1979) 3.66
Characterization of Y73, an avian sarcoma virus: a unique transforming gene and its product, a phosphopolyprotein with protein kinase activity. Proc Natl Acad Sci U S A (1980) 3.58
Low level of cellular protein phosphorylation by nontransforming overproduced p60c-src. Mol Cell Biol (1985) 3.39
Recombination between viral and cellular sequences generates transforming sarcoma virus. Proc Natl Acad Sci U S A (1978) 3.38
DNA sequence of the viral and cellular src gene of chickens. 1. Complete nucleotide sequence of an EcoRI fragment of recovered avian sarcoma virus which codes for gp37 and pp60src. J Virol (1982) 3.35
Identification of a Rous sarcoma virus transformation-related protein in normal avian and mammalian cells. Proc Natl Acad Sci U S A (1979) 3.31
Temperature-sensitive transformation by Rous sarcoma virus and temperature-sensitive protein kinase activity. J Virol (1980) 3.25
Recombinants between endogenous and exogenous avian tumor viruses: role of the C region and other portions of the genome in the control of replication and transformation. J Virol (1980) 2.93
Biochemical and immunological characterization of polyproteins coded for by the McDonough, Gardner-Arnstein, and Snyder-Theilen strains of feline sarcoma virus. J Virol (1980) 2.92
Origin and functional properties of the major gene product of the Snyder-Theilen strain of feline sarcoma virus. Proc Natl Acad Sci U S A (1980) 2.83
Activation of the transforming potential of p60c-src by a single amino acid change. Proc Natl Acad Sci U S A (1986) 2.70
Cellular sequences related to three new onc genes of avian sarcoma virus (fps, yes, and ros) and their expression in normal and transformed cells. J Virol (1982) 2.69
Fine structural mapping of a critical NH2-terminal region of p60src. Proc Natl Acad Sci U S A (1985) 2.53
Homology exists among the transforming sequences of avian and feline sarcoma viruses. Proc Natl Acad Sci U S A (1980) 2.50
DNA sequence of the viral and cellular src gene of chickens. II. Comparison of the src genes of two strains of avian sarcoma virus and of the cellular homolog. J Virol (1982) 2.46
In vitro isolation of stable rat sarcoma viruses. Proc Natl Acad Sci U S A (1978) 2.41
N-terminal deletions in Rous sarcoma virus p60src: effects on tyrosine kinase and biological activities and on recombination in tissue culture with the cellular src gene. Mol Cell Biol (1985) 2.32
Molecular events in cells transformed by Rous Sarcoma virus. J Cell Biol (1980) 2.10
Involvement of directly repeated sequences in the generation of deletions of the avian sarcoma virus src gene. J Virol (1983) 1.94
Comparison between the viral transforming gene (src) of recovered avian sarcoma virus and its cellular homolog. Mol Cell Biol (1981) 1.78
Generation of transforming viruses in cultures of chicken fibroblasts infected with an avian leukosis virus. J Virol (1981) 1.68
Construction and isolation of a transforming murine retrovirus containing the src gene of Rous sarcoma virus. J Virol (1983) 1.63
Some biological properties of two new avian sarcoma viruses. J Virol (1981) 1.57
Chromosomal assignment of a family of human oncogenes. Proc Natl Acad Sci U S A (1983) 1.53
Characterization of some isolates of newly recovered avian sarcoma virus. J Virol (1979) 1.51
gag-Related polypeptides encoded by replication-defective avian oncoviruses. J Virol (1979) 1.48
Genetic analysis of p60v-src domains involved in the induction of different cell transformation parameters. J Virol (1986) 1.38
Relationship of polypeptide products of the transforming gene of Rous sarcoma virus and the homologous gene of vertebrates. Proc Natl Acad Sci U S A (1980) 1.38
Regulation of the SRC family kinases by Csk. Int J Biol Sci (2012) 1.36
Molecular mechanism for the capture and excision of the transforming gene of avian sarcoma virus as suggested by analysis of recombinant clones. J Virol (1980) 1.31
Recombination between a defective retrovirus and homologous sequences in host DNA: reversion by patch repair. J Virol (1985) 1.24
Evidence for the common origin of viral and cellular sequences involved in sarcomagenic transformation. J Virol (1980) 1.17
Analysis of the src gene of sarcoma viruses generated by recombination between transformation-defective mutants and quail cellular sequences. J Virol (1979) 1.17
Hyaluronan activates cell motility of v-Src-transformed cells via Ras-mitogen-activated protein kinase and phosphoinositide 3-kinase-Akt in a tumor-specific manner. Mol Biol Cell (2001) 1.08
NH2-terminal sequences of two src proteins that cause aberrant transformation. Proc Natl Acad Sci U S A (1987) 1.05
Induction of tumors and generation of recovered sarcoma viruses by, and mapping of deletions in, two molecularly cloned src deletion mutants. J Virol (1984) 1.04
Participation of subgenomic retroviral mRNAs in recombination. J Virol (1982) 1.04
src Genes of ten Rous sarcoma virus strains, including two reportedly transduced from the cell, are completely allelic; putative markers of transduction are not detected. J Virol (1981) 1.01
Isolation of 16L virus: a rapidly transforming sarcoma virus from an avian leukosis virus-induced sarcoma. Proc Natl Acad Sci U S A (1982) 0.99
Lack of induction of neuroretinal cell proliferation by Rous sarcoma virus variants that carry the c-src gene. Mol Cell Biol (1985) 0.95
Genome structure of HBI, a variant of acute leukemia virus MC29 with unique oncogenic properties. J Virol (1983) 0.93
Carboxyl-terminal determinants of Abelson protein important for lymphoma induction. J Virol (1991) 0.93
Homologous recombination between a defective virus and a chromosomal sequence in mammalian cells. Proc Natl Acad Sci U S A (1985) 0.90
Modulating effects of the extracellular sequence of the human insulinlike growth factor I receptor on its transforming and tumorigenic potential. J Virol (1993) 0.90
Abelson murine leukemia virus variants with increased oncogenic potential. J Virol (1986) 0.88
Transduction of c-src coding and intron sequences by a transformation-defective deletion mutant of Rous sarcoma virus. J Virol (1986) 0.88
Transformation by rat-derived oncogenic retroviruses. Microbiol Rev (1981) 0.86
Homologous interference resulting from the presence of defective particles of human immunodeficiency virus type 1. J Virol (1995) 0.84
Stimulation of growth rate of chondrocytes by Rous sarcoma virus is not coordinated with other expressions of the src gene phenotype. J Virol (1980) 0.84
Rous sarcoma virus mutant dlPA105 induces different transformed phenotypes in quail embryonic fibroblasts and neuroretina cells. J Virol (1987) 0.83
Transduction of the cellular src gene and 3' adjacent sequences in avian sarcoma virus PR2257. J Virol (1989) 0.83
Apparent uncoupling of oncogenicity from fibroblast transformation and apoptosis in a mutant myc gene transduced by feline leukemia virus. J Virol (1996) 0.78
A peptide & peptide nucleic acid synthesis technology for transporter molecules and theranostics--the SPPS. Int J Med Sci (2014) 0.77
Transgene expression facilitated by the v-src splice acceptor can impair replication kinetics and lead to genomic instability of Rous sarcoma virus-based vectors. J Virol (2007) 0.77
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Transduction of proto-src sequences in tissue culture by a molecular clone of transformation-defective Rous sarcoma virus with an internal src deletion. J Virol (1988) 0.75
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DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature (1976) 9.81
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Spontaneous segregation of nontransforming viruses from cloned sarcoma viruses. Virology (1971) 5.75
Gel electrophoresis of avian leukosis and sarcoma viral RNA in formamide: comparison with other viral and cellular RNA species. J Virol (1973) 5.70
A virus-induced rhabdomyosarcoma of mice. Natl Cancer Inst Monogr (1966) 5.61
Studies on the nucleic acid sequences of Kirsten sarcoma virus: a model for formation of a mammalian RNA-containing sarcoma virus. J Virol (1973) 5.28
Rapid transformation of cells by Rous sarcoma virus. Proc Natl Acad Sci U S A (1969) 5.27
Purification of DNA complementary to nucleotide sequences required for neoplastic transformation of fibroblasts by avian sarcoma viruses. J Mol Biol (1976) 5.07
Size and genetic content of viral RNAs in avian oncovirus-infected cells. J Virol (1977) 5.00
Genetic recombination with avian tumor virus. Virology (1972) 4.23
Studies on the nature and genetic control of an antigen in normal chick embryos which reacts in the COFAL test. J Gen Virol (1968) 4.11
Mapping of biological functions on RNA of avian tumor viruses: location of regions required for transformation and determination of host range. Proc Natl Acad Sci U S A (1975) 4.01
The a subunit in the RNA of transforming avian tumor viruses. I. Occurrence in different virus strains. II. Spontaneous loss resulting in nontransforming variants. Virology (1972) 3.95
Harvey sarcoma virus: a second murine type C sarcoma virus with rat genetic information. J Virol (1974) 3.92
Location of envelope-specific and sarcoma-specific oligonucleotides on RNA of Schmidt-Ruppin Rous sarcoma virus. Proc Natl Acad Sci U S A (1976) 3.73
Avian tumor virus RNA: a comparison of three sarcoma viruses and their transformation-defective derivatives by oligonucleotide fingerprinting and DNA-RNA hybridization. Proc Natl Acad Sci U S A (1973) 3.46
A cell-associated factor essential for formation of an infectious form of Rous sarcoma virus. Proc Natl Acad Sci U S A (1970) 3.43
Separation of sarcoma virus-specific and leukemia virus-specific genetic sequences of Moloney sarcoma virus. Proc Natl Acad Sci U S A (1975) 3.28
Recovery of a new virus from apparently normal chick cells by infection with avian tumor viruses. Proc Natl Acad Sci U S A (1970) 2.99
Nucleotide sequence relationships of avian RNA tumor viruses: measurement of the deletion in a transformation-defective mutant of Rous sarcoma virus. J Virol (1974) 2.61
Fractionation of DNA nucleotide transcripts from Moloney sarcoma virus and isolation of sarcoma virus-specific complementary DNA. J Virol (1976) 2.39
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Isolation of different kinds of non-virus producing chick cells transformed by Schmidt-Ruppin strain (subgroup A) of Rous sarcoma virus. Jpn J Exp Med (1970) 2.35
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Genetic variation in the RNA transcripts of endogenous virus genes in uninfected chicken cells. J Virol (1977) 2.28
Recombination between endogenous and exogenous RNA tumor virus genes as analyzed by nucleic acid hybridization. J Virol (1975) 2.14
Rat sequences of the Kirsten and Harvey murine sarcoma virus genomes: nature, origin, and expression in rat tumor RNA. J Virol (1976) 1.99
Transformation-defective mutants of avian sarcoma viruses: the genetic relationship between conditional and nonconditional mutants. Virology (1976) 1.75
Chicken macrochromosomes contain an endogenous provirus and microchromosomes contain sequences related to the transforming gene of ASV. Cell (1977) 1.61
Derivation of mouse sarcoma virus (Kirsten) by acquisition of genes from heterologous host. J Gen Virol (1975) 1.44
Genetic control of expression of endogenous virus genes in chicken cells. Virology (1974) 1.37
35S a and b RNA subunits of avian RNA tumor virus strains cloned and passaged in chick and duck cells. Cold Spring Harb Symp Quant Biol (1975) 1.24
Evidence for naturally occurring murine sarcoma virus. Nature (1973) 0.99
New procedure for DNA transfection with polycation and dimethyl sulfoxide. Mol Cell Biol (1984) 8.63
The effects of reciprocal changes in temperature on the transformed state of cells infected with a rous sarcoma virus mutant. Virology (1971) 7.83
Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus. Cell (1983) 7.37
A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation. Mol Cell Biol (1984) 6.40
A novel viral oncogene with structural similarity to phospholipase C. Nature (1988) 5.84
Rapid transformation of cells by Rous sarcoma virus. Proc Natl Acad Sci U S A (1969) 5.27
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Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides. Nature (1992) 4.46
Genetic recombination with avian tumor virus. Virology (1972) 4.23
Cell transformation by the viral src oncogene. Annu Rev Cell Biol (1987) 4.18
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An N-terminal peptide from p60src can direct myristylation and plasma membrane localization when fused to heterologous proteins. Nature (1985) 4.06
Amino terminal myristylation of the protein kinase p60src, a retroviral transforming protein. Science (1985) 3.97
Characterization of protein kinase activity associated with the transforming gene product of Fujinami sarcoma virus. Cell (1980) 3.82
The erbB gene of avian erythroblastosis virus is a member of the src gene family. Cell (1983) 3.82
Location of envelope-specific and sarcoma-specific oligonucleotides on RNA of Schmidt-Ruppin Rous sarcoma virus. Proc Natl Acad Sci U S A (1976) 3.73
Rous sarcoma virus variants that carry the cellular src gene instead of the viral src gene cannot transform chicken embryo fibroblasts. Proc Natl Acad Sci U S A (1984) 3.70
Binding of transforming protein, P47gag-crk, to a broad range of phosphotyrosine-containing proteins. Science (1990) 3.67
Cellular information in the genome of recovered avian sarcoma virus directs the synthesis of transforming protein. Proc Natl Acad Sci U S A (1979) 3.66
Proteins of helper-dependent RSV. Virology (1971) 3.62
Characterization of Y73, an avian sarcoma virus: a unique transforming gene and its product, a phosphopolyprotein with protein kinase activity. Proc Natl Acad Sci U S A (1980) 3.58
Transformation by Rous sarcoma virus induces a novel gene with homology to a mitogenic platelet protein. Cell (1987) 3.50
Local mutagenesis of Rous sarcoma virus: the major sites of tyrosine and serine phosphorylation of pp60src are dispensable for transformation. Cell (1983) 3.46
A cell-associated factor essential for formation of an infectious form of Rous sarcoma virus. Proc Natl Acad Sci U S A (1970) 3.43
Low level of cellular protein phosphorylation by nontransforming overproduced p60c-src. Mol Cell Biol (1985) 3.39
Recombination between viral and cellular sequences generates transforming sarcoma virus. Proc Natl Acad Sci U S A (1978) 3.38
Isolation of defective mutant of avian sarcoma virus. Proc Natl Acad Sci U S A (1973) 3.38
DNA sequence of the viral and cellular src gene of chickens. 1. Complete nucleotide sequence of an EcoRI fragment of recovered avian sarcoma virus which codes for gp37 and pp60src. J Virol (1982) 3.35
DNA in uninfected and virus-infected cells complementary to avian tumor virus RNA. Proc Natl Acad Sci U S A (1971) 3.25
Evidence for a transcriptional activation function of BRCA1 C-terminal region. Proc Natl Acad Sci U S A (1996) 3.18
Viral and cellular src genes contribute to the structure of recovered avian sarcoma virus transforming protein. Cell (1981) 3.12
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Molecular cloning and characterization of a surface antigen preferentially overexpressed on multiple myeloma cells. Biochem Biophys Res Commun (1999) 3.03
Recovery of a new virus from apparently normal chick cells by infection with avian tumor viruses. Proc Natl Acad Sci U S A (1970) 2.99
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Analysis of a functional change in membrane in the process of cell transformation by Rous sarcoma virus; alteration in the characteristics of sugar transport. Virology (1970) 2.94
Presence of murine leukemia virus envelope proteins gp70 and p15(E) in a common polyprotein of infected cells. J Virol (1976) 2.91
Determining factor in the capacity of Rous sarcoma virus to induce tumors in mammals. Proc Natl Acad Sci U S A (1966) 2.86
Detection of avian tumor virus RNA in uninfected chicken embryo cells. J Virol (1973) 2.85
Amino acid substitutions sufficient to convert the nontransforming p60c-src protein to a transforming protein. Mol Cell Biol (1986) 2.84
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Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases. J Biol Chem (1996) 2.77
Activation of the transforming potential of p60c-src by a single amino acid change. Proc Natl Acad Sci U S A (1986) 2.70
Cellular sequences related to three new onc genes of avian sarcoma virus (fps, yes, and ros) and their expression in normal and transformed cells. J Virol (1982) 2.69
c-Abl kinase regulates the protein binding activity of c-Crk. EMBO J (1994) 2.68
Characterization of the transforming gene of Fujinami sarcoma virus. Proc Natl Acad Sci U S A (1980) 2.68
TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src. Mol Cell (1999) 2.64
A type of chick embryo cell that fails to support formation of infectious RSV. Virology (1970) 2.63
Fine structural mapping of a critical NH2-terminal region of p60src. Proc Natl Acad Sci U S A (1985) 2.53
Unifected avian cells contain structurally unrelated progenitors of viral sarcoma genes. Nature (1980) 2.50
Homology exists among the transforming sequences of avian and feline sarcoma viruses. Proc Natl Acad Sci U S A (1980) 2.50
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Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts. Mol Cell Biol (1993) 2.47
DNA sequence of the viral and cellular src gene of chickens. II. Comparison of the src genes of two strains of avian sarcoma virus and of the cellular homolog. J Virol (1982) 2.46
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Transformation-defective mutants of Rous sarcoma virus with src gene deletions of varying length. J Virol (1977) 2.43
Microinjection analysis of envelope-glycoprotein messenger activities of avian leukosis viral RNAs. Proc Natl Acad Sci U S A (1977) 2.42
Processing of p60v-src to its myristylated membrane-bound form. Mol Cell Biol (1985) 2.41
Only membrane-associated RSV src proteins have amino-terminally bound lipid. Nature (1983) 2.37
RNA of replication-defective strains of Rous sarcoma virus. Proc Natl Acad Sci U S A (1975) 2.37
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N-terminal deletions in Rous sarcoma virus p60src: effects on tyrosine kinase and biological activities and on recombination in tissue culture with the cellular src gene. Mol Cell Biol (1985) 2.32
Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries. Mol Cell Biol (1988) 2.31
Genetic variation in the RNA transcripts of endogenous virus genes in uninfected chicken cells. J Virol (1977) 2.28
v-maf, a viral oncogene that encodes a "leucine zipper" motif. Proc Natl Acad Sci U S A (1989) 2.24
Analysis of the binding of the Src homology 2 domain of Csk to tyrosine-phosphorylated proteins in the suppression and mitotic activation of c-Src. Proc Natl Acad Sci U S A (1994) 2.24
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Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma. Cancer Res (1993) 2.22
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Noninfectious RSV deficient in DNA polymerase. Virology (1971) 2.18
Two cellular proteins that immunoprecipitate with the transforming protein of Rous sarcoma virus. Virology (1981) 2.16
Avian sarcoma virus UR2 encodes a transforming protein which is associated with a unique protein kinase activity. J Virol (1982) 2.14
Recombination between endogenous and exogenous RNA tumor virus genes as analyzed by nucleic acid hybridization. J Virol (1975) 2.14
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Further studies on RSV production form transformed cells. Virology (1968) 1.97
A new avian erythroblastosis virus, AEV-H, carries erbB gene responsible for the induction of both erythroblastosis and sarcomas. Cell (1983) 1.95
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Identification of domains of the v-crk oncogene product sufficient for association with phosphotyrosine-containing proteins. Mol Cell Biol (1991) 1.92
Plaque assay for some strains of avian leukosis virus. Virology (1972) 1.87
A cellular protein is immunologically crossreactive with and functionally homologous to the Fujinami sarcoma virus transforming protein. Cell (1982) 1.86
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